JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2016
·
IF 2.822
Fang Long,Jing Wang,Zhaohui Zhang,Liang Yan
A novel magnetic molecularly imprinted electrochemical sensor (MMIP-sensor) combined with magnetic molecularly imprinted solid-phase extraction (MMISPE) was constructed for rapid and sensitive detection of tetrabromobisphenol S (TBBPS) in water samples. The magnetic molecularly imprinted polymer based on magnetic graphene/multi-walled carbon nanotubes hybrid composite (MMIP/Gr-MWCNTs) was prepared as MMISPE sorbet to separate and enrich TBBPS from complex system. Adsorption results showed that the MMIP/Gr-MWCNTs possessed excellent selective adsorption toward TBBPS with a maximum adsorption capacity of 17.83 mg g − 1 . The magnetic imprinted sensor based on the magnetic Gr-MWCNTs composite modified electrode was prepared by electropolymerization of dopamine monomer . The high sensitivity of the MMIP-sensor was attributed to the large specific surface area and excellent electrical conductivity of the magnetic Gr-MWCNTs composites. The detection limit of the MIP-sensor toward TBBPS was calculated as 2.1 × 10 − 11 mol L − 1 (S/N = 3). Under the optimum conditions, the MISPE-MMIP-sensor combination system provided 10–12 fold preconcentration than that of MMIP-sensor alone determination. The MISPE-MMIP-sensor was successfully used for detection of TBBPS in drinking water , rain water , lake water and tap water with recoveries of 88.4–98.8%.
研究领域:
分析化学
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环境监测
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电化学传感
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分子印迹技术
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水处理
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污染物检测
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DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·Vol. 11
·期 8
·6466-6476
·
IF 1.5
Changling Yan,Jin Li,Tingting Meng,Xun Liu,Ruixing Zhang,Yujuan Chen,Gongke Wang
A simple and reliable method was proposed for rapid detecting ciprofloxacin, based on molecularly imprinted technology. The molecularly imprinted ciprofloxacin hydrochloride (CPX) sensor was prepared by electropolymerization of pyrrole (Py) and o-phenylenediamine (o-PD) on the pencil graphite electrode (PGE). The performance of the sensor was characterized by square wave voltammetry (SWV) using potassium ferricyanide as molecular probe. Under optimal conditions, the sensor displayed high selectivity and stability towards CPX. A linear relationship between the change in current (Δi) and the logarithm of CPX concentrations from 1×10 −9 to 1×10 −3 mol/L was obtained with a detection limit of 7.58×10 −11 mol/L (S/N=3). Furthermore, the MIP sensor was applied for the analysis of real tablet samples with high accuracies.
研究领域:
分析化学
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药物分析
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电化学传感
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分子印迹技术
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药物残留检测
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DOI
高影响因子
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
·
2022
·
IF 2.942
Dadong Liang,Xiaoshuang Wang,Jin Liu,Junbo Liu,Shanshan Tang,Bao Xu,Ruifa Jin
Here, norfloxacin (NOR) molecularly imprinted polymers (MIPs) exhibiting improved adsorption and selectivity properties were prepared via simulation and experiment. NOR and methacrylic acid (MAA) were employed as the imprinting molecule and functional monomer , respectively. The imprinting ratio, as well as cross-linking agents of the NOR–MIPs, had been optimised via the LC-ωPBE/6-31G( d , p ) method. The nature and mechanism of the interaction between MIPs and MAA, as well as the selectivity of the NOR–MAA stable complex (1:1), were also discussed. Based on the simulation results, the effects of the different imprinting ratios and cross-linking agents on the adsorption of NOR–MIPs were also investigated. Concurrently, the affinity, selectivity and stability of NOR–MIPs were analysed via dynamic, static and selective adsorption, as well as thermogravimetry . The calculated and experimental results demonstrated that the stable complexes comprising NOR and MAA were formed via hydrogen bonding . The complex comprising NOR and MAA in an interaction ratio of 1:6 exhibited the highest number of hydrogen bonds and the lowest binding energy. Trihydroxymethylpropyl trimethylacrylate was more appropriate for the synthesis of NOR–MIPs compared with the two other cross-linking agents. NOR–MIPs achieved the excellent selective adsorption of NOR in single and multiple adsorption systems. This design and synthesis strategy availed a new idea for the efficient preparation of s with specific adsorption performance.
研究领域:
材料科学
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高分子化学
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环境化学
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分析化学
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分子印迹技术
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2014
·
IF 3.583
Haiyun Zhai,Jiangmei Li,Zuanguang Chen,Zihao Su,Zhenping Liu,Xiao Yu
A simple glass/PDMS microfluidic chip for on-line sample pretreatment and contactless conductivity detection, which consisted of a 0.17 mm-thick glass cover and a PDMS substrate embedded with an SPE monolithic column, was presented in this paper. Using this integrated microchip system, sample extraction, injection, separation and detection were automatically performed in sequence. A sample of auramine O was concentrated by molecularly imprinted SPE (MISPE), eluted to sample reservoir, and injected by electromigration into separation channel for electrophoresis separation and contactless conductivity detection, with the calculated detection limit (S/N = 3) being 2.5 μg mL − 1 . The monolithic column was utilized to quantitatively extract auramine O , yielding an on-line enrichment factor of about 12. The microchip system is reliable and applicable to the analysis of auramine O in food sample.
研究领域:
分析化学
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微流控技术
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食品安全
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分子印迹技术
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电泳学
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生物医学工程
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DOI
高影响因子
MARINE POLLUTION BULLETIN
·
2015
·Vol. 102
·期 1
·142-147
·
IF 2.991
Xiuping He,Xiaoqi Mei,Jiangtao Wang,Ziru Lian,Liju Tan,Wei Wu
An effective and highly selective molecularly imprinted material was prepared by suspension polymerization for the isolation and pre-concentration of synthetic estrogen diethylstilbestrol (DES) in seawater . The obtained MIPMs were proved to have more uniform size and porous structure, with maximum adsorption capacity of 8.43 mg g − 1 almost two times more than NIPMs (4.43 mg g − 1 ). The MIPMs showed no significant deterioration of the adsorption capacity after five rounds of regeneration. An off-line molecularly imprinted solid phase extraction (MISPE) method followed by HPLC–DAD was proposed for the detection of DES in seawater , and recoveries were satisfactorily higher than 77%. Four seawater samples in aquaculture area were analyzed and 0.61 ng mL − 1 DES was detected in one sample. The result demonstrated that this method can be used for the rapid separation and clean up of trace residual of DES in seawater.
研究领域:
环境分析化学
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海洋环境污染
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分子印迹技术
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药物残留检测
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水体污染物
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2016
·
IF 7.476
Ni Xiao,Jian Deng,Jianlin Cheng,Saiqin Ju,Haiqing Zhao,Jin Xie,Duo Qian,Jun He
A novel electrochemical sensor based on duplex molecularly imprinted polymer (DMIP) hybrid film modified carbon paste electrode (CPE) has been developed for highly sensitive and selective determination of metronidazole (MNZ). A conductive poly(anilinomethyltriethoxysilane) film is firstly electrodeposited on the surface of a CPE, and then a molecularly imprinted polysiloxane (MIPS) membrane is covalently covered on the film via sol-gel process. The as-constructed DMIP hybrid film, combining the advantages of MIPS and conducting MIP, can make feasible the direct and efficient signal transformation between the target analyte and the transducer, as well as enhance the imprinting recognition capability, mass transfer efficiency and the detection sensitivity. Under optimized conditions, the reduction peak currents of MNZ are linear to MNZ concentrations in the range from 4.0×10 −7 to 2.0×10 −4 mol L −1 with a detection limit of 9.1×10 −8 mol L −1 . The RSD values vary from 2.9% to 4.7% for intra-day and from 3.4% to 4.2% for inter-day precision. The DMIP-based sensor has been successfully applied for the determination of MNZ in biological and pharmaceutical samples. The accuracy and reliability of the method is further confirmed by high performance liquid chromatography .
研究领域:
电分析化学
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传感器与生物传感器
·
环境与药物分析
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材料科学
·
分子印迹技术
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DOI
高影响因子
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