JOURNAL OF MEMBRANE SCIENCE
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2021
·
IF 8.742
Junhui Zhao,Xinda You,Guangzhe Wang,Jinqiu Yuan,Yafei Li,Chao Yang,Shiyu Zhang,Xiaoyao Wang,Runnan Zhang,Hong Wu,Zhongyi Jiang
Nanofiltration membranes that can selectively remove multivalent ions from salty water hold great promise in water treatment and salt utilization. However, developing nanofiltration membranes with high rejection to both divalent anions and cations remains a grand challenge. Herein, we design a kind of mix-charged polyamide membranes (MCPMs) via molecular hybridization to achieve the removal of versatile divalent ions. Amino-functionalized polyhedral oligomeric silsesquioxane (NH 2 -POSS) was employed as molecular filler added into piperazine and reacted with trimesoyl chloride at the aqueous-organic interface to generate cross-linked polyamide-NH 2 -POSS mixed network. The protonated amino groups from NH 2 -POSS offered positively charged sites for enhanced divalent cation repulsion while the deprotonated carboxyl groups from polyamide network can afford negatively charged sites for divalent anion repulsion. The optimized membrane displayed high rejections to both divalent anionic and cationic ions (Na 2 SO 4 rejection of 98.2%, MgCl 2 rejection of 98.0%), together with high mono-/divalent salt selectivity (NaCl/Na 2 SO 4 of 48.2, LiCl/MgCl 2 of 43.9) that outperformed the benchmark nanofiltration membranes. This molecularly-hybridized charge modulation method may enlighten the structural design of membranes for efficient ionic separations.
研究领域:
材料科学
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环境工程
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膜技术
✓ 已验证
产品关联
DOI
高影响因子
NATURE
·
2024
·
IF 50.5
Liu Sanwan,Li Jingbai,Xiao Wenshan,Chen Rui,Sun Zhenxing,Zhang Yong,Lei Xia,Hu Shuaifeng,Kober-Czerny Manuel,Wang Jianan,Ren Fumeng,Zhou Qisen,Raza Hasan,Gao You,Ji Yitong,Li Sibo,Li Huan,Qiu Longbin,Huang Wenchao,Zhao Yan,Xu Baomin,Liu Zonghao,Snaith Henry J.,Park Nam-Gyu,Chen Wei
Perovskite solar cells (PSCs) with an “inverted” architecture are a key pathway for commercializing this emerging photovoltaic technology due to the better power conversion efficiency (PCE) and operational stability as compared to the “normal” device structure. Specifically, PCEs of the inverted PSCs have exceeded 25% owing to the development of improved self-assembled molecules (SAMs) 1-5 and passivation strategies 6-8 . Nevertheless, poor wettability and agglomerations of SAMs 9-12 will cause interfacial losses, impeding further improvement in PCE and stability. Herein, we report on molecular hybrid at the buried interface in inverted PSCs by co-assembling a multiple carboxylic acid functionalized aromatic compound of 4,4’,4’’-nitrilotribenzoicacid (NA) with a popular SAM of [4-(3,6-dime-thyl-9H-carbazol-9-yl)butyl]phosphonic acid (Me-4PACz) to improve the heterojunction interface. The molecular hybrid of Me-4PACz with NA could substantially improve the interfacial characteristics. The resulting inverted PSCs demonstrated a record-certified steady-state efficiency of 26.54%. Crucially, this strategy aligns seamlessly with large-scale manufacturing, achieving the highest certified PCE for inverted mini-modules at 22.74% (aperture area: 11.1 cm 2 ). Our device also maintained 96.1% of its initial PCE after more than 2,400 hours of 1-sun operation in ambient air.
研究领域:
材料科学
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光伏技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
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2014
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IF 5.9
Jing Yu,Wei Ha,Jian-nan Sun,Yan-ping Shi
In this work, we developed a simple, novel method for constructing gold nanocomposite supramolecular hybrid hydrogels for drug delivery, in which gold nanocrystals were utilized as building blocks. First, methoxypoly(ethylene glycol) thiol (mPEG-SH, molecular weight (MW) = 5 K) capped gold nanocrystals (nanospheres and nanorods) were prepared via a facile one-step ligand-exchange procedure. Then, the homogeneous supramolecular hybrid hydrogels were formed, after adding α-cyclodextrin (α-CD) into PEG-modified gold nanocrystal solutions, due to the host–guest inclusion. Both gold nanoparticles and inclusion complexes formed between α-CD and PEG chain provided the supra-cross-links, which are beneficial to the gelation formation. The resulting hybrid hydrogels were fully characterized by a combination of techniques including X-ray diffraction, rheology studies, and scanning electron microscopy. Meanwhile, the hybrid hydrogel systems demonstrated unique reversible gel–sol transition properties at a certain temperature caused by the temperature-responsive reversible supramolecular assembly. The drug delivery applications of such hybrid hydrogels were further investigated in which doxorubicin was selected as a model drug for in vitro release, cytotoxicity, and intracellular release studies. We believe that the development of such hybrid hydrogels will provide new and therapeutically useful means for medical applications.
研究领域:
材料科学
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生物医学工程
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药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Biomedical Nanotechnology
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2018
·Vol. 14
·期 12
·2056-2065
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IF 5.068
Zhang Qian,Deng Hua,Li Hanjun,Song Keyi,Zeng Cheng,Rong Ling
Graphene oxide (GO) has attracted a wide attention for its excellent mechanical, thermal properties and unique two-dimensional structure. In this work, A new GO-based supramolecular hybrid nanohydrogel was prepared, in which GO as the cross-links was incorporated into the above hydrogel
through non-covalent functionalization to enhance the mechanical properties and control morphology. A 1-pyrenebutyric acid (Py) modified low-molecular weight (MW) mPEG was firstly synthesized via a simple esterification reaction. Then, low-MW mPEG functionalized GO (GO-Py-PEG) was obtained
due to the strong π–π stacking interaction between Py and GO. The combination of the host-guest interaction between mPEG and -CD and addition of GO lastly leaded to the formation of supramolecular hybrid nanohydrogel. Various techniques including UV-vis spectroscopy,
Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA) and transmission electron microscopy (TEM) were used to thoroughly characterize the hybrid hydrogel. More interestingly, the results of rheology studies and scanning electron microscopy
(SEM) revealed that the mechanical strength and morphology of hybrid hydrogel was improved by the incorporation of GO. Meanwhile, doxorubicin hydrochloride (DOX) as a model drug was loaded into hybrid hydrogel, and the in vitro released behavior was studied under different pH values.
The results showed that the formed hybrid hydrogel could release DOX over 50 h in a sustained manner. In addition, in vitro and in vivo experiments, GO-Py-PEG-α-CD@DOX hydrogel (hydrogel@DOX) dramatically shows the inhibition of tumor cell proliferation and tumor
growth. At the same time, HE staining results show hydrogel@DOX can significantly reduce the side effects of DOX. We believe that the development of such hybrid hydrogels will provide important potential for medical applications.
研究领域:
材料科学
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生物医学工程
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药学
✓ 已验证
DOI
PubMed
高影响因子
SYNTHETIC COMMUNICATIONS
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2019
·
IF 1.439
Shuang Chen,Jing Yue,Xiong-Li Liu,Jun-Xin Wang,Xiong Zuo,Yu Cao
A new method was developed for the facile one-pot multicomponent construction of heterocycle-fused spiro compounds containing chromanone and pyrrolidinyl spirooxindoles, two potential pharmacophores, in one molecule through a decarboxylative 1,3-dipolar [3 + 2] cycloaddition reaction of carboxylic acid group-activated chromones 1 with isatin-derivated azomethine ylides based on molecular hybridization strategy. A wide variety of products with three contiguous stereocenters including a spiro quaternary stereocenter were smoothly prepared with high efficiency (up to 87% yield and 20:1 diastereomeric ratio). This method could offer libraries of architecturally diverse and multiple pharmacore collections, potentially useful in medicinal chemistry.
研究领域:
有机化学
·
药物化学
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合成化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）