ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
·
2015
·
IF 2.084
Ting Wang,Xiaoxian Zhang,Dayong Tian,Ya Gao,Zhifen Lin,Ying Liu,Lingyun Kong
CO 2 , as the typical greenhouse gas causing the greenhouse effect, is a major global environmental problem and has attracted increasing attention from governments. Using algae to eliminate CO 2 , which has been proposed as an effective way to reduce the greenhouse effect in the past decades, can be disturbed by a growing number of artificial chemicals. Thus, seven types of chemicals and Selenastrum capricornutum (algae) were examined in this study, and the good consistency between the toxicity of artificial chemicals to algae and the disturbance of carbon fixation by the chemicals was revealed. This consistency showed that the disturbance of an increasing number of artificial chemicals to the carbon fixation of algae might be a “malware” worsening the global greenhouse effect. Therefore, this study proposes an original, promising index to assess the risk of deepening the greenhouse effect by artificial chemicals before they are produced and marketed.
研究领域:
环境科学
·
生物学
✓ 已验证
DOI
高影响因子
MOLECULES
·
2014
·Vol. 19
·期 7
·9675-9688
·
IF 2.095
Pu Jing,Li-Hua Song,Shan-Qi Shen,Shu-Juan Zhao,Jie Pang,Bing-Jun Qian
Red radish (RaphanusL.) pickles are popular appetizers or spices in Asian-style cuisine. However, tons of radish brines are generated as wastes from industrial radish pickle production. In this study, we evaluated the dynamic changes in colour properties, phenolics, anthocyanin profiles, phenolic acid composition, flavonoids, and antioxidant properties in radish brines during lactic acid fermentation. The results showed that five flavonoids detected were four anthocyanins and one kaempferol derivative, including pelargonidin-3-digluoside-5-glucoside derivatives acylated withp-coumaric acid, ferulic acid,p-coumaric and manolic acids, or ferulic and malonic acids. Amounts ranged from 15.5–19.3 µg/mL in total monomeric anthocyanins, and kaempferol-3,7-diglycoside (15–30 µg/mL). 4-Hydroxy-benzoic, gentisic, vanillic, syringic,p-coumaric, ferulic, sinapic and salicylic acids were detected in amounts that varied from 70.2–92.2 µg/mL, whereas the total phenolic content was 206–220 µg/mL. The change in colour of the brine was associated with the accumulation of lactic acid and anthocyanins. The ORAC and Fe2+chelation capacity of radish brines generally decreased, whereas the reducing power measured as FRAP values was increased during the fermentation from day 5 to day 14. This study provided information on the phytochemicals and the antioxidative activities of red radish fermentation waste that might lead to further utilization as nutraceuticals or natural colorants.Keywords:radish;brine;fermentation;phytochemicals;antioxidant
研究领域:
食品科学
·
植物化学
✓ 已验证
DOI
PubMed
高影响因子
MOLECULES
·
2019
·Vol. 24
·期 20
·3747
·
IF 3.06
Weiyu Yang,Ling Guo,Fenfen Li,Xin Liu,Shaoping Nie,Mingyong Xie,Danfei Huang
Myricetin (Myr) is a phytochemical with many functional properties. However, its hydrophobicity, low bioavailability, and stability limit its application. In this study, octadecanoate oat β-glucan (OGE) was synthesized and gained recognition as a self-assembled micelle forming a polymer with a critical micelle concentration (CMC) of 59.4 μg/mL. The Myr-loaded OGE micelle was then prepared and characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), X-ray diffractometer (XRD), and Fourier-transform infrared spectroscopy (FT-IR) spectra. The water solubility of Myr was greatly enhanced by forming the Myr/OGE inclusion complex. Consequently, compared to free Myr, the retention of Myr in Myr-loaded OGE micelle was effectively increased during the intestinal digestion phase, and its antioxidant activity was also improved. Overall, our findings demonstrated the potential applications of OGE polymer for the development of prospective micelle in health food, cosmetics, and pharmaceutical fields because they can aid in the delivery of hydrophobic functional compounds like Myr.Keywords:phytochemicals;myricetin;amphiphilicity;micelle;self-assembly
研究领域:
食品科学
·
药学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Arthropod-Plant Interactions
·
2023
·Vol. 17
·期 5
·673-685
·
IF 1.6
Liu Bin,Chen Hui
Bark beetles mainly rely on detoxification enzymes to overcome the defensive oleoresin terpenes of their host. Insect Carboxylesterases (CarEs) play an important role in the detoxification of plant allelochemicals and insecticides. Nevertheless, the functions of specific CarE genes in metabolization of exogenous substances are still unclear in the Chinese white pine beetle, Dendroctonus armandi . In this study, we sequenced and characterized the full-length cDNAs of six CarE ( DaEST1 - DaEST6) genes from D. armandi . Spatiotemporal expression profiling showed that the expression of DaEST1, DaEST3 and DaEST4 in D. armandi was higher in the larval and adult stages, and these genes mainly expressed in fat body, Malpighian tubules and midgut. Moreover, the expression of DaEST1, DaEST3 and DaEST4 was significantly induced after treatment with four terpenoids. Importantly, disruption of DaEST3 significantly inhibited the CarE activity and reduced the tolerance of adults to host allelochemicals in D. armandi . Additionally, treatment with triphenyl phosphate to adults also reduced the tolerance after terpenoids exposure, which resulted in a significant decrease of CarE activity, leading to a significant improvement of mortality in D. armandi . These results indicate that DaEST3 plays an important role in determining the tolerance to host allelochemicals in D. armandi , which might be of great significance in developing new therapeutic methods to pest control.
研究领域:
昆虫学
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
Food Bioscience
·
2021
·
IF 4.24
Yao Pan,Hongyan Li,Xuan Chen,Yawei Fan,Bing Zhang,Rong Liu,Ze-yuan Deng
Lipophilic (lycopene, β-carotene) and hydrophilic (caffeic acid, p -coumaric acid) phytochemicals were mixed in molar mass at different concentrations/ratios to explore the antioxidant interactions on H 2 O 2 -treated H9c2 cells. Reactive oxide species (ROS), expression of antioxidant enzymes , and oxidation products were analyzed and evaluated by synergistic rate (SR) and combination index (CI). At constant concentrations, antioxidant interactions were influenced by ratios. Group contained more hydrophilic compounds (eg., p -coumaric acid:β-carotene=9:1) showed antioxidant synergism (SR=22.33±1.23, SR>0) at 3.0 μM, while groups that contained more lipophilic compounds (eg., p -coumaric acid:β-carotene=1:9) showed antioxidant antagonism (SR=-11.68±1.25, SR<0) at 3.0 μM. Antioxidant interactions were also influenced by concentrations. From results, ROS generation of group ( p -coumaric acid:β-carotene=1:9) changed from synergism (SR=12.27±2.34, SR>0) to antagonism (SR=-11.68±1.25, SR<0) as their total concentrations increased from 1.5 μM to 3.0 μM. Therefore, this study discussed the possible mechanism of ratio and concentration on the antioxidant interaction among hydrophilic and lipophilic phytochemicals. It also suggested that proper concentrations/ratios of hydrophilic and lipophilic phytochemicals should be considered in diet and formulation of functional foods.
研究领域:
药理学
·
营养学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2021
·
IF 8.071
Zaiming Chen,Jianfei Wang,Yuefeng Wang,Bing Li,Meizhen Wang
Pyrogenic char (biochar) with a high sorption capacity (B-HSC) can sequester hazardous chemicals (e.g., phenanthrene). However, when sorption inhibits bioavailability of some functional chemicals (e.g., the herbicidal efficacy of diuron in soil), biochar with a low sorption capacity (B-LSC) is required to prevent sorption effects. The pyrolytic B-HSC generation has been reported, but information on B-LSC formation is scarce. How fast B-HSC and B-LSC could be generated is unknown until now. Here, biochars were rapidly prepared (the shortest heating time reached 5 min and the cooling time reached < 30 min) by a direct-pyrolysis method by directly exposing packaged rice straw and pine wood to 350 °C, 500 °C and 700 °C and out-of-furnace cooling at room temperature. The sorption of diuron, phenanthrene , and twelve other chemicals was investigated. B–HSCs were obtained within 30 min of rice straw pyrolysis , and the biochar K d values quickly increased to 7-730-fold that of the raw biomass as –OH and C–O–C in (hemi)cellulose of rice straw rapidly degraded, increasing hydrophobic interactions between the char and chemicals (solubility ≤ 82.8 g/L). In contrast, B-LSCs were generated within 30 min of PW pyrolysis, and the K d values of the biochars were 0.2–3.0-fold that of the raw biomass, as the surface area development and hydrophobicity-driven sorption were probably delayed by the late degradation of lignin aromatic C–O and phenolic –OH. Biochar amendment revealed an enhancement effect of B-HSC but not of B-LSC on soil sorption. The fast formation of B-LSC and B-HSC provides a guide to develop time- and cost-effective technique in pyrolytically producing weakly or strongly sorbing biochars for organic chemical management.
研究领域:
环境科学
·
土壤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zi-Hui Cai,Xin-Yue Dong,Li-Tao Wang,Wan-Mei Zhou,Ya-Ning Wang,Jie Yang,Yu-Jie Fu
The current large-scale use of organic and some toxic reagents hinders the development of plant secondary metabolite extraction and processing industry. Here, a biphasic temperature-responsive solvent system consisting of hydrophilic deep eutectic solvent (choline chloride: levulinic acid) and fatty acid-based hydrophobic deep eutectic solvent is developed. Some characteristics of this intelligent solvent system, including hundreds of synthesis ratios and corresponding switching temperatures, phase ratios, etc., have been comprehensively determined. Subsequently, it is applied to different plant matrices. The extraction efficiencies ranged from 1.006 to 6.807 times higher than those of conventional organic reagents, with separation efficiencies ranging from 60.7 % to 100 %, besides the fact that the hydrophilic components are almost entirely distributed in the lower phase. The recovery of targeted phytochemicals achieves satisfactory results during the simultaneous extraction and enrichment process. Mechanisms of switching, extraction, and enrichment have been elucidated to a certain extent from the point of view of chemical computational simulations. Overall, this new green solvent system is universal and can be applied to a wide range of phytochemicals extraction and separation from plants in a one-pot operating unit. Also, it is almost the greenest of the temperature-responsive solvents studied so far and has superior application prospects.
研究领域:
植物学
·
绿色化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Jun Young Kim,Kang Hoon Lee,Jae Won Lee,Imtiaz Afzal Khan,Jong-Oh Kim
In this study, the removal efficiency of chemicals of emerging concerns (CECs) was evaluated under exposure to various doses of UV/H 2 O 2 -based oxidation processes in combination with membrane filtration for three cleaning cycles. Polyethersulphone (PES) and polyvinylidene fluoride (PVDF) materials based membranes were used for this study. The chemical cleaning of the membranes was performed by immersion of the membranes into 1 N HCl followed by adding 3000 mg.L −1 NaOCl for 1hr. Degradation and filtration performance was evaluated using Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) and total organic carbon (TOC) analysis. Membrane fouling analysis for assessing the comparative performance of PES and PVDF membranes was determined by specific fouling and fouling indices evaluation. Membrane characterization results show that the alkynes and carbonyl group formation are due to dehydrofluorination and oxidation of PVDF and PES membranes under the attack of foulants and cleaning chemicals, which resulted in a reduction of fluoride percentage and an increase in sulfur percentage in the PVDF and PES membranes. A decrease in the hydrophilicity of the membranes in underexposed conditions was observed and is consistent with an increase in dose. Degradation results of CECs follow with the highest removal efficiency of chlortetracycline (CTC) followed by atenolol (ATL), acetaminophen (ACT), and caffeine (CAF) degradation due to attack on the aromatic ring and the carbonyl group of CECs by OH exposure. Membrane exposed at 3 mg.L-1 dose of UV/H 2 O 2 -based CECs shows minimum alteration with higher filtration efficiency and lower fouling, particularly in PES membranes.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2020
·Vol. 22
·期 19
·6579-6587
·
IF 9.48
Xiaohao Liu,Xiaodong Liu,Haiyong Wang,Tianci Xiao,Ying Zhang,Longlong Ma
Efficient conversion of renewable cellulose to high value-added C3 chemicals is a great challenge in the field of biomass valorization. In this work, we found that the combination of Co and Sn could significantly improve the efficiency of cellulose conversion to acetol. 54.4% yield of acetol and 66.6% total yield of C3 products were obtained when using 2%Sn–10%Co/SiO2 (2 wt% Sn content) as a catalyst. However, using the same Sn content of 2%Sn–10%Ni/SiO2, no acetol and only 7.1% yield of C3 products were produced. By studying the effects of different Sn and Co concentrations on cellulose conversion, it was found that the Sn species play an important role in catalyzing glucose conversion to C3 intermediates, while Co mainly played a role in hydrogenation, the same as Ni. The study demonstrated that Sn–Co/SiO2 with low Sn content can convert glucose to C3 intermediates more efficiently than the Sn–Ni/SiO2 catalyst. Moreover, Sn–Co/SiO2 could effectively convert C3 intermediates to acetol at a high temperature which is essential for acetol production from cellulose; but under the same conditions, the Sn–Ni/SiO2 catalyst tended to catalyze the polymerization of C3 intermediates. A series of characterization methods including AAS, TEM, HRTEM, EDS, XRD, ex situ XPS, in situ XPS, and CO2-TPD found that the combination of Sn and Co could significantly increase the noninteger valent SnOx species in the catalyst. These species increased the basicity of the catalyst and were beneficial in catalyzing the isomerization of glucose and the retro-aldol condensation of fructose.
研究领域:
生物质能
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
·
2022
·Vol. 53
·期 6
·1084-1100
·
IF 3.402
Wei-Wei Mao,Zi-Chen Zhao,Gui-Hua Li,Wei-Liang Guo,Ze-Hao Ding,Shi-Feng Wang,Yun Sun,Zhen-Jie Cao,Jian-Long Li,Yong-Can Zhou
Cryptocaryon irritans , one of the most devastating holotrichous ciliated protozoans, causes massive economic losses in the pompano, Trachinotus ovatus , mariculture industries. Considering the many advantages of phytochemicals, such as low cost, low residuals, and low pollution, they can be a good alternative for the prevention and control of C. irritans infestations. In this study, 14 phytochemicals were evaluated for their antiparasitic activity against the theront of C. irritans , and nine showed significant antiparasitic activity. Nerolidol was the most promising compound, causing 100% mortality of theronts with 30-min exposure at a concentration of 10.0 μl/L. The half-maximal inhibitory concentrations ( IC 50 s) of nerolidol on C. irritans theronts, protomonts, and tomonts were 2.1, 13.3, and 7.1 μl/L, respectively. Abnormal morphologies of the theronts, trophonts, and tomonts were observed after exposure to 10.0, 30.0, and 10.0 μl/L nerolidol solution for 15 min, 30 min, and 480 min, respectively. A diet supplemented with 2.3 ml/kg of nerolidol reduced the number of trophonts on the gills of pompano by 95.7% decrease compared with the control groups and the theront chemotaxis to pompano mucus and sera, while increased the survival rate of infected pompanos by 24.44%, and had no significant effect on pompano hindgut and serum myeloperoxidase. These results suggest that nerolidol is a new potential drug for controlling fish cryptocaryonosis.
研究领域:
水产养殖学
·
寄生虫学
·
药理学
✓ 已验证
DOI
高影响因子
Life-Basel
·
2024
·Vol. 14
·期 6
·713
·
IF 3.2
Leyuan Liu,Lang Yang,Jinxi Yuan,Jie Zhang,Chenhao Liu,Hongxu Zhou,Wei Liu,Guirong Wang
The oriental fruit fly,Bactrocera dorsalis(Hendel), poses a significant threat to the global fruit industry, causing damage to diverse fruits like citrus, mango, and guava. Chemical pesticides have limited effectiveness, and pesticide residues and pesticide resistance are pressing issues. Therefore, it is essential to develop environmentally friendly pest control methods to address this problem. Behavior-modifying chemicals, including male attractants and intersex protein baits, play a critical role in the control ofB. dorsalis. The mature host fruit serves as both an oviposition site and food source under natural conditions, making it a potential attraction source for oriental fruit flies. Orange,Citrus sinensis, is a main host ofB. dorsalis, and commercial orange juice is a common attractant for the egg laying ofB. dorsalis. Although it can both attract and elicit oviposition behaviors inB. dorsalisadults, its active components are still unclear. This study utilized analytical chemistry, behavioral tests, and electrophysiology to identify the active components of commercial orange juice that attractB. dorsalis, with the aim of providing a reference for the development of behavior-modifying chemical-based techniques to controlB. dorsalis.Five compounds with a high abundance were identified via a GC-MS, including D-Limonene, butanoic acid ethyl ester, β-myrcene, linalool, and α-terpineol. Behavioral and electrophysiological experiments uncovered that D-Limonene was the active substance that was the main attractant in the mixture of these five substances, evoking a strong electrophysiological response in adultB. dorsalis. D-Limonene strongly attracts adultB. dorsalisonly when they are sexually mature, and the attraction is not rhythmic. Olfaction plays a leading role in the attraction of D-Limonene to adultB. dorsalis, andOrco−/−mediates the perception of D-Limonene byB. dorsalis. Overall, D-Limonene is one of the key attractant compounds forB. dorsalisin the volatile compounds of commercial orange juice, offering possible support for the development of behavior-modifying chemical-based technology to controlB. dorsalisin the future.
研究领域:
昆虫学
·
化学生态学
·
害虫防治
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
·
2016
·
IF 3.584
Lijiao Kan,Shaoping Nie,Jielun Hu,Sunan Wang,Steve W. Cui,Yawen Li,Sifan Xu,Yue Wu,Junqiao Wang,Zhouya Bai,Mingyong Xie
Detailed characterization in nutrients and phytochemicals with antioxidant activities of 26 kidney beans was performed. The kidney beans contained high levels of dietary fiber (29.32–46.77%), resistant starch (9.16–18.09%) and protein (22.06–32.63%) but low levels of lipid (1.05–2.83%) and sugars (1.55–9.07%). The monosaccharide composition of soluble fiber was dominated by arabinose , galactose , mannose and galacturonic acid . The ratio of essential amino acid to the total amino acid was ranged from 0.29 to 0.36. The predominant fatty acid was polyunsaturated fatty acids , accounting for 47.54–67.26% of total fatty acids. The total tocopherol content was in the range of 12.83–68.35 μg/g, predominantly γ-tocopherol, followed by δ-tocopherol. In addition, certain levels of total phenolics and flavonoids with respective values of 0.25–3.79 mg gallic acid equivalent/g dry weight and 0.19–7.05 mg rutin equivalent/g dry weight resulted in significant antioxidant activities. And a good correlation was observed between TPC and FRAP values (R2 = 0.8030). The results indicated that kidney beans are excellent sources of health-promoting compounds.
研究领域:
食品科学
·
植物学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）