IEEE SENSORS JOURNAL
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2024
·
IF 4.3
Tingkuo Chen,Haiming Jiang,Kang Xie,Hongyan Xia
This study aims to develop an advanced glucose sensor based on Single-mode fiber - No-core fiber -Single-mode fiber (SMF-NCF-SMF) microfibers modified with glucose oxidase (GOD) for accurate and simultaneous measurement of glucose concentration and temperature, which could significantly enhance diagnostic capabilities in medical and biological applications. The sensor utilizes the evanescent wave principle to detect glucose concentration and the thermal optical effect to measure temperature. Experimental results demonstrate a concentration sensitivity of 2.07 nm/(mg/mL) within the range of 0-3 mg/mL and a temperature sensitivity of -0.35 nm/°C within the range of 25-50°C. These findings highlight the distinct impacts of concentration and temperature on the interference wavelength. By establishing a demodulation matrix, the sensitivities for both concentration and temperature can be separately determined. In-situ temperature monitoring not only eliminates temperature interference but also ensures that GOD remains at its optimal temperature for maximum activity, thereby enhancing the sensitivity and accuracy of glucose concentration detection. Given its high sensitivity, accuracy, and simplicity, this sensor shows promising potential for widespread use in disease diagnosis and biological detection, paving the way for more advanced diagnostic technologies.
研究领域:
生物医学工程
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光学传感
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医疗诊断
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生物技术
✓ 已验证
产品关联
DOI
高影响因子
Metals
·
2022
·Vol. 12
·期 5
·841
·
IF 2.695
Liang-Liang Zhang,Lin-Jie Zhang,Qing-Jie Yang
Due to its high thermal conductivity and favorable machinability, molybdenum–rhenium (Mo–Re) alloys have huge prospects in the field of high-temperature heat pipes. However, the weldability of Mo–Re alloys has not yet been systematically investigated. Based on an orthogonal test, the influence law of the single-mode fiber laser welding parameters on the weld profile and the mechanical properties of the joints was studied. Furthermore, the existence mode and the distribution law of Re in the fusion zone (FZ) were explored using X-ray photoelectron spectrometer (XPS) and the electron backscattered diffraction (EBSD) system. The results showed that weld penetration and width are most significantly influenced by power, and that these increased with increasing power. The tensile strength of the Mo–Re alloy joints reached 250 MPa, and no obvious hardening was found in the FZ. Re in the FZ also appeared as ReO2, ReO3, and ReC, apart from the atomic state.Keywords:molybdenum–rhenium alloy;single-mode fiber laser;X-ray photoelectron spectrometer;electron backscattered diffraction
研究领域:
材料科学
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焊接工程
✓ 已验证
产品关联
DOI
高影响因子
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES
·
2019
·Vol. 74
·期 10
·931-936
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IF 1.079
Jiahao Yu,Xiaozhan Yang,Wenlin Feng
A hydrogen sulfide (H 2 S) gas sensor based on copper (Cu) nanoparticle deposited graphene oxide (GO) composite membrane with two waist-enlarged tapers is proposed. Three segments of the single-mode fibres (SMFs) are sequentially fused to obtain two waist-enlarged bitapers of Mach–Zehnder interferometer (MZI). When the light of a broadband light source transmits through the first bitaper, some light enters the fiber cladding; the lights of core mode and cladding mode are coupled at the second taper and an MZI is successfully fabricated. The copper/graphene oxide (Cu/GO) composite sensing film is coated on the surface of the second SMF, and the effective refractive index of the coating is changed when the sensitive film adsorbs the target gas. The correlation between the gas concentration and the wavelength shift is achieved and the H 2 S can be measured effectively. The results show that a uniform Cu/GO film is successfully coated on the surface of the fiber, and when the thickness of the sensitive film is about 1.2 μm, the sensor has a sensitivity of 4.42 pm/ppm and a good linearity and selectivity for H 2 S in the range of 0–60 ppm, and the limit of detection is 2.79 ppm. The response time and recovery time are approximately 31 and 48 s, respectively. The sensor has the advantages of small volume, low cost, simple structure, and easy manufacture and so on, which is suitable for on-line monitoring of H 2 S.
研究领域:
光学传感
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材料科学
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环境监测
✓ 已验证
DOI
高影响因子
OPTICS EXPRESS
·
2022
·Vol. 30
·期 24
·42801-42809
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IF 3.833
Guolu Yin,Guolu Yin,Hu Xiao,Hang Zhou,Tao Zhu,Tao Zhu
We propose a distributed pH sensor based on an optical frequency domain reflectometry using a PEGDA-based pH-sensitive hydrogel coated on a single mode fiber. The volume of hydrogel increased as pH value of the surrounding fluid decreased, which converts the pH value to the axial strain in the fiber. Taking capacity of distributed strain measurement with high spatial resolution in optical frequency domain reflectometry, the pH value of the external medium is distributed measured by the wavelength shifts of the local Rayleigh backscattering spectra. The basic hydrogel with different molecular weight was optimized to balance the sensitivity, the response time and also the stability. In the experiment, the range of the pH value from 2 to 6 was measured with a sampling resolution of 1.7 mm, a sensitivity of -199 pm/pH and a response time of 14 min when the hydrogel coating diameter is 2 mm. Such a distributed pH sensing system has a potential to detect and locate some chemical or biological substances in a large-scale environment.
研究领域:
光学传感
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材料科学
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化学传感
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
OPTICAL FIBER TECHNOLOGY
·
2025
·
IF 2.7
Ling Chen,Ruike Liu,Xianfeng Liu,Zhaoyang Li,Guohao Li
A highly economical fiber immunosensor with the harmonic Vernier effect (HVE) is reported for cancer antigen 125 (CA125) tumor marker detection. The sensor architecture is constructed using a special fiber fusion splicer to cascade three sections of single-mode fiber (SMF) in sequence with a large offset. This configuration yields a cascaded Fabry-Perot interferometer (FPI) architecture incorporating the HVE. The misalignment fusion design facilitates direct and seamless interaction between biochemical fluids and optical signals. Experimental results demonstrate that the refractive index sensitivities of the internal envelope and upper envelope reach −5236, and 1163 nm/RIU, respectively, when refractive index increases from 1.334 to 1.339. It has excellent consistency with the simulation results of −5375 nm/RIU and 1257 nm/RIU as refractive index increases from 1.334 to 1.335. Obviously, the refractive index sensitivity is significantly enhanced via the HVE. The designed sensor is further biologically modified with the 50 μg/mL ovarian cancer 125 monoclonal antibody, enabling varying cancer antigen 125 concentrations detection. The proposed biosensor has low detection limit with value of 44.12 fg/mL and a fast response time (<30 min). Therefore, the proposed biosensor has latent application as an ideal platform for disease diagnosis and medical detection.
研究领域:
生物传感器
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生物光子学
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癌症诊断
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光学传感
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光纤技术
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生物医学工程
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免疫传感器
✓ 已验证
产品关联
DOI
高影响因子
OPTICAL FIBER TECHNOLOGY
·
2024
·
IF 2.6
Yuhao Chen,Xiaozhan Yang
A Michelson interference dimethyl methyl phosphate (DMMP) fiber sensor with a single-mode (SMF)-dislocated single-mode (DSMF)-hollow-core fiber (HCF) structure is proposed. To fabricate the Michelson interference structure of SMF-DSMF-HCF, one end of the DSMF was misaligned and fused to the SMF, the other end was fused to the HCF to generate a reflective surface. The structure, elemental composition, and surface morphology of ZIF-8@Ag were analyzed using X-ray diffraction, X-ray photoelectron spectroscopy, and scanning electron microscopy after the ZIF-8@Ag/PDDA composite was coated on the surface of DSMF. The result shows that the sensitivity and the detection limit of the sensor are 45.71 dB/ppm and 0.1431 ppb, respectively, and the response/recovery time is around 14/12 s. The sensor also has excellent selectivity and stability.
研究领域:
光学工程
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传感器技术
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材料科学
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化学传感
✓ 已验证
产品关联
DOI
高影响因子
OPTICAL FIBER TECHNOLOGY
·
2022
·
IF 2.8
Zizheng Yue,Luqiao Feng,Wenlin Feng
In this work, a novel Michelson interferometer (MI) based on the core-offset splicing between the single-mode fiber (SMF) and thin-core fiber (TCF) is proposed and experimentally demonstrated. By using the layer-by-layer self-assembly method, a novel metal-organic framework UiO-66 film is coated on the TCF surface. Then, the MI for fluoride-ion detection is obtained. The adsorption of fluoride ions by the sensing film induces the change in the effective refractive index (RI) of the coated cladding, which results in the regular redshifts of the interference dip. Different fluoride-ion concentrations can be obtained in real-time by monitoring the dip wavelength shifts. The proposed sensor exhibits an excellent linear response in the fluoride-ion concentration range up to 0.1 ppb, a high sensitivity of 612 pm/ppb and a fast response time of 10 s.
研究领域:
光学传感
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材料科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
MEASUREMENT SCIENCE and TECHNOLOGY
·
2021
·Vol. 33
·期 3
·035102
·
IF 2.046
Sijie He,Yushan Liu,Wenlin Feng,Bangxing Li,Xiaozhan Yang,Xinyue Huang
A carbon monoxide (CO) sensor based on a Michelson interferometer combined with α-Fe2O3/reduced graphene oxide quantum dots (rGOQDs) composite film is proposed and fabricated. First, a waist-enlarged taper is formed between the single-mode fiber (SMF) and the no-core fiber (NCF), then the other end of the NCF is spliced with a section of thin-core fiber (TCF). The end of the TCF is coated with a layer of silver film to enhance the reflection. Thus, a Michelson interferometer comprising SMF–NCF–TCF is formed. The α-Fe2O3/rGOQDs composite film is deposited on the outside surface of the TCF. The specific adsorption of CO by the composite film leads to a change in the sensor's effective refractive index, realizing the detection of CO. The results show that the interference intensity of the monitoring valley decreases with increase in the concentration of CO. The sensitivity of the sensor is 0.057 dBm ppm−1, the detection limit of the sensor is 105 ppb and the response time and recovery time are 70 s and 100 s, respectively. The sensor has the advantages of high sensitivity, high selectivity and simple structure, and it is expected to be used for the detection of low concentrations of CO gas.
研究领域:
光学
·
材料科学
·
传感器
·
气体检测
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）