COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Xiaoxia Zhang,Ru Song,Xinyan Liu,Yan Xu,Rongbian Wei
Poor water solubility is one of the main adverse factors for vitamin D 3 to be used as a fortifier in water-soluble food system. In this study, a phase transformation based nanoemulsion fabrication process was developed to encapsulate vitamin D 3 with Tween 80 and Span 80 as a composite surface-active surfactant (named as Vit D 3 NEs). The encapsulation efficiency of vitamin D 3 in resultant oil in water nanoemulsions reached 99.9%. The prepared Vit D 3 NEs was spherical with average particle size of 391.47 ± 12.89 nm, polydispersity index of 0.23–0.31, and endothermic temperature of 127.1 ℃. Results of FTIR indicated that hydrophobic, electrostatic and hydrogen bond interactions were involved in Vit D 3 NEs fabrication. Compared to un-encapsulated Vit D 3 (bare Vit D 3 ), Vit D 3 NEs displayed higher stability under gastric digestion, and sustained release under intestinal digestion. The cumulative release of Vit D 3 reached 69% after 5 h of intestinal digestion. Further, Vit D 3 NEs demonstrated stronger thermal stability than the bare Vit D 3 at 40–60 °C, and the first-order kinetics was well fit to describe its thermal degradation . Our work suggests a new insight into the application of Vit D 3 NEs stabilized by Tween 80 and Span 80 in food industry.
研究领域:
食品科学
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生物化学
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产品关联
DOI
高影响因子
Sustainable Materials and Technologies
·
2025
·
IF 9.2
Chengxin Xie,Lanlan Su,Zhendong Deng,Wandi Zhai,Xiangchao Pang,Xiaofeng Hao,Yuan Zhu
The development of sustainable, high-performance adhesives has remained a challenge, hindered by the intrinsic trade-off between eco-friendliness and robust functionality, required for demanding applications. This is particularly true for waterborne polyurethane (WPU) adhesives, whose use in the plywood industry is limited by insufficient mechanical strength and poor water resistance. In this study, a bio-based molecule sorbitan monooleate (SP) was introduced as a dual-function crosslinker to enhance the mechanical and hydrophobic properties of WPU wood adhesives. The unique molecular structure of SP, featuring synergistic polyhydroxyl groups and a long hydrophobic oleic acid chain, was precisely engineered to construct a dense (215.06 mol/m 3 ) three-dimensional network within the WPU matrix, abbreviated as WPU-SP x . This molecular-level design by introducing biomolecule SP yield a dramatic, synergistic enhancement of the final plywood composite's properties. Compared to the unmodified WPU group, the static bending strength and bonding strength of the optimized WPU-SP x plywood was enhanced by 435.7 % and 299.0 %, respectively. Concurrently, the WPU-SP x plywood composite exhibited exceptional dimensional stability against moisture, with its delamination rate and volumetric expansion suppressed to a mere 3.92 % and 0.52 %, demonstrating a remarkable improvement over the unmodified WPU group. This study validates a novel concept where bio-based molecules with designed functionalities can simultaneously enhance the mechanical and hydrophobic properties of polymer networks, offering a scalable and green strategy to generation advanced sustainable materials that meet industrial performance demands.
研究领域:
材料科学
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高分子化学
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胶粘剂与密封剂
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可持续工程
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2021
·Vol. 32
·期 11
·14368-14384
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IF 2.478
Hu Yongcai,Du Zhaofu,Yao Yingbang,Ma Yue,Li Yi,Xu Yiwen,Zhao Xiaobo,Tao Tao,Liang Bo,Lu Shengguo
Silver powders were prepared by a chemical reduction method. Effects of different surfactants during this preparation process were examined. Using these silver powders, silver pastes were prepared for low temperature co-fired ceramics (LTCC) applications. Another batch of different surfactants were added into the silver paste and evaluated. Moreover, various organic thixotropic agents were used to modify the thixotropy behavior of the silver paste. It was found that the surfactants of PVP (Polyvinyl pyrrolidone, for preparation of the silver powder) and Span-85 (for the preparation of silver paste) exhibited the best performance, with an electrical resistivity of 0.11 mΩ mm. The silver paste with the thixotropic agent of hydrogenated castor oil shows the largest thixotropic index of 1.56. Using different organic additives, the microstructural, rheological and electrical properties of the silver paste can be considerably improved, and our results shed light on the optimization of the silver paste for LTCC applications.
研究领域:
材料科学
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化学工程
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电气工程
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DOI
高影响因子
DRUG DELIVERY
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2021
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IF 6.419
Congcong Li,Chaoxi Chen,Yucai Wei,Min Tan,Shuo Zhai,Juebo Zhao,Lu Wang,Tao Dai
It is urgently needed to develop novel adjuvants for improving the safety and efficacy of vaccines. Metal-organic frameworks (MOFs), with high surface area, play an important role in drug delivery. With perfect biocompatibility and green preparation process, the γ-cyclodextrin metal-organic framework (γ-CD-MOF) fabricated with cyclodextrin and potassium suitable for antigen delivery. In this study, we modified γ-CD-MOF with span-85 to fabricate the SP-γ-CD-MOF as animal vaccine adjuvants. The ovalbumin (OVA) as the model antigen was encapsulated into particles to investigate the immune response. SP-γ-CD-MOF displayed excellent biocompatibility in vitro and in vivo. After immunization, SP-γ-CD-MOF loaded with OVA could induce high antigen-specific IgG titers and cytokine secretion. Meanwhile, SP-γ-CD-MOF also significantly improved the proliferation of spleen cells and activated and matured the bone marrow dendritic cells (BMDCs). The study showed the potential of SP-γ-CD-MOF in vaccine adjuvants and provided a novel idea for the development of vaccine adjuvants.
研究领域:
药学
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免疫学
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疫苗学
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产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
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2022
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IF 11.504
Yuan Zhao,Zhongyang Ren,Linfan Shi,Wuyin Weng
The effects of incorporating a water-in-oil pre-emulsion based on different emulsifiers with similar hydrophilic-lipophilic balances on the physicochemical properties of soy protein isolate-based emulsion films were investigated. Confocal laser scanning microscopy images indicated that the oil droplet size in the polyglycerol polyricinoleate and lecithin pre-emulsions was larger than that in the glycerol monostearate, span, and sucrose ester pre-emulsions. By contrast, the oil droplet size in the film-forming emulsions had opposite orders. After drying, the polyglycerol polyricinoleate and lecithin emulsion films contained small and evenly distributed oil droplets and demonstrated a small difference of upper and lower surfaces in oil concentration and contact angle. The water vapor permeability of emulsion films prepared by polyglycerol polyricinoleate and lecithin pre-emulsion was 2.35 × 10 −10 g m −1 s −1 Pa −1 and 2.32 × 10 −10 g m −1 s −1 Pa −1 , respectively, lower than that of other emulsion films. The control emulsion films had the highest tensile strength of 7.43 MPa, whereas polyglycerol polyricinoleate emulsion films had the lowest tensile strength of 4.87 MPa. Furthermore, the polyglycerol polyricinoleate emulsion films had the lowest glass transition temperature among the prepared emulsion films. This study concluded that the properties of film-forming emulsions could be affected by pre-emulsions based on different emulsifiers, resulting in different physicochemical properties of the emulsion films.
研究领域:
食品科学
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材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）