Small Methods
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2021
·Vol. 5
·期 6
·2100202
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IF 14.188
Tiantian Dai,Zanhong Deng,Xiaodong Fang,Huadong Lu,Yong He,Junqing Chang,Shimao Wang,Nengwei Zhu,Liang Li,Gang Meng
Seeking a facile approach to directly assemble bridged metal oxide nanowires on substrates with predefined electrodes without the need for complex postsynthesis alignment and/or device procedures will bridge the gap between fundamental research and practical applications for diverse biochemical sensing, electronic, optoelectronic, and energy storage devices. Herein, regularly bridged CuO microhemisphere nanowire arrays (RB-MNAs) are rationally designed on indium tin oxide electrodes via thermal oxidation of ordered Cu microhemisphere arrays obtained by solid-state dewetting of patterned Ag/Cu/Ag films. Both the position and spacing of CuO microhemisphere nanowires can be well controlled by as-used shadow mask and the thickness of Cu film, which allows homogeneous manipulation of the bridging of adjacent nanowires grown from neighboring CuO hemispheres, and thus benefits highly sensitive trimethylamine (TMA) sensors and broad band (UV–visible to infrared) photodetectors. The electrical response of 3.62 toward 100 ppm TMA is comparable to that of state-of-the-art CuO-based sensors. Together with the feasibility of in situ assembly of RB-MNAs device arrays via common lithographic technologies, this work promises commercial device applications of CuO nanowires.
研究领域:
材料科学
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传感器技术
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纳米技术
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
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2020
·
IF 5.006
Xiaoling Wu,Shuli Liu,Jun Xiong,Bin Chen,Min-Hua Zong,Ji-Guo Yang,Wen-Yong Lou
The integration of chemical catalyst and biocatalyst is of great interest due to the accompanying high designability of chemo-enzymatic cascade reactions for sustainable catalytic processes in chemical engineering. Here, a facile strategy is proposed by preparation of a copper ions coordinated cytidine monophosphate (CMP) encapsulated lipase composite via in-situ assembly in aqueous solution which followed by reduction to obtain an enzyme-copper hybrid catalyst. The as-synthesized enzyme-copper nucleotide composite exhibited both high enzymatic activity (6.05 U/mg) and copper-catalytic activity (with reaction rate constant of 8.85 min −1 ) in the chemo-enzymatic cascade reaction for hydrolysis of p -nitrophenyl butyrate ( p -NPB) and generation of p -aminophenol ( p -AP), which is a pharmaceutical intermediate for production of analgesics and antipyretics. This study thus sheds light on fabrication of hybrid catalyst under facile conditions, exhibiting potential in development of biosensors, industrial catalysis and biomanufacturing.
研究领域:
生物化学
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化学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2024
·
IF 20.2
Jinghe Bai,Defeng Zhou,Leilei Niu,Xiaofei Zhu,Ning Wang,Qingwen Liang,Youjie Zhang,Ling Hu,Huifang Gong,Wenfu Yan
Here, in situ assembly in La 0.6 Sr 0.4 Co 0.2 Fe 0.8 O 3-δ and CoFe 2 O 4 composite (LSCFC) cathode was induced by Pr to form La 0.6 Sr 0.4 Co x Fe y O 3-δ /PrCoO 3 /Co 3 O 4 /PrO 2 (LSCFC-PI) multiphase heterostructures . The surface of LSCFC-PI forms uniform nanoparticles , and the unique core-shell structure prevents Sr segregation, thereby enhancing CO 2 tolerance and increasing oxygen reduction reaction (ORR) active sites. Furthermore, compared with LSCFC, LSCFC-PI increases the oxygen vacancy content of the cathode due to the existence of multiphase heterostructure, improves the ORR kinetics, and the conductivity is also greatly improved. The peak power density (PPD) of LSCFC-PI as a single-cell cathode at 700 ℃ reached 1.51 W cm −2 , which was 2.65 times higher than that of LSCFC's 0.57 W cm −2 , and in the long-term stability test at a constant voltage ∼0.8 V for 100 hours, showing excellent stability. In situ assembly of multiphase heterostructures is expected to become a new strategy for developing high-performance IT-SOFC cathodes.
研究领域:
材料科学
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能源科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2020
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IF 8.758
Haiyan Gao,Chengchao Chu,Yi Cheng,Yang Zhang,Xin Pang,Dengfeng Li,Xiaoyong Wang,En Ren,Fengfei Xie,Yan Bai,Lijuan Chen,Gang Liu,Meiyun Wang
Glioblastoma is one of the most lethal cancers and needs effective therapeutics. The development of coordination-driven metal–organic nanoassemblies, which can cross the blood–brain barrier (BBB) and blood–brain tumor barrier (BBTB) and have multiple desired functions, may provide a promising solution to this issue. Here, we report an in situ assembled nanoplatform based on RGD peptide-modified bisulfite-zincII-dipicolylamine-Arg-Gly-Asp (Bis(DPA-Zn)-RGD) and ultrasmall Au-ICG nanoparticles. Attributed to its positive charges and neovascular targeting properties, Bis(DPA-Zn)-RGD can be selectively delivered to the tumor site, and then assembled in situ into large nanoclusters with subsequently administered Au-ICG nanoparticles. Au nanoparticles with ultrasmall size (∼7 nm) can successfully cross the BBB. The obtained nanoclusters exhibit strong near-infrared-red (NIR) absorption and an enhanced tumor retention effect, enabling precise orthotopic fluorescence/photoacoustic imaging. With the aid of image guidance, the photothermal effect of the nanoclusters is observed to suppress tumor progression with the inhibition efficiency reaching up to 93.9%. Meanwhile, no photothermal damage can be found for normal brain tissues. These results, herein, suggest a feasible nanotheranostic agent with the ability to overcome the BBB and BBTB for imaging and therapy of orthotopic brain tumors.
研究领域:
癌症研究
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纳米医学
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神经科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2025
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IF 4.7
Yu-Teng Zhang,Jing- Yu Sun,Jian Li,De-Sheng Wei,Wan-Yi Lan,Nan Lv,Shuang-Bao Li
This study reports one-pot microwave-assisted solvothermal synthesis of Ti-Zr bimetallic organic cages (TiZrT-BTC-α, where α denotes the actual Ti molar percentage and T represents the tetrahedral cage structure). The reaction employed zirconocene dichloride (Cp 2 ZrCl 2 , Cp = η 5 -C 5 H 5 ), titanocene dichloride (Cp 2 TiCl 2 ) and 1,3,5-benzenetricarboxylic acid (H 3 BTC) as solid precursors to form a V 4 F 4 (V = vertex and F = face) coordination tetrahedron. The presence of the characteristic Ti-O vibration band at 420 cm -1 in the FT-IR spectrum, along with the characteristic Ti 4+ band signal at 458.6 eV in the XPS spectrum, collectively demonstrates the successful incorporation of titanium into the molecular cage structure. Notably, the introduction of titanium endowed the material with visible light absorption capability and modulates its electronic structure, reducing the band gap value from 3.73 eV (ZrT-BTC) to 2.48 eV (TiZrT-BTC-7.9). The photocatalytic activities of TiZrT-BTC-α were evaluated using tetracycline hydrochloride (TC) as a target pollutant under visible light illumination. Among the series, TiZrT-BTC-7.9 demonstrated excellent photocatalytic activity, achieving 92.17% degradation efficiency for TC (20 mg/L) within 3 hours. Electron spin resonance (ESR) spectroscopy combined with radical trapping experiments identified superoxide radicals (·O 2 - ) served as the dominant reactive species. This work paves the way for developing cage-based photocatalysts with tunable optoelectronic properties.
研究领域:
材料化学
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环境催化
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配位化学
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纳米功能材料
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光化学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2019
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IF 4.916
Yi Fen Xie,Meng Li Liu,Wen Yi Lv,Xue Li,Peng Fei Gao,Yuan Fang Li,Cheng Zhi Huang
Developing rapid, sensitive and intelligent optical probes is important for the growing need of microscope imaging analysis. Herein, we proposed a new strategy to assemble plasmonic nanoprobes in situ for dark-field microscopy imaging scatterometry by making use of the formation, disruption, and re-formation of cytosine-Ag + -cytosine (C Ag + C) bonds. The C Ag + C bond was formed at first through Ag + -mediated base pairing between C-contained aptamer and its C-mismatched complementary DNA. Owing to the subsequent binding of target with the aptamer, the C Ag + C structure was disrupted, leading Ag + to be quantitatively released. The released Ag + ions can make the C Ag + C bonds formed again between the C-contained sequence that modified gold nanospheres (AuNSs), and AuNS clusters thus formed in situ, which have strong plasmonic scattering signals owing to the coupling of localized surface plasmon resonance (LSPR). Therefore, the plasmonic scattering signals enhanced following the off-on mode under the dark field microscope from the ‘zero’ background to on . As a concept of proof, sensitive detections for Aflatoxin B1 (AFB 1 ) in foods, carcinoembryonic antigen (CEA) in blood serum, and Ricin B in artificial sample, was successfully made by using of the in situ formed AuNS clusters, demonstrating that the newly developed metal-mediated strategy for assembling nanoprobes are universal.
研究领域:
光学成像
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纳米技术
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分析化学
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2018
·
IF 6.578
Xueting Zhao,Ning Jia,Lijuan Cheng,Lifen Liu,Congjie Gao
Metal-polyphenol coordination networks have been actively explored as a facile, rapid and green platform for developing materials. In this study, novel antifouling hybrid membranes are successfully prepared via in situ assembling metal-polyphenol coordination networks and are proposed for oil/water separation application. Based on the coordination-driven cross-linking and assembling of Ti IV and TA within polyvinylidene fluoride (PVDF) membrane matrix, TA-Ti coordination networks are successfully introduced and uniformly distributed in the as-prepared PVDF/TA-Ti membranes. The effects of the embedded TA-Ti coordination networks on both surface morphologies and pore structures of PVDF/TA-Ti membranes are investigated. The surface chemical compositions of PVDF/TA-Ti membranes are analyzed by energy-dispersive X-ray (EDX) and Fourier transform infrared spectroscopy (FTIR). The water contact angle analysis and DSC study on bound water content reveal the outstanding hydration capability of PVDF/TA-Ti membranes, indicating the higher underwater superoleophobicity and antifouling property of PVDF/TA-Ti membranes. The as-prepared PVDF/TA-Ti membranes exhibit remarkably improved antifouling performance with the flux recover ability increased to a maximum level about 100% for the filtration of oil-in-water emulsions. Overall, this study highlights the promising antifouling potential of TA-Ti coordination networks in designing antifouling membranes, and proposes a facile in situ hybridization method for preparing antifouling membranes derived from versatile metal-polyphenol coordination networks.
研究领域:
材料科学
·
化学工程
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
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