APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Shuo Yu,Caixia Huo,Kui Hao,Le Sun,Yuqing Peng,Aijun Li
We report a novel mild self-assembly freeze–thaw strategy for fabricating 3D graphene aerogel (GA) composite anchored with SnO 2 nanoparticles. Compared with conventional hydrothermal and freeze-drying methods, The method achieves energy-efficient synthesis (90 °C, 3 h) and eliminates complex equipment. Efficient dispersion of SnO 2 nanoparticles and precise modulation of the 3D porous structure were achieved through the synergistic effects of self-assembly, foaming, and in-situ reduction at low temperature and atmospheric pressure. The unique structure of GA/SnO 2 composites significantly buffers the volume expansion of SnO 2 and enhances the ion/electron transport kinetics. As a sodium-ion battery anode, it provides a high reversible capacity of 302.5 mAh g −1 after 300 cycles at 0.1 A g −1 and a remarkable rate capability (146 mAh g −1 at 2 A g −1 ), outperforming aggregated SnO 2 synthesized via hydrothermal routes. DFT simulations reveal enhanced sodium-ion adsorption energy and interfacial C Sn O covalent bonding, which synergistically stabilize the electrode structure. This work provides a low-cost and environmentally friendly route for designing high-performance metal oxide/carbon composites.
研究领域:
材料科学
·
能源存储
·
纳米技术
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Dongao Liu,Lei Li,Quanxin Gong,Gui Du,Yuhua Xue,Guisheng Li,Shengjuan Li
Developing high-performance and cost-effective microwave-absorbing materials for large-scale production is crucial in addressing the current electromagnetic pollution problem. This has become a focus of scientific research. This study proposes a cost-effective freeze-thaw method to enable large-scale production of MXene-based flexible films. This method streamlines the preparation process and produces ultrathin flexible MXene/CNF composite films with a multidimensional layered structure. The multidimensional layered structure provides additional scattering and reflecting paths for electromagnetic waves, increasing the interaction time between electromagnetic waves and the material. Additionally, the redistributed interfacial charge enhances the dielectric loss and electromagnetic shielding performance for the shielding material, thereby improving microwave absorption efficiency. Owing to these advantages, the MXene/CNF composite films prepared using the freeze-thaw method exhibit excellent electromagnetic shielding and mechanical properties. The conductivity of the composite film can reach 165.9 S cm −1 with a shielding effectiveness of 54.7 dB, and a high efficiency of 99.74 %. According to the simulations using a finite element method (FEM), the arrangement and rotation angles of all CNF layers significantly affect the electromagnetic shielding effectiveness of the MXenen/CNF composite films.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Haohao Chen,Min Yuan,Fengqin Yin,Hui Cao,Xiuxiu Wu,Liling Hao,Weiyan Shi,Tai Ye,Fei Xu
The traditional nucleic acid-modified electrode in room-temperature manner suffers from the drawback of time-consuming and uneven distribution. In this work, we adopted the freeze-thawing method to construct a nicking enzyme-powered DNA walking machine on the gold electrode. In the absence of kanamycin, the intact substrate strand can trigger the self-assembly and form G4 nanowires on the electrode surface. After adding hemin, a significant catalytic current of the TMB oxidization can be observed. By contrast, once the specific binding between aptamer and kanamycin occurs, the activated walking strand processes a consecutive binding-cleavage cycle with the substrate strand on the electrode surface. The residue substrate fragment is unable to trigger the subsequent G-quadruplex assembly, resulting in a decrease in catalytic current. Under optimal experimental conditions, a linear relationship between the kanamycin concentration and current decrease was obtained in the range from 5 to 100 pM, and the limit of detection was 1.44 pM. This method has also demonstrated practical performance in the spiked milk and honey with satisfactory recoveries of 107.1 % to 114.3 % and 94.3 % to 101.5 %, respectively.
研究领域:
生物化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Carbohydrate Polymer Technologies and Applications
·
2025
·
IF 6.5
Fengxiang Huang,Di Yang,Guohui Bai,Diansan Su,Zhaoqiong Zhu,Yuanzhu Long
Chitosan sponges hold significant promise for advanced wound dressings; however, their widespread adoption is hindered by complex and costly fabrication processes that depend on organic solvents, lyophilization, and alkaline immersion. Here, we introduce a novel organic-solvent-free freeze-thaw strategy to overcome these challenges. The integration of ammonium bicarbonate into acetic acid-dissolved chitosan, followed by a single freeze-thaw cycle (freezing at -20°C and thawing at 26°C within 1 hour), results in the spontaneous formation of pure chitosan sponges. The resulting material exhibits exceptional tensile strength (26.35 kPa at 1.57% solid content) without the use of potentially harmful crosslinkers. This approach eliminates the need for energy-intensive lyophilization and organic solvents, thereby reducing production time and cost by over 90% compared to traditional methods. In vivo studies using SD rat models demonstrate 67% faster epithelialization compared to gauze controls, along with full biocompatibility attributed to the inherent biological properties of pure chitosan. With minimal equipment requirements, environmental sustainability, and high scalability, this method establishes a new benchmark for biomaterial manufacturing. Its potential for clinical translation in emergency wound care and tissue engineering applications is underscored, pending further validation.
研究领域:
材料科学
·
生物医学工程
·
组织工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Han Dong,Letian Zhong,Yuliang Cheng,Hang Yu,Yunfei Xie,Weirong Yao,Yahui Guo,Hideya Kawasaki
The freezing method used to prepare DNA-modified gold nanoparticles (SNA) has the advantages of being fast and simple, but the prepared SNA is easy to aggregate. In this paper, the effects of polyethylene glycol (PEG) as an organic macromolecular crowding agent on the single-strand polyadenylate DNA functionalized gold nanoparticles (polyA-SNA) and the single-strand thiolated DNA functionalized gold nanoparticles (HS-SNA) were systematically studied. The experimental results showed the molecular weight and concentration of PEG significantly affect the dispersion and DNA loading of the two kinds of SNA . An increase in DNA strand length inhibits the adsorption of thiolated DNA and polyA-DNA, and the hydrated particle size of SNA increases at first and then decreases with the length of the DNA strand. These phenomena lay on the speculative principle that PEG improved the energy barrier for gold nanoparticles (AuNPs) aggregation through the long chain of macromolecules , and the modification mode and length of surface DNA also play an auxiliary role. This work provided a systematic study and helpful results on improving the stability of SNA prepared by the freezing method.
研究领域:
生物化学
·
纳米医学
✓ 已验证
DOI
高影响因子
Science China-Technological Sciences
·
2023
·Vol. 66
·期 8
·2213-2224
·
IF 4.6
Li Qiang,Wu Chao,Peng YaJun,Zhang BingJian
Developing advanced cleaning systems for the removal of unwanted layers from painted surfaces is still a challenging issue that needs to be addressed in the field of cultural heritage. In this work, we proposed the use of novel polyelectrolyte hydrogels prepared via free radical polymerization and freeze-thaw methods. Zwitterionic sulfobetaine methacrylate (SBMA) was cross-linked with methylacryloyloxyethyl trimethylammonium (DMC) through covalent bonding to yield zwitterionic polyelectrolyte poly(SBMA- co -DMC) (PSD). Introducing PSD into the polyvinyl alcohol/carboxymethyl chitosan (PVA/CMC) hydrogel network enhanced the intermolecular electrostatic interactions and changed the porous structure and swelling behaviors, thus leading to improved mechanical properties. The adsorption ability of the PVA/CMC/PSD polyelectrolyte hydrogels toward dyes (rhodamine B and congo red) and metal ions (Cu 2+ and K + ) varied with increasing amounts of PSD, which could be attributed to cationic PSD tuning the net charges in the hydrogel. The cleaning effectiveness of the PVA/CMC/PSD polyelectrolyte hydrogels was assessed on wall painting mock-ups coated with soil, red paint, and soluble salts, using microscopic and spectroscopic analyses. The results showed that the hydrogel adhered to rough surfaces and removed unwanted substances effectively without leaving determinable residues, providing a possible safe and efficient method for the cleaning of important artifacts.
研究领域:
文化遗产保护
·
材料科学
·
高分子化学
·
分析化学
·
表面清洁
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Dandan Wei,Yulin Huang,Min Liang,Liuxin Yang,Guanhua Jiao,Yinghua Tao,Li Xu,Tianzhu Zhang,Zhenling Ji
Polypropylene (PP) mesh is the most widely used prosthetic material in hernia repair. However, the efficacy of implanted PP mesh is often compromised by adhesion between viscera and PP mesh. Thus, there is a recognized need for developing an anti-adhesive PP mesh. Here, a composite hydrogel coated PP mesh with the prevention of adhesion after hernia repair was designed. The composite hydrogel coating was prepared from polyvinyl alcohol (PVA) and hyaluronic acid (HA) by using the freezing-thawing (FT) method. To overcome the shortcoming of the long time of the traditional freezing-thawing method, a small molecule 3,4-dihydroxyphenylacetic acid (DHPA) was introduced to promote the formation of composite hydrogel. The as-prepared composite hydrogel coating displayed modulus more closely resembling that of native abdominal wall tissue. In vitro studies illustrated that the resulting meshes showed excellent coating stability, hemocompatibility, and non-cytotoxicity. In vivo experiments using a rat abdominal wall defect model demonstrated that the composite hydrogel coated PP mesh could prevent the formation of adhesion, alleviate the inflammatory response, and reduce the deposition of collagen around the damaged tissue. These disclosed results manifested that the PP mesh coated with HA/PVA composite hydrogel might be a promising application in preventing adhesion for hernia repair.
研究领域:
材料科学
·
生物医学工程
·
组织工程
·
外科材料
·
医疗器械
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 11
·e53612
·
IF 3
Xiaoshuang Zuo,Shan Ye,Onome Ejeromedoghene,Bin Wang,Bingbing Cui,Guodong Fu
Fabrication of composites with hierarchically anisotropic structure and excellent mechanical properties is still challenging. Inspired by biological tissues with excellent anisotropic microstructure, in this study, a simple method for preparing robust anisotropic polyvinyl alcohol/glass fiber (PVA/GFs) composites with superior mechanical properties was proposed, which based on hydrogen bonding interactions and freeze–thaw method under tensile conditions. Surface-initiated atom transfer radical polymerization (SI-ATRP) was applied for grafting polymers onto the glass fiber. The glass fibers grafted with polymers (GFs) were introduced into PVA. After that, the freeze–thaw method under tensile conditions was adopted to control the formation of hierarchically anisotropic structure, which composed of anisotropic polymer network and orderly aligned glass fibers. The results also showed that the strength and toughness of the composites were significantly improved, due to the interfacial hydrogen bonding interactions between PVA and GFs. Therefore, this study could provide a meaningful idea for preparing anisotropic biomaterials with prominent properties for artificial tissues.
研究领域:
材料科学
·
复合材料
·
高分子科学
·
机械工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Ling Ding,Shen Song,Lele Chen,Jipeng Shi,Baotang Zhao,Guixiang Teng,Ji Zhang
In this work, an innovative composite hydrogel composed of curdlan (CD)/polyvinyl alcohol (PVA) hydrogels with a 3-d network structure was successfully prepared by freeze-thaw processing. The presence of interactions, changes in crystallinity, and thermal behaviour were investigated by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and thermogravimetry (TGA and DTG), respectively. The morphology of the hydrogels was investigated by scanning electron microscopy (SEM). With the increase of PVA concentration, the composite hydrogel had a greater mechanical strength while remaining remarkably ductile as evinced by tensile test results. PVA content affects the swelling and water retention of CD/PVA hydrogels. The results of CCK-8 assay showed that CD/PVA hydrogels have no cytotoxic effect on the mouse fibroblast L929 cells. The AO/EB double-staining experiment further proved that the cells in the composite hydrogels had good cytocompatibility. The porous biohydrogels developed in the present work can provide an ideal cell growth environment as a scaffold. CD/PVA hydrogels highlight the value of this system for cell adhesion and proliferation, and further soft tissue engineering application.
研究领域:
材料科学
·
生物材料
·
组织工程
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2019
·Vol. 35
·期 3
·521-529
·
IF 1.071
Meng Deyue,Zhou Xiuqing,Zheng Keyan,Miao Chong,Sheng Ye,Zou Haifeng
Poly(vinyl alcohol)/hydroxyapatite(PVA/HA) composite hydrogel was successfully in-situ synthesized via three cycles of freezing-thawing. The composition and structure of products were investigated by X-ray diffraction(XRD), Fourier transformed infrared spectroscopy(FTIR) and scanning electron microscopy(SEM). The influence of different preparation methods and contents of material on the mechanical properties of PVA/HA composite hydrogel was discussed through tensile and compressive tests. The template of PVA could avoid the agglomeration of HA particles, which improves the mechanical properties of the composite hydrogel effectively. The tensile strength, modulus and compressive performances of the PVA/HA composite hydrogel prepared by the in-situ synthesis method were better than those of hydrogel obtained by the simple blend method. In addition, the effect of the content of PVA, HA, and the pH value on the properties of the PVA/HA composite hydrogel has been discussed in detail.
研究领域:
材料科学
·
生物医学工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Materials Research Express
·
2020
·Vol. 7
·期 1
·015413
·
IF 1.929
Ruixia Hou,Yuxi Wang,Jiali Han,Yabin Zhu,Hua Zhang,Libing Zhang,Liping Li,Kui Xu,Guanglei Fu,Xianbo Mou,Xi Chen,Lu Yang,Lei Nie
Controllable regulation of cell behavior is one of the most important factors conducive to the restoration of tissue functions. Recently, various strategies have been developed using physical or chemical cues. Although these techniques are effective, the high cost and complex fabrication procedures impede their application. In this study, we used a low cost and simple strategy to fabricate PVA/silk fibroin composite hydrogels using a cyclic freeze-thaw method. With the increase of freeze-thaw cycles, the pore size of hydrogels decreased, the elastic modulus increased, and the swelling rate decreased. Furthermore, we chose two shapes of model cells, a spindle using bone marrow mesenchymal stem cells and smooth muscle cells, and a round shape using BV2 microglial cells. PVA/silk fibroin composite hydrogels inhibited the adhesion and proliferation of stem cells and muscle cells and changed their cell shape from spindle to round, maintained the initial round shape of BV2 microglial cells, and promoted the proliferation of BV2 microglial cells. These results demonstrate that PVA/silk fibroin composite hydrogels can be used as a novel hydrogel system to regulate cell behavior.
研究领域:
材料科学
·
生物材料
·
细胞生物学
·
组织工程
✓ 已验证
DOI
高影响因子
JOURNAL OF PHYSICAL CHEMISTRY B
·
2025
·
IF 2.9
Haiyang Huang,Yong Zhou,Ling Xie,Bing Li,Wenlong Wang,Xinjuan Liu,Yongli Huang,Chang Q. Sun,Biao Wang
Hydrogels are versatile functional materials with applications in biomedical devices, sensors, and energy systems. However, tailoring their mechanical properties remains a critical challenge for expanding their practical utility. Here, the mechanical properties of poly(vinyl alcohol) (PVA) hydrogels prepared via the freeze–thaw method were effectively tailored through the incorporation of various chloride salts. This study reveals the molecular mechanisms by which salt ions influence the water structure, polymer chain interactions, and freezing behavior to modulate hydrogel performance. Using Raman spectroscopy, X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR), we elucidate how cation-specific effects alter the crystallinity, cross-linking density, and hydrogen bond network in the hydrogels. Hydrogels containing K+ exhibited superior rigidity and toughness due to enhanced crystallinity and optimized water–polymer interactions, while hydrogels of Mg2+ and Ca2+ had much lower modulus and adhesion strength since the divalent ions reduced freezing points resulting in reduced polymer aggregation. These findings provide a molecular-level understanding of the salting effects on hydrogel properties, offering new insights into designing materials with tunable mechanical performance for diverse applications.
研究领域:
材料科学
·
高分子科学
·
机械工程
·
生物医学工程
·
物理化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）