Materials Chemistry Frontiers
·
2025
·
IF 6.4
Yonglang Yu,Ping Yuan,Zhengyi Fu,Zhaoyong Zou
Crystallization within small volumes rather than bulk solutions is a common phenomenon found during materials synthesis and biomineralization processes. However, the driving forces for mass transport and crystallization under confined environment remain elusive. Here, inspired by the intrafibrillar collagen mineralization process, we investigate the infiltration and crystallization mechanisms of fluorapatite (FAP) within confined channels by comparing anodic aluminum oxide and track-etched template with different surface properties. The results demonstrate that, similar to intrafibrillar collagen mineralization, the capillary force, along with specific interaction between confined channel surface and mineral precursors, is the main driving force for initial infiltration of liquid precursors into confined channels, leading to the nucleation FAP nanocrystals on the surface of channels. We elucidate the critical role of negatively charged polyacrylic acid in promoting the formation liquid precursors for successful infiltration into confined channels and controlling the crystallization kinetics within channels. The formation of FAP nanorods proceed by further promoting the ion diffusion via a concentration gradient resulted from the lower local concentration surrounding FAP crystals. Furthermore, FAP nanocrystals exhibit progressive alignment along the channel direction during subsequent crystal growth stage and ultralong FAP nanorods with a length of more than 25 μm could be obtained. The collective findings underscore the pivotal role of the structure and surface properties of nanoscale confined environment in controlling the infiltration and crystallization pathways of inorganic crystals and establish a foundation for controlled synthesis of biomimetic materials under confinement.
研究领域:
材料科学
·
生物矿化
·
仿生合成
✓ 已验证
产品关联
DOI
高影响因子
Research
·
2025
·
IF 10.7
Shaobo Ding,Junmin Liu,Jiaxu Dong,Rencheng Zhuang,Enbo Shi,Shutong Wang,Yuhang Xiao,Dekai Zhou,Longqiu Li,Xiaocong Chang
Temperature measurement in confined environments has long been a substantial challenge. Due to poor accessibility to constrained space, and low visibility, conventional thermometry and existing nanoscale thermometers struggle to achieve efficient and accurate temperature detection. As an emerging technology, microrobots offer great potential for temperature sensing in such challenging conditions. Here, we propose a temperature-responsive microrobot (TRM) that integrates artificial neural networks into microscale thermal sensing, enabling quantitative temperature measurement in complex and constrained environments. The TRM undergoes irreversible color changes in a high-temperature range of 160 to 240 °C. It features a Janus structure composed of a Cu(NH 3 ) 4 SO 4 -based thermochromic material and a nickel-coated magnetic actuation layer, allowing reliable operation in nontransparent and geometrically confined environments such as porous geological structures and constrained microspaces. The thermochromic mechanism and motion dynamics of the TRM under elevated temperatures were systematically investigated. The microrobot exhibits distinct chromatic responses at different temperatures. Based on the correlation between chromaticity and temperature, a multilayer perceptron neural network was developed. By inputting the observed color features into the trained model, the surrounding temperature can be quantitatively determined. Experimental results in a simulated porous microchannel model confirmed the feasibility and effectiveness of the TRM for localized high-temperature detection. This work provides a new solution for temperature sensing in restricted environments and lays a solid foundation for the application of microrobots in industrial high-temperature monitoring, highlighting their potential for real-world deployment in complex conditions.
研究领域:
微纳机器人技术
·
传感器技术
·
材料科学
·
人工智能应用
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical Science
·
2023
·Vol. 14
·期 14
·3782-3788
·
IF 8.4
Ruihe Yu,Lin Liu,Liying Yin,Yege Jing,Ning Zhang,Hang Bian,Guangshan Zhu
The growth of porous aromatic frameworks (PAFs) on the surface of polymer brushes is reported for the first time. In contrast to PAFs formed in solution, polymer brushes provide a confined environment for PAF growth, resulting in nanosized and homogeneous spherical PAFs formed amongst the polymer brushes. 4-Bromobenzene functionalities from the polymer brushes are utilized to induce PAF growth by a Yamamoto-type Ullman coupling reaction. The size of PAFs can be tailored from 30 nm to 500 nm by subtly changing the structural parameters: e.g. reaction time, grafting density, and concentration of 4-bromobenzene on the surface. The established strategy is not only applicable to the preparation of PAF-1, but can also be extended to the controlled preparation of PAF-5. In addition, free-standing and flexible PS/PAF-1 hybrid membranes are obtained via dissolving the oxidized layer between the polymer layer and the silicon substrate, which can be transferred to any flat substrate. The obtained PS/PAF-1 membrane is proven to show high efficiency in removing dye from water and is promising for eliminating other foulants, such as microorganisms and trace organics.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
PubMed
高影响因子
LAB ON A CHIP
·
2024
·Vol. 24
·期 7
·2122-2134
·
IF 6.1
Meiying Zhao,Ye Tao,Wenshang Guo,Zhenyou Ge,Hanqing Hu,Ying Yan,Chaoxia Zou,Guiyu Wang,Yukun Ren
Soft actuators capable of remote-controlled guidance and manipulation within complex constrained spaces hold great promise in various fields, especially in medical fields such as minimally invasive surgery. However, most current magnetic drive soft actuators only have the functions of position control and guidance, and it is still challenging to achieve more flexible operations on different targets within constrained spaces. Herein, we propose a multifunctional flexible magnetic drive gripper that can be steered within complex constrained spaces and operate on targets of various shapes. On the one hand, changing the internal pressure of the magnetic gripper can achieve functions such as suction or injection of liquid and transportation of targets with smooth surfaces. On the other hand, with the help of slit structures in the constrained environment, by simply changing the position and orientation of the permanent magnet in the external environment, the magnetic gripper can be controlled to clamp and release targets of linear, flaked, and polyhedral shapes. The full flexibility and multifunctionality of the magnetic gripper suggest new possibilities for precise remote control and object transportation in constrained spaces, so it could serve as a direct contact operation tool for hazardous drugs in enclosed spaces or a surgical tool in human body cavities.
研究领域:
生物医学工程
·
微创手术技术
·
智能材料与器件
✓ 已验证
DOI
高影响因子
TALANTA
·
2023
·
IF 6.1
Jingyi Dong,Xia Qiu,Mimi Huang,Xiaohu Chen,Yongxin Li
Solid-nanopores/nanopipettes have the exquisite ability to reveal the changes in molecular volume due to the advantages of adjustable size, good rigidity and low noise. Herein, a new platform for sensing application was established based on G-quadruplex-hemin DNAzyme (GQH) functionalized gold-coated nanopipettes. In this method, GQH was immobilized on gold-coated nanopipette, which could be used as a catalyst for the reaction of H 2 O 2 with 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) to promote the conversion of ABTS to ABTS + ions inside gold-coated nanopipette, and the change of transmembrane ion current could be monitored in real time. At the optimal conditions, there was a correlation between the ion current and the concentration of H 2 O 2 in a certain range, which could be used for the hydrogen peroxide sensing. The GQH immobilized nanopipette provides a useful platform to investigate enzymatic catalysis in confined environment, which can be used in electrocatalysis , sensing and fundamental electrochemistry .
研究领域:
纳米技术
·
生物化学
·
分析化学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 26
·3240-3250
·
IF 3.1
Ruihua Tang,Xueyan Yan,Min Li,Aoqi Du,Hui Yang,Huancai Yin,Mingyue Xie
Nucleic acid detection technologies have been widely utilized for various diseases. Conventional laboratory tests are less suitable for use in resource-limited settings as they are time-consuming, high-cost, complex, and heavily dependent on benchtop equipment. Rapid nucleic acid detection methods that consist of rapid nucleic acid extraction steps could overcome these challenges. A paper-based platform has been utilized to develop various rapid nucleic acid extraction methods owing to its cost-effectiveness, portability, and easy-modification. However, the existing paper-based nucleic acid extraction technologies mainly focus on improving the adsorption capacity of nucleic acids without reducing the non-specific adsorption capacity of proteins. In this study, paper-based nucleic acid extraction technology with wash-free, elution-free, and low protein adsorption was developed. The fabrication of paper involves the mixing of polyethylene glycol (PEG)-modified cotton fiber, chitosan (COS)-modified cotton fiber, and cotton fiber to form PEG-modified cotton fiber/chitosan-modified cotton fiber/cotton fiber (PEG-CF/COS-CF/CF) paper by the wet molding method. The result showed that PEG-CF/COS-CF/CF paper has a desirable pore size (23.9 ± 4.03 μm), good mechanical strength (dry: 9.37 Mpa and wet: 0.28 Mpa), and hydrophilicity (contact angle: 42.6° ± 0.36°). NH3+ groups of COS and OH− groups of PEG were observed on its surface and the adsorption efficiency of nucleic acid in TE buffer was 42.48% ± 0.30%. The limit of detection of pure DNA with this PEG-CF/COS-CF/CF paper by qPCR was as low as 25 ng. Additionally, this platform could successfully extract nucleic acid from 30 μL of a saliva sample, highlighting its potential use for clinical sample testing. The proposed paper-based nucleic acid extraction platform shows tremendous potential for disease diagnosis in resource-limited settings.
研究领域:
生物技术
·
分子生物学
·
诊断技术
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MACROMOLECULES
·
2018
·
IF 5.914
Jinqiao Xue,Wei Bai,Hanyi Duan,Jingjing Nie,Binyang Du,Jing Zhi Sun,Ben Zhong Tang
We studied the aggregation-induced emission (AIE) phenomenon in a nanoconfined environment, where the AIE-active molecule, namely, 1,1,2,2-tetrakis(4-methanoylphenyl)ethane (TPE-4ALD), was held in space via four acylhydrazone bonds within the thermosensitive microgel networks. The thermosensitive microgels, namely N-AH-TPE, were synthesized via the copolymerization of N-isopropylacrylamide (NIPAM) and 4-acylhydrazine-(2-hydroxy-3-(methacryloxypropyl)pyridine hydrochloride (AH monomer) with TPE-4ALD as cross-linker via surfactant free emulsion polymerization (SFEP) in aqueous solution at 70 °C. Acylhydrazone-bonded tetraphenylethene (TPE-4AH) moieties were thus constructed and worked as the fluorophore in N-AH-TPE microgels. The aqueous suspensions of N-AH-TPE microgels exhibit strongly bluish-green fluorescence under ultraviolet excitation because the four arms of TPE-4AH moieties were held and their intramolecular motions are strongly restricted. It is estimated that there is one TPE-4AH moiety per about 394 nm3 for the swollen N-AH-TPE microgels. The fluorescent properties of N-AH-TPE microgels can be modulated via the change of hydrophilic and hydrophobic environments of TPE-4AH moieties exerted by external stimuli, like addition of various good solvents for TPE-based structures, i.e., N,N-dimethylformamide (DMF), methanol, ethanol, tetrahydrofuran (THF), and N,N-dimethyl sulfoxide (DMSO), varying the solution temperature as well as the counteranions of the microgels. An unusual enhancement in the fluorescent intensity is observed when specific amounts of organic solvent are added into the aqueous suspensions of N-AH-TPE microgels, which can be attributed to the cononsolvency of the polyNIPAM network chains. The shrinkage of N-AH-TPE microgels caused by the cononsolvency effect further strengthens the confinement of TPE-4AH moieties and hence enhances the fluorescent emission of the microgels even though the organic solvents added are good solvents for TPE-4AH. Increasing the solution temperature of N-AH-TPE microgels or introducing hydrophobic counteranions into the microgels also significantly enhances the fluorescent emission of the microgels.
研究领域:
材料科学
·
化学
·
高分子科学
·
纳米技术
·
光学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）