Journal of Functional Biomaterials
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2026
·Vol. 17
·期 2
·103
·
IF 5.9
Junwei Qin,Hancong Wu,Bifeng Lan,Liucui Yao,Zhenqiang Wu
Developing safe and effective hemostatic materials is critical for rapid bleeding control and wound management. However, traditional hemostatic materials using chemical crosslinking often fall short in hemostatic efficiency and carry risks of secondary injury from reagent residues. This study introduced an irradiation-fabricated composite collagen sponge based on fish skin collagen, chitosan, and soluble starch. The sponge was prepared via material solution blending, followed by cobalt-60 gamma irradiation at various doses, with casting and freeze-drying. Its functionality and safety were systematically evaluated. The results show that low-dose gamma irradiation (1–3 kGy) applied to a precursor solution prior to freeze-drying promoted intermolecular crosslinking, improving mechanical strength, elongation, and biostability, while higher doses (6 kGy) slightly reduced crosslinking due to the partial degradation of collagen, chitosan, and starch. With low-dose irradiation, the proposed hemostatic sponges show enhanced water absorption, blood cell adsorption, swelling, and antibacterial properties, indicating effective hemostatic performance. Spectroscopic characterization confirmed chemical bond modifications with no loss of crystallinity. Cytotoxicity and in vivo tests demonstrated biocompatibility and effective hemostatic performance. Compared with the commercial HSD sponge, the irradiated sponges exhibited superior hemostatic efficacy. This study presents that a collagen-based synergistic matrix prepared by gamma-ray irradiation can produce a hemostatic sponge with enhanced absorbency, bioactivity, and antibacterial properties, highlighting its great potential in rapid hemostasis and wound care applications.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 21.1
Yuqing Feng,Hongxia Liu,Yongxing Shang,Yingsen Fang,Shumei Gao,Ping Sun,Bitao Xiong,Hui Wang,Hui Liu,Mingbao Feng
Single-atom catalysts (SACs) are an effective strategy for maximizing the efficiency and reducing the costs of advanced oxidation processes (AOPs). Herein, a novel SAC with Fe−N 3 C sites was synthesized for emerging periodate (PI)-based AOPs. The optimized catalyst demonstrates superior performance, achieving 100 % removal of diclofenac (DCF) within 20 min via predominant singlet oxygen ( 1 O 2 ). Compared to the Fe−N 4 configuration, the Fe−N 3 C site enables an unprecedented 152.9-fold increase in the pollutant degradation rate, surpassing most reported catalysts. Density functional theory (DFT) calculations reveal that the Fe−N 3 C sites reduce the oxophilicity of the Fe centers, thereby lowering the energy barrier for 1 O 2 desorption and promoting its preferential generation. The DCF degradation pathway was further elucidated by Fukui constants. Furthermore, the Fe−N 3 C/PI system exhibits excellent stability with negligible leaching of Fe ions and strong resistance to common wastewater components. This work provides new insights into the design of efficient SACs and the construction of PI-based AOPs for water decontamination.
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ACS Catalysis
·
2026
·Vol. 16
·期 17
·16958-16971
·
IF 13.6
Xi Yuhan,Hu Xinge,Zhang Jinpan,Xu Yuqing,Feng Qianyue,Cao Liu,Ma Yueru,Li Hai,Yan Tianran,Li Chaoran,Zhang Liang,Feng Kai,He Le,An Xingda
Solar-driven chlorine and hydrogen co-evolution from seawater represents an energy-conservating and clean alternative to the conventional chlor-alkali industry. However, sustained and selective chlorine production remains extremely challenging due to competition from the thermodynamically less demanding water oxidation side reaction. In this work, we demonstrate a Ni/Ni 2 SiO 4 plasmonic matrix catalyst that enables a distinct energetic charge carrier filter effect for wavelength-controlled selective chlorine and hydrogen co-production. Based on the distinct energy band structure, the plasmonic-mediated energetic charge filter drives the extraction of higher-energy “hot” holes and lower-energy “cold” electrons, respectively, through lower- and higher-wavelength photons. This phenomenon, combined with hierarchical plasmon coupling and promoted carrier dynamics, collectively led to the cooperative facilitation of both the oxidative and reducing half reactions. In situ spectroscopic investigations point at preferentially promoted chloride adsorption and activation via a two-step, nonradical chlorine evolution pathway, leading to favorable Cl 2 and H 2 yield rates with near-unity Cl 2 selectivity in photocatalytic measurements with seawater. The plasmon-mediated energetic charge carrier filter mechanism opens intriguing pathways for preferential reaction engineering with effective product control.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Tian He,Shaosong Huang,Ping Chen,Guangzheng Zhuang,Bing Tang,Ping Li,Liying Bin,Yunqiang Yi,Weirui Chen,Laisheng Li
One-step pyrolysis enabled Fe/N co-doping to form CNT-confined Fe 3 C structures; • Fe 3 C-derived Lewis acidic sites served as the primary centers for activating O 3 ; • Fe 2+ /Fe 3+ redox cycling promoted ozone activation and ROS generation; • Confinement enhanced O 3 enrichment, •OH yields, and ion tolerance during FeN-BC/O 3 ; • •OH was confirmed as the key oxidizing species for IBP removal; Active metal leaching, inefficient ozone activation, and limited interfacial mass/electron transfer are key factors restricting the performance of conventional catalytic ozonation catalysts. To address these issues, a biomass-derived Fe/N co-doped carbon nanotubes with a nano-confinement structure (FeN-BC) was synthesized via one-pot pyrolysis of rapeseed straw, FeCl 3 •6H 2 O, and melamine at 700 °C under N 2 followed by acid washing and purification. SEM, TEM, and XRD results revealed that Fe and N co-doping promoted in-situ growth of carbon nanotubes with stable encapsulation of Fe 3 C nanoparticles by graphitic layers. In the catalytic ozonation of ibuprofen (IBP), FeN-BC achieved 91.5% removal within 60 min, outperforming sole ozonation and control catalysts (BC, Fe-BC, N-BC). On account of the synergistic function of Fe and N, the Fe 3 C active center exhibited excellent stability, with iron leaching remaining below 0.1 mg L −1 , whereas Fe-BC released 0.51 mg L −1 iron. In addition, FeN-BC retained good catalytic activity after five consecutive cycles. Furthermore, FeN-BC maintained excellent catalytic stability across pH 3–9 and with various inorganic anions (Cl − , SO 4 2− , NO 3 − , H 2 PO 4 − ). •OH was identified as the dominant reactive species, contributing 86.86% to IBP degradation. Electrochemical and DFT results demonstrated that the nano-confinement effect enhanced interfacial electron transfer, with Fe 3 C Lewis sites serving as the primary active center. IBP degradation followed three pathways, yielding 18 intermediates and accompanied by progressive detoxification. This work advances the understanding of nano-confinement enhanced ozone activation and promotes the development of sustainable biomass-derived catalysts for water purification. Download: Download high-res image (147KB) Download: Download full-size image
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Jilong Lu,Meizhen Xie,Lipin Chen,Qing Song,Siew Yin Chan,Yong-Huan Yun
Iridescent CSM is obtained from shrimp shell by deproteinization, demineralization and deacetylation. • Iridescent CSM is a mesoporous material with Bouligand structure. • CSM exhibited chromatic responsiveness toward aldehydes, ketones and acids. • CSM successfully identified all highly oxidized samples through noticeable color changes. Lipid oxidation is a major cause of food deterioration and can be detected visually using colorimetric sensors. However, existing sensors often involve the use of harmful chemicals or dyes. This study aimed to exploit the potential of structurally colored biomaterials as lipid oxidation sensors. An iridescent chitosan membrane (CSM) with structural color was fabricated from shrimp shells by chemical deproteinization, demineralization and deacetylation. Its responsiveness toward 28 volatile lipid oxidation products was investigated, and its effectiveness as a lipid oxidation sensor was evaluated. The results showed that the CSM exhibited a Bouligand structure. The membrane had a deacetylation degree of 83.97%, a specific surface area of 0.30 m 2 /g, an average pore volume of 0.0006 cm 3 /g, and an average pore diameter of 8.76 nm. It showed visible color changes upon exposure to aldehydes, ketones, and organic acids, with minimum visually discernible concentrations of 14 μmol/L for organic acid, 54 μmol/L for aldehydes and 1085 μmol/L for ketones. Moreover, CSM exhibited excellent structural stability and remained chemo-responsive during one year of storage under room temperature conditions. Eight soybean oil samples derived from the same oil but at different oxidation stages were used for assessing the performance of CSM as a lipid oxidation sensor. Out of the eight oil samples, the CSM correctly identified the oxidation status of seven, showing no color change for fresh samples and visible color changes for oxidized ones. This work demonstrates the potential of the structurally colored CSM as a biocompatible and chemical-free colorimetric indicator for lipid oxidation detection. Download: Download high-res image (225KB) Download: Download full-size image
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Journal of Energy Storage
·
2025
·
IF 9.8
Yongyang Zhu,Shun Wang,Yanwu Chen,Feng Liu,Libing Guo,Yingxi Wei,Guijing Xiao,Qing Zhou,Longwen Chen
The hydrolysis of lithium borohydride (LiBH 4 ) is very promising for on-site hydrogen generation to supply hydrogen since it has appealing features such as a high hydrogen capacity (13.9 wt%, water included), fast hydrogen evolution rate, and mild reaction conditions. The large-scale application of LiBH 4 , however, is restricted by its difficult regeneration from stable hydrolytic products (LiBO 2 · x H 2 O), which requires expensive reducing agents such as MgH 2 , high energy-consuming dehydration process for LiBO 2 ·2H 2 O, and additional hydrogen input. Herein, we develop a facile method to directly regenerate LiBH 4 from LiBO 2 ·2H 2 O by ball milling with low-cost Al-rich alloys as reductants and Li 2 O as additives, balancing efficiency and economy well. Introducing Mg (or Ca) into Al to form Al-rich alloys optimizes the mechanical brittleness and chemical reducibility, which facilitate the crushing, collision, and reaction of reactants and the conversion of H + to H − . The specific mechanism study illustrates that Mg in Al 3 Mg 2 preferentially reacts and the in-situ derived Al with fresh surface and fine size is highly active for reductive regeneration of LiBH 4 . Besides, a little addition of Li 2 O suppresses the formation of “boron sink”, [B 12 H 12 ] − , further increasing the yield of LiBH 4 . This work evidences the regeneration potential of Al-based reducing agents on metal borohydrides.
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COLLOID AND POLYMER SCIENCE
·
2025
·
IF 2.3
Xu Liang,Chen Zekun,Tang Deping,Yin Qingyue,Tao Caihong,Wang Kairong
As bacteria are developing stronger resistance, infections caused by Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) are becoming increasingly difficult to treat. Consequently, the preparation of targeted antibacterial hydrogel materials that possess high injectable mechanical strength as well as excellent antibacterial properties has drawn significant attention in the field of antibacterial research. In this paper, Fe 3 O 4 particles were used as the magnetic core and shielded by a hydrophilic carbon (C) layer. Subsequently, on the surface of the C layer, a mesoporous polydopamine (MPDA) film with favorable biocompatibility was fabricated, and small-sized Ag nanoparticles (Ag NPs) possessing excellent antibacterial performance were modified thereon. Eventually, the above composite nanoparticles were mixed with pure polyvinyl alcohol (PVA) hydrogel to formulate an injectable antibacterial hydrogel. The antibacterial properties of Fe 3 O 4 @C@MPDA@Ag nanoparticles at varying concentrations were evaluated through in vitro experiments. The results demonstrated that the higher the concentration of Fe 3 O 4 @C@MPDA@Ag nanoparticles, the more remarkable the antibacterial effect would be. Moreover, the survival rates of Fe 3 O 4 @C@MPDA nanoparticles and Fe 3 O 4 @C@MPDA@Ag nanoparticles on HL-7702 cells were evaluated via in vitro cytotoxicity experiments. The results showed that the two nanoparticles had good biocompatibility. In addition, the antibacterial properties of Fe 3 O 4 @C@MPDA@Ag@PVA antibacterial hydrogel in mice has been researched. The results indicated that it has good antibacterial properties and wound healing properties.
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Nanoscale
·
2026
·
IF 5.2
Jianbo Jiao,Jianfeng Lan,Guizhen Lu,Zhihui Ou,Jianhui Li,Yifei Sun,Li Zhang,Yanling Yang,Bo Wu,JianHua Wu
Titanium-based metal oxide anodes exhibit strong application potential in chlorine evolution antifouling systems from seawater electrolysis. Conventional dimensionally stable anodes (DSA) rely primarily on Ru- and Ir-based noble metal coatings, yet their large-scale industrial application is hindered by high costs and poor chlorine production efficiency. To overcome the aforementioned shortcomings, Co is introduced into the RuIrTiOx/Ti system, adopting a preparation process involving oxalic acid pretreatment and multi-step coating to fabricate RuIrCoTiOx/Ti electrodes. XRD and TEM results indicate a solid solution coating with uniformly dispersed elements formed on the electrode. The RuIrCoTiOx/Ti electrode demonstrates superior catalytic activity and nearly 84.4% faraday efficiency derived from the chlorine evolution compared to binary or ternary metal oxide-coated counterparts. Remarkably, the electrode maintains over 98.1% of its initial activity after 200 hours of continuous electrolysis. While the slightly reduced durability of RuIrCoTiOx/Ti compared to RuIrTiOx/Ti may be caused by an increased specific surface area of the mixed oxide coating and the formation of higher valence states of Ru species after Co incorporation, as evidenced by SEM and XPS results. This study provides an effective design strategy for developing low-cost, high efficiency DSA electrodes, offering promising prospects for industrial application.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·
IF 6.7
Binhao Wang,Zhaoyue Fan,Jie Zhang,Ulrich Schwaneberg,Ye Ni,Ruizhi Han
Cyclodextrin glycosyltransferase (CGTase) is widely used in stevioside glycosylation, yet achieving precise regioselectivity remains a persistent challenge. Here, 200 ns molecular dynamics (MD) simulations identified residue Y260 in Paenibacillus macerans CGTase as a conformation-sensitive determinant for rebaudioside A (RebA) glycosylation. The Y260N variant achieved exclusive regioselectivity, producing only the C13-glycosylated products of RebA, although with a ∼30% reduction in conversion compared with wild-type. This high regioselectivity extended to other steviol glycosides─Reb C, D, and M─each yielding a single regioisomer. Further MD simulations indicated that conformational reorganization restricts access to O21 and stabilizes Glu258 toward O14, thereby enforcing C13-specific glycosylation. This work elucidates a mechanism for regioselective regulation in CGTase and provides a strategy for engineering other glycosylation enzymes.
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Journal of Food Measurement and Characterization
·
2026
·
IF 3.6
Gao Wenhong,You Qian,Jiang Liyuan,Chang Yu,Zeng Xin-an,Han Zhong
SSPS-Zn chelate was synthesized by soluble soybean polysaccharide (SSPS) and zinc chloride, and its properties were investigated in this paper. SSPS-Zn was easily soluble in deionized water, but not easily soluble in acetone, chloroform and n -butanol at room temperature. The water content and swelling index of SSPS-Zn were 5.52% and 185.00%, respectively. SSPS-Zn also showed good colloidal stability in the pH range of 1–14. In 0–10 mg/mL concentration range, SSPS-Zn exhibited markedly improvement for all four in vitro antioxidant activities (DPPH, •OH, and O 2 ⁻• scavenging, and lipid peroxidation inhibition). SSPS-Zn demonstrated stronger inhibitory effects on α -glucosidase and α -amylase, and superior urea adsorption ability, implying the potential to lower blood sugar and urea toxicity. The SSPS-Zn capsule preparation process was optimized using Response Surface Design. The quadratic polynomial regression model for the yield of capsule granule intermediates was established. The optimal conditions included an ethanol concentration of 77.60%, an MCC content of 38.88%, and a drying temperature of 51.50 °C, achieving a granulation yield of 91.02%. The SSPS-Zn capsules exhibited favorable physicochemical properties, with a repose angle below 30°, an average bulk density of 0.92 g/mL, an average moisture content of 6.22 ± 0.15%, and a critical relative humidity of approximately 66%. Under simulated gastrointestinal conditions, the Zn 2+ release rate reached approximately 41.66% after 40 min, 65.74% after 2 h, and 70.83% after 3 h, indicating a sustainable release behavior. These characteristics suggested that SSPS-Zn capsules have potential as multifunctional organic zinc supplements with antioxidant, hypoglycemic, and detoxifying properties.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhen Zhang,Xiaojian Tian,Yuxiao Sun,Dandan Han,Bang Gu,Dan Wu,Armin Rezayan,Xian Wu,Jingpeng Zhao,Jianshe Wang,Tianliang Lu,Renfeng Nie,Xiaoqin Si,Chunbao Xu,Yongsheng Zhang
Vanadium-based catalysts are widely used in the oxidation of carbohydrates to produce formic acid (FA), a promising liquid organic hydrogen carrier, but still suffers from low yield due to the formation of CO 2 . This study found that the spatially isolated VO x on active carbon (AC) can significantly increase FA yield from 43.5 to 72.9% in glucose oxidation compared with free VO x . Two specific roles of AC were revealed. Firstly, the oxygenated functional groups, high surface area and abundant microporous of AC, play a crucial role in the atomic dispersion of VO x , resulting in a heterogeneous, single-site VO x -AC catalyst. The isolated VO x site favors the oxidative C C bond cleavage in glucose via a stepwise α-cleavage pathway, thus improving FA selectivity. Secondly, the conductive AC acts as an electron buffer, which accelerates the catalytic redox cycle between V 5+ and V 4+ of the isolated VO x sites, thus increasing the reaction activity. The prepared single-site VO x -AC catalyst is reusable and can generate a concentrated FA solution (4.7 wt%) by simple filtration of the solid catalyst. This work presents a simple method for the production of H 2 energy carrier from biomass and provides a fundamental basis for designing efficient catalytic systems for aqueous-phase oxidation reactions.
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ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Rongfan Ren,Minghui Yuan,Hongli Li,David Da Yong Chen
Carbohydrates play critically important roles in energy supply and biological functions in living systems. However, it has been a great challenge to identify saccharides and distinguish their isomers because they have highly similar structures and many possible positions for glycosidic linkages. In this work, an ambient ionization tandem mass spectrometry method was developed to characterize disaccharide structural isomers with in situ methylation. The direct analysis in real time ion source can be used to facilitate the methylation reaction of disaccharides with tetramethylammonium hydroxide. The hydroxyl groups of disaccharides can be methylated instantaneously, and the products can be ionized at the same time. The methylated product ions from full scan mass spectrometry (MS) and tandem MS can be used to distinguish a variety of disaccharide structural isomers with different glycosidic linkages, compositions, and configurations. Characteristic marker ions were discovered, and they can be used for the assignment of linkage type and identification of specific isomeric forms. The method was used for the direct identification of disaccharide isomers from real commercial products such as honey, wine, and milk without complex sample pretreatment or chromatographic separation.
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