International Journal of Coal Preparation and Utilization
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2025
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IF 2.1
Shengchao Yang,Sheng Dong,Jinpeng Qiao,Chao Kang,Yuqian Zhao,Yanze Wang,Jianrong Liu,Chenlong Duan,Sabereh Nazari,Miao Pan
Aiming at the problems of high quartz content, high ash content and difficult leaching of aluminum and gallium in some coal gangue, NaF-strengthened coal gangue calcination-hydrochloric acid leaching process was adopted, and the occurrence state of gallium in coal gangue was explored. The residue was analyzed by XRD and SEM, and the mechanism of NaF-strengthened coal gangue acid leaching was explored. The results show that the addition of m (NaF): m (coal gangue) = 0.06 can increase the leaching rate of aluminum in coal gangue from 33.72% to 62.03%, and the leaching rate of gallium from 43.17% to 70.15%. NaF as an additive can react with hydrochloric acid to form HF to destroy the coal gangue structure, so that hydrochloric acid can react with metakaolinite inside the quartz accumulation layer, which improves the leaching rate of aluminum and gallium. Finally, the process factors were studied separately to reveal the pattern in response to them, and it was found that the acid leaching reaction was greatly affected by internal diffusion, which provided a reference for the subsequent complexation adsorption of gallium.
研究领域:
冶金工程
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材料科学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2015
·
IF 3.091
Dandan Jiang,Naizhong Song,Sufen Liao,Yu Lian,Jiutong Ma,Qiong Jia
In the present study, the solvent extraction of vanadium from chloride medium with acidic organophosphorus extractants, primary amine N1923, and their mixtures were investigated. The organophosphorus acids included di(2-ethylhexyl) phosphoric acid (D2EHPA), 2-ethylhexylphosphonic acid mono-(2-ethylhexyl) ester (HEHEHP), and bis(2,4,4-trimethylpentyl) phosphinic acid (Cyanex272). The extraction effects from chloride medium were studied in detail, illustrating that all the three mixtures of organophosphorus acids and N1923 have synergistic effects on vanadium. As a representative, extraction stoichiometries of vanadium with D2EHPA + N1923 were studied with the methods of slope and constant mole. The extraction capacity of temperature dependency was also investigated. Moreover, the separation of vanadium, nickel, and chromium with mixtures of D2EHPA + N1923 was studied.
研究领域:
化学工程
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冶金学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Hui Yang,Baozhong Ma,Shuyang Shi,Jiancheng Yu,Yubo Liu,Zhihe Cao,Chengyan Wang
The alkali method has been proven to be an effective approach for lithium (Li) and rubidium (Rb) extraction; however, the significant dissolution of silicon (Si) remains a challenging issue. A high Si concentration in the leachate can cause filtration difficulties and pipeline blockages, while also negatively affecting phase separation during the subsequent extraction of Rb. Additionally, since the leachate needs to be recycled, the removal of Si from the leach liquor is essential. This study introduces an innovative approach of adding Al(OH) 3 for Si removal during the alkali leaching of lithium concentrate. Preliminary single-factor experiments demonstrate that Al(OH) 3 effectively reduces the Si concentration in leach liquor but also consumes NaOH, leading to a decline in Li and Rb leaching efficiency. Given the interaction between Al(OH) 3 addition and NaOH concentration on element leaching, Response Surface Methodology was employed to predict and optimize the parameters of the leaching process. Under the optimal parameters of 290 g/L NaOH concentration, 39 % Al(OH) 3 addition, and 120 °C leaching temperature, the experimental leaching efficiencies of Li, Rb, and Si were 99.8 %, 87.9 %, and 4.1 %, respectively. Subsequently, Rb was separated with Li via solvent extraction under high alkaline conditions. The single-stage extraction efficiency of Rb was 82.8 % at optimized conditions, and after four-stage countercurrent extraction, the overall Rb recovery could reach 99.2 %. The innovative alkali method proposed not only enables the synergistic extraction and separation of Li and Rb but also achieves effective Si removal and its utilization.
研究领域:
化学工程
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材料科学
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DOI
高影响因子
Journal of Food Measurement and Characterization
·
2024
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IF 2.9
Zhou Zhen,Liu Shengkai,Cui Liying,Liu Zhongkai,Li Xiaoyu,Liu Zhiguo,Fu Yujie
This study explored the ultrasonic-microwave synergistic extraction technique for obtaining cinnamaldehyde and cinnamic acid from cinnamon twigs, and determined the most favorable extraction conditions. The optimization of extraction parameters, including extraction time, ethanol concentration, liquid-to-solid ratio, and microwave power, was achieved through single-factor experiments and the response surface method. The results of the significance analysis indicated that ethanol concentration and extraction power were the two primary factors affecting the extraction rates of cinnamaldehyde and cinnamic acid. Under the optimal conditions—600 W microwave power, 75% ethanol concentration, a liquid-to-solid ratio of 1:15, and a 20-min extraction time——the extraction efficiency of cinnamaldehyde and cinnamic acid was significantly improved compared to traditional methods. Moreover, the use of the ultrasonic-microwave synergistic extraction technique demonstrated higher efficiency and lower environmental impact due to reduced waste production. The study also revealed that cinnamaldehyde and cinnamic acid in cinnamon twigs exhibited strong polarity characteristics and microwave absorption capacity, contributing to enhanced cell disruption and increased natural product release. These findings provide a robust basis for the development of an efficient and environmentally friendly extraction process for these valuable bioactive compounds.
研究领域:
化学工程
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药学
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环境科学
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DOI
高影响因子
STARCH-STARKE
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2024
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IF 2.6
Lian Li,Jia Zheng,Li Yao,Hong Wang,Yiyi Lv,Guichun Huang,Shuyi Qiu,Xiangyong Zeng,Chaoyang Wei
Baijiu distillers' grain is a solid waste after the fermentation of grains, and their high added value and deep processing and utilization require further study. This study uses the enzyme and microwave coassisted method to extract Baijiu distillers' grain polysaccharides (DGPs). Through optimization of the single-factor test and response surface methodology (RSM), the optimal conditions are solid–liquid ratio 1:30, enzyme time 50 min, enzyme temperature 50 °C, enzyme pH 5.0, microwave time 6 min, and microwave power 480 W, with a maximum DGP yield of 3.98% ± 0.03. DGP is purified by DEAE-Sepharose cellulose ion exchange chromatography to obtain four fractions, namely DGP-1, DGP-2, DGP-3, and DGP-4; the molecular weights are 2224.05, 90.99, 1478.16, and 346.19 kDa, respectively, and the main monosaccharide components are Man and Glc. The antioxidant assay shows that the four kinds of DGPs have different free radical scavenging capacities, among which DGP-2, DGP-3, and DGP-4 have good antioxidant activities. Therefore, DGP can be used as a potential natural antioxidant.
研究领域:
食品科学
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生物化学
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高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2015
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IF 4.169
Zaizhi Liu,Huiyan Gu,Lei Yang
Ionic liquids/lithium salts solvent system was successfully introduced into the separation technique for the preparation of two coumarins (aesculin and aesculetin) from Cortex fraxini. Ionic liquids/lithium salts based microwave irradiation pretreatment followed by ultrasound-microwave synergy extraction (ILSMP-UMSE) procedure was developed and optimized for the sufficient extraction of these two analytes. Several variables which can potentially influence the extraction yields, including pretreatment time and temperature, [C 4 mim]Br concentration, LiAc content, ultrasound-microwave synergy extraction (UMSE) time, liquid–solid ratio, and UMSE power were optimized by Plackett–Burman design. Among seven variables, UMSE time, liquid–solid ratio, and UMSE power were the statistically significant variables and these three factors were further optimized by Box–Behnken design to predict optimal extraction conditions and find out operability ranges with maximum extraction yields. Under optimum operating conditions, ILSMP-UMSE showed higher extraction yields of two target compounds than those obtained by reference extraction solvents. Method validation studies also evidenced that ILSMP-UMSE is credible for the preparation of two coumarins from Cortex fraxini. This study is indicative of the proposed procedure that has huge application prospects for the preparation of natural products from plant materials.
研究领域:
植物化学
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天然产物分离
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药用植物学
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DOI
PubMed
高影响因子
Frontiers in Nutrition
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2025
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IF 5.1
Haotian Huang,Xiaobo Zhou,Mengge Sun,Jiajie Chen,Tao Tan,Dongsheng Yang
Introduction: Polysaccharides extracted from the fruits of Phyllanthus emblica L. (PEP) have demonstrated various bioactivities, including antioxidant and prebiotic effects. This study aimed to optimize the extraction of PEP using ultrasonic microwave synergistic extraction (UMSE) and evaluate its bioactivities.Methods: The UMSE process was optimized using response surface methodology (RSM) to identify the most efficient extraction conditions. Antioxidant capacity was evaluated through DPPH, ABTS, and hydroxyl radical scavenging assays, alongside total reducing capacity measurements. For prebiotic activity, the ability of PEP to promote the growth of Lactobacillus casei, Lactobacillus acidophilus, and Lactobacillus plantarum was compared with that of standard prebiotics. Changes in pH and lactic acid production in the culture medium were also monitored.Results: Optimal UMSE parameters included microwave power (370 W), ultrasonic power (340 W), extraction time (25 minutes), and a solid-liquid ratio of 1:6.5 g/mL. These conditions achieved an extraction yield of 8.09%, aligning with the predicted value. The UMSE method showed higher extraction efficiency and sugar content compared to traditional water extraction, with a reduction in impurities. The extracted PEPs exhibited significant scavenging activity against DPPH, ABTS, and hydroxyl radicals, as well as robust total reducing capacity. Additionally, the PEPs demonstrated resistance to hydrolysis by artificial saliva and gastric juice, suggesting their ability to reach the gastrointestinal tract intact. In prebiotic assays, PEP (UMSE-derived, PEP-U) stimulated the proliferation of Lactobacillus spp. more effectively than water-extracted PEP (PEP-W), correlating with increased lactic acid production and reduced pH in the culture medium.Discussion: These results highlight the dual bioactivity of PEP as both an antioxidant and prebiotic, suggesting its potential as a functional food ingredient for promoting gut health and oxidative balance.
研究领域:
食品科学
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生物化学
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药理学
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生物技术
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DOI
PubMed
高影响因子
JOURNAL OF FOOD BIOCHEMISTRY
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2018
·Vol. 42
·期 5
·e12607
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IF 1.552
Zaizhi Liu,Mengxia Wei,Guoqiang Cui,Xinyu Yang,Huiyan Gu,Lei Yang
Double experimental designs, Plackett–Burman design coupled with Box–Behnken design, were used to optimize the simultaneous extraction process of arabinogalactan and taxifolin from Larix gmelinii by ultrasonic microwave synergistic extraction (UMSE) method. The optimal extraction conditions were determined with the extraction yields of 223.40 ± 7.82 mg/g for larch arabinogalactan and 125.02 ± 5.30 mg/g for taxifolin. Compared to conventional methods, UMSE method showed the merits of higher extraction efficiency, saving time, and energy. The molar ratio of galactose to arabinose is found to be 6:1 through the monosaccharide composition analysis of larch arabinogalactan. The obtained taxifolin structure was identified by mass spectrometry, Fourier transform infrared spectroscopy, and nuclear magnetic resonance. Interestingly, larch arabinogalactan and taxifolin showed completely opposite influences on α-amylase, α-glycosidase, and pancreatic lipase; it was inferred that larch arabinogalactan could act as an inhibitor while taxifolin as an accelerator. Practical applications In this study, response surface methodology of Plackett–Burman design and Box–Behnken design performed well to obtain the optimal conditions and satisfactory extraction yields for the extraction of arabinogalactan and taxifolin from Larix gmelinii by ultrasonic microwave synergistic extraction method, which could be a good paradigm for the efficient isolation of bioactive substances from plant matrix in the field of separation science. Meanwhile, the results from the evaluation of the effects of two target compounds on activities of α-amylase, α-glycosidase, and pancreatic lipase in vitro revealed that larch arabinogalactan and taxifolin enjoyed the completely opposite influences on the three digestive enzymes, namely larch arabinogalactan could act as an inhibitor while taxifolin an accelerator. These results will facilitate the application of larch arabinogalactan and taxifolin in the food and pharmaceutical industries.
研究领域:
植物化学
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食品科学
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药理学
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DOI
高影响因子
Food Bioscience
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2024
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IF 4.8
Yifan Ping,Yang Yang,Hongfei Gao,Xiuwei Liu,Jun Pan,Ke Zhang,Huiyan Gu,Hao Tian,Lei Yang
In this study, three different target analytes from the fruit of myrtle ( Rhodomyrtus tomentosa ) were extracted via an enzymatic-homogenate synergistic extraction (EHSE) process, and 10 different aqueous solutions of natural surfactants were selected as extraction solvents, thus enabling the simultaneous extraction of piceatannol, resveratrol, and myricetin from the fruit of myrtle ( Rhodomyrtus tomentosa ). Important factors affecting the yield of piceatannol, resveratrol, and myricetin, including enzyme type, enzyme concentration, pH, surfactant type and dosage, homogenization time, liquid‒solid ratio, incubation and extraction time, incubation time and extraction temperature, were optimized via single-factor experiments. Three important parameters were optimized via the Box‒Behnken design: the liquid‒solid ratio, the incubation–extraction time, and the reaction temperature. The final optimum extraction process conditions were as follows: β-glucosidase concentration, 3.0%, homogenate; time, 3 min; pH, 5; tea saponin concentration, 0.8%; liquid‒solid ratio, 45 mL/g; incubation–extraction time, 2.5 h; and temperature, 67.5 °C. With the optimized experimental parameters, the piceatannol, resveratrol, and myricetin yields were 742.12 ± 37.11 μg/g, 18.58 ± 0.94 μg/g, and 24.83 ± 1.25 μg/g, respectively. Methodological validation and comparison experiments with traditional solvents demonstrated that EHSE is a successful, green, and safe method for extracting active plant components. This approach employs an ecologically benign water-based solution of tea saponin as the extraction solvent, and it combines enzymatic and homogenate procedures to increase extraction efficiency. This study provides a reasonable basis for the application and research of synergistic extraction technology and suggests that more diverse solvent choices should be considered.
研究领域:
化学工程
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食品科学
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植物化学
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生物技术
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DOI
高影响因子
Sustainable Chemistry and Pharmacy
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2025
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IF 5.8
Zhanjun Li,Yunwei Liu,Mingru Kong,Zheng Qin,Qi Shen,Mengze Wang
The primary objective of this study was to achieve high-efficiency, sustainable method for extracting quercetin from Pinus koraiensi s seed scales using a green chitosan–Cu–Fe catalyzed ultrasound–microwave continuous system. Key factors were screened and optimized, with the following optimal conditions: a liquid material ratio of 10:1 mL/g for both ultrasonic and microwave treatments, ultrasonic 10 min, 90 W, 40 °C; microwave irradiation at 303 W for 8.19 min; and exogenous chitosan–Cu–Fe at 0.6 %, achieving an actual yield of 3.13 mg/g. The optimal process was compared with conventional Soxhlet extraction, used as a benchmark to evaluate the new method's efficiency. Kinetic analysis showed equilibrium at 12.5 and 50 min, with yields of 3.33 and 3.23 mg/g, respectively, while prolonged high-temperature exposure extraction caused partial degradation of the extract. Life cycle assessment and inductively coupled plasma mass spectrometry confirmed the superior stability and environmental sustainability of the optimal process. Mechanistic evaluation indicated that the extraction followed a second-order kinetics model; with the second-stage activation energy (87.56 kJ/mol) primarily governed by extraction, indicating that regulating the temperature enhances efficiency and reduces losses. Ultrasonic cavitation and microwave heating enhance extraction efficiency, while chitosan–Cu–Fe improves stability by increasing active sites and facilitating electron transfer. The process offers environmental and sustainability benefits, providing insights into the valorization of forest residues.
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高影响因子
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