JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2023
·
IF 6.1
Wenjing Liu,Xiaoxiang Hu,Linghao Fang,Yujie Cai
Spermidine is a naturally occurring polyamine with multiple biological activities and potential food and agricultural applications. However, sustainable and scalable spermidine production has not yet been attained. In this study, a homospermidine synthase (HSS) from Pseudomonas frederiksbergensis (PfHSS) capable of catalyzing the synthesis of spermidine from 1,3-diaminopropane and putrescine was identified based on multiple sequence alignment using Blastochloris viridis HSS (BvHSS) as a template. The optimal reaction pH and temperature for purified PfHSS were determined to be 8.5 and 45 °C, respectively, and K+ was able to promote the enzyme activity. Further analysis of the structural and functional relationships through molecular docking and molecular dynamics simulation indicates that glutamic acid at position 359 is the essential residue for the enzyme-catalyzed synthesis of spermidine. The whole-cell catalytic reaction yielded 1321.4 mg/L spermidine and 678.2 mg/L of homospermidine. This study presents a novel, promising, and sustainable biological method for producing spermidine.
研究领域:
生物化学
·
合成生物学
·
食品科学
·
农业科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Xugang Dang,Heng Qiu,Shuguang Qu,Shuang Liang,Lianxiang Feng,Xuechuan Wang
This study aimed to pioneer the development of an innovative, eco-friendly, and chrome-free tanning agent, with a focus on promoting sustainable practices in ecological leather production. Two novel biomass-derived tanning agents, namely, β-TCD and β-GCD, were synthesized through a one-pot grafting process involving environmentally friendly epoxy monomers: triglycidyl isocyanurate (TGIC) and glycerol triglycidyl ether (GTE). Characterization through various analytical methods, including FTIR, 1H NMR, XPS, GPC, SEM, and TGA, confirmed the successful grafting of TGIC and GTE onto β-cyclodextrin (β-CD) backbones. The resulting β-TCD and β-GCD exhibited notable epoxide values of 0.349 and 0.388 mol/100 g, respectively, along with a broader molecular weight distribution of intermediates. These newly developed tanning agents, β-TCD and β-GCD, were then applied in depickling goatskin tanning experiments. Results indicated that the crust leather tanned with β-TCD and β-GCD displayed favorable thermal stability, with shrinkage temperatures reaching 84 and 82 °C, respectively. Moreover, the thickening rates of the leather exceeded 40%. The crust leathers tanned with β-TCD, and β-GCD demonstrated excellent physical and mechanical properties, as well as notable resistance to yellowing compared to conventional commercial chrome-free tanning agents like TWS and F-90. Overall, this research emphasizes the efficacy of natural cyclodextrin materials as potent and environmentally friendly alternatives to chromium-based tanning agents, showcasing their significant potential in advancing sustainable and cleaner practices in leather production.
研究领域:
材料科学
·
环境科学
·
皮革化学
✓ 已验证
产品关联
DOI
高影响因子
VIEW
·
2022
·Vol. 3
·期 5
·20220031
·
IF 0
Shenglong Wang,Boling Lan,Yuyu Gao,Yanting Xie,Hanyu He,Da Xiong,Guo Tian,Tao Yang,Junfeng Huang,Yong Ao,Yue Sun,Weiqing Yang,Weili Deng
MXenes have received tremendous attention for flexible electronics owing to their excellent conductivity, water dispersibility, and mechanical flexibility. However, the sediment from the MXene production process is usually discarded as trash, resulting in low utilization. Here, we present a flexible pressure sensor that enables micro-force sensing and efficient utilization of MXene by confining MXene trash among structured MXene electrodes. Benefiting from the synergistic effect of both the confined micro-conical structure and easily changeable space of MXene trash, the as-designed device can detect extremely subtle pressure of 2.9 Pa, deliver a high sensitivity over 4.08 kPa −1 , and exhibit a remarkably fast response time (7 ms). These properties make it suitable for monitoring weak force signals from human wrist pulse and even for detecting dynamic responses associated with acoustic waves. This work provides a reference for the versatile and efficient application of MXene in the same device, showing great potential for sustainable production of next-generation wearable smart electronics.
研究领域:
材料科学
·
柔性电子
·
传感器技术
✓ 已验证
产品关联
DOI
AICHE JOURNAL
·
2025
·
IF 4
Xue Gao,Lei Zhang,Shaohuang Chen,Mei Cui,Renliang Huang,Wei Qi,Rongxin Su
The commercial application of phosphorylated cellulose nanofibrils (PCNFs) is restricted by the high environmental burdens and production costs. In this study, we developed an integrated process incorporating solvent-free phosphorylation and recycled filtrate-based phosphorylation for sustainable production of PCNFs. The phosphorylation process consisting of solvent-free ball milling and heat curing was optimized, and the obtained PCNFs showed high charge content (3.78 mmol/g) and ultrafine diameter (~2.2 nm). The washing filtrates were recycled as the aqueous solutions used in heat soaking-based phosphorylation, which could be regarded as the substitute of pure urea and phosphates. Moreover, this integrated phosphorylation process exhibited enhanced environmental friendliness with an average reduction ratio of 14.7% across all impact categories, and the production cost decreased by 31.7% compared with the traditional production route, as the life cycle assessment and techno-economic analysis results revealed. This integrated process offers valuable guidance for the sustainable industrial-scale production and efficient commercialization of PCNFs.
研究领域:
材料科学
·
环境科学
·
化工技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
·
IF 9.224
Lei Zhang,Jingyu Wang,Renliang Huang,Mei Cui,Wei Qi,Zhimin He,Rongxin Su
Cellulose nanocrystals (CNCs) are renewable and multifunctional plant-based nanoparticles that are industrially produced by controlled sulfuric acid hydrolysis, resulting in a large amount of acid–sugar mixture, which has potential to be recovered and concentrated for reuse. However, the removal of sugar from the acid–sugar mixture, which was produced by cellulose biomass hydrolysis, is essential before acid recycling. In this study, the acid–sugar mixture was separated from the CNC hydrolysate, and then, a combination process of diffusion dialysis (DD) using anion-exchange membranes and electrodialysis (ED) was used to remove the sugar from the acid–sugar mixture. The operation parameters were optimized and Fenton oxidation (FO) was applied to degrade sugar with a decrease in the chemical oxygen demand (CODCr) in the wastewater. As a result, 98.8% sulfuric acid was totally recovered in a practical process, with 92.2% recovery by diffusion dialysis and 87.1% by electrodialysis, and more than 90% sugar was rejected. CODCr in the wastewater decreased to <500 mg/L by FO treatment. Furthermore, CNCs prepared with the recovered sulfuric acid showed a crystallinity, surface charge, and morphology similar to that prepared with fresh acid. Therefore, this combination process of DD and ED is a green and economic feasible way for acid recycling for sustainable CNC production.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
·
IF 9.224
Shaohuang Chen,Ning Ren,Mei Cui,Renliang Huang,Wei Qi,Zhimin He,Rongxin Su
Phosphorylated cellulose nanofibrils (PCNFs) made from woody biomass have aroused immense interest because of their promising applications in various fields, including flame retardancy, adsorption, and separation. However, traditional production methods show high chemical and energy consumption, while the obtained PCNFs have lower charge density. In this study, PCNFs with higher charge density (2.09–3.79 mmol·g–1) were produced by tuning heat soaking pretreatment of cellulose fibers in phosphate salt and urea solutions, followed by curing and mechanical fibrillation. An optimized pretreatment can be achieved by heat-assisted soaking at 80 °C for 25 min, which was effective to produce PCNFs with greater performance (e.g., higher charge and crystallinity) compared to those of traditional methods. Furthermore, the optimized route is more sustainable with a substantial decrease in resource consumption including chemicals (33.6%), water (55.8%), and energy (65.3%), and the production costs would be saved by 62.0% in comparison with the traditional route. Such a sustainable and economic process has great potential in the industrial production of PCNFs.
研究领域:
材料科学
·
绿色化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Kangyu Liu,Bingzhang Shao,Haichao Liu,Jinlong He,Aiguo Zheng,Genghong Li,Bo Zheng,Zeyang Li,Wei Liu,Xuefeng Li,Baoning Zong
Antibacterial monomers are prerequisites for synthesizing antibacterial polymers, especially during the current COVID-19 pandemic. Dimethyl-protected cyclic lysine (DMCL) is a promising functional monomer for nylon-6 based self-cleaning antibacterial polymers. However, the production of DMCL still faces formidable challenges, such as harsh reaction conditions and low catalyst activities. In this study, we developed a Pd/ m -Al 2 O 3 -Si catalyst, which exhibited high efficiency in converting α -amino- ε -caprolactam ( α -ACL) to DMCL, affording a yield of as high as 97.1% at 100 °C and 1 MPa H 2 . The lack of Brönsted acid sites on the catalyst surface facilitated the formation of DMCL and suppressed undesirable hydrolysis or cracking by-products from the lactam-based reactant. The recycled experiments showed that Pd/ m -Al 2 O 3 -Si performed excellent stability and physical strength with essentially no damage to its microspheres after the reaction. The nylon‑6 copolymers produced from the as-synthesized DMCL exhibited similar structure and thermal stability with pure nylon-6, showing great potential in synthesizing the self-cleaning antibacterial polymers. This work provides a sustainable and efficient method for producing DMCL and other lysine-based antibacterial monomers, showing a great prospect for the utilization of bio-based chemicals in synthesizing functional polymers.
研究领域:
有机化学
·
材料科学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2023
·
IF 11.4
Yanfeng Wang,Peiyun Wei,Zihan Shen,Chao Wang,Jie Ding,Wenkai Zhang,Xin Jin,Chad D. Vecitis,Guandao Gao
Hydrogen peroxide (H2O2), as a critical green chemical, has received immense attention in energy and environmental fields. The ability to produce H2O2 in earth-abundant water without relying on low solubility oxygen would be a sustainable and potentially economic process, applicable even to anaerobic microenvironments, such as groundwater treatment. However, the direct water to H2O2 process is currently hindered by low selectivity and low production rates. Herein, we report that poly(tetrafluoroethylene) (PTFE), a commonly used inert polymer, can act as an efficient triboelectric catalyst for H2O2 generation. For example, a high H2O2 production rate of 24.8 mmol gcat–1 h–1 at a dosage of 0.01 g/L PTFE was achieved under the condition of pure water, ambient atmosphere, and no sacrificial agents, which exceeds the performance of state-of-the-art aqueous H2O2 powder catalysts. Electron spin resonance and isotope experiments provide strong evidence that water–PTFE tribocatalysis can directly oxidize water to produce H2O2 under both anaerobic and aerobic conditions, albeit with different synthetic pathways. This study demonstrates a potential strategy for green and effective tribocatalytic H2O2 production that may be particularly useful toward environmental applications.
研究领域:
化学
·
环境科学
·
能源
✓ 已验证
产品关联
DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2024
·
IF 9.3
Lin Fan,Shangshang Sun,Zhidan Zhang,Yanmei Qin,Peter Ruhdal Jensen,Chun You
In conjunction with the pressing global issue of climate change and the associated concern over global warming, increasing interest has emerged in the exploration of carbon dioxide (CO2) as a resource for the generation of a diverse array of products intended to serve societal needs. This study presents the development of an ATP-free and NAD-balanced in vitro synthetic enzymatic biosystem (ivSEB), which comprises only five cascade thermophilic enzymes, designed for the synthesis of L-malate through CO2 fixation powered by the utilization of D-glucose as a substrate. This designed ivSEB yields two moles of L-malate from one mole of D-glucose and two moles of CO2. Through meticulous refinement of reaction conditions and enzyme loading amounts, this ivSEB has demonstrated its capability to produce 6.85 mM of L-malate via CO2 fixation from an initial 5 mM of D-glucose with a molar product yield of 68.5%, and 2.45 mM of L-lactate as a byproduct. In the pursuit of assessing the industrial feasibility of this ivSEB, the study further subjected the system to the utilization of a high concentration (45.70 mM) of D-glucose. Although this endeavor necessitates additional optimization for enhanced efficiency, the present findings herald the emergence of an alternative avenue for the sustainable production of L-malate through CO2 fixation, thus bearing substantial promise for addressing ecological and industrial imperatives.
研究领域:
生物技术
·
环境科学
·
化学工程
·
可持续化学
·
酶学
✓ 已验证
DOI
高影响因子
Microbial Cell Factories
·
2022
·Vol. 21
·期 1
·1-9
·
IF 6.352
Wang Yingying,Chen Xueman,Chen Qiaoyu,Zhou Ning,Wang Xin,Zhang Alei,Chen Kequan,Ouyang Pingkai
Background l-Tryptophan (l-Trp) derivatives such as 5-hydroxytryptophan (5-HTP) and 5-hydroxytryptamine (5-HT), N-Acetyl-5-hydroxytryptamine and melatonin are important molecules with pharmaceutical interest. Among, 5-HT is an inhibitory neurotransmitter with proven benefits for treating the symptoms of depression. At present, 5-HT depends on plant extraction and chemical synthesis, which limits its mass production and causes environmental problems. Therefore, it is necessary to develop an efficient, green and sustainable biosynthesis method to produce 5-HT.Results Here we propose a one-pot production of 5-HT from l-Trp via two enzyme cascades for the first time. First, a chassis cell that can convert l-Trp into 5-HTP was constructed by heterologous expression of tryptophan hydroxylase from Schistosoma mansoni (SmTPH) and an artificial endogenous tetrahydrobiopterin (BH4) module. Then, dopa decarboxylase from Harminia axyridis (HaDDC), which can specifically catalyse 5-HTP to 5-HT, was used for 5-HT production. The cell factory, E. coli BL21(DE3)△tnaA/BH4/HaDDC-SmTPH, which contains SmTPH and HaDDC, was constructed for 5-HT synthesis. The highest concentration of 5-HT reached 414.5 ± 1.6 mg/L (with conversion rate of 25.9 mol%) at the optimal conditions (substrate concentration,2 g/L; induced temperature, 25℃; IPTG concentration, 0.5 mM; catalysis temperature, 30℃; catalysis time, 72 h).Conclusion sThis protocol provided an efficient one-pot method for converting. l-Trp into 5-HT production, which opens up possibilities for the practical biosynthesis of natural 5-HT at an industrial scale.
研究领域:
生物技术
·
药学
·
代谢工程
·
合成生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 7
·1116-1127
·
IF 7.571
Yarong Lv,Yulong Xu,Xinyu Sang,Chenxi Li,Yong Liu,Quanyi Guo,Seeram Ramakrishna,Ce Wang,Ping Hu,Himansu Sekhar Nanda
The need for a wound dressing material that can accelerate wound healing is increasing and will last for a long time. In this study, cerium oxide nanoparticle (CeNP) incorporated poly-L-lactic acid (PLLA)–gelatin composite fiber membranes were fabricated using established electrospinning techniques for use as a low-cost sustainable wound dressing material. The obtained membranes were characterized for their morphology, and physical, mechanical and biological properties. The results showed that the membranes maintained an integrated morphology, and demonstrated water absorption and improved mechanical properties. An in vitro cell proliferation test confirmed that the cells presented better activities over the composite fiber membranes. In the rat scalding model, rapid wound recombination was observed. All these data suggested that electrospun CeNP incorporated PLLA–gelatin composite fiber membranes can be an ideal dressing substitute that can be used for wound healing applications. Furthermore, the use of biodegradable polymers and environmentally sustainable production technologies presented better sustainability for the commercial production of these composite membranes promoting tissue regeneration and scar remodeling.
研究领域:
材料科学
·
生物医学工程
·
组织工程
·
伤口愈合
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Meichen Zhang,Syed Zaheer Ud Din,Jianzhen Mao,Zongwei Guo,Feng Xu
This study presents a readily synthesized deep eutectic solvent composed of guanidinium hydrochloride and lactic acid (GH/LA) for refining various industrial xylose residues (delignification and non-delignification), addressing industrial challenges caused by the accumulation of residues. Under mild conditions (120 °C for 2 h), lignin was efficiently extracted, leaving cellulose intact in the solid fraction. The isolated cellulose exhibited a theoretical sugar yield of 100 % within 48 h, which was attributed to the optimal lignin content (6.15 %) remaining in the cellulose residue. The recovered lignin demonstrated high purity (93.36–97.95 %), low molecular weight (2786–3089 g/mol), moderate polydispersity (2.29–2.37), remarkable thermal stability, and potent antioxidant activity (IC 50 =1.25 mg/mL). Comprehensive analysis confirms GH/LA DES pretreatment as a simple and effective method for efficient industrial waste utilization.
研究领域:
化学工程
·
生物技术
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）