International Journal of Precision Engineering and Manufacturing
·
2017
·Vol. 18
·期 5
·755-761
·
IF 1.497
Chen Zhichao,Zhang Xianglin,Chen Penghua,Li Wenchao,Zhou Kui,Shi Lei,Liu Kang,Liu Changqing
Recently, additive manufacturing is one of the most focused research topics due to its explosive development, especially in manufacturing engineering and medical science. In order to build 3D complex scaffolds with multi-biomaterials for clinical application, a new 3D multi-nozzle system with dual-mode drives, i.e. ejection and extrusion was developed. In this paper, much effort was made to gain fine control of droplet and excellent coordination during fabrication. Specifically, the parameters that influence the size and stability of droplet most was intensively studied. Considering that the biomaterials used in the future may have much difference in properties, the combination of parameters was investigated to facilitate the settings for certain-sized droplets, which are potentially eligible for bio-printing. The dispensing nozzles can work well both in independent and convergent mode, which can be freely switched. Outstanding to the most currently used 3D bio-printing techniques, this system can fabricate scaffolds with multimaterials of both low viscosity (by pneumatic dispensing) and high viscosity (through motor extrusion). It is highly expected that this system can satisfy clinical application in the near future.
研究领域:
制造工程学
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医学科学
·
生物打印技术
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DOI
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Zhiyue Cui,Hongli Fang,Xinyu Wei,Shu He,Wei Shao
Stimuli-responsive hydrogels have great prospects in many applications such as soft robots, smart actuators, and bionic devices. Among them, stimuli-responsive hydrogels as actuators possessing rapid responsiveness and tunable actuation remain challenging. In this work, asymmetric hydrogels with temperature and NIR light dual-responsive actuation were prepared by introducing polydopamine-modified molybdenum disulfide (PDA-MoS2) nanosheets into in situ polymerization of N-isopropylacrylamide (NIPAM) monomers by the gravity-induced deposition method. The PDA-MoS2 nanosheets existing in the PNIPAM hydrogels had synergistic reinforcing NIR light responsiveness, making the prepared hydrogel exhibit a fast bending ability that it could bend to 249° in 17 s. The hydrogel showed excellent bending performance with a bending angle of 601° in 16 s in 55 °C water. On this basis, several biomimetic actuators, including the catch-release of a smart gripper, the opening and closing of a hydrogel flower, and the bending of butterfly tentacles and light-driven circuit switches were developed. In addition, smart devices such as information-hiding materials and fluid valves were constructed through the combination of temperature and NIR light dual-responsiveness. These dual-driven asymmetric hydrogels provide ideas for the design and development of smart actuators and broaden the application of hydrogel actuators in the emerging fields of soft robotics, biomedical engineering, and bionic devices.
研究领域:
材料科学
·
生物医学工程
·
软体机器人技术
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产品关联
DOI
高影响因子
Micromachines
·
2024
·Vol. 15
·期 6
·685
·
IF 3
Xiaohui Yang,Yixian Li,Josh Zixi Lee,Yuanmin Sun,Xin Tan,Yijie Liu,Yang Yu,Huiqiang Li,Xue Li
Conventional microfluidic systems that rely on capillary force have a fixed structure and limited sensitivity, which cannot meet the demands of clinical applications. Herein, we propose a dual-drive microfluidic device for sensitive and flexible detection of multiple pathogenic microorganisms antigens/antibodies. The device comprises a portable microfluidic analyzer and a dual-drive microfluidic chip. Along with capillary force, a second active driving force is provided by a removable self-driving valve in the waste chamber. The interval between these two driving forces can be adjusted to control the reaction time in the microchannel, optimizing the formation of antigen-antibody complexes and enhancing sensitivity. Moreover, the material used in the self-driving valve can be changed to adjust the active force strength needed for different tests. The device offers quantitative analysis for respiratory syncytial virus antigen and SARS-CoV-2 antigen using a 35 μL sample, delivering results within 5 min. The detection limits of the system were 1.121 ng/mL and 0.447 ng/mL for respiratory syncytial virus recombinant fusion protein and SARS-CoV-2 recombinant nucleoprotein, respectively. Although the dual-drive microfluidic device has been used for immunoassay for respiratory syncytial virus and SARS-CoV-2 in this study, it can be easily adapted to other immunoassay applications by changing the critical reagents.
研究领域:
生物医学工程
·
病毒学
·
诊断学
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产品关联
DOI
PubMed
高影响因子
Materials Today Communications
·
2025
·
IF 4.5
Jiayu Xie,Ying Zhang,Huajun Wang,Gang Li,Wenfeng Qin,Chuanxi Lin,Ronghui Guo
Ice formation seriously affect helicopter flight performance, and serious ice accumulation will greatly threaten helicopter travel safety. To avoid the complex measures for surface ice protection and achieve integration, in this work, an ice defense membrane that based on polypyrrole (PPy) modified Ti 3 C 2 T x (MXene) and polydimethylsiloxane (PDMS) encapsulation was proposed. The test results show that membrane integrate the hydrophobicity (Contact angle could reach to 140.1°), dual-drive thermal property (Temperature of membrane could arrive at 116℃ and 68.3℃ at 7 V voltage supply and 100 mW/cm 2 near-infrared radiation, respectively), and micro-strain sensibility (0.05 % tiny strain for membrane could be sensed). Membrane with multifunction and high-integration can be effectively used in ice management. Anti-icing, deicing and ice detection tests were carried out to confirm the efficiency in passive anti-icing, active deicing, and ice formation detection. Moreover, an intelligent ice defense system based on the membrane and hardware circuit has been designed. This work puts forward a membrane with multifunctional integration for ice defense, which could powerfully deal with the icing problem for the aviation field in the future.
研究领域:
材料科学
·
航空航天工程
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产品关联
DOI
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Kai Xiang,Zhiying Xiao,Zheng Jing,Yuzhou Li,Meng Li,Zhikang Su,Ziyu Huang,Tianli Wu,Ping He,Yining Zhang,Fengyi Liu,Mingxing Ren,Sheng Yang
Cigarette smoke (CS) disrupts mitochondrial iron homeostasis, causing excess free iron to generate reactive oxygen species, leading to oxidative stress and impairing tissue repair. For smokers undergoing bone defect repair, achieving precise control over the balance between mitochondrial free iron and stored iron, while simultaneously enhancing endogenous iron homeostasis, poses a considerable challenge. This study introduces the iron balance dual-drive strategy (IBDS), which efficiently chelates mitochondrial free iron and promotes ferritin synthesis to create a FerritinBank for iron deposition, thus optimizing endogenous iron homeostasis. IBDS is delivered through an injectable, biodegradable iron-capturing hydrogel (SilMA/gelMA/DPT). The released DPT selectively targets and chelates free iron within mitochondria, modulating mitochondrial dynamics to restore their function. This action is complemented by the promotion of ferritin synthesis, which serves to bolster endogenous iron homeostasis and suppress ferroptosis. Transcriptomic sequencing and experimental data suggest that DPT corrects energy metabolism abnormalities and promotes mitochondrial macromolecule synthesis. In vivo studies confirm that the iron-capturing hydrogel significantly improves the healing of smoking-induced calvarial bone defects. This is the first report of nanoparticles promoting ferritin synthesis to build an endogenous iron reservoir, highlighting the potential of the IBDS strategy for bone regeneration in smokers and other iron-overload-related conditions.
研究领域:
医学
·
生物材料学
·
分子生物学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ming-hua Cheng,Xiang Xu,Hao-wen Zhang,Si-yu Kong,Zhe-sheng Feng,Fanbin Meng,Yan Wang
With the development of wearable devices, flexible multifunctional electromagnetic shielding (EMI) shielding materials have attracted widespread attention. In this paper, a fibrous ANF/PPy composite material was obtained by modifying aramid nanofibers (ANFs). Subsequently, the Ti 3 C 2 T x (MXene) suspension was mixed with the ANF/PPy solution, electrostatic self-assembly was performed, and an ANF/PPy/MXene composite film with a “brick (MXene)-mortar (ANF/PPy)” structure was prepared through vacuum-assisted filtration. The film has high electrical conductivity, certain mechanical tensile properties, high mechanical stability, good chemical stability, and excellent long-term stability. In addition, the film with a thickness of only 16 μm shows excellent EMI shielding (average EMI SE is 40.4 dB, absorption coefficient is 0.155, SSE/t is 36288.6 dB·cm 2 /g), dual‑driven (electrothermal and photothermal convertibility) heating and infrared thermal camouflage performance (radiation temperature is 69.4°C at a temperature of 150°C). These results show that ANF/PPy/MXene composite film is very promising in practical applications such as wearable devices, communications, high-performance heating, and infrared stealth.
研究领域:
材料科学
·
电子工程
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Biaobiao Yan,Shuaibing Huang,Yiwen Ren,Man Zhou,Yuanyuan Yu,Bo Xu,Li Cui,Qiang Wang,Ping Wang
MXene-based functional textiles have been widely studied and applied in many fields. However, the service stability of MXene combined with textile substrates in the environment is far from ideal, which makes its practical application a great challenge. Here we introduced gallic acid (GA), as natural reactive polyphenol compound to silk fibers through enzymatic polymerization, which significantly improved the durability of its conductivity. The small molecules of GA can covalently bind to the titanium atoms on the MXene nanosheets, and the tyrosine residues from silk fibroins can be enzymatically oxidized by horseradish peroxidase (HRP) and further coupled with GA simultaneously, thus forming a covalent cross-linked network on the fiber surfaces. Furthermore, the durable MXene-based textile was used to manufacture smart dual-driven thermal devices with temperature monitoring, which can judge the real-time temperature during heating by changes in its apparent color. More importantly, the textile with smart temperature visualization also offers good EMI shielding and superior UV resistance, while retaining its inherent moisture-wicking, breathable and softness. The present work provides a new insight for the preparation of MXene-based multifunctional textile, and the smart visualization of dual-driven heating shows promising applications in practical personal thermal management.
研究领域:
材料科学
·
生物化学
·
纺织工程
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产品关联
DOI
PubMed
高影响因子
MATERIALS LETTERS
·
2023
·
IF 3
Wenjun Wang,Xiaoming Qi,Fukang Yang,Zhaomeng Long,Shuolei Wang,Xiaojian Jiang,Ziyue Zhang,Yubing Dong
In the present work, we prepared ethylene vinyl acetate@polypyrrole (EVA@PPy) composites that can be realized with electro-thermal dual driven by hot pressing and in-situ polymerization. The fabricated composites can reach a conductivity of 0.2452 ± 0.0153 S/cm and can be warmed up to more than 90 °C in 9 s under a direct current (DC) voltage of 35 V. EVA surface coating PPy layer with EVA backing has good bonding fastness, and the composites also have good dynamic stability and abrasion resistance on the basis of retaining EVA shape memory performance.
研究领域:
材料科学
·
智能材料
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DOI
高影响因子
Advanced Fiber Materials
·
2023
·Vol. 5
·期 6
·2080-2098
·
IF 16.1
Yan Biaobiao,Bao Xueming,Gao Yilei,Zhou Man,Yu Yuanyuan,Xu Bo,Cui Li,Wang Qiang,Wang Ping
Two-dimensional transition metal carbide/nitride (MXene)-based textiles have been developed in many fields; however, the high sensitivity to oxidation and weak interfacial bonding hinder their applications. Herein, we present a strategy for the preparation of a highly antioxidative MXene@gallic acid (MXene@GA, MG) hybrid dispersion, and further covalently grafted it onto carboxylated cotton fabric through interaction with metal ions (Fe 3+ ) for fabricating wearable multifunctional textiles. Due to the cross-linking effect of Fe 3+ and the remarkable antioxidant activity of natural polyphenol GA, the MG coatings firmly adhere to the textile surfaces and can withstand conventional washing, exhibiting favorable service stability and potential application prospects. Moreover, the obtained MG-decorated textile has the inherent characteristics of good breathability, moisture permeability, flexibility, and biocompatibility of the original fabric, which are conducive to the wearability of smart devices. Furthermore, by utilizing the outstanding conductivity (~ 330 S/m) and photothermal convertibility of the MG coating, the functional textile achieves high electromagnetic interference (EMI) shielding efficiency (~ 35 dB), excellent dual-driven ( Joule and solar) heating warmth retention, and infrared thermal camouflage. Due to the green and scalable preparation process, favorable durability, excellent comfort, and multifunctionality, the MG-decorated textiles are anticipated to be promising candidates for the next generation of smart wearable personal protective clothing. Graphical Abstract
研究领域:
材料科学
·
纺织工程
·
智能可穿戴设备
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产品关联
DOI
高影响因子
ChemNanoMat
·
2021
·Vol. 7
·期 4
·483-487
·
IF 3.154
Sihao Pan,Jiaoyu Ren,Enhui Ma,Ke Wang,Sicheng Yang,Hong Wang
Graphical Dual-propelled sporopollenin-exine-capsule (SEC) micromotors loaded with horseradish peroxidase (HRP) have been developed towards on-site degradation of organic pollutants. Near-infrared (NIR) light is employed to trigger the rupture of the magnetic polydopamine (PDA) outer coating and release the platinum-coated SECs loaded with HRP enzyme. Towards on-site degradation of organic pollutants, dual-propelled sporopollenin-exine-capsule (SEC) micromotors loaded with horseradish peroxidase (HRP) have been developed. The magnetic propulsion of SEC micromotors enables them to follow predesignated paths to arrive the pollution site, while the chemical propulsion on the site accelerates the degradation process taking advantage of the fluid mixing effect induced by their movement and bubble generation. Near-infrared (NIR) light is employed to trigger the rupture of the magnetic polydopamine (PDA) outer coating and release the platinum-coated SECs loaded with HRP enzyme. The dual propulsion system combined with the biocompatible nature of the components paves the way for on-site bioremediation of organic pollutants.
研究领域:
环境科学
·
生物医学工程
·
材料科学
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Qi Zhang,Dong Liu,Wei Pan,Haiyan Pei,Kunlun Wang,Shengang Xu,Yingliang Liu,Shaokui Cao
The multifunctional photoelectronic devices are recently attracting much more attention due to their potential enlarged applications. The flexible stretchable electrothermally/photothermally dual-driven heaters for all-weather wearable thermal management are presented in this work with nano-embedded hierarchical Cu x S-coated PET fabrics. Herein, the hierarchical nano-embedded Cu x S film is fabricated via a simple chemical bath method for high electrical conductivity and highly efficient inelastic collision of electro/photo-generated carriers. The hierarchical nano-embedded Cu x S morphology produces the low sheet resistance of 1.26 Ω sq -1 and the super low total heat transfer coefficient of 3.256 × 10 -5 W/ o C·mm 2 , which lead to the high-efficient electro/photo-dual-driven heating effect in the Cu x S@PET fabrics. The saturated temperature on the as-fabricated flexible wearable heaters reaches up to 172 °C. The thermal conversion devices also bear the excellent stability, reproducibility, stretchability, controllability and corrosion-resistant characteristics. Interestingly, their excellent thermal conversion performance could be achieved by freely exchanging the driving power sources, such as electricity-supplying equipment, 635-nm laser, infrared physiotherapy lamp and solar simulator, which provides a necessary precondition for the all-weather applications of flexible wearable heaters. The as-fabricated electro/photo-dual-driven heaters on the Cu x S@PET fabrics have the promising applications in wearable electronics, all-weather self-heating facilities, out/in-vivo physiotherapy, and so on.
研究领域:
材料科学
·
光电功能器件
·
可穿戴技术
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产品关联
DOI
PubMed
高影响因子
SENSORS
·
2021
·Vol. 21
·期 6
·1972
·
IF 3.576
Shidai Tian,Shijie Li,Yijie Hu,Wei Wang,Aifang Yu,Lingyu Wan,Junyi Zhai
There are numerous works that report wirelessly controlling the locomotion of soft robots through a single actuation method of light or magnetism. However, coupling multiple driving modes to improve the mobility of robots is still in its infancy. Here, we present a soft multi-legged millirobot that can move, climb a slope, swim and detect a signal by near-infrared irradiation (NIR) light or magnetic field dual actuation. Due to the design of the feet structure, our soft millirobot incorporates the advantages of a single actuation mode of light or magnetism. Furthermore, it can execute a compulsory exercise to sense a signal and analyze the ambience fluctuation in a narrow place. This work provides a novel alternative for soft robots to achieve multimode actuation and signal sensing.Keywords:soft millirobot;multi-legged;actuator;light-driven;magnetic response
研究领域:
机器人技术
·
材料科学
·
生物医学工程
·
传感器
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）