Nanomaterials
·
2022
·Vol. 12
·期 11
·1909
·
IF 5.719
Chu-Ya Wang,Qi Zeng,Li-Xia Wang,Xin Fang,Guangcan Zhu
Based on the low utilization rate of visible light and the high-charge carriers-recombination efficiency of bismuth oxybromide (BiOBr), in this work, noble metal Ag was used to modify BiOBr, and Ag-doped BiOBr nanoplates (Ag-BiOBr) were obtained through a one-step hydrothermal method. Compared with BiOBr, the absorption edge of Ag-BiOBr showed a redshift from 453 nm to 510 nm, and the absorption efficiency of visible light was, obviously, improved. Bisphenol A (BPA) was chosen as the target pollutant, to evaluate the photocatalytic performance of the samples. Ag0.1-BiOBr showed the highest degradation efficiency. The intrinsic photocatalytic activity of Ag0.1-BiOBr, under visible light, was approximately twice as high as that of BiOBr. In this way, a new visible-light-driven photocatalyst was proposed, to fight against organic pollution, which provides a promising strategy for water and wastewater treatment.Keywords:bismuth oxybromide (BiOBr);Ag-doping modification;visible light;charge separation;bisphenol A (BPA)
研究领域:
环境科学
·
材料科学
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DOI
PubMed
高影响因子
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
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2021
·
IF 3.228
Qin Wang,Qing Chang,Mei Sun,Chenghao Liu,Jiahui Fan,Yijun Xie,Xiaoyong Deng
The complex combined effects of nanoparticles and environmental pollutants in the aqueous environment will inevitably affect aquatic ecosystem and human life. Bisphenol A (BPA) is listed as a typical kind of endocrine disruptors , there is little research about the joint toxicity of co-exposure of SiO 2 nanoparticles (NPs) and BPA. In this study, fluorescent ultra-small SiO 2 NPs (US-FMSNs) around 6.3 nm were synthesized and investigated for their combined effects with BPA on zebrafish during the early developmental stages within 4–168 h post fertilization (hpf). The results showed that US-FMSNs could accumulate in the chorion , abdomen and intestine in zebrafish. In addition, the different concentration (0.1, 1, 10 μg/mL) of BPA and US-FMSNs (200 μg/mL) demonstrated strong impact on multiple toxic endpoints at four periods (72, 96, 120, 168 hpf). We found US-FMSNs had no significant toxic effect on zebrafish, while BPA (10 μg/mL) showed a degree of developmental toxicity . Compared with single BPA (10 μg/mL) exposure, combined exposure enhanced the developmental toxicity of zebrafish, including increased mortality, decreased hatching rate and body length, and decreased activity of total superoxide dismutase (T-SOD) and increased malondialdehyde (MDA) levels. Our results indicated that US-FMSNs and BPA induced oxidative stress , and the effect of the co-exposure was less than that of single exposure (10 μg/mL). This study hereby provides a basis for the potential ecological and health risks of SiO 2 NPs and BPA exposure.
研究领域:
环境科学
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毒理学
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水生生态学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Zhongyi Fang,Jie Zhao,Yuan Li,Yu Wang,Tian Qiu,Yanlin Wu,Wenbo Dong,Gilles Mailhot
Fenton-like system had long been modified to promote its adaptability and efficiency by adding extra components like metal chelators or reducers. Nonetheless, chelator such as ethylene diamine tetraacetic acid (EDTA) was harmful in high dosage. While strong reducers could efficiently promote the generation speed of hydroxyl radicals (HO ), they could also get oxidized easily during storage time, for which further application was costly. In this study, (+)-catechin (CAT), an environmental- friendly component, was proved to be an efficient promoter of Fenton-like system on Bisphenol A (BPA) degradation. The modified system achieved 92% of BPA removal in one hour. The mechanism was studied, and the reaction procedure between CAT and Fe(III) together with the degradation pathways of CAT were identified. Fe(III) got chelated first by CAT and quickly reduced to Fe(II) via a single inner-compound electron transfer. The intermediates of CAT could further reduce one and a half more potion of Fe(III) on average. Consequently, massive amount of Fe(II) turned Fenton-like procedure to Fenton reaction and thus promoted the generation of HO . The main radicals contributed on BPA degradation was HO . BPA could be efficiently degraded at pH 6.5 or acidic pH range, but the degradation was completely inhibited with the pH higher than 8.0. The optimal mole ratio between Fe(III) and CAT was 6:1 and the degradation pathway of BPA was deduced.
研究领域:
环境化学
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水处理
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污染物降解
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绿色化学
✓ 已验证
产品关联
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Mei Du,Jingzhang Liu,Bang Huang,Qiong Wang,Fengbang Wang,Lei Bi,Chunyan Ma,Maoyong Song,Guibin Jiang
Bisphenol A (BPA) and its analogs are endocrine-disrupting chemicals that are frequently detected in environmental and human samples. However, the effective removal of BPA and its analogs has not yet been extensively studied. Herein, we introduce a novel enzyme reactor for the degradation of BPA and its analogs in water. The influence of pore size on the degradation efficiency of immobilized laccase in the spatial nanopores of hydrogel was investigated using BPA as a representative compound. This showed that nanopores enhance the activity of immobilized laccases in a pore size-dependent manner and increase their stability. Compared with the same amount of free laccase, the 50 mg/L BPA degradation performance of laccase immobilized in 76 nm nanopores increased to 300 %. Taking advantage of magnetic separation, this immobilized laccase can be reused, and its degradation capacity was maintained at over 73.7 % after ten reactions. Moreover, the degradation of seven BPA analogs was 1.03–5.88 times higher using laccase immobilized in nanopores compared with free laccase. Also, the biocatalyst could efficiently degrade BPA analogs in real water matrix. This study opens up a new avenue for the removal of BPA and its analogs by immobilizing laccase in nanopores, overcoming the key limitations introduced by the short enzyme life span and non-reusability.
研究领域:
环境科学
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生物技术
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酶学
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水处理工程
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产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
Jingyuan Yue,Xiaojin Hu,Huijun Xie,Zhen Hu,Haiming Wu,Jian Zhang,Bo Sun,Lushan Wang
Bisphenol A (BPA) in seawater tends to be deposited in coastal sediments. However, its degradation under tidal oscillations has not been explored comprehensively. Hydroxyl radicals (·OH) can be generated through Fe cycling under redox oscillations, which have a strong oxidizing capacity. This study focused on the contribution of Fe-mediated production of ·OH in BPA degradation under darkness. The removal of BPA was investigated by reoxygenating six natural coastal sediments, and three redox cycles were applied to prove the sustainability of the process. The importance of low reactivity Fe(II) in the production of ·OH was investigated, specifically, Fe(II) with carbonate and Fe(II) within goethite, hematite and magnetite. The degradation efficiency of BPA during reoxygenation of sediments was 76.78–94.82%, and the contribution of ·OH ranged from 36.74% to 74.51%. The path coefficient of ·OH on BPA degradation reached 0.6985 and the indirect effect of low reactivity Fe(II) on BPA degradation by mediating ·OH production reached 0.5240 obtained via partial least squares path modeling (PLS-PM). This study emphasizes the importance of low reactivity Fe(II) in ·OH production and provides a new perspective for the role of tidal-induced ·OH on the fate of refractory organic pollutants under darkness.
研究领域:
环境科学
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化学
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海洋科学
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2021
·
IF 9.028
Chuanzi Gao,Haihong He,Wenhui Qiu,Yi Zheng,Yuyang Chen,Shiyao Hu,Xue Zhao
Bisphenol A (BPA) analogues, used in a range of products due to health concerns regarding BPA, have emerged as ubiquitous environmental contaminants worldwide. This study aims to evaluate the levels of nine bisphenols (BPs) and eight biomarkers (malondialdehyde, MDA; 8-hydroxy-2′-deoxyguanosine, 8-OHdG; estradiol, E2; follicle-stimulating hormone, FSH; luteinizing hormone, LH; complement compound 3, C3; immunoglobulin M, IgM and c-reaction protein, CRP) in human serum (n = 353) to explore their potential relationships. The detection rates (DRs) of eight BPs in serum samples taken from people working in a dense industrial area of Shenzhen (Guangdong Province, China) were over 72% except for bisphenol B (BPB) (DR = 27.5%). The mean concentrations of BPA, bisphenol P (BPP), BPB, bisphenol F (BPF), bisphenol FL (BPFL), 4,4′-dihydroxy-benzophenone (DHBP), bisphenol AF (BPAF), 4,4′-thiodiphenol (TDP) and bisphenol S (BPS) were 42.062, 2.083, 0.765, 0.578, 0.423, 0.402, 0.191, 0.120, and 0.071 ng/mL, respectively. BPA and BPFL were significantly correlated with the level of oxidative stress indices MDA and 8-OHdG; BPAF, BPB, and DHBP were strongly correlated with the level of endocrine disturbance indices E2, FSH, and LH; and BPF, DHBP, and BPAF were apparently related to the level of immune interference indices C3 and IgM. This study also suggests multiple impacts (oxidative stress, endocrine disturbance, and immune interference) mediated by BPs contaminants in vivo. To our knowledge, this is the first study to report the correlations among these nine serum BPs and oxidative stress and endocrine and immune system indices in human serum samples collected from dense industrial areas.
研究领域:
环境科学
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毒理学
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公共卫生
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内分泌学
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免疫学
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2017
·Vol. 8
·期 1
·1-13
·
IF 12.124
Zhang Zhaobin,Hu Ying,Guo Jilong,Yu Tong,Sun Libei,Xiao Xuan,Zhu Desheng,Nakanishi Tsuyoshi,Hiromori Youhei,Li Junyu,Fan Xiaolin,Wan Yi,Cheng Siyu,Li Jun,Guo Xuan,Hu Jianying
Bisphenol A (BPA) is used in the production of plastic but has oestrogenic activity. Therefore, BPA substitutes, such as fluorene-9-bisphenol (BHPF), have been introduced for the production of so-called ‘BPA-free’ plastics. Here we show that BHPF is released from commercial ‘BPA-free’ plastic bottles into drinking water and has anti-oestrogenic effects in mice. We demonstrate that BHPF has anti-oestrogenic activity in vitro and, in an uterotrophic assay in mice, induces low uterine weight, atrophic endometria and causes adverse pregnancy outcomes, even at doses lower than those of BPA for which no observed adverse effect have been reported. Female mice given water containing BHPF released from plastic bottles, have detectable levels of BHPF in serum, low uterine weights and show decreased expressions of oestrogen-responsive genes. We also detect BHPF in the plasma of 7/100 individuals, who regularly drink water from plastic bottles. Our data suggest that BPA substitutes should be tested for anti-oestrogenic activity and call for further study of the toxicological effects of BHPF on human health.
研究领域:
环境科学
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毒理学
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生殖生物学
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 14
·17290-17302
·
IF 3.056
Ma Lin,Yu Haiyang,Wang Xu,Li Dan,Zhang Yumin,Pei Xiucong,Duan Zhiwen,Ma Mingyue
The effect of prenatal bisphenol A (BPA) exposure is increasingly concerned. We investigated the effect of maternal BPA exposure during pregnancy on male offspring and its potential mechanism. Thirty pregnant Sprague Dawley (SD) rats were randomly divided into exposed and control groups. At PND56, the number of sperm, luteinizing hormone, and testosterone in the BPA-exposed group decreased, and testicular tissue structure was damaged in offsprings. At GD20, the miRNA profile in the testis of male offspring was examined and the expression levels of 28 deregulated miRNAs were validated by qRT-PCR. We found that miR-361-5p , miR-203a-3p , and miR-19b-2-5p had significantly different expression levels in the testis. These results suggest that maternal exposure to BPA can lead to differential changes in progeny miRNAs, which will provide direction for future in-depth mechanisms of reproductive injury.
研究领域:
生殖生物学
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毒理学
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分子生物学
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内分泌学
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产品关联
DOI
PubMed
高影响因子
ACS Catalysis
·
2021
·
IF 13.084
Lipeng Wu,Bin Li,Yang Li,Xiaobin Fan,Fengbao Zhang,Guoliang Zhang,Qing Xia,Wenchao Peng
Herein, a series of Co@N–C materials are synthesized using nitrates (LiNO3, NaNO3, and KNO3) as templates to control the preferential growth of the cobalt (200) facet. Co@N–C–X (X = LiNO3, NaNO3, and KNO3) exhibit excellent activities and long-term stabilities for Fenton-like degradation of bisphenol A (BPA) with peroxymonosulfate (PMS) as an oxidant. The texture coefficient (TC) is used to investigate the relationship between the Co facets and their catalytic activities, and a linear relation is built between the TC of Co(200) and the reaction rate constant (k). Co(200) is therefore the most active facet for PMS activation, while nitrates can promote the preferential growth of the Co(200) facet. Moreover, the Co(200) facet is more stable against leaching and can achieve more quick transformation between Co2+/Co3+. Quenching tests, electron paramagnetic resonance spectra, and electrochemical tests show that singlet oxygen (1O2) plays the dominant role for BPA degradation. Density functional theory verifies that Co nanoparticles coated with a graphitic nitrogen-doped carbon layer have the best activity for PMS activation. This work first proposes the strategy of using nitrates to control the preferential growth of Co facets and reveals the relationship between the TC value and k, thus attracting great interest in the environmental field.
研究领域:
环境科学
·
催化
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2025
·Vol. 14
·期 2
·214
·
IF 5.1
Mengge Duan,Yuting Wang,Shiyu Chen,Jiawen Lu,Ruihong Dong,Qiang Yu,Jianhua Xie,Yi Chen
Bisphenol A (BPA) and diisobutyl (DIBP) phthalate are widely used as typical plasticizers in food packaging. Plasticizers can be released from polymers, migrate into food, and be ingested by humans, leading to various health problems. However, little research has investigated the combined toxicity of BPA and DIBP, particularly their intestinal toxicity. Our goal is to analyse the combined toxicity of BPA (50 mg/kg) and DIBP (500 mg/kg) on the intestines of KM mice. Additionally, we tried to find natural products that can inhibit or prevent the combined toxicity of BPA and DIBP. The results indicated that the combination of BPA and DIBP exposure resulted in a reduction of beneficial flora, an increase in D-Lac levels (136 ± 14 μmol/L), an increase in intestinal permeability, activation of the notch pathway, and a decline in intestinal stem cells (ISCs) to goblet cells, compared to single-exposure sources. Nevertheless,Rubus chingiiHu phenolic extract (RHPE) (200, 400 and 600 mg/kg) ameliorated the BPA and DIBP-induced intestinal microbiota disruption and intestinal mucosal barrier impairment by inhibiting the overactivation of the notch pathway. The results of this study highlight the potential risks to human health posed by the combination of BPA and DIBP and may help explain the potential pathways of enterotoxicity caused by combined ingestion.
研究领域:
毒理学
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胃肠病学
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微生物学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Ning Chen,Jun Han,Xingchen He,Junhui Shao,Najun Li,Dongyun Chen,Jianmei Lu
Efficient and recyclable piezocatalysts are expected to use natural mechanical energy to degrade organic pollutants in water during piezoelectric degradation. Herein, flexible piezocatalytic membrane (HPVDF/Ti 3 C 2 ) was obtained by introducing Ti 3 C 2 nanosheets into PVDF with further hydrophilic modification. Polar functional groups on the Ti 3 C 2 surface interact with PVDF chains to form the high piezoelectric β-phase. The good conductivity of Ti 3 C 2 contributes to enhanced electron transport in PVDF/Ti 3 C 2 . The hydrophilic and porous HPVDF/Ti 3 C 2 composite membranes facilitate the abundant adsorption and catalytic sites. Thus, HPVDF/Ti 3 C 2 degraded BPA in water under ultrasonic vibration at a rate constant 29.5 times higher than that of the pure PVDF. Furthermore, HPVDF/Ti 3 C 2 membranes coated on stainless steel packing in filled column were found to be effective in the removal of bisphenol A (BPA) under conditions of peristaltic pump-driven water flow, thus providing a promising piezoelectric membrane for water purification using low-frequency mechanical energy from nature.
研究领域:
环境科学
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材料科学
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纳米技术
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水净化技术
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电化学
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高分子科学
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催化作用
✓ 已验证
产品关联
DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2021
·
IF 6.291
Ren Zhou,Ming Xia,Lei Zhang,Wei Cheng,Jia Yan,Yu Sun,Yan Wang,Hong Jiang
Exposure to many kinds of bisphenols (BPs) is common, and the effects of BP mixtures may differ from those of individual BPs. Therefore, evaluating combined exposure effects is necessary. Our study evaluated the individual and combined exposure effects of bisphenol A (BPA), bisphenol S (BPS) and bisphenol AF (BPAF) on embryonic development using an embryonic stem cell test (EST) and a concentration additive (CA) model at relatively high doses to uncover the interaction model of the three BPs. Environmentally relevant concentrations were then used to evaluate the possible effects of the individual and combined BPs at actual human exposure levels. Exposure to relatively high-dose BPA, BPS and BPAF inhibited embryonic stem cell differentiation into cardiomyocytes and exhibited weak embryo toxicity. Individually, BPA, BPS and BPAF inhibited endoderm, mesoderm and ectoderm marker expression but enhanced pluripotency marker expression. Combined exposure to BPs had an additive effect on cardiomyocyte differentiation and embryonic stem cell proliferation based on the CA model. Environmentally relevant individual or combined BP doses (10 ng/ml individual BPA, BPS and BPAF doses or 1 ng/ml and 10 ng/ml BP mixture doses) failed to cause oxidative stress, DNA damage or apoptosis changes in stem cell differentiation. The cardiomyocyte differentiation ratio also did not change significantly. Individual and combined exposure to environmentally relevant BP doses led to a significant increase in collagen expression. BPAF and the combination of BPs increased the type 1 collagen level, while the combination also increased the type 3 collagen level, which may be related to p38 pathway activation. The p38 pathway inhibitor SB203580 inhibited the increase in collagen during cardiomyocyte differentiation caused by low-dose BPs. These results suggest that relatively high-dose BPs in combination have an additive effect on cardiomyocyte differentiation. Low-dose BPs individually and in combination may affect cardiomyocyte collagen through the p38 pathway.
研究领域:
毒理学
·
发育生物学
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细胞生物学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）