ENERGY & FUELS
·
2016
·
IF 2.835
Shurong Wang,Yurong Wang,Furong Leng,Junhao Chen
Sugars are among the main compounds in bio-oil produced by biomass pyrolysis. However, they can easily form coke, resulting in fast deactivation of the catalyst and severe blockage of the reactor during catalytic upgrading of bio-oil. Molecular distillation may be performed to retain sugars and pyrolytic lignin in the heavy fraction and thus to provide a primary stage for the subsequent sugar separation and utilization. A new method involving extraction, heat treatment, and column chromatography was introduced to separate further the aqueous phase obtained from the bio-oil heavy fraction by methanol–water extraction. Thus, monophenols and sugars were coextracted through these combined separation technologies. A fraction rich in monophenols was obtained by solvent extraction. Other impurities were further removed by heat treatment and column chromatography. An alcohol sedimentation method further separated the combined sugar-rich fraction into an ethanol-soluble fraction (SF-1) and an ethanol-insoluble fraction (SF-2). Gas chromatography–mass spectrometry, Fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and high-performance liquid chromatography were performed to characterize sugars in the obtained fractions. SF-1 mainly contained monosaccharides such as levoglucosan, glucose, and xylose, whereas SF-2 still had a small amount of cellobiose besides monosaccharides. The ultimate recovery rates for several identified monosaccharides were in the range of 75–86 wt %.
研究领域:
能源与环境科学
·
化学工程
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Wenhao Deng,Yuehua Deng,Wang Zhao,Rui Zhang,Yanbin Jiang
Tetramethylammonium hydroxide pentahydrate (TMAH·5H 2 O) is easily decomposed when heated, which results in the difficulty of dehydration. In this study, a new process for dehydration of a TMAH propylene glycol solution using wiped-film molecular distillation was developed. The experiments were carried out to evaluate the effect of operating conditions on the performance of the dehydration with the operating temperature ranging from 65 °C to 90 °C, the operating pressure from 100 Pa to 2000 Pa and the mass flow rate from 36 to 162 g/min. The experimental results indicated that molecular distillation was capable of dehydrating TMAH solution to a water content of 0.65% from 5.82%. Then a modified Flash module in Aspen plus, which used the fitting factor and linear correlation between the simulated and experimental temperatures, was developed to simulate the dehydration process. The relative error between the modified simulated and experimental data is less than 5%, and the response surface methodology analysis was conducted to optimize the operating conditions. The optimal dehydration conditions were 85 °C, 100 Pa and 54 g/min feed flow rate, where the minimum water content in distilled solution is 0.43%. The results show that the process developed realizes a high efficiency of dehydration and prevents TMAH from thermal decomposition.
研究领域:
化学工程
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材料科学
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产品关联
DOI
高影响因子
Food Science & Nutrition
·
2018
·Vol. 6
·期 6
·1431-1437
·
IF 1.521
Qingyun Guo,Ke Liu,Weihui Deng,Balian Zhong,Wenxia Yang,Jiong Chun
The present investigation reported the chemical composition of cold pressed Gannan navel orange peel essential oil (EO) and its molecular distillation fraction (light phase EO), and examined their antimicrobial activity against spoiling and pathogenic microorganisms. Gas chromatography-mass spectrometry analysis identified 27 and 20 different chemical constituents in cold pressed EO and light phase EO, respectively. Limonene was the major constituent, accounting for 85.32% of cold pressed EO and 60.44% of light phase EO. Both EOs and some of their constituents showed good antimicrobial activity. Compared to cold pressed EO, light phase EO exhibited the better antimicrobial activity under weak acidic and neutral conditions. The light phase EO presented a higher antimicrobial activity after thermo-treatment at 60–100°C for 20 min than cold pressed EO. These results demonstrated that light phase EO had a potential to be used as a novel antimicrobial agent for food preservation and food processing.
研究领域:
食品科学
·
植物化学
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产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2022
·
IF 3.898
Yingxi Gao,Jiayi Shi,Jie Wang,Fan Zhang,Shichao Tian,Zhiyong Zhou,Zhongqi Ren
Nervonic acid is the world's first and only potent substance that can repair damaged nerve fibers and promote nerve cell regeneration with high nutritional value. The wide variety of fatty acids in plant oils and fats with similar structures makes the large-scale separation and purification of high-purity nervonic acid very difficult. A new combined process of molecular distillation, urea inclusion and solvent crystallization was established to prepare high-purity nervonic acid with the mixed fatty acids obtained after saponification and acidification of Acer truncatum Bunge oil as raw materials. First, according to the difference in the mean free path of fatty acids, molecular distillation was used to separate and remove C16 saturated fatty acid of palmitic acid and four C18–C20 fatty acids of stearic, oleic, linoleic, and linolenic acids. The content of C16–C20 fatty acids decreased from 72.92% to 19.22% after two-stage molecular distillation processes, in which the contents of saturated fatty acid of palmitic acid decreased to about 0.5%. Then, according to the difference in carbon chain length and saturation of fatty acid, the contents of C22–C24 saturated fatty acids of tetracosanoic and docosanoic acids decreased to 0.21% and 0.07% by urea inclusion with urea/free fatty acid preparation by saponification (SPOMFs) ratio as 0.6. In addition, all saturated fatty acids were basically separated. Finally, according to the difference in the solubility of fatty acids in solvents, the C18–C20 unsaturated fatty acids of oleic, linoleic, and linolenic acids and C22 unsaturated fatty acid of erucic acid were removed by solvent crystallization. The content of C18–C20 unsaturated fatty acids decreased to less than 5% with pentanol as the solvent after the first stage solvent crystallization. The content of erucic acid decreased to 3.47% with anhydrous ethanol as the solvent after the second to fifth stage solvent crystallization. The combined process of molecular distillation, urea inclusion and low temperature crystallization innovatively adopted an efficient, simple and easy-to-industrial solvent crystallization method to separate erucic and nervonic acids, obtaining nervonic acid with purity of 96.53% and final yield of 47.99%.
研究领域:
食品科学
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生物化学
✓ 已验证
产品关联
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2019
·
IF 3.714
Dan Zhou,Qinlong Shi,Jiangbo Pan,Min Liu,Yi Long,Fahuan Ge
ion In this study, the combination of supercritical fluid extraction and molecular distillation (SFE-MD) was used to improve the quality of camellia oil. A series of important process parameters were investigated to obtain high quality camellia oil. Compared with the camellia oil produced by supercritical fluid extraction (SFE), the acid value of camellia oil obtained by SFE-MD was significantly decreased to 0.63 ± 0.01 from 2.93 ± 0.01 mg KOH/g oil, without any change of their fatty acid compositions. Furthermore, unsaponifiable matters of camellia oil such as γ-tocopherol, β-sitosterol and squalene could be effectively preserved and there were no residual harmful substances. The technology provided in this study is effective, economical and environment-friendly and could be replicated in an industrial scale.
研究领域:
食品科学
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化学工程
·
植物提取
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION SCIENCE AND TECHNOLOGY
·
2021
·
IF 2.475
Jia-Lun Zhong,Nadeem Muhammad,Shun-Quan Chen,Li-Wei Guo,Jia-Sheng Li
The essential oils of Artemisia argyi Lévl. et Vant were extracted and separated using three methods, hydrodistillation (HD), supercritical fluid extraction (SFE), and SFE coupled molecular distillation (SFE-MD). Various extraction parameters of SFE were optimized by process modeling of Hansen solubility parameters which are 30 MPa, temperature 45°C, no co-solvents, extraction time 2 h, and flow rate of 90 kg/h. The essential oils obtained by HD and SFE-MD have similar major compositions. The antimicrobial activities were examined according to the agar well diffusion method and the minimum inhibition concentrations against Staphylococcus aureus and Escherichia coli were compared.Abbreviations A. argyi, Artemisia argyi; CFU, Colony Forming Unit; DMSO, dimethylsulfoxide; E. coli, Escherichia coli; GC-MS, Gas Chromatography-Mass Spectrometer; HD, hydrodistillation; HSP, Hansen solubility parameters; MIC, minimum inhibition concentration; OSE, organic solvents extraction; RSM, response surface methodology; SCCO2, supercritical-CO2; SFE, supercritical fluid extraction; SFE-MD, SFE coupled molecular distillation; SMILES, Simplified Molecular Input Line Entry Syntax; S. aureus, Staphylococcus aureus;
研究领域:
植物化学
·
分离技术
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药用植物研究
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产品关联
DOI
高影响因子
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
·
2020
·
IF 1.992
Song Zhang,Jian Xiong,Wenyong Lou,Zhengxiang Ning,Denghui Zhang,Jiguo Yang
This study was designed to synthesize triglycerol monolaurate (TGML) with Lipozyme 435 as the catalyst, and explore its effects on the growth of Aspergillus parasiticus ( A. parasiticus ) and Aspergillus flavus ( A. flavus ) and the secretion of aflatoxin b1. The highest content of TGML (49.76%) was obtained at a molar ratio of triglycerol to lauric acid of 1.08, a reaction temperature of 84.93°C, a reaction time of 6 h and an enzyme dosage of 1.32%. After purification by molecular distillation combined with the washes with ethyl acetate and water, the purity of TGML reached 98.3%. Through characterization by electrospray-ionization mass spectrometry, infrared spectrum and nuclear magnetic resonance, the structure of TGML was identified as a linear triglycerol combined with lauroyl at the end. Finally, the inhibitory effects of TGML on the growths of A. parasiticus and A. flavus and the secretion of aflatoxin b1 were evaluated by measuring the colony diameter, the inhibition rate of mycelial growth and the content of mycotoxin in the media. The results indicated that TGML had a stronger inhibitory effects on colony growth and mycelial development of both toxic molds compared to sodium benzoate and potassium sorbate, and the secretions of toxins from A. parasiticus and A. flavus were completely suppressed when adding TGML at 10 and 5 mM, respectively. Based on the above results, TGML may be used as a substitute for traditional antifungal agents in the food industry.
研究领域:
食品科学
·
微生物学
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DOI
PubMed
高影响因子
ACS Omega
·
2021
·
IF 3.512
Wen Lv,Chunjian Wu,Sen Lin,Xuping Wang,Yonghua Wang
Soybean oil deodorizer distillate (SODD) is well recognized as a good source of both biodiesel and high-value bioactive compounds of tocopherols, squalene, and phytosterols. To achieve a one-step synthesis of biodiesel and recovery of bioactive compounds from SODD, four commercial immobilized enzymes (Novozym 435, Lipozyme TLIM, Lipozyme RMIM, and Lipozyme RM) and one self-prepared immobilized lipase MAS1-H108A were compared. The results showed that immobilized lipase MAS1-H108A due to the better methanol tolerance and higher catalytic activity gave the highest biodiesel yield of 97.08% under the optimized conditions: molar ratio of 1:2 (oil/methanol), temperature of 35 °C, and enzyme loading of 35 U/g SODD, even after 10 persistent cycles without significant decrease of activity. Simultaneously, there was no loss of tocopherols and squalene in SODD during the enzymatic reaction. Pure biodiesel (characterized by fourier transform infrared (FT-IR) and nuclear magnetic resonance (NMR)) and a high concentration of bioactive compounds could be successfully separated by molecular distillation at 100 °C. In a word, this work provides an interesting idea to achieve environmentally friendly treatment of SODD by combining an enzymatic process and molecular distillation, and it is suitable for industrial production.
研究领域:
生物化学
·
可再生资源与环境工程
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DOI
PubMed
高影响因子
JOURNAL OF FOOD SCIENCE
·
2024
·
IF 3.2
Longfei Liu,Hongling Cai,Youfeng Zhang,Qingzhe Jin,Xingguo Wang,Jun Jin
Walnut oils are of important academic and economic value, and are becoming one of the most important woody oils. Accurate and moderate refining techniques are required to produce high-quality walnut oils. In this work, walnut oils obtained from cold processing were refined in three typical techniques, mainly chemical refining, water degumming, and molecular distillation. Physicochemical properties (acid value and peroxide value [POV]), minor components (tocopherol, polyphenols, and phytosterol), oxidative stability indices, and volatile compounds were analyzed to find out the appropriate refining method for the cold-pressed walnut oils. Quality indices of all the refined oils from the three different refining methods met the requirements of the national standard, of which the POV of chemically refined oil (0.241 g/100 g) was higher than crude oil (0.058 g/100 g). Water degumming was most suitable for retaining of bioactive compounds, for example, the tocopherol was 259.40 mg/kg, the polyphenols was 44.54 mg GAE/kg, and the phytosterol was 987.32 mg/kg, but oxidation stability of the obtained oil (3.09 h) was lower than that of molecular distilled oil (4.18 h). Initial physicochemical properties especially the POV had a significant impact on oxidation stability. There is a trade-off between the retention of nutrients and extending shelf life, indicating appropriate refining techniques should be developed; that is, water degumming is suggested to be involved in producing high-quality cold-pressed walnut oils.
研究领域:
食品科学
·
油脂化学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROCESS BIOCHEMISTRY
·
2020
·
IF 2.952
Chang-Wei Zhang,Ming-Fei Li,Zhi-Wen Qi,Ran Tao,Jian-Zhong Ye,Xing-Ying Xue,Cheng-Zhang Wang
The aim of this work was to construct a new type of system for the green extraction and efficient separation of Ginkgo biloba leaf polyprenols (GBP). First, cell disruption technologies (enzymolysis, ultrasound, microwave and ball milling) coupled with deep eutectic solvents (DES) were used to extract polyprenyl acetates (PA) from Ginkgo biloba leaves. Results showed that ball milling was the best assisted extraction method, and the amount of PA was 89.88 mg/g. Then, a novel silver-loaded material with selectivity for PA was synthesized, characterized and utilized to absorb PA from the DES extraction solution. The purity of the PA quickly reached 71.28 % after being separated by the silver-loaded material. Finally, saponification and molecular distillation were adopted to remove non-GBP ingredients, and a high-purity GBP (99.80 %) was obtained by optimizing its processing conditions. This study provides a technical support for the development of a green and efficient GBP separation method and lays the foundation for the fabrication of GBP-based drugs, health products and cosmetics.
研究领域:
天然产物化学
·
药物分离与纯化
·
绿色化学
·
植物化学
·
分析化学
✓ 已验证
DOI
高影响因子
Frontiers in Pharmacology
·
2023
·
IF 5.6
Liu Yang,Wang Fang,Guo HuiWen,Zhang Dingkun,Zhang Xiaofei,Wu Zhenfeng,Li Huiting,Xian Yang,Yue Pengfei,Yang Ming
Asarum essential oil (AEO) has been shown to have good pharmacological activities for the anti-inflammatory and analgesic effects, but increasing the dose may cause toxicity. Therefore, we studied the toxic and pharmacodynamic components of AEO by molecular distillation (MD). Anti-inflammatory activity was assessed using RAW264.7 cells. Neurotoxicity was assessed in PC12 cells and the overall toxicity of AEO was evaluated in the mouse acute toxicity assay. The results showed that AEO is primarily composed of safrole, methyl eugenol, and 3,5-dimethoxytoluene. After MD, three fractions were obtained and contained different proportions of volatile compounds relative to the original oil. The heavy fraction had high concentrations of safrole and methyl eugenol, while the light fraction contained high concentrations of α-pinene and β- pinene. The original oil and all three fractions exhibited anti-inflammatory effects, but the light fraction demonstrated more excellent anti-inflammatory activity than the other fractions. Asarum virgin oil and MD products are all neurotoxic. The exposure of PC12 cells to high concentrations of AEO resulted in abnormal nuclei, an increased number of apoptotic cells, increased ROS formation, and decreased SOD levels. Moreover, the results of acute toxicity tests in mice revealed that the light fractions were less toxic than virgin oils and other fractions. In summary, the data suggest that the MD technology enables the enrichment and separation of essential oil components and contributes to the selection of safe concentrations of AEO.
研究领域:
药理学
·
毒理学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）