Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Yawen Wu,Xueying Hou,Rui Guo
The presence of tetrachlorobisphenol A(TCBPA) in the environment is continually increasing, which has potential negative effects on human health. Therefore, it is important to develop new materials that can degrade these compounds using various modification techniques. Recently, the photocatalytic degradation of organic pollutants using peroxides has been widely used as the focus of several research studies. This study synthesized Zr-doped NiFe 2 O 4 (Zr-NiFe 2 O 4 ) metal complex materials using a co-precipitation method and applied them to catalyze the degradation of a typical halogenated bisphenol A pollutant using different phase-catalyzed peroxydisulfate (PS) compounds. The results showed that Zr-NiFe 2 O 4 significantly enhances the nitrogen-active adaptive catalytic action between the reactive species and (NH 4 ) 2 S 2 O 8 , exhibiting an excellent catalytic performance (99 %). The degradation rate could reach 90 % after 30 mins with the low concentration of TCBPA (20 mg•L –1 ). Furthermore, the degradation of TCBPA in the Zr-NiFe 2 O 4 /LED/(NH 4 ) 2 S 2 O 8 system occurred over a wide pH range of 3–11. The results of leaching metals were detected that the concentrations of the leached zirconium, nickel and iron ions declined to 0.018 mg•L −1 . In addition, the tri-metal synergistic effect of Zr-NiFe 2 O 4 not only significantly improved the TCBPA removal efficiency, but also enhanced the long-term stability of the composite material. Mechanistic studies revealed that ·OH and SO 4 ·– were involved in the TCBPA degradation process with ·OH being the primary active species, and the possible degradation pathways were deduced using mass spectrometry. The on-line infrared test experiments showed the disappearance of the hydroxyl and double bond within approximately 120 seconds. Moreover, the magnetic properties of Zr-NiFe 2 O 4 met the water recovery requirements, effectively reducing secondary pollution, and aligned with the practical needs for water treatment, providing data for the construction of efficient magnetic catalysts.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2020
·
IF 4.872
Yinan Wang,Wenjuan Zhang,Aijing Li,Maoyong Song
Tetrachlorobisphenol A (TCBPA) is used as flame retardant, and it has been widely detected in the environmental and human samples. TCBPA is an endocrine disrupting chemical, but its effects on the immune system remains poorly understood. Here the effects of TCBPA on immune system were studied using combined in vivo and in vitro assays. Results showed that TCBPA could suppress the immune response in BALB/c mice via reducing the ratio of CD3 + T lymphocytes to regulatory T cells. Moreover, TCBPA exposure significantly induced the increasing secretion of four pro-inflammatory cytokines (IL-2, IL-12, IFN-γ, and TNF-α) and four anti-inflammatory cytokines (IL-4, IL-5, IL-10, GM-CSF) in mice serum. Interestingly, uterine edema was observed in over 80% TCBPA-treated mice after 14- day exposure. TCBPA was detected in 18.6% serum samples of 150 female volunteers in this study. Therefore, our findings provided evidence that TCBPA exposure may cause adverse outcomes on immune system and uterus, suggesting that environmental exposure of TCBPA, as well as its adverse effects on human health should be of concern.
研究领域:
免疫学
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环境科学
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生殖健康
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DOI
PubMed
高影响因子
CHEMOSPHERE
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2022
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IF 8.943
Yunjiang Yu,Xin Hua,Haibo Chen,Yue Yang,Yao Dang,Mingdeng Xiang
Tetrachlorobisphenol A (TCBPA), an alternative to tetrabromobisphenol A (TBBPA), is ubiquitous in the environment and could potentially impact the reproductive system of organisms. However, the mechanisms underlying TCBPA-mediated reproductive effects remain unclear. Herein, we exposed Caenorhabditis elegans ( C. elegans , L4 larvae) to TCBPA at environmentally relevant doses (0–100 μg/L) for 24 h. Exposure to TCBPA at concentrations of 1–100 μg/L impaired fertility of C. elegans , as indicated by brood size . After staining, the number of germline cells decreased in a dose-dependent manner, whereas germline cell corpses increased in exposed nematodes (10–100 μg/L TCBPA). Moreover, the expression of genes related to the germline apoptosis pathway was regulated following exposure to 100 μg/L TCBPA, indicating the potential role of DNA damage in TCBPA-induced apoptosis. Apoptosis was nearly abolished in ced-4 and ced-3 mutants and blocked in hus-1 , egl-1 , cep-1 , and ced-9 mutants. Numerous foci were detected in TCBPA (100 μg/L)-exposed hus-1::GFP strains. These results indicate that TCBPA induces hus-1 -mediated DNA damage and further causes apoptosis via a cep-1 -dependent pathway. Our data provide evidence that TCBPA causes reproductive toxicity via DNA damage-induced apoptosis.
研究领域:
环境科学
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毒理学
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分子生物学
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DOI
PubMed
高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2025
·Vol. 39
·期 3
·e70008
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IF 0
Yawen Wu,Xueying Hou,Ao Li,Ruijian Li,Qingqing Yang,Shaohua Jiang,Jing yu Hu,Qingliang You,Rui Guo
As the amount of tetrachlorobisphenol A (TCBPA) that causes potential adverse effects on human health in the environment is continually increasing. It is therefore important to develop new materials for the adsorption or degradation of these compounds using various techniques. In this study, two novel magnetic recyclable composite catalysts Zr–NiFe 2 O 4 @ZIF-67 and Zr–NiFe 2 O 4 @ZIF-8 were synthesized. These catalysts degraded tetrachlorobisphenol A (TCBPA) in water by activating peroxydisulfate (PDS)/peroxymonosulfate (PMS), respectively. The results show that the Zr–NiFe 2 O 4 @ZIF-67-5%/LED/(NH 4 ) 2 S 2 O 8 system can degrade 95% of TCBPA (20 mg/L) within 30 min, whereas the Zr–NiFe 2 O 4 @ZIF-8-10%/LED/KHSO 5 system degrades 90% of TCBPA within 30 min. In instances of metal leaching at low concentrations, nickel and iron ions declined to 0.008 mg·L −1 , TCBPA exhibits highly efficient and sustainable catalytic properties, maintaining over 80% efficacy across six cycles. The online infrared test experiment results showed the major functional groups disappearing within approximately 130 s. The results of electron paramagnetic resonance and free-radical-quenching experiments showed that SO 4 ˙ − , ˙OH, 1 O 2 , and O 2 ˙ − were involved in the degradation of TCBPA. The possible degradation paths are isomerization polymerization, dechlorination, hydroxylation, ring-opening by oxidation, and further transformation into small molecules of acids, aldehydes, alcohols and other compounds. Thus, in this study, a reliable technique for the degradation of halogenated bisphenol compounds is developed. Overall, the photocatalytic degradation of organic pollutants in water utilizing polymetallic composites as catalysts represents an innovative approach to water treatment, demonstrating enhanced catalytic activity and recyclability, with promising prospects for significant advancements in both theoretical research and practical applications.
研究领域:
环境科学
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材料科学
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化学工程
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DOI
SCIENCE OF THE TOTAL ENVIRONMENT
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2023
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IF 9.8
Yu Han,Hongmei Yang,Zhiqun Liu,Chao Hu,Imane Lamine,Zhiquan Liu,Panpan Gao,Yanming Sui,Pei Zheng,Hangjun Zhang,Xiuying Jia
Tetrabromobisphenol A (TBBPA) and tetrachlorobisphenol A (TCBPA) have been widely used as flame retardants. However, their potential health risks to organisms have raised concerns, particularly for liver toxicity. Present study aimed to explore the toxic effects of TCBPA and TBBPA on black-spotted frogs ( Pelophylax nigromaculatus ) liver oxidative stress, autophagy, and lipid accumulation. After exposure to 0.001, 0.01, 0.1, and 1 mg/L TBBPA and TCBPA for 14 days, the content of cholesterol and triglyceride were significantly elevated. In addition, the malondialdehyde level rose greatly in dose dependent. However, the glutathione level declined in high TBBPA groups (0.01 and 0.1 mg/L). Furthermore, expressions of Beclin1 , Atg5 , and Atg7 were significantly increased, while p62 was markedly declined, respectively. Results obstained suggested that TBBPA and TCBPA exposure induced liver toxicity in black-spotted frog. This study provided insights into the toxicity mechanism of bisphenol flame retardants in amphibians and will aid in the ecological risk assessment of flame retardants.
研究领域:
环境毒理学
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水生生物学
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分子生物学
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DOI
PubMed
高影响因子
WATER AIR AND SOIL POLLUTION
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2017
·Vol. 228
·期 2
·1-14
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IF 1.702
Zhang Jing,Liu Shicheng,Li Lingling,Ren Yuan,Feng Chunhua,Wei Chaohai,Li Yipeng,Huang Zhili
Tetrachlorobisphenol A (TCBPA) is a widely used flame retardant and a potential endocrine disruptor. We estimated the role of the microbial community in degradation of TCBPA in river sediment from the vicinity of an E-waste processing facility. The effects of different anaerobic conditions on degradation efficiency of TCBPA were investigated, and differences in bacterial communities among these conditions were analyzed by 16S ribosomal RNA (rRNA) gene sequencing. The most effective dechlorination of TCBPA occurred under methanogenic conditions followed by electron donor-enhanced conditions and sulfate-reducing conditions with initial sulfate concentrations of 1, 10, and 20 mM. The extent of TCBPA removal under these conditions mentioned above was 65, 44, 43, 23, and 23%, respectively. 16S rRNA gene sequence analysis indicated that five dominant genera in the phylum Chloroflexi and another five species of Bacteroidetes , Chlorobi , and Firmicutes in these five systems were largely involved in TCBPA dechlorination. The initial sample had a total relative abundance of autochtonous potential dechlorinating bacteria of 12%. After 160 days, these values increased to 29–43% under above conditions. Addition of TCBPA decreased bacterial diversity. Efficiency of TCBPA degradation depends on the abundance and metabolism of dechlorinating bacterial guilds. The effectiveness of dechlorinating microbes in degradation of TCBPA was reduced by high sulfate concentrations.
研究领域:
环境微生物学
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生物修复
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生态毒理学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2021
·Vol. 138
·期 44
·51315
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IF 3.125
Bowen Xu,Feilong Han,Xuqiang Pei,Xin Liu,Junying Zhang,Jue Cheng,Jingbo Zhao
Increasing the molecular weight of polyurethanes (PU) is an effective way to improve its mechanical properties, while, it is at the expense of sacrificing processability. Congruent modification in both mechanical and processing performances is still a challenge. Here, bis-phenol-A (BPA) derivatives, including tetrachlorobisphenol-A and tetrabromobisphenol-A, were chosen as the extender to synthesize thermoplastic PUs (TPU) containing blocked isocyanate units. This blocked isocyanate has a temperature-responsive reversible reaction due to phenol urethane bonds, so as to ensure the good mechanical properties at the service temperature and better processing performance via deblocking into smaller molecular weight at the processing temperature; in addition, negative induction effect of the halogen substituents endow BPA derivatives with deblocking reaction at lower temperature. The experimental results confirmed that the blocking reaction carried out completely at 70°C, and accompanying by the dramatical increase of molecular weight. The obvious deblocking reaction happened at 140°C, where the average molecular weight of TPUs decreased from 22,600 g/mol to 13,690 g/mol. Meanwhile, the melt flow index increased significantly with the extension of heating time, indicating that the PU has good processing properties. After the deblocking and re-blocking reactions were repeated alternatively, there is almost no change in its tensile properties, molecular weight and melt outflow index within two cycles under air atmosphere. This article proposes a strategy of congruent modification in both mechanical and processing performances of TPU.
研究领域:
材料科学
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聚合物化学
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化学工程
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DOI
高影响因子
THERMOCHIMICA ACTA
·
2019
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IF 2.251
Pengbo Zhang,Sayyed Asim Ali Shah,Feng Gao,Hao Sun,Zhichao Cui,Jue Cheng,Junying Zhang
As a representative single component epoxy resin, diglycidyl ether of bisphenol A resin (DGEBA) is the most widely used matrix in adhesives. However, challenges are still remained including high curing temperature and short shelf life. Herein, bisphenol A (BPA), Tetrachlorobisphenol A (TCBPA), and Tetrabromobisphenol A (TBBPA) as latent curing agents and imidazole as accelerator were used in adhesives. Curing kinetics was studied by non-isothermal DSC, using a model-fitting Málek approach and a model-free advanced isoconversional method of Vyazovkin. Results indicated that curing temperature of EP-BPA, EP-TCBPA, and EP-TBBPA was reduced to 126 ℃, 94 ℃, and 106 ℃, respectively. Storage stability evaluated by DSC indicated the shelf life was up to five months. After curing, molecular weights of the as-prepared linear polymers (EP-BPA, EP-TCBPA, and EP-TBBPA) were 33,822 g/mol, 14,913 g/mol, and 18,846 g/mol, and their tensile strength and shear strength were more than 40.06 MPa and 13.64 MPa, respectively.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
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2023
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IF 4.3
Lei Shi,Bingru Zhang,Yingfen Ying,Yunbing Tang,Shaowei Wang,Yang Zhu,Huitao Li,Ren-shan Ge,Yi Liu
Some halogenated bisphenol A (BPA) derivatives (tetrabromobisphenol A, TBBPA, and tetrachlorobisphenol A, TCBPA) are produced in a high volume and exist in PM 2.5 after waste burning. 11β-Hydroxysteroid dehydrogenase 2 (11β-HSD2) is a critical enzyme for placental function. However, whether halogenated bisphenols inhibit 11β-HSD2 and the mode of action remains unclear. The objective of this study was to investigate BPA derivatives on human and rat placental 11β-HSD2. The inhibitory strength on human 11β-HSD2 was TBBPA (IC 50 , 0.665 μM)>TCBPA (2.22 μM)>trichloro BPA (TrCBPA, 19.87 μM)>tetrabromobisphenol S (TBBPS, 36.76 μM)>monochloro BPA (MCBPA, 104.0 μM)>BPA (144.9 μM)>bisphenol S. All chemicals are mixed and competitive inhibitors . Rat 11β-HSD2 was less sensitive to BPA derivatives, with TBBPA (IC 50 , 96.63 μM)>TCBPA (99.69 μM)>TrCBPA (104.1 μM)>BPA (117.1 μM)>others. Docking analysis showed that BPA derivatives bind steroid active sites. Structure-activity relationship revealed that halogen atoms and LogP were inversely correlated with inhibitory strength on human 11β-HSD2, while LogS and polar desolvation energy were positively correlated with the inhibitory strength. In conclusion, halogenated BPA derivatives are mostly potent inhibitors on human 11β-HSD2 and there is structure-dependent inhibition.
研究领域:
环境科学
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药理学
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毒理学
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生物化学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）