RSC Advances
·
2019
·Vol. 9
·期 59
·34652-34657
·
IF 3.049
Shengling Li,Duanlin Cao,Zhiyong Hu,Zhichun Li,Xianjiao Meng,Xinghua Han,Wenbing Ma
In this study, a highly selective chemosensor ML based on a BODIPY fluorescent chromophore was synthesized for sequential recognition of Cu2+ and HSO3− in a CH3OH/H2O (99 : 1 v/v) system, which contained three recognition sites and its structure characterized by 1H NMR, 13C NMR and ESI-HR-MS. The sensor ML showed an obvious “on–off” fluorescence quenching response toward Cu2+ and the ML-Cu2+ complex showed an “off–on” fluorescence enhancement response toward HSO3−. The detection limit of the sensor ML was 0.36 μM to Cu2+ and 1.4 μM to HSO3−. In addition, the sensor ML showed a 1 : 3 binding stoichiometry to Cu2+ and the recovery rate of ML-Cu2+ complex identifying HSO3− could be over 70%. Sensor ML showed remarkable detection ability in a pH range of 4–8.
研究领域:
分析化学
·
生物化学
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DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Xian Zhou,Wenjing Cheng,Fudan Zhu,Cunli Wang,Fengchun Yang,Weidong Kang,Xin Zhang
As an herbicide, oryzalin (ORZ) is extensively used to control the growth of weeds, whereas excessive ORZ is harmful to human beings. Therefore, it is imperative for its quantitative detection. However, numerous efforts have been focused on noble-metal materials in electrochemical sensing, increasing the application cost. In this study, CoMoS/O-MWNTs hybrid with wrinkled nanosheets , as a non-noble metal electrocatalyst , is successfully synthesized by hydrothermal method . The CoMoS/O-MWNTs is cost-effective and has the elevated stability and catalytical activity, which can be attributed to the combination between CoMoS and O-MWNTs through O element strengthens strong coupling interaction of Co Mo. The platform possesses the wide linear detecting range of 0.48–22 μM and 22–85 μM, which is wider than previous reports. Thus, the excellent electrochemical property demonstrates CoMoS/O-MWNTs is an effective electrocatalyst for the reduction of ORZ.
研究领域:
电化学
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纳米材料
·
环境监测
·
传感器技术
·
农业化学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2011
·Vol. 16
·期 4
·1635-1642
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IF 2.234
Ye Daixin,Xu Yanhong,Luo Liqiang,Ding Yaping,Wang Yulong,Liu Xiaojuan
A novel electrochemical sensor based on LaNi 0.5 Ti 0.5 O 3 /CoFe 2 O 4 nanoparticle-modified electrode (LNT–CFO/GCE) for sensitive determination of paracetamol (PAR) was presented. Experimental conditions such as the concentration of LNT–CFO, pH value, and applied potential were investigated. Under the optimum conditions, the electrochemical performances of LNT–CFO/GCE have been researched on the oxidation of PAR. The electrochemical behaviors of PAR on LNT–CFO/GCE were investigated by cyclic voltammetry. The results showed that LNT–CFO/GCE exhibited excellent promotion to the oxidation of PAR. The over-potential of PAR decreased significantly on the modified electrode compared with that on bare GCE. Furthermore, the sensor exhibits good reproducibility, stability, and selectivity in PAR determination. Linear response was obtained in the range of 0.5 to 901 μM with a detection limit of 0.19 μM for PAR.
研究领域:
生物医学工程
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药物分析
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电化学检测
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2018
·
IF 8.173
M.Z.H. Khan,Xiaoqiang Liu,J. Zhu,F. Ma,W. Hu,Xiuhua Liu
This work reports the development of a simple and cost-effective electrochemical sensor based on electrochemically reduced graphene oxide (ErGO) bound to the surface of indium tin oxide (ITO) electrode through 3-aminopropyltriethoxysilane (APTES) monolayer (ITO/APTES/ErGO) for selective and sensitive detection of tyramine . The features of the modified electrode were studied by scanning electron microscopy (SEM), cyclic voltammetry (CV), and electrochemical impedance (EIS) methods. The analytical performance of the developed sensor was evaluated with respect to linear detection range, limit of detection, stability, coexistence interference and reproducibility. The modified device exhibited electrocatalytic activity toward tyramine oxidation within two linear concentration range of 1–100 nM, and 1–100 µM, with LOD of 0.1 nM. Finally, the sensor successfully detected tyramine in commercially available real samples with satisfactory recovery ranges. The proposed modified sensor offers distinct advantages including low cost, simple handling, good sensitivity and high selectivity.
研究领域:
分析化学
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生物医学工程
·
电化学
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Quan Xu,Shuxian Chen,Jingkun Xu,Xuemin Duan,Limin Lu,Qingyun Tian,Xinxin Zhang,Yue Cai,Xinyu Lu,Liangmei Rao,Yongfang Yu
Luteolin (LUT) is one of the biologically active functional components, which was widely used in pharmacological applications. Thus, development of sensitive analytical methods for LUT determination is highly desired. In this work, Ti 3 C 2 -MXene/ZIF-67/CNTs heterostructure was exploited as a new electrochemical sensing platform for the sensitive determination of LUT. For the design of composite, the in-situ growth of ZIF-67 on CNTs surface ensures the stability of their binding and enhances the synergetic catalysis. Conductive MXene as matrix for the loading of ZIF-67/CNTs can promote the catalytic ability of composite. Electrochemical results show that the MXene/ZIF-67/CNTs modified electrode displays preeminent electrocatalytic activity and enhances electrochemical response to the redox reaction of LUT, ascribing to the synergistic effect of ZIF-67/CNTs and MXene. Upon the optimization of experimental parameters, e.g., pH, enrichment time, the sensor based on MXene/ZIF-67/CNTs composite exhibits excellent performance with wide linear relationship ranging from 0.1–1000 nM and a low limit of detection (LOD) of 0.03 nM (S/N = 3). Besides, MXene/ZIF-67/CNTs electrode performs high selectivity, stability, and acceptable reproducibility. Furthermore, the constructed sensor was successfully utilized to detect LUT in real samples with satisfactory recovery.
研究领域:
分析化学
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纳米生物技术
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电分析化学
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药物分析
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功能材料
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 3
·1-11
·
IF 5.3
Liu Huamin,Li Chenghong,Wang Lina,Fang Lichao,Huang Hui,Deng Jun,Hu Yue,Li Mimi,Ran Xiaoping,Li Lulu,Zheng Junsong
A “signal-off” photoelectrochemical (PEC) sensing platform has been designed for the ultrasensitive detection of DNA methylation levels and multiple methylated sites. The platform employs tungsten trioxide and TpPa-1-COF loaded by gold nanoparticle (AuNPs@WO 3 @TpPa-1-COF) composite material as the photoactive component and p-type reduced graphene (rGO) as an efficient quencher. The PEC signal of AuNPs@WO 3 @TpPa-1-COF composite is effectively quenched in the presence of p-type rGO, because p-type rGO can compete with AuNPs@WO 3 @TpPa-1-COF to deplete light energy and electron donors. In addition, a hybrid strand reaction (HCR) amplification strategy fixes more target DNA and then combines with rGO-modified anti-5-methylcytosine antibody to facilitate ultrasensitive DNA methylation detection. Under optimal conditions, DNA methylation can be measured within a linear concentration range of 10 –14 to 10 –8 M, with an exceptionally low detection limit of 0.19 fM (S/N = 3). At the same time, the platform can conduct quantitative determination of multi-site methylation, with the linear equation △I = 44.19Log A + 61.43, and the maximum number of methylation sites is 5. The sensor demonstrates high sensitivity, excellent selectivity, and satisfactory stability. Furthermore, the proposed signal-off PEC strategy was successfully employed to detect DNA methylation in spiked human serum samples, with recoveries ranging from 93.17 to 107.28% and relative standard deviation (RSD) ranging from 1.15 to 5.49%. Graphical
研究领域:
生物化学
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分析化学
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材料科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2014
·Vol. 18
·期 9
·2487-2496
·
IF 2.234
Wang Zhihua,Li Jinshu,Xu Lijuan,Feng Yanjun,Lu Xiaoquan
A sensitive and selective imprinted electrochemical sensor for the determination of aflatoxin B 1 (AFB 1 ) was constructed on a glassy carbon electrode by stepwise modification of functional multiwalled carbon nanotubes (MCNTs), Au/Pt bimetallic nanoparticles (Au/PtNPs), and a thin imprinted film. The fabrication of a homogeneous porous poly o -phenylenediamine (POPD)-grafted Au/Pt bimetallic multiwalled carbon nanotubes nanocomposite film was conducted by controllable electrodepositing technology. The sensitivity of the sensor was improved greatly because of the nanocomposite functional layer; the proposed sensor exhibited excellent selectivity toward AFB 1 owing to the porous molecular imprinted polymer (MIP) film. The surface morphologies of the modified electrodes were characterized using a scanning electron microscope. The performance of the imprinted sensor was investigated by cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy in detail. A linear relationship between the sensor response signal and the logarithm of AFB 1 concentrations ranging from 1 × 10 −10 to 1 × 10 −5 mol L −1 was obtained with a detection limit of 0.03 nmol L −1 . It was applied to detect AFB 1 in hogwash oil successfully.
研究领域:
分析化学
·
食品安全检测
·
纳米材料应用
✓ 已验证
DOI
高影响因子
Advanced Sensor and Energy Materials
·
2024
·
IF 0
Yu Liu,Xu Zeng,Yulong Wu,Habib Ullah Khan,Fei Xiao,Bao Yu Xia,Yimin Sun
The development of technologically advanced fiber-based flexible microelectrodes has been of extensive research interest in healthcare systems because of their unique construction and synergistic effect on multifunctional properties. In this work, we constructed functional MXene fiber (MXF) by a simple and versatile wet spinning method, and then, a well-aligned ZIF-67 nanoarray was grown in situ on the surface. Using the chemical vapor deposition (CVD) method, carbon nanotubes (CNTs) were produced on MXF via the pyrolysis of ZIF-67 and melamine. Finally, Pt nanoparticles were electrodeposited on the CNTs forest, and a Pt@CNTs/MXF electrode was obtained. Owing to the plethora of surface active sites and the synergistic effects between MXene, CNTs, and Pt nanoparticles, the as-fabricated fiber electrode enabled the precise detection of ammonia under alkaline conditions via differential pulse voltammetry (DPV), which exhibited a linear range of 0.1 μM-10 mM and a detection limit of 73.2 nM. Due to their good performance in ammonia detection, Pt@CNTs/MXF electrodes could be adopted to determine the ammonia concentration in urine for clinical estimation, which provides a practical approach for the diagnosis of urinary ammonia-associated diseases.
研究领域:
生物医学工程
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分析化学
·
纳米材料
·
传感器技术
✓ 已验证
DOI
ANALYTICAL BIOCHEMISTRY
·
2018
·
IF 2.275
Wei Zheng,Haiyan Wu,Yan Jiang,Jicheng Xu,Xin Li,Wenchi Zhang,Fengxian Qiu
In this work, a novel molecularly imprinted electrochemical sensor (MIECS) based on a glassy carbon electrode (GCE) modified with carbon dots (CDs) and chitosan (CS) for the determination of glucose was proposed for the first time. The use of the environmental-friendly CDs and CS as electrode modifications improved the active area and electron-transport ability substantially, while 3-aminobenzeneboronic acid was used as a functional monomer and glucose as template for the fabrication of molecularly imprinted polymer (MIP) film to detect glucose via differential pulse voltammetry . Transmission electron microscope , Fourier transform infrared spectroscopy , energy dispersive x-ray spectrometry, cyclic voltammetry and electrochemical impedance spectroscopy (EIS) were applied to characterize the fabricated sensor. Experimental conditions such as molar ratio of functional monomer to template, volume ratio of CDs to CS, incubation time and elution time were optimized. By using glucose as a model analyte, the MIECS had two assay ranges of 0.5–40 μM and 50–600 μM, and fairly low limit of detection (LOD) of 0.09 μM (S/N = 3) under the optimized conditions. The MIECS also exhibited excellent selectivity, good reproducibility, and stability. The proposed sensor was successfully applied to a preliminary test for glucose analysis in real human blood serum samples.
研究领域:
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 4
·1-11
·
IF 5.7
Yang Jing,Deng Changxi,Zhong Wei,Peng Guanwei,Zou Jin,Lu Yan,Gao Yansha,Li Mingfang,Zhang Songbai,Lu Limin
Heterostructured TiO 2 @MXene rich in oxygen vacancies defects (VO-TiO 2 @MXene) has been developed to construct an electrochemical sensing platform for imidacloprid (IMI) determination. For the material design, TiO 2 nanoparticles were firstly in situ grown on MXene and used as a scaffolding to prevent the stack of MXene nanosheets. The obtained TiO 2 @MXene heterostructure displays excellent layered structure and large specific surface area. After that, electrochemical activation is utilized to treat TiO 2 @MXene, which greatly increases the concentration of surface oxygen vacancies (VOs), thereby remarkably enhancing the conductivity and adsorption capacity of the composite. Accordingly, the prepared VO-TiO 2 @MXene displays excellent electrocatalytic activity toward the reduction of IMI. Under optimum conditions, cyclic voltammetry and linear sweep voltammetry techniques were utilized to investigate the electrochemical behavior of IMI at the VO-TiO 2 @MXene/GCE. The proposed sensor based on VO-TiO 2 @MXene presents an obvious reduction peak at -1.05 V(vs. Hg|Hg 2 Cl 2 ) with two linear ranges from 0.07 - 10.0 μM and 10.0 - 70.0 μM with a detection limit of 23.3 nM (S/N= 3). Furthermore, the sensor provides a reliable result for detecting IMI in fruit and vegetable samples with a recovery of 97.9-103% and RSD≤ 4.3%. Graphical abstract
A sensitive electrochemical sensing platform was reported for imidacloprid (IMI) determination based on heterostructured TiO 2 @MXene rich in oxygen vacancy defects.
研究领域:
材料科学
·
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2024
·Vol. 110
·期 2
·280-290
·
IF 2.3
Chen Liqiang,Tian Shuangshuang,Zhang Jinghua,Zhang Hong,Sheng Liangquan,Wang Xinxin,Fan Jiajing,Huang Deqian
A novel electrochemical sensor utilizing ZrO 2 and ZnO hybrid nanocomposites was developed for the specific detection of dopamine (DA) with ultra-high sensitivity and selectivity. The structure and electrochemical properties of the composites were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), a gas adsorption apparatus (BET), and electrochemical analysis. The results indicate that in the ZrO 2 /ZnO nanocomposite, ZrO 2 exhibits a large specific surface area and abundant active sites, which can accelerate the oxidation-reduction reaction of DA. Meanwhile, ZnO nanomaterials demonstrate high electronic conductivity, enhancing the sensor’s adsorption capability for DA. The electrochemical sensor has a detection limit of 94.1 nM within the linear range of 0.5–100 μM. Assays were conducted using human serum samples at physiological pH. The recovery rate was 98.5–101.0%, and the relative standard deviations were less than 5%. This suggests that the electrochemical sensor holds promise for bioanalysis and disease monitoring. Graphical Abstract
研究领域:
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
CHINESE JOURNAL OF CHEMISTRY
·
2015
·Vol. 33
·期 2
·185-191
·
IF 1.578
Lin Tan,Guo Wang,Nali Chen,Jianqiang Zhang,Huixia Feng
Graphene/mono-(6-amino-6-deoxy)- β -cyclodextrin multilayer films composed of graphene sheet (GS) and mono-(6-amino-6-deoxy)- β -cyclodextrin (NH 2 - β -CD) were fabricated easily by two steps. First, negatively charged graphene oxide (GO) and positively charged mono-(6-amino-6-deoxy)- β -cyclodextrin (NH 2 - β -CD) were layer-by-layer (LBL) self-assembled on glassy carbon electrode (GCE) modified with a layer of poly(diallyldimethylammonium chloride) (PDDA). Then graphene/mono-(6-amino-6-deoxy)- β -cyclodextrin (GS/NH 2 - β -CD) multilayer films were built up by electrochemical reduction of graphene oxide/mono-(6-amino-6-deoxy)- β -cyclodextrin (GO/NH 2 - β -CD). Combining the high surface area of GS and the active recognition sites on β -cyclodextrin ( β -CD), the GS/NH 2 - β -CD multilayer films show excellent electrochemical sensing performance for the detection of DA with an extraordinary broad linear range from 2.53 to 980.05 µmol·L −1 . This study offers a simple route to the controllable formation of graphene-based electrochemical sensor for the detection of DA.
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）