Journal of Materials Chemistry A
·
2016
·Vol. 4
·期 46
·18067-18074
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IF 8.262
Jing Yang,Xiaofeng Li,Shuang Han,Yiting Zhang,Peng Min,Nikhil Koratkar,Zhong-Zhen Yu
High density graphene hybrid aerogels with enhanced thermal conductivity and compressive properties are fabricated by self-assembly of aqueous mixtures of graphene oxide and high-quality graphene nanoplatelets (GNPs) followed by a convenient and cost-effective air drying process. The reduced graphene oxide sheets form an integrated three-dimensional network to accommodate GNPs, while the GNPs act as reinforcements to avoid excessive volume shrinkage of the network during the air drying process. Octadecanol is thus easily impregnated into the porous graphene network to obtain octadecanol/graphene phase change composites (PCCs) with exceptional thermal conductivities. The PCC with 12 wt% graphene exhibits a thermal conductivity of ∼5.92 W m−1 K−1 that is 26-fold higher than that of neat 1-octadecanol while maintaining a high latent heat of fusion (∼202.8 J g−1). Even when compressed by a high weight at ∼70 °C, the PCC still retains shape stability without any leakage. Such abilities to endow PCCs with exceptional shape stability and to boost their thermal conductivity by an order-of-magnitude without incurring a significant loss in the heat of fusion are important attributes in enabling their practical application as latent heat storage/release units for thermal management and thermal protection.
研究领域:
材料科学
·
热管理技术
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产品关联
DOI
高影响因子
SOLAR ENERGY
·
2018
·
IF 4.374
Xiuli Wang,Xiaomin Cheng,Yuanyuan Li,Ge Li,Jun Xu
A self-assembly method is introduced to prepare composite phase change materials (PCMs) consisting of 1-octadecanol (OD) and graphene. The shape stability and thermal properties of 1-octadecanol/graphene composite PCMs with three-dimensional network structure are investigated. Graphene is dispersed evenly in OD matrix and the three-dimensional network structure is getting tighter with increasing ratio of graphene. OD is completely encapsulated at relatively low amount of graphene about 1.5 wt%. XRD and Raman results show that the combination between OD and graphene is physical adsorption. The 1-octadecanol/graphene (OG) composite phase change materials possess excellent shape stability, which can prevent the leakage of molten OD during phase transition. In addition, around 99.3% phase change enthalpy of pure OD is maintained by connected network structure of graphene while the melting and solidifying temperature merely have small fluctuations. The thermal conductivity of composite phase change material with 1.5 wt% graphene increases to 0.358 W/(m K), which is 1.5 times higher than that of pure OD. Furthermore, the porous network of graphene can delay the evaporation and thermal decomposition point of the composite phase change materials, thus extending the operating temperature of OD efficiently. This work provides a promising way to encapsulate low-temperature organic phase change materials with little carbon additives, and enhance the thermophysical properties of base materials simultaneously.
研究领域:
材料科学
·
能源工程
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DOI
高影响因子
AQUACULTURE INTERNATIONAL
·
2024
·Vol. 32
·期 5
·5461-5494
·
IF 2.2
Alhoshy Mayada,Shehata Akram Ismael,Habib Yusuf Jibril,Wang Xuexi,Wang Yilei,Zhang Ziping
Crayfish species like Cherax quadricarinatus are crucial nutrients that contribute to the world economy but face challenges in production due to dietary supplements. Octacosanol offers diverse health benefits, from immunity boosts to anti-inflammatory and anti-tumor effects. The current investigation assessed the ovarian changes, immune reaction, availability of antioxidants, gene response pattern, and entire organ performance of the red claw crayfish after supplementation with different levels of octacosanol. Two hundred twenty-five C. quadricarinatus with an initial weight of 53 ± 1.11 (g/crayfish) were randomly stocked into fiberglass tanks (15 crayfish/tank) and fed each day with three diverse dietary octacosanols. Different levels of octacosanol (4, 8, 12, and 16 mg/kg) were tested in triplicates over 60 days, denoted as D1, D2, D3, and D4, respectively, excluding the control group. The study revealed that 8 mg/kg octacosanol effectively enhances growth and feed utilization in C. quadricarinatus , while also improving ovarian performance by increasing hepatosomatic index (HSI), gonadosomatic index (GSI), and condition factor (CF). Additionally, it decreased levels of MDA and NO in crayfish. Supplementation with 16 mg/kg octacosanol boosted antioxidant capacity by enhancing activities of T-AOC and SOD, as well as influencing nonspecific immune enzymes in the hepatopancreas at doses of D3 (12 mg/kg) and D4 (16 mg/kg). Furthermore, it positively impacted GLU and protein profiles while reducing levels of T-BIL, T-CHOL, TG, LDL-c, and VLDL-c in crayfish. These dietary interventions also regulated gene expression associated with reproduction, lipid metabolism, antioxidants, and immune response in various organs of C. quadricarinatus . Octacosanol demonstrated potential as a safe and effective feed additive. According to quadratic regression analysis, nutritional supplementation of octacosanol at 9 mg/kg diet is considered the recommended dosage in the red claw crayfish diet.
研究领域:
水产养殖学
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营养学
·
分子生物学
✓ 已验证
DOI
高影响因子
ENERGY & FUELS
·
2021
·
IF 3.605
Shuang Yao,Tong Zhang,Xiaoyu Tang,Delong Li,Weihao Zhang,Dong Lin,Ruiying Li,Hao Yan,Yibin Liu,Xiang Feng,Xiaobo Chen,Xin Zhou,Chaohe Yang
As a potential alternative for fossil feedstocks, renewable natural oils are highly desirable for producing fuels or high added-value chemicals. Herein, catalytic transfer hydrogenation of methyl stearate to octadecanol using methanol and water as hydrogen donors was investigated over Co/hydroxyapatite (HAP) catalysts synthesized by distinct methods. Multicharacterizations revealed that the strong interaction between Co and the HAP support of the Co/HAP catalysts could enhance the electron transferability, resulting in the excellent methyl stearate conversion (94.8%) and octadecanol selectivity (67.7%) at 290 °C in 5 h. The characterizations and density functional theory (DFT) calculations confirmed that the combined Co0/Coδ+ active sites could synergistically boost the generation of H2 and the hydrogenation of methyl stearate in the methanol/water system. In addition, the effects of various reaction conditions (e.g., the amount of methanol, reaction temperature, reaction time, and catalyst loading) were investigated in detail to understand the plausible reaction pathways. The results may have guiding significance on designing catalysts for efficient conversion of fatty acid methyl esters.
研究领域:
化学工程
·
催化科学
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DOI
高影响因子
Foods
·
2022
·Vol. 12
·期 1
·112
·
IF 5.561
Yin-Yi Ding,Yuxiang Pan,Wanyue Zhang,Yijing Sheng,Yanyun Cao,Zhenyu Gu,Qing Shen,Qingcheng Wang,Xi Chen
1-Octacosanol (Octa) is a natural compound with several beneficial properties. However, its poor water solubility and metabolism in the digestive tract reduce its efficacy. The Octa-GA-Malt-PPI microcapsule was prepared as follows: gum Arabic (GA):maltose (Malt):pea protein isolate (PPI) = 2:1:2; core:shell = 1:7.5; emulsification temperature 70 °C; pH 9.0. An in vitro simulated gastrointestinal tract was used to analyze the digestion behavior. C57BL/6 mice were selected to establish an obesity model induced by a high-fat diet (HFD) to evaluate the effect of Octa monomer and the microcapsule. The diffusivity in water and storage stability of Octa improved after encapsulation. The microcapsule was ascribed to electrostatic interactions, hydrogen bonding, and hydrophobic interactions. The sustained release of Octa from the microcapsule was observed in a simulated gastrointestinal tract. Compared with Octa monomer, the microcapsule was more effective in alleviating the symptoms of weight gain, hypertension, and hyperlipidemia induced by HFD in mice. In conclusion, the construction of microcapsule structure can improve the dispersibility and stability of Octa in water, achieve sustained release of Octa in the gastrointestinal tract, and improve its efficiency in alleviating the effects of HFD on the body.Keywords:1-Octacosanol;microcapsule;storage stability;sustained release;HFD-induced obesity mice
研究领域:
药学
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营养学
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生物技术
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产品关联
DOI
PubMed
高影响因子
ENERGY AND BUILDINGS
·
2022
·
IF 7.201
Z.H. Kuai,Ting Yan,Y.J. Huo,Kai Wang,W.G. Pan
At present, low heat storage capacity of organic phase change materials (PCMs) becomes a common problem, and the addition of matrix can contribute to its application in practical engineering. Mixing the porous expanded graphite (EG) with Co 3 O 4 via carbonation of ZIF-67 uniformly, the composite materials PVP@Co 3 O 4 /EG were prepared by crosslinking the agent PVP (polyvinyl pyrrolidone), simultaneously the multilayer structure porous OC-PVP@Co 3 O 4 /EG composites were prepared by melt-blending method with octadecanol (OC). The thermophysical properties of the composite PCMs appeared the difference by adjusting the ratio of OC to Co 3 O 4 . The micromorphology, phase transition enthalpy and phase transition temperature of composite PCMs were determined by scanning electron microscope (SEM) and differential scanning calorimeter (DSC). The multilayer structure prepared by Co 3 O 4 and EG is conducive to the effective transmission of phonons around the axial point, and achieves the goal of efficient heat transfer between PCMs and the external environment. The obtained OC-PVP@Co 3 O 4 /EG (Co 3 O 4 :EG = 1:8) PCMs exhibited excellent thermal conductivity (11.4 W∙m −1 ∙K −1 ), large phase change enthalpy (187.04 kJ∙kg −1 ). The infrared imaging verified that the infrared light intensity of two thermally conductive substrates (Co 3 O 4 :EG = 1:4, 1:8) in the exothermic stage was less than the ratio of Co 3 O 4 :EG is 1:4 and 1:8, which was in accordance with the results of the charging/discharging experiments.
研究领域:
材料科学
·
热能工程
·
能量存储
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2018
·Vol. 53
·期 20
·14456-14468
·
IF 2.993
Dou Qianqian,Wong Ka Wai,Li Yang,Ng Ka Ming
The localized surface plasmon resonance (LSPR) behavior of indium-doped ZnO (IZO) nanocrystals synthesized in different solvents was studied. 1-octadecanol, oleic acid, oleyl alcohol, oleyl amine and 1-octadecene were used as solvent(s) and co-solvent(s) in the pyrolysis synthesis of indium-doped ZnO (IZO) nanoparticles. The results showed that the nanocrystals from a solvent system consisting of 1-octadecene, 1-octadecanol, and oleic acid exhibited enhanced LSPR near-infrared radiation absorption without sacrificing transparency in the visible region. The indium-rich core verified using ICP and XPS analysis was shown to be critical for the enhancement. The reaction mechanism of solvents on the generation of indium-rich core was elucidated through a systematic study of the reaction parameters. The interaction between the activating agent, inhibiting agent and solvent, and their effect on tuning the reactivity of dopant and host precursors were important for the formation of a nanostructure with a dopant-rich core. The solvent effect was also found in the synthesis of gallium-doped ZnO and confirmed to be a general phenomenon in the preparation of doped ZnO nanoparticles.
研究领域:
材料科学
·
纳米技术
·
光学
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DOI
高影响因子
ChemMedChem
·
2025
·
IF 3.4
Lin Li,Yanyan Wu,Weiwei Wang,Kejing Wang,Lin Chen
Prodrug-based self-assembled nanoassemblies, with carrier-free structures and high drug loading, are garnering attention for chemotherapy. Additionally, the synergistic effects of prodrug nanoassemblies combined with multiple cell death pathways deserve further exploration. Ferroptosis has emerged as a powerful nonapoptotic cell death modality, showing significant potential for tumor inhibition. Therefore, prodrug nanoassemblies combined with ferroptosis inducers may achieve amplified antitumor efficacy. Herein, a GPX4 inhibitor (ML210)-loaded SN38 prodrug nanoparticle system is developed to enhance antitumor efficacy via ferroptotic-chemotherapy synergy. In this system, SN38 is conjugated to 1-octadecanol by a disulfide linkage to construct the self-assembly prodrug. DSPE-PEG 2k is applied to stabilize nanoassemblies. It is proven that ML210 is successfully encapsulated into the SN38 prodrug nanoassemblies by the one-step precipitation method. Both prodrug nanoassemblies exhibit good stability and a GSH-responsive release profile. Furthermore, ML210-loaded nanoassemblies show stronger cytotoxicity, greater proliferation inhibition, and obvious ferroptosis activation. In the CT26 mouse model, ML210-loaded prodrug nanoassemblies demonstrated superior antitumor effects. The strategy—using prodrug as “carriers” for ferroptosis inducers—offers a promising approach for synergistic antitumor therapy. Graphical Redox-responsive SN38-SS-1-octadecanol prodrug was synthesized and used as a “carrier” for ferroptosis activator (ML210). It is proven that ML210 can be successfully encapsulated loaded into the SN38 prodrug nanoassemblies by the one-step precipitation method. Both prodrug nanoassemblies exhibited good stability and a GSH-responsive release profile. The co-assembled system of SN38 prodrug and ML210 can enhance antitumor efficiency by inducing multiple cell death pathway.
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产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Lin Li,Tiantian Lei,Kejing Wang,Yong Liu,Bingjun Sun,Lin Chen
Chemotherapy has been established as a standard therapeutic regimen for triple-negative breast cancer (TNBC). However, the efficacy of current therapeutic approaches remains suboptimal, primarily attributed to insufficient drug accumulation and the rapid development of chemoresistance. Thus, the rational design of drug delivery systems capable of triggering multimodal cell death pathways represents a promising strategy to combat TNBC. Ferroptosis emerges as a potent form of nonapoptotic cell death, showing great potential for tumor inhibition. The effective codelivery of chemotherapeutic drugs and ferroptosis activators provides potential ideas for the treatment of TNBC. Prodrug-based nanoassemblies have attracted tremendous attention in drug delivery, especially homodimeric prodrugs with ultrahigh drug loading. However, due to their symmetric structures, most homodimeric prodrugs exhibit poor self-assembly ability. Herein, two doxorubicin (DOX) homodimeric prodrugs were designed and coassembled with a GPX4 inhibitor (ML210). The incorporation of ML210 significantly promotes the stability of DOX nanoassemblies and improves the intracellular breakage of the DOX prodrug by regulating the GSH level. As a result, the ML210-driven doxorubicin homodimeric prodrug nanoassemblies exhibit high drug loading capacity, high self-assembly stability, and synergistic chemotherapy-ferroptosis effects. Our results present a viable approach to promote the self-assembly of homodimeric prodrugs while offering an efficient nanoplatform for TNBC treatment.
研究领域:
纳米医学
·
癌症治疗
·
制药纳米技术
·
分子生物学
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肿瘤学
✓ 已验证
产品关联
DOI
高影响因子
TRIBOLOGY INTERNATIONAL
·
2026
·
IF 7.6
Lin Fan,Yongqiang Wang,Jian Qin,Changqing Liu,Xuemin Sun,Ming Zhang,Yijing Liang,Qiang Chen,Shuyan Yang,Yanyan Bai,Meirong Cai
The growing demand for reliable, long-lasting equipment performance has heightened the requirements for advanced lubrication solutions. Supramolecular gel lubricants not only mitigate lubricant creep but also enhance lubrication performance through precise molecular design. A novel phosphate ester-type gelator was designed through a simple synthesis route with low-cost raw material. The supramolecular gel lubricants exhibited dual responsiveness to temperature. Reversible sol-gel transitions were achieved by controlling the system within its specific transition temperature range. The gel state restricts the mobility of the lubricant, thereby facilitating its retention and practical development. In contrast, the sol state enhances the interface adsorption of the lubricant molecules, which in turn improves their lubrication performance. In addition, the supramolecular gels exhibited favorable viscoelastic properties, along with prominent shear-thinning behavior and efficient creep recovery performance. Importantly, phosphate-based supramolecular gels exhibit exceptional lubricating properties, including excellent anti-wear behavior, low friction coefficients, and high load-bearing capacities. The lubrication mechanism indicates that under boundary lubrication, the gel rapidly adsorbs onto surfaces. Under stress and thermal influence, it reacts with the substrate to continuously form a high-load-bearing reactive film that protects friction surfaces. In mixed lubrication or elastohydrodynamic lubrication, its unique rheological properties enable the formation of a thick fluid film that reduces wear and friction. These superior properties suggest that supramolecular gel lubricants could replace conventional oils and greases under certain working conditions.
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DOI
高影响因子
JOM
·
2026
·
IF 2.3
Xiang Zhe,Xu Chengjin,Yu Haiyin,Wang Zhimei,Sun Guoxin,Cui Yu,Peng Xiujing
Titanium white waste acid contains economically recoverable concentrations of scandium (25 mg/L); however, the high acid content and presence of multiple impurity ions present significant challenges for scandium separation. In this study, a novel monoalkyl phosphate extractant, PC68, consisting of 1-hexadecyl phosphate and 1-octadecyl phosphate, was synthesized. The effects of extraction time, sulfuric acid concentration, and temperature on scandium extraction were systematically investigated using a simulated titanium white waste acid solution. The results demonstrated that equilibrium was reached within 50 min at 298 K, and that the extraction efficiency of scandium with 0.1 mol/L PC68 was 99%. Analytical techniques, including the Equimolar Series Method, FT-IR, and XPS, confirmed that PC68 extracts scandium through coordination with P-O − and P=O groups. The separation performance of scandium from titanium white waste acid was evaluated, yielding high separation factors of 1093 for Sc/Fe and 733 for Sc/Mn, which demonstrates excellent separation efficiency. The addition of 1% H 2 O 2 followed by three-stage countercurrent extraction enabled effective separation of scandium and titanium. These results provide new insights and practical approaches for scandium separation from titanium white waste acid.
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产品关联
DOI
高影响因子
Materials Today Communications
·
2025
·
IF 4.5
Zitong Chen,Tao Hu,Li Li,Wenhui Yuan
Traditional thermal insulation materials can slow down the transfer of heat while having the drawback of being vulnerable to the environmental factors and low energy utilization efficiency. In this work, the 1-octadecanol (OD) phase change aerogels based on polyvinyl alcohol (PVA) were fabricated through simple freezing-thawing cycles and lyophilization. The prepared PVA/GX/OD-4 aerogel exhibits a high phase change enthalpy up to 149.5 J/g and a thermal conductivity as low as 0.0795 W·m −1 ·K −1 , showing superior hot-water heat-preservation performance compared with ceramic fiber papers. Meanwhile, the aerogel demonstrates exceptional mechanical properties, achieving a compressive strength of 9.72 MPa at 80 % strain with a low density of only 0.2108 g/cm 3 and displays thermal reliability during continuous heating-cooling repetition processes, with only a 1.8 % decrease in heat value after 100 thermal cycles. This work offers a simple and efficient strategy for the design of thermal insulation materials with energy storage capabilities which have significant potential for practical applications within the realm of thermal insulation.
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）