SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2023
·
IF 4.4
Wenqian Li,Dongsheng Zhao,Wencui Li,Rongmei Wen,Xin Liu,Liying Liu,Ting Li,Liming Fan
By taking advantages of confinement effect can effectively prevent dye aggregation caused luminescent quenching, Eosin Y (EY) was encapsulated into a chemorobust porous CoMOF as secondary fluorescent signal to construct the dual-emitting sensor of EY@CoMOF. And the photo-induced electron transfer from CoMOF to EY molecules induced EY@CoMOF presenting a weak blue emission at 421 nm and a strong yellow emission at 565 nm. Those dual-emission features also endow EY@CoMOF itself great potentials as a self-calibrating ratiometric sensor in visually and efficiently monitoring hippuric acid (HA) in urine, with fast response, high sensitivity and selectivity, excellent recyclable, and low LOD (0.24 μg/mL). Furthermore, based on a tandem combinational logic gate, an intelligent detection system was designed to improve the practicability and convenience of HA detection in urine. To the best of our knowledge, this is the first example of dye@MOF based sensor for HA detection. And this work provides a promising approach for developing dye@MOF based sensors to intelligent detect bioactive molecules.
研究领域:
化学传感器
·
生物医学检测
·
材料科学
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产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2023
·
IF 4.6
Dongsheng Zhao,Wenqian Li,Rongmei Wen,Nana Lei,Wencui Li,Xin Liu,Xiutang Zhang,Liming Fan
With the introduction of Eu3+ ions as the secondary fluorescent signal reporter and sensing active sites, a dual-emission ratiometric sensor of Eu3+@NiMOF (Eu3+ functional NiMOF) for hippuric acid (HA) detection in urine and serum was fabricated via the postsynthetic encapsulating strategy. Based on the two emission signals at 441 nm (turn-on) and 628 nm (turn-off), the produced Eu3+@NiMOF ratiometric sensor provided enhanced sensitivity, higher selectivity, and 9.7 times lower limits of detection (LOD) for the detection of HA (2.38 μM, 0.42 μg·mL–1) than that of the pristine NiMOF. Considering the high sensitivity and visualization results, further exploration of intelligent applications in the HA sensing process was carried out by constructing a tandem combinational logic gate to improve the practicability and convenience with the help of a smartphone. This work provides a promising approach for developing MOF-based ratiometric sensors to detect biomarkers.
研究领域:
生物传感
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材料科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Wenting Li,Xinai Zhang,Xuetao Hu,Yongqiang Shi,Zhihua Li,Xiaowei Huang,Wen Zhang,Di Zhang,Xiaobo Zou,Jiyong Shi
A novel fluorescence sensing platform was fabricated for visual detection of cadmium ions (Cd 2+ ) with excellent stability and portability. In this protocol, dual-emission ratiometric fluorescence probe were constructed based on silicon oxide-coated copper nanoclusters (CuNCs@SiO 2 ) as a signal reference and cadmium telluride quantum dots (CdTe QDs) as signal response, thereby greatly improving the accuracy of test results. The level of Cd 2+ can be reported within a wide linear range from 0.010 mg·L −1 to 2.0 mg·L −1 with a sensitive detection limit of 1.1 μg·L −1 (2.75 μg·kg −1 ) and a quick sample-to-answer monitoring time of 6 min, which was quite qualified for regularly monitoring Cd 2+ . Moreover, aiming to attain portable analysis, the smartphone as colorimetric reader and analyzer were also utilized for rapidly analyzing Cd 2+ by capturing the change in fluorescence color. Additionally, benefiting from the strong combination of 1, 10-phenanthroline (Phen) and Cd 2+ , the fluorescence probe showed excellent anti-interference activities for Cd 2+ assay in complex oyster matrix. Overall, the sensing platform had significant stability, specificity and sensitivity, offering a promising potential for conveniently evaluating the quality of marine bivalves polluted with Cd 2+ .
研究领域:
分析化学
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环境科学
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生物技术
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Yue Yang,Qunyan Wei,Tong Zou,Yulin Kong,Linfeng Su,Dian Ma,Yude Wang
Developing dinotefuran (DNF) sensing probe is crucial for the monitoring of DNF residues. A dual-emission ratiometric fluorescent probe of sulfur-doped carbon quantum dots (S-CQDs) and copper nanoclusters (CuNCs) hybrid (S-CQDs/CuNCs) were developed for sensitive and selective detection of DNF. The fluorescent signals of CuNCs were quenched in the presence of DNF, while the fluorescent signals of S-CQDs enhanced after the addition of DNF. The ratiometric fluorescent performance of as-developed probe was mainly based on the inner filter effect (IFE) between S-CQDs and CuNCs. Interestingly, the aggregation of CuNCs occurred after the addition of DNF, reducing the IFE effect between S-CQDs and CuNCs, leading to the fluorescent intensity of S-CQDs recovered and CuNCs fluorescence decayed. The ratiometric fluorescent performance of S-CQDs/CuNCs illustrated a good sensitivity and selectivity ranging from 10 μM and 500 μM, with a low detection limit of 7.04 μM. Importantly, real samples investigations implied the good application potential of S-CQDs/CuNCs in DNF monitoring.
研究领域:
分析化学
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环境科学
✓ 已验证
DOI
高影响因子
Materials Advances
·
2021
·Vol. 2
·期 10
·3346-3352
·
IF 0
Ying Li,Dan Liu,Ya-Qi Wang,Fang-Fang Wang,Han-Xun Qiu
In this study, we developed a novel flexible method to construct a lanthanide dual-emitting ratiometric fluorescence nanoprobe with excellent luminescence properties and significant selectivity for the detection of copper ions, where the central Eu3+ ions are coordinated with 2,6-pyridinedicarboxylic acid (DPA) on the surface of CQDs. The structure and chemical sensing photoluminescence properties of the as-prepared fluorescent probe have been investigated in detail. Moreover, the results have shown that Eu-DPA–CQDs exhibit two fluorescence emissions at 450 nm and 613 nm, respectively, under an excitation wavelength of 285 nm. The responses of the two emissions towards Cu2+ ions are completely different and can provide references for each other. Therefore, it can be designed as a fluorescence sensor for the detection of Cu2+ ions. The emission spectrum at 613 nm is markedly quenched, while that at 450 nm slightly changed after the addition of Cu2+ ions. When the Cu2+ ion concentration was 0–150 μM, the FL ratio (IEu/ICQDs) showed a good linear relationship with the lowest detection limit (LOD) of 6 nM. Thus, the reported sensor has a high selectivity, satisfactory accuracy and precision, and it may provide the potential application in the biological and environmental fields.
研究领域:
材料科学
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分析化学
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环境科学
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DOI
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 21
·17323-17330
·
IF 3.201
Xiangning Bu,Yongxin Fu,Hui Jin,Rijun Gui
This work demonstrates a novel, facile and efficient biosensor for dual-emission ratiometric and visual fluorescence detection of choline. Copper nanoclusters (CuNCs) were prepared by using N2H4·H2O as the reducing agent and lysozyme as the stabilizer, based on an ambient hydrothermal method. The prepared CuNCs were blue-emitting and showed an emission peak centered at 440 nm. In the mixture system consisting of CuNCs, choline oxidase, horseradish peroxidase (HRP) and o-phenylenediamine (OPD), the added choline was catalyzed by choline oxidase to generate H2O2. OPD was oxidized by H2O2 and HRP to generate 2,3-diaminophenazine (DAP). As the oxidation product of OPD, DAP emitted a fluorescence peaked at 550 nm and the fluorescence exhibited a regular enhancement with the increase of the choline concentration. Meanwhile, the fluorescence of the CuNCs was reduced by DAP due to an internal filtration effect-induced fluorescence quenching. There is an optimal linear relationship (r = 0.9992) between the ratiometric fluorescence intensity (IDAP/ICuNCs, I550/I440) and the choline concentration in the range of 0.1–80 μM, with a low limit of detection of 25 nM. The response of IDAP/ICuNCs to choline was sensitive and selective over potential interferents existing in real samples. This developed sensor enabled the naked-eye visual detection of choline in aqueous solutions and on immersed filter papers. In human serum and liquid milk samples, this sensor showed a superior performance for choline detection.
研究领域:
生物传感器
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分析化学
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生物医学工程
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DOI
高影响因子
ACS Omega
·
2021
·
IF 3.512
Ying Li,Ya-Qi Wang,Dan Liu,Yu Gao,Sai-Nan Wang,Hanxun Qiu
Herein, we develop a novel method to synthesize lanthanide-functionalized carbon quantum dots via free-radical copolymerization using the methyl methacrylate (MMA) monomer as a functional monomer and introducing a lanthanide complex to obtain the dual-emission fluorescent composite material FCQDs-Ln(TFA)3 (Ln = Eu, Tb; TFA: trifluoroacetylacetone). The obtained composites were fully characterized, and their structures were investigated by Fourier transform infrared spectroscopy (FTIR), 1H NMR spectroscopy, X-ray photoelectron spectroscopy (XPS), and transmission electron microscopy (TEM). Subsequently, a series of white-light-emitting polymer composite films FCQDs- (Eu:Tb)(TFA)3/poly(methyl methacrylate) (PMMA) were designed and synthesized by adjusting the ratio of Eu(TFA)3/Tb(TFA)3 under different wavelengths. More significantly, FCQDs-Tb(TFA)3 was selected as a sensitive probe for sensing metal cations due to excellent photoluminescence properties, revealing a unique capability of FCQDs-Tb(TFA)3 of detecting Fe(III) cations with high efficiency and selectivity. Furthermore, the sensing experiment results indicated that FCQDs-Tb(TFA)3 is ideal as a fluorescent nanoprobe for Fe3+ ion detection, and the lowest detection limit for Fe3+ is 0.158 μM, which is superior to many other previous related research studies. This pioneering work provides a new idea and method for constructing a dual-emission ratio sensor based on carbon quantum dots and also extends the potential application in the biological and environmental fields.
研究领域:
材料科学
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分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Chenyue Kang,Caihong Zhang,Yan Zhang,Guomei Zhang,Shaomin Shuang
Ciprofloxacin (CIP) plays an important role in many physiological processes. Previously reported methods for CIP detection have many drawbacks and so it is crucial to develop highly sensitive methods to detect CIP. In this study, a dual-emission ratiometric fluorescent probe (SF-CQDs/CuAg NCs) of a nanocomposite of carbon quantum dots (SF-CQDs) and copper-silver bimetallic nanoclusters (CuAg NCs) was developed for sensitive and selective detection of CIP. The fluorescent signal of CuAg NCs was quenched while the fluorescence intensity of SF-CQDs was enhanced in the presence of CIP. The working principle of the fluorescent probe SF-CQDs/CuAg NCs is mainly based on the complexation of CIP with CuAg NCs to free SF-CQDs. The quenching of CuAg NCs by CIP arises from the chelation between the metal and the 1-oxo substituent and the adjacent carboxyl group of CIP. The fluorescence recovery of SF-CQDs is attributing to the release of SF-CQDs from SF-CQDs/CuAg NCs and the hydrogen bonding interaction between SF-CQDs and CIP. The ratiometric fluorescence measurement of SF-CQDs/CuAg NCs has been employed to analyze CIP with good sensitivity and selectivity. The working range of CIP is 5.0–200.0 μM and the detection limit is 3.3 μM. More importantly, the fluorescence of SF-CQDs/CuAg NCs can be detected intuitively via a smartphone which can be applied to determine CIP.
研究领域:
分析化学
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生物医学工程
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Yueying Wang,Wenting Li,Xuetao Hu,Xinai Zhang,Xiaowei Huang,Zhihua Li,Miaoyun Li,Xiaobo Zou,Jiyong Shi
A ratiometric fluorescence sensor system is proposed for detecting bis(2-ethylhexyl) phthalate (DEHP) in pork, which is based on aptamer recognition with molybdenum disulfide quantum dots and cadmium telluride quantum dots (MoS 2 QDs/CdTe-Apta). Two signals exist in the system, among which the response signal is transmitted by CdTe-Apta. The amide condensation between aptamers and CdTe QDs shortens the distance between CdTe QDs and DEHP, thus quenching the fluorescence of CdTe QDs, possibly through a photoinduced electron transfer mechanism. The MoS 2 QDs deliver the self-calibration signal, and the fluorescence of MoS 2 QDs remains almost constant when co-existing with DEHP. Linearity (R 2 = 0.9536) was established for the DEHP concentration range 0.005–3.0 mg·L −1 , with a limit of detection of 0.21 μg·L −1 . The system was successfully applied in the determination of DEHP in pork. The system has potential for the quantitative determination of DEHP in practical applications.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Environmental Technology & Innovation
·
2025
·
IF 7.1
Yu He,Suqing Liu,Yan Zhou,Junping Wang
At present, with the development of society, different enterprises inevitably produce industrial wastewater and waste residue containing lead and copper. Therefore, there is an urgent need for a rapid and simple method to detect lead and copper in pollutants. In this paper, a metal-organic framework (MOF) doped with Eu(Ⅲ) (Eu 3+ /UiO-66-NH 2 ) was successfully prepared by one-pot hydrothermal technique. The probe is capable of detecting Pb 2+ and Cu 2+ with high sensitivity. Pb 2+ and Cu 2+ have detection ranges of 5–340 μM and 0.01–200 μM, respectively. The detection limit for Pb 2+ was as low as 1.01 μM, and the detection limit for Cu 2+ was 6.46 μM. This approach has a good detection performance when compared to the method described in the literature. It shows that the prepared sensor has great potential in the detection of actual lead and copper, and provides a practical and effective method for rapid and accurate detection of heavy metal ions.
研究领域:
环境监测
·
分析化学
·
材料科学
·
重金属检测
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 6
·788-796
·
IF 3.1
Yue Xin,Dun Zhang,Yan Zeng,Yingwen Wang,Peng Qi
Adenosine triphosphate (ATP) is the primary energy carrier for intracellular metabolic processes. Accurate and rapid detection of ATP has important implications for clinical diagnosis. In this work, we reported a dual-emission ratiometric fluorescent probe Cu NCs–Al@ZIF-90 formed by encapsulating copper nanoclusters (Cu NCs) into zeolitic imidazolate framework-90 (ZIF-90) using a simple one-pot method. Cu NCs exhibited a remarkable fluorescence enhancement in the presence of aluminum ions due to the aggregation-induced emission (AIE) properties. When ATP existed, the Zn2+ nodes in the MOF material acted as selective sites for ATP recognition, resulting in the cleavage of Cu NCs–Al@ZIF-90. As a consequence, two reverse fluorescence changes were observed from released Cu NCs at 620 nm and imidazole-2-carboxaldehyde (2-ICA) at 450 nm, respectively. With the dual-emission ratiometric strategy, efficient and rapid determination of ATP was realized, giving a detection limit down to 0.034 mM in the concentration range of 0.2 mM to 0.625 mM. The convenient synthesis process and the rapid ATP-responsive ability made the proposed Cu NCs–Al@ZIF-90 probe highly promising in clinical and environmental analysis.
研究领域:
分析化学
·
生物医学工程
·
材料科学
·
临床诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 28
·17283-17290
·
IF 3.361
Shuai Zhang,Cong Zhang,Xiaodong Shao,Rentian Guan,Yingying Hu,Keying Zhang,Wenjing Liu,Min Hong,Qiaoli Yue
A fluorometric method was proposed for the determination of Fe3+ and ascorbic acid (AA) based on blue and red dual fluorescence emissions of glutathione (GSH) stabilized-gold nanoclusters (AuNCs). AuNCs were synthesized from GSH and tetrachloroauric acid. The fluorescence peaks of AuNCs were at 425 nm and 585 nm, respectively. In the presence of Fe3+, the fluorescence peak at 425 nm can be enhanced and that at 585 nm can be quenched. There is a good linear relationship between the fluorescence intensity ratio for the 425 and 585 nm peaks (F425/F585) and the concentration of Fe3+ in the range of 0.75–125 μM. However, when AA was added to the AuNCs–Fe3+ system, the value of F425/F585 decreased consistently with the concentration of AA in the range of 0.25–35 μM. The limit of detection for Fe3+ and AA was 227 and 75.8 nM, respectively. The interaction between AuNCs and Fe3+ can induce the ligand–metal charge transfer (LMCT) effect leading to the fluorescence increment at 425 nm, while AA can reduce Fe3+ to Fe2+. The production of Fe2+ can not enhance or quench the fluorescence of AuNCs. By comparison with previous literature, the AuNCs prepared here show two fluorescence peaks without additional fluorescence labels. Furthermore, the method was successfully applied in the determination of Fe3+ and AA in some real samples, such as water, human serum and tablets.
研究领域:
分析化学
·
纳米技术
·
环境科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）