Journal of Materials Chemistry B
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2019
·Vol. 8
·期 3
·426-437
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IF 5.047
Xueru Shan,Qian Chen,Xiangyu Yin,Chunzhu Jiang,Tinghua Li,Shanshan Wei,Xinyu Zhang,Guoying Sun,Jianhua Liu,Lehui Lu
Nanotheranostic agents that can simultaneously provide real-time tracking and accurate treatment at tumor sites are playing an increasingly important role in medicine. Herein, a novel polypyrrole (PPy)-based theranostic agent containing double rare-earth elements (PPy@BSA-Gd/Dy NPs) was successfully synthesized via an integrated strategy combining biomineralization and oxidation polymerization. The obtained PPy@BSA-Gd/Dy NPs with a diameter of approximately 59.48 ± 6.12 nm exhibited excellent solubility, long-term stability, superior biocompatibility, and negligible toxicity. Importantly, due to its intrinsic paramagnetic and strong X-ray attenuation ability, this agent demonstrated brilliant imaging performance in both T1/T2-weighted magnetic resonance imaging (MRI) and X-ray computed tomography (CT) imaging in vitro and vivo. Additionally, with an excellent photothermal conversion efficiency (26.61%) upon irradiation by an 808 nm laser, this theranostic agent showed significant photothermal cytotoxicity against HeLa cells and 4T1 cells in vitro and antitumor efficacy through intravenous injection in vivo. Meanwhile, biodistribution and blood circulation were also used to explore its fate in vivo. In summary, this study highlighted the versatility and practicability of PPy@BSA-Gd/Dy NPs and also suggested that the agent may be a promising candidate for T1/T2-weighted MRI/CT tri-modal imaging guided photothermal cancer therapy.
研究领域:
医学
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材料科学
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生物医学工程
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DOI
PubMed
高影响因子
OPTICAL MATERIALS
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2022
·
IF 3.754
Xiaozhan Yang,Yicun Liang,Jing Shi,Yuanqiang wang,Wenlin Feng
Dual-lanthanide hollow metal-organic frameworks, Tb 1 -x / Eu x -MOFs ( x = 0, 0.02, 0.04, 0.06, 1) were successfully synthesized by a one-pot solvothermal method. The tunable luminescence color of green-yellow-orange-red can be achieved by variation of the Tb 3+ /Eu 3+ ratio. The energy transfer between Tb 3+ and Eu 3+ is confirmed by monitoring the excited states lifetime of 5 D 4 (Tb 3+ ) and 5 D 0 (Eu 3+ ), and can be regulated by water content , which indicates that organic ligand, 1,3,5-benzenetricarboxylic acid (H 3 BTC) has good antenna effect. Also, Tb 0.98 / Eu 0.02 -MOFs are used to be luminescence sensors for the detection of trace water and nitrobenzene (NB). By simultaneous monitoring of the emission intensity at 545 nm and 617 nm, the detection limits (LODs) for water are 0.0068% and 0.0081%, respectively. Those for NB are 0.0962 ppm and 0.0668 ppm, respectively. The sensing mechanisms (energy transfer for water and electron transfer for NB) are determined.
研究领域:
材料科学
·
分析化学
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Wei Jiang,Run-Han Yan,Ru-Ping Liang,Jian-Ding Qiu
Developing high-efficiency sorbents for the removal of fluoroquinolone (FQ) contaminants is of great significance for water environmental conservation. In this study, double lanthanide ions were loaded onto a specially designed SO 3 H-decorated covalent organic framework (TpPa-SO 3 H) to obtain hybrid sorbent material (Tb-Eu@TpPa-SO 3 H) for the removal of typical FQs present in wastewater. Tb-Eu@TpPa-SO 3 H was a porous nanostructure of high density with evenly distributed Tb, Eu and sulfonic acid as active groups. Sulfonic acid groups could bind amine sites of FQs molecules through electrostatic interaction. Double lanthanide ions binded FQs according to dinuclear charge transfer complex with β-diketones unit in FQs molecule. Tb-Eu@TpPa-SO 3 H with multiple active sites exhibited a synergistic effect for FQs adsorption from water. Tb-Eu@TpPa-SO 3 H revealed unprecedentedly high adsorption capacity of 1111, 1147, and 1176 mg/g for norfloxacin (NOR), ciprofloxacin (CIP), enrofloxacin (ENR), respectively, accompanied by fast removal rates (99 % adsorption efficiency within 2 min). Further, the results of analysis on contaminated seawater suggested enormous potential of the developed material Tb-Eu@TpPa-SO 3 H in practical applications. These findings promoted the development of the designs and preparations of lanthanide functionalized covalent organic framework hybrid materials and their application to the removal of organic contaminants.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF FLUORESCENCE
·
2025
·
IF 3.1
Yan Zitao,Zhu Dachuan
A series of dual-lanthanide metal–organic frameworks (MOFs: Dy 1-x Ce x -BTC) have been successfully prepared by hydrothermal method using dysprosium (Dy 3+ ) and cerium (Ce 3+ ) ions as metal sources and 1,3,5-benzenetricarboxylic acid (H 3 BTC) as organic ligand, confirmed by XRD patterns and FT-IR spectra, and then the luminescence property, the application in detecting small organic molecules and structural stability have been discussed. Among the samples, Dy 0.8 Ce 0.2 -BTC exhibited two strongest emission peaks located at 485 nm and 578 nm under the excitation at 295 nm, which are attributed to the excited electronic transitions of Dy 3+ from 4 F 9/2 to 6 H 15/2 and 6 H 13/2 . However, Dy 0.8 Ce 0.2 -BTC immersed in the solution of acetaldehyde (AH) demonstrated an obvious luminescence quenching with the calculated quenching constant ( K sv ) and the limit of detection ( LOD ) as 7.08 × 10 3 M −1 , 5.36 × 10 –7 M and high selectivity among the other tested organic solvents. Meanwhile, it revealed that the MOF could maintain good microstructural and recycle stability in deionized water, indicating a great potential as a turn-off fluorescent sensor for AH detection. Besides, the luminescence quenching mechanism was deduced from competitive absorption.
研究领域:
材料科学
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化学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Xiaofang Liu,Wenxia Tian,Huan Liu,Yi Ma,Danqun Huo,Changjun Hou
Discrimination of segmented Baijiu contributes to stabilizing the quality of products, improving revenue-generating effects. A fluorescence sensor array is constructed based on four fluorescence characteristic peaks of terbium@lanthanum metal–organic framework (Tb@La-MOF). Its fluorescence signal is specifically quenched, when Tb@La-MOF encounters acetaldehyde. Acetaldehyde may inhibit the absorption of energy by the organic ligands in MOF, or/and hydrogen bonding with –COOH on the organic ligand, resulting in energy transfer to Tb(Ⅲ). According to this, the quantitative detection of acetaldehyde is completed with a range of 10–300 μM and the detection limit of 5.5 μM. At the same time, it has been successfully applied to the discrimination of segmented Baijiu. Fifteen segmented from three wine cellars are 100 % discriminated with the combined processing of sensor arrays and analytical methods. Accuracy, simplicity, and low-cost are highlights of this fluorescence sensor array, which has considerable potential for application in detection, production, and food field.
研究领域:
分析化学
·
食品科学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）