Developing an oral fibrous barrier membrane that prevents bacterial invasion while possessing antibacterial properties and facilitating fluid decompression remains a significant clinical and scientific challenge. In this study, we developed a novel Janus membrane by modifying a polypropylene (PP) fibrous membrane with dopamine and zinc oxide nanoparticles (ZnO-NPs). Fabricated via a simple floating immersion method, this asymmetric bilayer structure consists of a hydrophobic PP layer and a hydrophilic PP/dopamine@30 nm ZnO layer, providing both antibacterial properties and enhanced fluid filtration. The mechanical properties of the PP/ZnO membrane were significantly enhanced, with an increase in the Young’s modulus and ultimate tensile strength, indicating improved strength. Antibacterial activity againstStreptococcus mutans(S. mutans) demonstrated a significant reduction in biofilm formation on the PP/dopamine@30 nm ZnO surface compared to unmodified PP. Water flux tests confirmed a stable, high filtration rate, with increased permeability under rising pressure. In vivo experiments with miniature pigs confirmed reduced bacterial presence on the sterile side of the membrane. These findings highlight the potential of the membrane for oral exudate filtration, extending filtration time and minimizing infection risks under strict sterility conditions. Further improvements in barrier properties are necessary to optimize its clinical performance.
Chun-Han Lu,Yi-Ting Tsai,Tzong-Liang Tsai,Ting-Shan Chan,Xuejie Zhang,Chun Che Lin
The analysis of human body composition and food composition requires high-efficiency broadband near-infrared (NIR) lighting sources to achieve a portable, appropriately sized equipment. Herein, we develop a whitlockite-type NIR phosphor Sr9Sc(PO4)7:Cr3+ with an emission centered at 860 nm and full width at half-maximum of 147 nm. Due to the structural characteristics of the matrix, the 60 mol % Cr3+ substitution at the Sc3+ sites gives an internal quantum efficiency up to 56.5%. By replacing Sr with Ba and Ca, we observe a nontypical spectral shift phenomenon and discuss the influence of the second-sphere effect on octahedral Cr3+ ions. To evaluate the diagnostic application, we design a NIR ceramic device with a high optical power of 27.38 mW and high heat dissipation, which can decrease surface working temperature by nearly 50 °C for digital intraoral application. This study provides the research of the second-sphere coordination effect for selective octahedral sites such as Ca, Sr, and Ba coordinated by O atoms on a whitlockite-type crystal. Furthermore, the device promotes a nonionizing solution for detecting dental caries, tooth calcification, and diagnostic application.
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