JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 128
·期 6
·3846-3852
·
IF 1.289
Hong Zhou,Yeping Xu,Hongwu Tong,Yuxin Liu,Fang Han,Xiangyang Yan,Shaomin Liu
Molecularly imprinted polymers (MIP) with high performance in selectively recognizing bisphenol A (BPA) were prepared by using a novel and facile surface molecular-imprinting technique. Vinyl-functionalized, monodispersed silica spheres were synthesized by a one-step emulsion reaction in aqueous solution. Then, BPA surface molecularly imprinted polymers (SMIP) were prepared by polymerization with 4-vinylpyridine as the functional monomer and ethylene glycol dimethacrylate as the crosslinker. Maximal sorption capacity ( Q max ) of the resulting SMIP was up to 600 μmol g −1 , while that of nonimprinted polymers was only 314.68 μmol g −1 . Kinetic binding study showed that sorption capacity reached 70% of Q max in 20 min and sorption equilibrium at 80 min. SMIP had excellent accessibility and affinity toward BPA, for the selectivity coefficients of SMIP for BPA in respect to phenol, p-tert -butylphenol, and o -phenylphenol were 3.39, 3.35, and 3.02, respectively. The reusage process verified the SMIP owning admirably stable adsorption capacity toward BPA for eight times. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2021
·Vol. 26
·期 19
·5965
·
IF 4.412
Xiaoxiao Chen,Yang Liu,Pu Li,Yichen Xing,Chaobiao Huang
A dual recognition system with a fluorescence quenching of quantum dots (QDs) and specific recognition of molecularly imprinted polymer (MIP) for the detection of chloramphenicol (CAP) was constructed. MIP@SiO2@QDs was prepared by reverse microemulsion method with 3-aminopropyltriethoxysilane (APTS), tetraethyl orthosilicate (TEOS) and QDs being used as the functional monomer, cross-linker and signal sources, respectively. MIP can specifically recognize CAP, and the fluorescence of QDs can be quenched by CAP due to the photo-induced electron transfer reaction between CAP and QDs. Thus, a method for the trace detection of CAP based on MIP@SiO2@QDs fluorescence quenching was established. The fluorescence quenching efficiency of MIP@SiO2@QDs displayed a desirable linear response to the concentration of CAP in the range of 1.00~4.00 × 102μmol × L−1, and the limit of detection was 0.35 μmol × L−1(3σ,n= 9). Importantly, MIP@SiO2@QDs presented good detection selectivity owing to specific recognition for CAP, and was successfully applied to quantify CAP in lake water with the recovery ranging 102.0~104.0%, suggesting this method has the promising potential for the on-site detection of CAP in environmental waters.Keywords:molecular imprinting;chloramphenicol;quantum dots;fluorescence quenching
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Dan Qiao,Zhen Zhang,Lingshuang Wang,Wei Sheng,Qiliang Deng,Shuo Wang
Test strips as one of micro-devices are widely concerned in the fields of point-of-care detection and in-field diagnosing. For the purpose of on-site detection of tyramine, a carbon dots-molecularly imprinted fluorescent sensing test strip with high selectivity has been successfully obtained via a rapid in-situ preparation procedure (about 2.5 h). Here, the layer composed of carbon dots-molecularly imprinted polymer (CDs-MIP) with the function of the recognition and signal transduce has been formed on the surface of the filter paper strips via the sol-gel method. The developed test strip displayed a high specificity (Imprinting factor, IF = 4.96); and its fluorescence emission was quenched linearly with the increase of tyramine concentration from 0.5 to 10.0 mg L −1 . The limit of detection (LOD) is 0.059 mg L −1 (3 σ/s ). The application potential was verified by sensing of tyramine in rice vinegar and white rice vinegar with the recoveries of 90.9-104.4% (RSD < 5.8%). Many advantages including a rapid preparation and high selectivity make the fluorescence strip suitable for on-site detection of tyramine. In addition, the preparation procedure can also be easily transferred to the preparation of the fluorescence strip toward other targets.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2017
·Vol. 9
·期 10
·469
·
IF 3.364
Yuxin Pei,Fengfeng Fan,Xinxin Wang,Weiwei Feng,Yong Hou,Zhichao Pei
To fabricate molecularly imprinted polymer nanospheres via click reaction, five different clickable compounds were synthesized and two types of click reactions (azide-alkyne and thiol-yne) were explored. It was found that molecularly imprinted polymer nanospheres could be successfully synthesized via thiol-yne click reaction using 3,5-diethynyl-pyridine (1) as the monomer, tris(3-mercaptopropionate) (tri-thiol,5) as the crosslinker, and hypericin as the template (MIP–NSHs). The click polymerization completed in merely 4 h to produce the desired MIP–NSHs, which were characterized by FTIR, SEM, DLS, and BET, respectively. The reaction conditions for adsorption capacity and selectivity towards hypericin were optimized, and the MIP–NSHs synthesized under the optimized conditions showed a high adsorption capacity (Q= 6.03 μmol·g−1) towards hypericin. The imprinting factors of MIP–NSHs towards hypericin, protohypericin, and emodin were 2.44, 2.88, and 2.10, respectively.Keywords:molecular imprinting;hypericin;click reaction;nanospheres
研究领域:
材料科学
·
药物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemosensors
·
2022
·Vol. 10
·期 11
·437
·
IF 4.229
Caiyun Jiang,Ting Wu,Xin He,Yuping Wang,Hong-zhen Lian
To this day, the preparation of surface-enhanced Raman spectroscopy (SERS) substrates with high sensitivity, selectivity, and stability has been the bottleneck to realizing SERS-based quantitative analysis in practical applications. In this paper, a thermo-sensitive imprinting SERS substrate material (TM@TiO2@Ag) is developed with a uniform structure and morphology, a controllable “hot spot” and photocatalytic regeneration. The as-prepared TM@TiO2@Ag nanocomposite is characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, ultraviolet–visible (UV-Vis) spectroscopy, etc. After the effects of its thermo-sensitive property on localized surface plasmon resonance (LSPR) and SERS signals are investigated, this nanomaterial is used as the Raman-enhanced substrate for rapid and trace detection of ofloxacin (OFL) in water. It is found that, with the aid of unique structure and composition, temperature sensitivity, and molecule imprinting, the SERS sensor possesses considerably strong anti-interference ability not only to structure-unlike but also to structure-like co-existing substances, extremely low detectable concentration of 1.1 × 10−11M for OFL at 1397 cm−1, as well as excellent reusability due to its photocatalytic degradation to target analytes.Keywords:SERS;molecule imprinting;thermo-sensitive;recyclability;ofloxacin (OFL)
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2012
·Vol. 35
·期 8
·1036-1043
·
IF 2.733
Wen Zhan,Fangdi Wei,Guanhong Xu,Zheng Cai,Shuhu Du,Xuemin Zhou,Fei Li,Qin Hu
A water compatible molecularly imprinted polymers (MIPs) coated stir bar for bisphenol A(BPA) was prepared with 3,3′,5,5′-tetrabromobisphenol A as the dummy template molecule in this study. The dummy molecularly imprinted polymers coated stir bar (DMIPs-SB) showed better selectivity than the bars coated with polydimethylsiloxane or non-imprinted polymers when used to extract BPA and its three analogues. The saturated adsorption amount of the DMIPs coating was 3.0 times over that of the non-imprinted polymers coating. To achieve the optimum extraction performance, several parameters, including extraction and desorption time, pH value, adsorption temperature and stirring speed were investigated. The high-performance liquid chromatography combined with the DMIPs-SB was employed in the analysis of BPA in aqueous solution. The linear range of BPA concentration in aqueous medium was 0.0228–2.28 ng/mL with correlation coefficient of 0.9994 and the detection limit was about 6.84 × 10 −3 ng/mL based on three times ratio of signal to noise. This method was directly applied to the determination of trace BPA in milk with satisfactory results.
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
TALANTA
·
2015
·
IF 3.545
Wei Chen,Min Xue,Fei Xue,Xiangrong Mu,Zhibin Xu,Zihui Meng,Guangxian Zhu,Kenneth J. Shea
Solid phase extraction (SPE) is widely used in many different areas, such as environmental, biological, and food analysis, where cleaning and pre-concentration of samples are key steps in the analytical protocol. New materials have significant impact on the development of solid phase extraction. In this paper, mono-dispersed molecularly imprinted hollow spheres (MIHSs) of β -estradiol (E2) were synthesized using silica nanospheres particles as the sacrificial matrix. Compared to the corresponding non-imprinted hollow spheres (NIHSs), the MIHSs with uniform size of 290 nm have outstanding affinity in aqueous solution. Static saturation adsorption required only 15 min to achieve equilibrium, with a binding capacity ( Q max ) of 44.5 μmol g −1 . The extraction of E2, ethinyl estradiol (EE), diethylstilbestrol (DES), ethisterone (ES) and estrone (E1) from water samples by MIHSs was also investigated. In the spiked samples of tap water, Qinghe river water and Zhanjiang river water, more than 90.42% of E2, but less than 79% of EE, DES, ES and E1 were recovered. The limits of detection (LOD) ranged from 0.1 to 0.26 µmol L −1 after solid phase extraction by MIHSs and HPLC–UV analysis. The adsorption capacity of the MIHSs showed no significant deterioration after six rounds of regeneration.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2010
·Vol. 118
·期 2
·678-684
·
IF 1.203
Xufei Liu,Jie Zhou,Changbao Chen
Using tribenuron-methyl as a template and N , O -bismethacryloyl ethanolamine as a functional crosslinking monomer, a molecularly imprinted nanowire membrane was prepared over an anodic alumina oxide membrane. The nanowire fabric of the imprinted membrane was established with a scanning electron microscope and a transmission electron microscope. However, the nonimprinted particulate membrane is formed in the absence of a template. Scatchard analysis showed that an equal class of binding sites were formed in the imprinted nanowire membrane and the dissociation constant and the maximum number of these binding sites were estimated to be 1.44 × 10 −5 M and 22.7 µmol/g, respectively. The permeation experiments throughout the imprinted membrane and the nonimprinted one were carried out in a solution containing the template and its competitive analogs. These results demonstrated that the molecularly imprinted nanowire membrane exhibited higher transport selectivity for the template tribenuron-methyl than its analogs, chlorimuron-ethyl, thifensulfuron-methyl and N -(4-bromophenylcarbamoyl)-5-chloro-1H-benzo[d]imidazole-2-carboxamide. But the nonimprinted granular membrane had no permselectivity for the four substrates. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Zheng-peng Yang,Xuan Liu,Chun-jing Zhang,Bao-zhong Liu
Transparent photocatalytic surfaces are of ever increasing importance for the enhancement of the photocatalytic efficiency. Here, the highly ordered transparent TiO 2 nanotube arrays were prepared by the anodization and thermal annealing of titanium layer deposited onto the glass substrate , and a novel nonenzymatic piezoelectric sensor was developed for urea detection based on the modification of molecularly imprinted TiO 2 thin film onto transparent TiO 2 nanotube arrays. The performance of the fabricated sensor was evaluated and the results indicated that the sensor exhibited high sensitivity in urea detection, with a linear range from 0.04 to 120 μM and a limit of detection of 0.01 μM. Moreover, the sensor presented outstanding selectivity while used in coexisting systems containing various interferents with high concentration. The analytical application of the urea sensor confirmed the feasibility of urea detection in urine sample.
研究领域:
生物传感技术
·
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Environments
·
2017
·Vol. 4
·期 2
·30
·
IF 0
Limei Huang,Yaqi Lu,Zhenyue Wu,Meishan Li,Shengchang Xiang,Xiuling Ma,Zhangjing Zhang
The environmental pollution of 2,4,6-tribromophenol (TBP) has attracted attention. Based on an urgent need for the better provision of clean water, in situ determination of TBP is of great importance. Here, a facile and effective approach for detecting TBP is developed, based on coupling molecular imprinting technique with electrodeposition of chitosan (CS) on the gold electrode. The TBP imprinting CS film was fabricated by using CS as functional material and TBP as template molecule. The experiments show that the morphologies and electrochemical properties of the imprinted film sensor was different from non-imprinted film electrode. The current of the imprinted film was linearly proportional to the TBP concentration, with a wide linear range of 1.0 × 10−7mol·L−1to 1.0 × 10−3mol·L−1. By selecting drop-coating method as a reference for controlled trials with the same functional material, the results illustrated that the electrodeposition enjoyed a widely linear range advantage.Keywords:2,4,6-tribromophenol;chitosan;molecular imprinting;electrodeposition
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
Polymers
·
2022
·Vol. 14
·期 19
·4133
·
IF 4.967
Lianming Zhang,Kui Luo,Jingxia Gao,Jianping Li
A new chiral molecularly imprinted polymer (MIP) sensor with dual recognition ability was developed for the highly selective separation of enantiomers with toxic side effects in drugs. The sensor contains double-stranded deoxyribonucleic acid (dsDNA) as the element that immobilizes the chiral molecular conformation: the dsDNA enables the imprinted cavities to match the three-dimensional structure and functional groups from the chiral molecule. By embedding the spatial orientation of dsDNA in MIPs, one can accurately capture and immobilize the molecular conformation, eliminating the influence of interfering analogues. Herein, L-penicillamine (L-Pen) was selected as the chiral template molecule and embedded into dsDNA to form dsDNA-L-Pen complex, which was then embedded into the MIPs by electropolymerization. After elution, the stereo-selective imprinted cavities were obtained. The ATATATATATAT-TATATATATATA base sequence showed a high affinity for the embedded L-Pen, which endowed the imprinted cavities with a larger number of sites and improved the selectivity toward Pen enantiomers. Under the optimal working conditions, the current response of the MIP/dsDNA sensor exhibited a positive linear relationship with the logarithm of the L-Pen concentration in the range of 3.0 × 10−16to 3.0 × 10−13mol/L, and the detection limit was 2.48 × 10−16mol/L. After the introduction of dsDNA into the MIP, the selectivity of the sensor toward D-Pen increased by 6.4 times, and the sensor was successfully applied in the analysis of L-Pen in penicillamine tablets.Keywords:molecularly imprint;sensor;dsDNA;chiral;L-Pen
研究领域:
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FIBERS AND POLYMERS
·
2016
·Vol. 17
·期 10
·1531-1539
·
IF 1.022
Mao Yanli,Cui Jiuyun,Zhao Juan,Wu Yilin,Wang Chen,Lu Jian,Lin Xinyu,Yan Yongsheng
Via Pickering emulsion polymerization, pH-sensitive magnetic molecularly imprinted polymers (HM-MIPs) were synthesized using bifenthrin (BF) as the template molecule, and pH-sensitive monomer methacrylic acid as the functional monomer. Characterizations of HM-MIPs were achieved by FTIR, TGA, TEM, SEM, and VSM, and the results indicated that HM-MIPs exhibited magnetic property (Ms=1.06 emu/g). HM-MIPs were acted as the adsorbent for a series of adsorption performance testing of BF. Equilibrium data were described by the Langmuir and Freundlich isotherm models. Kinetic properties were successfully investigated by pseudo-first-order model, pseudo-second-order model. The selective recognition experiments exhibited outstanding selectively adsorption effect of the HM-MIPs for target BF over diethyl phthalate and fenvalerate. In water, the HM-MIPs could achieve the adsorption and release of BF by controlling the pH value of the aqueous solution. The results indicated that the molecularly imprinted polymers exhibited good adsorption, selectivity and pH-sensitive performance for BF.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）