SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Gangan Wang,Chaoyi Chen,Junqi Li,Xin Lin,Haonan Zheng
Calcium-silica slag (CSS) is a highly alkaline residue, rich in calcium, generated during the chemical pre-desilication process of medium- and low-grade bauxite. Mismanagement of CSS can result in detrimental environmental impacts. This study developed a novel method that combines CO 2 sequestration with CSS utilization, thereby achieving simultaneous dual-value enhancement of CSS and eliminating waste discharge. Under optimized Ca 2+ leaching and carbonation conditions, a remarkable Ca 2+ extraction efficiency of 96.93 % was attained, while the carbonation efficiency reached 99.37 %. Consequently, this process sequestered 301.7 kg of CO 2 per ton of CSS. The leaching process of Ca 2+ in NH 4 Ac solution was realized based on the unreacted shrinking core model, which accounts for internal diffusion and chemical reaction as factors influencing leaching. The resulting carbonated product exhibited outstanding characteristics: high-purity vaterite composed of 97.43 wt% CaCO 3 with a whiteness level of 95.2 %. By regulating the carbonation temperature, the crystal particulate size distribution of CaCO 3 was tailored to meet specific requirements for various applications. Furthermore, silicon content was enriched in the leaching residue, increasing the effective SiO 2 content from 25.2 wt% to 53.12 wt% and reducing the pH from 12.23 to 7.34, rendering it a suitable silica fertilizer for agricultural production.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Weimin Chen,Min Luo,Kai Yang,Xiaoyan Zhou
Searching for a sustainable precursor that is capable of absorbing microwave energy is crucial for its rapid conversion into porous carbon via microwave heating. Here, alginate-based hydrogel beads cross-linked by bivalent ions (Cu 2+ , Zn 2+ , and Ca 2+ ) are converted into porous carbons (SPCs) in 10 min by applying simple microwave-assisted pyrolysis . Water wrapped in hydrogel beads and bivalent ions serve as initial microwave absorbers to convert alginate into char which acts as a good microwave absorber in the following stages. Additionally, bivalent ions also act as a gelling agent to generate hydrogel beads, as a porogen to obtain a highly porous structure, and as a metal donor to form the SPC/Cu composite. The resultant SPC has a high specific surface area of 1336 m 2 g −1 , a large total pore volume of 0.56 cm 3 g −1 , interconnected macropores, as well as a high oxygen content of up to 13.2%. These attractive characteristics give SPC a remarkable rate capability of 72% at 50 A g −1 . Interestingly, the interconnected macropores in SPC offer sufficient space for Cu growth via the redox reactions of Cu 2+ ; thus, the SPC/Cu composite without acid wash shows a specific capacitance as high as 804 F g −1 at 0.5 A g −1 .
研究领域:
材料科学
·
能源工程
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Le Wang,Xiaohong Pan,Shuzhi Tang,Yaqi Wang,Haixing Shi,Huanhuan Wang,Wenzhen Liu,Zhuo Chen
The skin microbiota is an inseparable component of the skin barrier structure, which participates in the stabilization or impairment of the barrier function as well as the development of many skin diseases. In order to maintain the stability of skin bacteria community structure, people pay more and more attention to protecting probiotics, such as bacilli, and killing pathogens, such as Gram-positive cocci. We herein report a negatively charged photosensitizer TPA-3NBA with aggregation-induced emission (AIE) characteristics, which was synthesized by one-step reaction, can selectively and rapidly stain (within 0.5 min) and effectively kill Gram-positive cocci (killing 6.0 log 10 of Staphylococcus aureus at a concentration of 1 μM) without affecting bacilli under white light irradiation. This selective bacterial imaging makes it possible to quickly identify locally bacterial infection. Furthermore, the normal concentration of divalent ion (Ca 2+ ) in human body can significantly promote the absorption of TPA-3NBA by Gram-positive cocci, thus improving its antibacterial activity. To the best of our knowledge, this is the first photosensitizer to be reported with good performance in selective bacterial imaging and removal of Gram-positive pathogenic cocci, indicating its potential application prospect in targeted antimicrobial therapy.
研究领域:
微生物学
·
药理学
·
皮肤病学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Xin Zhang,Xu Zhang,Lushen Xu,Guoliang Zhang,Qin Meng
High-quality thin-film composite (TFC) membranes with high selectivity and permeability have great significance owing to their practical applications, specifically for the accurate differentiation of monovalent and divalent ions. However, the trade-off effect between selectivity and permeability is still a big challenge due to the difficult structure adjustment of the selective layer. Herein, polydopamine (PDA) functionalized with a hydrophobic long alkane chain was first explored as a functional amphiphilic interlayer to synthesize high-quality TFC membranes via a confined interfacial polymerization (IP) reaction. The amphiphilic interlayer not only restricted the formation of the polyamide (PA) matrix in the pores of the substrate but also accelerated spatially more homogeneous polymerization and formed a PA active layer with a more uniform pore size distribution. The method may provide an effective principle for the construction of versatile polyamide-based membranes with high perm-selectivity on various supports. The NaCl/Na2SO4 separation factor of the D-8/PA membrane reached as high as 204.07, while the flux increased up to 25.71 L m–2 h–1 bar–1. This progress provides a more feasible way for the construction of high-quality TFC membranes with a devisable and creative amphiphilic interlayer for industrial application.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 24
·2000
·
IF 4.4
Zhipeng Yu,Pengxu Yan,Yilei Sheng,Chengwei Zhang,Zhun Qiao,Qikui Fan,Chuncai Kong,Zhimao Yang
Copper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu+/Cu2+interfaces within dual-valence copper nanostructures to achieve enhanced sensitivity in glucose sensing. By employing a hydrolysis method to tune Cu2+/Cu+ratios precisely, we achieved an optimal electrochemical interface with heightened stability and reactivity. The Cu+/Cu2+interface-based flexible electrode demonstrated excellent glucose sensitivity (332.4 µA mmol/L−1cm−2at +0.65 V), wide linear range (up to 10 mmol), a low detection limit of 1.02 nmol/L, and strong selectivity, including detection in human sweat, making this study significant for advanced electrochemical sensors.
研究领域:
材料科学
·
生物医学工程
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nano Today
·
2020
·
IF 16.907
Ling Li,Xiaopeng Guo,Xiaole Peng,Hongsen Zhang,Yiming Liu,Han Li,Xiaojun He,Dingwen Shi,Bin Xiong,Yanbing Zhao,Chuansheng Zheng,Xiangliang Yang
Interventional cancer therapy, till date, experiences a major challenge to improve the synergistic effect of radiofrequency ablation (RFA) and trans-artery embolization (TAE). Here, RF-responsive dual-valent gold nanoclusters ( dv GC@PNAs), as multifunctional blood-vessel-embolic agents, have been successfully manufactured for comprehensive interventional theranostics of solid tumors. Distinct RF-induced heating effect was obtained by reducing Au(I)-thiolate complex using l -glutathione under the template polymer of temperature-sensitive poly( N -isopropylamide- co -acrylic acid) (PNAs), the well-defined dv GC@PNAs with the core-shell nanostructure of Au(0) atoms surrounded by a high content of Au(I) ions, thereby triggering cell apoptosis, necrosis, and metastasis inhibition. Efficient TAE cancer therapy can also be achieved by rapid diffusion of dv GC@PNAs into tumor peripheral arteries that impede tumor blood supply by their favorable temperature-sensitive sol-gel transition. The immunofluorescent analyses substantiated the greatly improved tumor microenvironment post TAE procedure, owing to the radiofrequency-responsive dv GC@PNAs, induced a favorable immune response, thereby augmenting the synergistic antitumor effect of RFA and TAE. The present study provides a valuable paradigm for ameliorating the synergistic interventional therapies by the rational design of RF-responsive metal nanoclusters.
研究领域:
生物医学工程
·
肿瘤学
·
纳米医学
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Junbin Liao,Quan Chen,Nengxiu Pan,Xinyan Yu,Xing Gao,Jiangnan Shen,Congjie Gao
It is of significant importance to develop highly monovalent anion-selective membranes (MASM) having stable structure for a wide range of applications. To realize the efficient monovalent/bivalent anion separation, in this work, three amphoteric ion-exchange membranes (AIEMs) through blending were fabricated for use in electrodialysis (ED). The three membranes were prepared by blending amino-containing poly(arylene ether sulfone) (PAES-NH 2 ) with 10, 15, and 20 wt% of sulfonated polysulfone (SPSf), respectively, followed by grafting imidazolium salt-terminated side alkyl chains on PAES backbone. Our investigations demonstrate that each transparent AIEM shows good miscibility between the two components, which has been verified by a homogeneous structure via SEM observation and by an even distribution of N element via EDX mapping. In the ED process at a current density of 2.5 mA cm −2 , AIEM with 15 wt% of SPSf shows the superior perm-selectivity (Cl – /SO 4 2– ) of 21.8, relative to many reported MASMs having modified surfaces (<6.0), which is synergistically contributed by (i) electrostatic repulsion difference from the negatively-charged sulfonate groups against monovalent Cl – ions and bivalent SO 4 2– ions and (ii) hydrated energy difference of hydrated Cl – /SO 4 2– ions. This work thus presents a strategy to guide the architectural design of advanced MASMs.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2024
·
IF 3.8
Zilong Zhang,Jiahuan Chen,Lixiang Chen,Kaihua Long,Lejing Qu,Silin Huang,Xinyi Yuan,Xu Ji,Qian Li,Xinfeng Zhao
Functional protein immobilization forms the basis for bio-detections. A series of one-point, site-specific immobilization methods have been developed, however, it still remains as a challenge how to avoid the proteins to move in all directions as well as conveniently regenerate the bio-devices. Herein, we have developed a bivalent affinity binding-inspired method for PPARγ immobilization using DNA aptamer and nickel-nitrilotriacetic acid (Ni 2+ -NTA) chelation. The specific DNA aptamer ( Apt 2 ) was selected by an on-column systematic evolution of ligands by exponential enrichment (SELEX) method with affinity of (1.57 ± 0.15) × 10 5 M −1 , determined by isothermal titration calorimetry (ITC). Apt 2 and nickel-nitrilotriacetic acid (Ni 2+ -NTA) were modified on macroporous silica gels via L-α-allylglycine as a linker. They respectively interacted with PPARγ and 6×His tag via bivalent affinity binding for the receptor immobilization. After comprehensive surface characterization, PPARγ was proved to be successful immobilized. Chromatographic studies revealed that the immobilized PPARγ has conformation selectivity, which discriminated agonist and antagonist of the receptor. Ligand-binding parameters (affinity and rate constant) of four agonists (rosiglitazone, pioglitazone, troglitazone, and magnolol) with PPARγ were determined. Troglitazone showed the lowest dissociation rate constant. The binding affinities (3.28 × 10 7 , 1.91 × 10 6 , 2.25 × 10 7 , and 2.43 × 10 7 M −1 ) were highly consistent with the data obtained using purified receptor in solution (2.16 × 10 7 , 4.52 × 10 6 , 1.20 × 10 7 , and 1.56 × 10 7 M −1 ), offering reliable bio-detection method for PPARγ and its ligands. Due to the biocompatibility of nuclear receptor with DNA, it is conceivable that the bivalent affinity-based method will be a general method for the immobilization of other nuclear receptors, which may provide selective conformation and improved ligand-binding activity for the receptors.
研究领域:
生物化学
·
分子生物学
·
生物技术
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Junbin Liao,Qishun Zhang,Yu Xu,Shiyu Zhou,Yifan Xu,Wenlong Ding,Zhiqiang Wu,Haoyu Liu,Yanqing Xu,Huimin Ruan,Jiangnan Shen
The ion separation performance of polymer membrane can be significantly enhanced by constructing suitable and stable ion channels within the dense matrix. In this work, we fabricated four anion exchange membranes (AEMs) based on a type of distorted poly(aryl ether sulfone) bearing dual-side-chains and explored the influence of these dual-side-chains by tuning the ratio of the two on the separation performance of Cl−/F− and Cl−/SO42−. Small-angle X-ray scattering analysis indicated that the as-prepared AEMs in wet state possessed sub-nanometer ion channels with a size of 0.334 nm, which resulted from the synergetic modification of the distorted main chains and dual-side-chains. In addition, the stability of the ion channels could be verified by a very low swelling ratio of 5.3%. The AEM with the smallest ion channel demonstrated superior perm-selectivity (Cl−/SO42−) of 52.21 during the electrodialysis (ED) process, compared to other AEMs, such as ACS AEM, which showed a selectivity of 18.63. In addition, the optimum AEM (PPH-sIm10−X-5NX) also exhibited selectivity for Cl−/F− due to its dense structure and hydrophobic side chains. By using free volume and electrostatics-driven simulations, it was inferred that the ion-blocking effect of the dense membrane structure on the transport of larger ions was effective. As a result, this dual-side-chain polymer with a distorted backbone is conducive to constructing stable sub-nanometer ion channels in AEMs for mono-/bi-valent anion resource recovery.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Jingjing Gu,Jiu Yang,Qinshan Zhu,Zongliang Wan,Ziqiang Hong,Xingyun Li,Ruonan Tan,Suixin Zhang,Rui Jia,Zheng Ji,Cen-feng Fu,Jin Ran,Peipei Zuo,Peng Cui
Anion exchange membranes (AEMs) that enable effective mono-/divalent anion separation are highly desired for many environment-related applications. Conventional AEMs are characterized with microphase-separated microstructures and rely on the electrostatic attraction between anions and positively charged elements within hydrophilic regions to selectively transport anions. Sufficient charged groups are usually required to ensure high anion permeability, but the stronger interaction encountered by divalent anions than that by monovalent anions results in very low selectivity. We here propose a shielding effect-based strategy, that is, simply mixing piperidinium-based AEMs with carboxylated graphene quantum dots (GQD). These negatively charged GQD can electrostatically interact with the polymer matrix, thereby enhancing the connectivity of hydrophilic regions and also leading to an obvious shielding effect which causes a larger decrease in electrostatic attraction for divalent anions than that for monovalent anions. With the introduction of GQD, the resulting AEMs show obvious enhancement in both anion permeability and anion selectivity, with a Cl - transport rate of 3.2 mol m -2 h -1 and a Cl - /SO 4 2- selectivity of 21.8 (8 times of the commercial ACS, 5 times of the original AEMs without GQD), and exceed other reported microphase-separated polymer membranes. This work offers a simple and promising strategy for high-performance ion-selective membranes.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2025
·
IF 5.1
Xinhan Chen,Gaofan Chen,Ya-Nan Feng,Lizhen Zhang,Yan Yu,Lingyun Li
Developing single-component white-light phosphors remains challenging due to the difficulty in achieving dual emission from mixed-valent activators. Herein, we present a carbon-modulated reduction synthesis (CARS) method to fabricate Eu2+/Eu3+ co-doped La3Si2O8Cl (LSOCl) phosphors without requiring hazardous reducing atmospheres. By modulating carbon content (Eu : C = 1 : 0–2.4), the Eu2+/Eu3+ ratio is effectively controlled, enabling tunable emission from pink to white and yellow under 365 nm UV excitation. The optimized LSOCl:7%Eu (Eu : C = 1 : 1.9) exhibits broadband emission (390–720 nm) with a high color rendering index (Ra = 85.05), cool white light (5489 K, CIE: 0.33, 0.38), and stable performance under varying currents. Additionally, LSOCl:7%Eu (Eu : C = 1 : 1.4) shows excitation-dependent chromaticity shifts: minimal changes under solar-blind UV (250–280 nm) but dramatic variations at 280–350 nm, facilitating rapid detection. A solar-blind UV detector was designed, demonstrating fast response, high resolution (50% CIE shift at 330 nm), and anti-interference capability. The CARS method offers an eco-friendly, scalable route for dual-emission phosphors, showcasing their dual utility in high-quality white LEDs and sensitive UV detection technologies.
研究领域:
材料科学
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Lian Xia,Jia Zheng,Jian Su,Yue Tang,Zhen Wu,Xiaojuan Niu,Yuangen Wu
Amygdalin, a cyanogenic glycoside abundant in apricot kernels, poses a food safety risk, requiring rapid detection that conventional chromatographic methods cannot fulfill for on-site application. Thus, this study aims to construct a novel colorimetric sensing platform and improve detection performance through a multivalent aptamer strategy. This pioneering work introduces a novel bivalent aptamer strategy for ultra-sensitive on-site amygdalin detection. The aptamers specific to amygdalin were screened using a five-segment single-stranded DNA library and Capture-SELEX, with truncated variants optimized to obtain a high-affinity core sequence. A key innovation involves the first design and synthesis of a bivalent aptamer that exploits synergistic binding to enhance target affinity. The bivalent aptamer (Bapt 4-4) exhibited doubled affinity for amygdalin compared to its monovalent truncated counterpart (Amyg 4–26), achieving a dissociation constant ( K d ) of (2.19 ± 1.03) nM. By integrating the bivalent aptamer with the laccase-like activity of silver oxide nanoparticles (Ag 2 O NPs), an aptasensor with high sensitivity and specificity was developed, yielding a detection limit of 0.008 μg mL −1 , which is lower than that of the monovalent aptamer-based sensor (0.0137 μg mL −1 ). This multivalent aptamer strategy provides an effective approach for highly sensitive amygdalin detection. Furthermore, the constructed bivalent aptasensor provides a robust technical tool for the on-site monitoring of plant-derived cyanogenic glycoside toxins, with broad application prospects in the domains of food safety and traditional Chinese medicine safety.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）