INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 17
·10201
·
IF 6.208
Xiamei Kang,Xiao Zhou,Yanting Tang,Zhijie Jiang,Jiaqi Chen,Muhammad Mohsin,Min Yue
Salmonella enterica,serovar Gallinarum, biovar Pullorum, is an avian-specific pathogen which has caused considerable economic losses to the poultry industry worldwide. Two-component systems (TCSs) play an essential role in obtaining nutrients, detecting the presence of neighboring bacteria and regulating the expression of virulence factors. The genome analysis ofS. Pullorum strain S06004 suggesting the carriage of 22 pairs of TCSs, which belong to five families named CitB, OmpR, NarL, Chemotaxis and LuxR. In the CitB family, three pairs of TCSs, namely CitA-CitB, DcuS-DcuR and DpiB-DpiA, remain unaddressed inS. Pullorum. To systematically investigate the function of the CitB family inS. Pullorum, four mutants, ΔcitAB(abbreviated as Δcit), ΔdcuSR(Δdcu), ΔdpiBA(Δdpi) and ΔcitABΔdcuSRΔdpiBA(Δ3), were made using the CRISPR/Cas9 system. The results demonstrated that the CitB family did not affect the growth of bacteria, the results of biochemical tests, invasion and proliferation in chicken macrophage HD-11 cells and the expression of fimbrial protein. But the mutants showed thicker biofilm formation, higher resistance to antimicrobial agents, enhanced tolerance to inhibition by egg albumen and increased virulence in chicken embryos. Moreover, the deletion of Dpi TCS was detrimental to survival after exposure to hyperosmotic and oxidative environments, as well as the long-term colonization of the small intestine of chickens. Collectively, we provided new knowledge regarding the possible role of the CitB family involved in the pathogenic processes ofS. Pullorum.Keywords:SalmonellaPullorum;CitB family;Two-component system;Pathogenesis
研究领域:
微生物学
·
分子生物学
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产品关联
DOI
PubMed
高影响因子
SURFACE AND INTERFACE ANALYSIS
·
2021
·Vol. 53
·期 12
·1059-1068
·
IF 1.607
Ying Wang,Minhao Yin,Aiguo Tang,Xianjuan Pang,Ningyi Yuan,Jianning Ding
In this paper, the dual-component silane films composed of trimethoxysilane and bis[3-(triethoxysilyl)propyl]tetrasulfide (BTESPT) were prepared on the surface of AZ31B Mg alloys. The selected trimethoxysilanes had different chain length. The results showed that the dual-component silane films could effectively enhance the corrosion resistance of Mg alloys. Moreover, with the enlarging of the chain length of trimethoxysilane, the hydrophobic property and the corrosion resistance of the dual-component silane films were enhanced. And the dual-component silane film composed of BTESPT and octadecyltrimethoxysilane (OTMS) showed the highest contact angle and the best corrosion resistance. It could be ascribed to the high density of CH 2 groups and –S–S–S–S– in the dual-component silane film, greatly improving the hydrophobicity and the anticorrosion property. Simultaneously, the substantial Si–O–Si network in the dual-component silane film also enlarged the length of the penetration paths for corrosive media, delaying the corrosion of the Mg alloy.
研究领域:
材料科学
·
腐蚀与防护
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DOI
高影响因子
DRUG DELIVERY
·
2020
·
IF 4.902
Chunyun Wang,Peilan Qi,Yan Lu,Lei Liu,Yanan Zhang,Qianli Sheng,Tianshun Wang,Mengying Zhang,Rui Wang,Shiyong Song
The Editors and Publisher of the journal Drug Delivery, have retracted the following article:Chunyun Wang, Peilan Qi, Yan Lu, Lei Liu, Yanan Zhang, Qianli Sheng, Tianshun Wang, Mengying Zhang, Rui Wang & Shiyong Song (2020) Bicomponent polymeric micelles for pH-controlled delivery of doxorubicin, Drug Delivery, 27:1, 344–357, DOI: 10.1080/10717544.2020.1726526Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been unable to fully address the concerns raised. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. All authors listed in this publication have been informed.We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.
研究领域:
药学
·
生物材料
·
肿瘤治疗
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DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Jingge Ju,Zongjie Li,Yi Lv,Mengyao Liu,Kaouthar Fejjari,Weimin Kang,Yuan Liao
Membrane distillation (MD) is an attractive membrane process for seawater and brine water desalination. One of the main obstacles for MD application is the absence of an effective MD membrane with high water permeability and an excellent salt rejection. This work proposes a novel design strategy of hydrophobic/hydrophilic bi-component membranes for MD by electrospinning and calcination . Unlike the conventional dual-layer hydrophobic/hydrophilic membranes, the bi-component membrane developed in this work is composed of multiple layers of hydrophilic polyimide (PI) nanofibers and hydrophobic polytetrafluoroethylene (PTFE) microclusters, which interweave with each other in the entire membrane. The optimal hydrophobic/hydrophilic bi-component membrane #PTFE/PI-2 shows robust three-dimensional (3D) superhydrophobic and self-cleaning properties. It exhibits a highly competitive permeation flux of 42 ± 3 L m −2 h −1 and an excellent salt rejection above 99.9% in a 400-h continuous DCMD operation when the feed solution was synthetic seawater with a NaCl concentration of 3.5 wt% at 60 °C. Moreover, it is able to achieve an outstanding water flux of 40 ± 2 L m −2 h −1 and a salt rejection over 99.9% when the feed solution was brine water with a NaCl concentration of 25 wt%. The high vapor permeability of #PTFE/PI-2 should be attributed to the high membrane porosity, negligible mass transfer resistance of PI nanofibers and more effective water evaporation area on its superhydrophobic surface. Meanwhile, the excellent anti-wetting property should be due to a unique 3D superhydrophobicity constructed by multiple layers of PTFE microclusters.
研究领域:
材料科学
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环境工程
·
化学工程
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产品关联
DOI
高影响因子
Polymers
·
2022
·Vol. 14
·期 12
·2504
·
IF 4.967
Zijian Dai,Jianyong Yu,Yang Si
Recently, MnO2-coated polymeric filters have shown promising performance in room-temperature formaldehyde abatement. However, a commonly known concern of MnO2/polymer composites is either MnO2crystal encapsulation or weak adhesion. This work reports a low-cost high-throughput and green strategy to produce binder-free MnO2-nonwoven composite air filters. The production approach is energy saving and environmentally friendly, which combines MnO2crystal coating on bicomponent polyolefin spunbond nonwovens and subsequent heat immobilizing of crystals, followed by the removal of weakly bonded MnO2. The binder-free MnO2-nonwoven composites show firm catalyst-fiber adhesion, a gradient porous structure, and excellent formaldehyde removal capability (94.5% ± 0.4%) at room temperature, and the reaction rate constant is 0.040 min−1. In contrast to the MnO2-nonwoven composites containing organic binders, the HCHO removal of binder-free filters increased by over 4%. This study proposes an alternative solution in producing catalyst/fabric composite filters for formaldehyde removal.Keywords:MnO2;bicomponent polyolefin nonwovens;polymeric filter;binder-free;HCHO removal
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small Methods
·
2024
·
IF 10.7
Lu Hou,Wen-Cui Li,Sijia Wang,An-Hui Lu
Ringy nanostructures are amazing materials, displaying unique optical, magnetic, and electronic properties highly related to their dimensions. A strategy capable of continuously tailoring the diameter of nanorings is the key to elucidating their structure-function relationship. Herein, a method of bi-component micellar-configuration-transformation induced by hydrophobicity for the synthesis of nanorings with diameters ranging from submicron (≈143 nm) to micron (≈4.8 µm) and their carbonaceous analogs is established. Remarkably, the nanorings fabricated with this liquid phase strategy achieve the record for the largest diameter span. Through varying the molecular lengths of fatty alcohols and copolymers, shortening the molecular length of fatty alcohol can swell the primary micelles, improve the exposure of hydrophobic component and boost the assembly kinetics for ultra-large nanorings is shown here. On the other hand, shortening the molecular length of the copolymer will give rise to ultra-small nanorings by reducing the size of primary micelles and shortening the assembly time. When assembling the nanorings into monolayer arrays and then depositing Au, such substrate displays enhanced surface-enhanced Raman scattering (SERS) performance. This research develops a facile method for the controllable synthesis of ringy materials with multiscale tunable diameters and may inspire more interesting applications in physics, optical, and sensors.
研究领域:
材料科学
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化学
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2014
·
IF 4.086
Fang Sun,Guoxin Zhang,Yuqi Xu,Zheng Chang,Pengbo Wan,Yaping Li,Xiaoming Sun
CoO x incorporated in Ag/reduced graphene oxide nanocomposites (CoO x -Ag/rGO) were synthesized through an one-pot solvothermal method. Electrochemical results showed that CoO x nanoparticles could greatly promote dispersion of anchored Ag nanoparticles and increase the limiting current density for the whole CoO x -Ag/rGO nanocomposites when catalyzing oxygen reduction reaction (ORR) in alkaline medium. With CoO x formation beside the Ag nanoparticles, a much higher current density and a preferable four-electron pathway were achieved for the CoO x -Ag/rGO nanocomposites. Meanwhile, the CoO x -Ag/rGO nanocomposites showed remarkable long-term stability and tolerance toward methanol than the commercially available 20% Pt/C catalyst. More importantly, this work could finally lead to a practical significance for developing high-performance bicomponent electrocatalysts with low-cost for fuel cells and relevant electrochemical technologies.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Hui Xiong,Xinyi Hu,Xiaoying Qi,Zhao Jiang
It is essential to design and produce stable, high-activity, and low-cost anode catalysts for direct methanol fuel cells (DMFCs). To improve the efficiency of the methanol oxidation reaction (MOR) in alkaline media, a series of PdM-NbN/C (M=Co, Ni, Cu) bi-component catalysts were synthesized by introducing various oxyphilic metals. Electrochemical evaluations show that the presence of Ni and Co significantly enhances catalytic activity, charge transfer kinetics, CO tolerance, and long-term stability compared to Pd-NbN/C. Among these, PdNi-NbN/C exhibits the highest mass activity of 4806.67 A·g Pd −1 , the lowest onset potential and charge transfer resistance, as determined from electrochemical testing. The rate-determining step (RDS) is identified as the CO ads oxidation reaction. Characterization analysis confirms that the second oxyphilic metals primarily optimize the Pd electronic structure and modulate the interaction between Pd and NbN, making a favorable shift in the d-band centers. Additionally, Ni and Co elements tend to form hydroxides in higher proportions, which aids in the removal of CO ads and accelerates the RDS. The electronic interactions between Pd, Ni, and NbN species are key to the enhanced catalytic performance for MOR. Pd nanoparticles in the electron-deficient condition may aid in the activation of methanol and its intermediates, as indicated by the linear relationship between the mass activities and d-band centers. This work offers important information for the logical design of efficient anode catalysts for DMFCs.
研究领域:
材料科学
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电化学
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燃料电池
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产品关联
DOI
高影响因子
Biomedical Materials
·
2025
·Vol. 20
·期 3
·035020
·
IF 3.7
Jinju Ding,Xuehua Zhao,Chengkai Xuan,Jiayi Lin,Cuiping Zhang,Xuetao Shi
Compared with traditional soft tissue wound closure methods such as sutures and staplers, bioadhesives have significant advantages in terms of tissue compatibility, ease of use, and wound adaptability, making them a hot topic among current wound repair materials. This study aimed to select polyurethane materials with good biocompatibility and high mechanical strength, optimize the prepolymer formula, develop new curing agents, and obtain a new dual-component polyurethane bioadhesive. Furthermore, key research will be conducted on its mechanical properties and tissue adhesion performance. The results show that through the optimization of prepolymer formulations and the development of novel curing agents, a dual-component polyurethane bioadhesive with good biocompatibility, flexibility, and high adhesive strength was obtained. This adhesive can quickly and effectively bond common soft tissue (skin, muscle) traumatic wounds, with an adhesive strength of up to 72 kPa. This adhesive matches well with the mechanical properties of soft tissues and safely and tightly adheres to the surface of soft tissues. Additionally, this dual-component polyurethane adhesive holds promise for repairing other soft tissues, such as the lungs and intestines, with broad application prospects.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·Vol. 141
·期 23
·e55477
·
IF 2.7
Zhenhua Lu,Chuncheng Pan,Yong Hou,Zhaobin Zhang,Jiakuan Fu,Peng Li
Polyether polyols can improve the performance of waterborne epoxy curing agent. In this paper, intermediates were synthesized from polyether triols with epoxy resin E-51 and introduced into the epoxy curing agent by reacting with TETA. This paper focuses on the process of synthesizing the intermediates. The 2K waterborne epoxy coating film prepared with polyether triols-modified waterborne epoxy curing agent exhibits desirable corrosion protection capacity and neutral salt spray resistance up to 600 h. In addition, the 2K waterborne epoxy coating film prepared using the modified waterborne epoxy curing agent with polyether triols displayed improved surface appearance, mechanical properties, and water resistance.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Polymer Materials
·
2024
·
IF 4.4
Yubing Han,Ying Zhang,Peng Huang,Bori Shi,En Xie,Chang Xue,Weijia Wen,Huayan Pu,Mengying Zhang,Jinbo Wu
Dielectric elastomer actuators (DEAs) with reversible large electrically actuated strains can be used to build lightweight and flexible crawling robots. Silicone rubber (SR) has become a research hotspot for dielectric elastomer (DE) materials due to its stable performance and fast response speed (ms), but it has the problems of a small actuation strain, a low dielectric constant, and a large driving electric field, which seriously limit the actuation performance of DEAs. To solve this problem, in this paper, carbon dots (CDs) were grafted onto BaTiO(C2O4)2@urea (BTRU) core–shell nanoparticles to successfully synthesize BaTiO(C2O4)2@urea/CDs (BTRU/CDs) nanoparticles with a bicomponent shell structure. These bicomponent shell structure nanoparticles were added as a filler phase to plasticized SR to obtain BTRU/CDs/SR composite films with enhanced mechanical and dielectric properties. For the 15 wt % BTRU/CDs/SR elastomer simultaneously exhibiting an ideal modulus (∼0.193 MPa), a high toughness (elongation ∼849.5%), and satisfactory dielectric properties (εr = 6.91@1 Hz), accordingly, the out-of-plane actuation displacement can reach 3.28 mm (10 kV/mm@1 Hz), which is 683% higher than the pure matrix. Compared with VHB 4910, the area strain rate (42.4%@22 kV/mm) and average crawling speed (10 mm/s, 3 kV@8 Hz) of DEA and a flexible crawling robot prepared based on our elastomer are 4.4 times and 1.3 times higher, respectively. These valuable findings may provide a strategy for preparing high-performance DEs for applications in the field of flexible actuators or flexible robots.
研究领域:
材料科学
·
机器人学
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 14
·11739-11745
·
IF 3.201
Ying-Tao Zhao,Xu Yan,Hong-Wei He,Meng-Nan Liu,Xiao-Xiong Wang,Guang-Di Nie,Jun Zhang,Jie Fu,Yun-Ze Long
Solvent recovery is a big challenge in conventional solution electrospinning for the large-scale production of ultrafine fibers because the precursor utilization ratio is usually less than 20 wt%. In this paper, we report an eco-friendly two-component electrospinning technique for the fabrication of acrylate composite fibers using a homemade device at room temperature. During this electrospinning process, the two-component spinning solutions (component A: t-butyl peroxy-2-ethyl hexanoate (BPOEH), isobornyl methacrylate (IBOMA), nitrile rubber (NBR), methacrylic acid (MAA); component B: N,N-dimethylaniline (DMA), IBOMA, NBR and MAA) are nearly all electrospun into ultrafine fibers, and the utilization ratio of the precursor can reach more than 90 wt%. The fiber solidification mechanism can be ascribed to the rapid polymerization of the IBOMA monomer in the presence of free radicals formed by a redox initiation system (BPOEH + DMA), which is different from the solvent evaporation in solution electrospinning or cooling solidification in melt electrospinning. Such a two-component electrospinning technique may stimulate the development of an eco-friendly approach to fabricate composite and functional ultrafine fibers.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）