ACS Applied Materials & Interfaces
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2021
·
IF 9.229
Yanfang Shen,Jiannan Pan,Xinyue Hu,Hui-Min Wen,John Q. Xiao,Jun Hu
Nanowire arrays can be conveniently fabricated by electrodeposition methods using porous anodized alumina oxide templates. They have found applications in numerous fields. Nanotube arrays, with their hollow structure and much enhanced surface-to-volume ratio, as well as an additional tuning parameter in tube wall thickness, promise additional functions compared with nanowire arrays. Using a similar fabrication method, we have developed a facile and general method to fabricate metallic nanotubes (NTs). Using Ni NTs as a model system, the mechanism of the hydrogen-assisted NT growth was postulated and confirmed by controlling the hydrogen formation with conductive salts in an electrodeposition solution, which improves the H2 concentration but prevents the large H2 bubbles from blocking the nanochannel of a template. The controlled hydrogen generation forces the growth along the wall of nanochannels in the templates, leading to the NT formation. The magnetic properties can be controlled by the NT wall thickness, making these NTs useful for various applications.
研究领域:
材料科学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2019
·Vol. 26
·期 10
·6035-6047
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IF 3.917
Chen Jingwen,Hou Chujun,Zhang Yakang,Xu Song,Yao Chao,Zhou Man,Li Zhongyu
We present a novel and facile fabrication of wall-thickness controlled ZrTiO 4 nanotubes (ZTNTs) using bacterial cellulose (BC) as a template. Unique porous thin-walls and interconnected channels within ZTNTs contribute a lot to the enhanced photodegradation activity. The roles of the wall-thicknesses in physicochemical properties as well as photocatalytic activities were careful investigated which might extend the synthesis of other nanotubes with higher catalytic performance.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 2
·283
·
IF 5.3
Yong Zhou,Guan Wang,Jiahao Wu,Zihao Chen,Chen Zhang,Ping Li,Yong Zhou,Wei Huang
Ternary orthovanadate compounds have received increasing attention due to their broad light absorption and diverse crystal structure. However, their multi-assembled crystal morphologies are limited mainly due to their initially polyatomic VO4groups. In this study, multi-prismatic hollow cubic CeVO4microstructures were fabricated by a one-step solvothermal method without any organic agents. The increase in wall thickness is in accordance with the radial direction of the quadrangular prism. Moreover, the overdose of the V precursor is favorable for the formation of hollow micro-cubic CeVO4, and the wall thickness changes from 200 to 700 nm. Furthermore, these CeVO4microstructures were applied to photocatalytic CO2reduction with a maximum CO generation rate of up to 78.12 μmol g−1h−1under visible light irradiation, which was several times higher than that of the other samples. This superior photocatalytic activity might be attributed to its good crystallinity and unique exposed interior structure. This study provides guidelines for the multi-assembled structure fabrication of ternary compounds and expands upon the exploration of the spatial structure of multivariate compounds.
研究领域:
材料科学
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化学
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环境科学
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DOI
高影响因子
ELECTROCHIMICA ACTA
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2019
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IF 5.383
Jian Cheng,Xiangxin Zhang,Xiaofei Miao,Chengwei Chen,Yongchuan Liu,Yuanqiang Chen,Junhong Lin,Sujing Chen,Wei Wang,Yining Zhang
We report a facile synthetic method to produce the interconnected hollow carbon spheres with various wall-thickness (as low as 9 nm). Instead of synthesizing and dispersing the silica hard templates in advance, we produce the templates in-situ to form the interconnected hollow-sphere structure. This interconnected structure provides a fast and efficient pathway for electron transfer . Meanwhile, decreasing the wall-thickness effectively shortens the distance of ion diffusion, which further promotes the high-rate performances of the interconnected hollow carbon spheres. For supercapacitor applications, at 1 A g −1 , the MF-1.1-20 (with 9-nm wall-thickness) electrode demonstrates a high specific capacitance of 208 F g −1 and retains 93% of its initial capacity after 10000 cycles. Under a large current density of 20 A g −1 , MF-1.1-20's specific capacity remains 153 F g −1 , demonstrating excellent high-rate performances. In another aspect, as the electrode for lithium-sulfur battery, MF-1.1-20/S composite electrode demonstrates high specific capacity of 996 mAh g −1 and 465 mAh g −1 at 0.2C and 10C, respectively. The excellent electrochemical behavior of the interconnected hollow carbon spheres demonstrates their potential for applications in high-rate energy storage devices.
研究领域:
材料科学
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电化学
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纳米能源
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储能技术
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碳材料
✓ 已验证
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2019
·
IF 4.191
Fuquan Xiong,Hang Wang,Han Xu,Yan Qing,Zhiping Wu,Yiqiang Wu
The fabrication of nanospheres with tailored structure has attracted much attention in material applications. Herein we found that the food additive, butylated hydroxytoluene (BHT), was able to adjust the solid and hollow structure of lignin nanospheres. At BHT concentrations greater than 0.3 mg/mL in tetrahydrofuran (THF), the obtained lignin nanospheres displayed a hollow structure due to phase separation between THF and water caused by BHT molecules, while the lignin nanospheres obtained without adding BHT exhibited a solid structure. BHT and lignin molecules containing a high content of the carboxy group did not participate in the formation of the nanospheres. Increases in the water stirring and dropping speeds reduced the diameter of the nanospheres, while increasing the initial concentration of lignin and BHT resulted in an increase in nanospheres diameters. Moreover, the shell wall thickness and single hole size could be controlled by employing the concentration of BHT and lignin. This work provides novel insights into the preparation of lignin nanospheres with tunable structures.
研究领域:
材料科学
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纳米技术
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化学工程
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2024
·
IF 5.3
Zishuo Zhou,Yaxue Liu,Pei Xie,Zongning Yin
Atherosclerosis is a chronic multifactorial cardiovascular disease. To combat atherosclerosis effectively, it is necessary to develop precision and targeted therapy in the early stages of plaque formation. In this study, a simvastatin (SV)-containing prodrug micelle SPCPV was developed by incorporating a peroxalate ester bond (PO). SPCPV could specifically target VCAM-1 overexpressed at atherosclerotic lesions. SPCPV contains a carrier (CP) composed of cyclodextrin (CD) and polyethylene glycol (PEG). At the lesions, CP and SV exerted multifaceted anti-atherosclerotic effects. In vitro studies demonstrated that intracellular reactive oxygen species (ROS) could induce the release of SV from SPCPV. The uptake of SPCPV was higher in inflammatory cells than in normal cells. Furthermore, in vitro experiments showed that SPCPV effectively reduced ROS levels, possessed anti-inflammatory properties, inhibited foam cell formation, and promoted cholesterol efflux. In vivo studies using atherosclerotic rats showed that SPCPV reduced the thickness of the vascular wall and low-density lipoprotein (LDL). This study developed a drug delivery strategy that could target atherosclerotic plaques and treat atherosclerosis by integrating the carrier with SV. The findings demonstrated that SPCPV possessed high stability and safety and had great therapeutic potential for treating early-stage atherosclerosis.
研究领域:
药理学
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心血管疾病
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药物递送系统
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纳米技术
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产品关联
DOI
PubMed
高影响因子
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
·
2024
·Vol. 51
·期 4
·e13845
·
IF 2.4
Wen-Cong Gao,Tie-Hua Yang,Bin-Bao Wang,Qian Liu,Qing Li,Xiao-Huan Zhou,Chang-Bo Zheng,Peng Chen
Abnormalities in vascular smooth muscle cells (VSMCs) are pivotal in the pathogenesis of cardiovascular pathologies such as atherosclerosis and hypertension. Scutellarin (Scu), a flavonoid derived from marigold flowers, exhibits a spectrum of biological activities including anti-inflammatory, antioxidant, antitumor, immunomodulatory and antimicrobial effects. Notably, Scu has demonstrated the capacity to mitigate vascular endothelial damage and prevent atherosclerosis via its antioxidative properties. Nevertheless, the influence of Scu on the formation of VSMC-derived foam cells remains underexplored. In this study, Scu was evidenced to efficaciously attenuate oleic acid (OA)-induced lipid accumulation and the upregulation of adipose differentiation-associated protein Plin2 in a dose- and time-responsive manner. We elucidated that Scu effectively diminishes OA-provoked VSMC foam cell formation. Further, it was established that Scu pretreatment augments the protein expression of LC3B-II and the mRNA levels of Map1lc3b and Becn1, concurrently diminishing the protein levels of the NLRP3 inflammasome compared to the OA group. Activation of autophagy through rapamycin attenuated NLRP3 inflammasome protein expression, intracellular lipid droplet content and Plin2 mRNA levels. Scu also counteracted the OA-induced decrement of LC3B-II levels in the presence of bafilomycin-a1, facilitating the genesis of autophagosomes and autolysosomes. Complementarily, in vivo experiments revealed that Scu administration substantially reduced arterial wall thickness, vessel wall cross-sectional area, wall-to-lumen ratio and serum total cholesterol levels in comparison to the high-fat diet model group. Collectively, our findings suggest that Scu attenuates OA-induced VSMC foam cell formation through the induction of autophagy and the suppression of NLRP3 inflammasome activation.
研究领域:
心血管疾病
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药理学
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细胞生物学
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炎症
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Xiaopei Li,Peng Lu,Zhaoyang Liu,Ziang Wen,Xiangyu Li,Chufan Wang,Wanjun Jin,Bin Zhou,Ningping Huang,Meijuan Song,Xiaowei Wang
Effective therapies for myocardial infarction (MI) are essential in lowering associated mortality rates. While hydrogel-based patch therapy has shown promise in improving post-MI cardiac function; it falls short in terms of mature stimulation and lacks the necessary combination of conductive, mechanical, and anisotropic cues for optimal efficacy. In this study, we developed an anisotropic hydrogel by incorporating polydopamine-reduced graphene oxide-ferric oxide (PDA-rGO-Fe 3 O 4 ) nanohybrids into gelatin methacrylate (GelMA) hydrogels under a direct current-driven magnetic field. Cardiomyocytes (CMs) cultured on anisotropic hydrogels demonstrated oriented growth and exhibited symmetrical contraction-relaxation behaviors, surpassing the performance of cells cultured on pure GelMA and isotropic ones. Moreover, both external electrical and alternating magnetic field stimulations enhanced sarcomere functionality, gap junction protein expression, and electrophysiological activities in CMs within the anisotropic hydrogel group. In an acute MI rat model, the application of the anisotropic hydrogel patch significantly improved cardiac function, mitigated adverse left ventricular (LV) dilation and remodeling, reduced infarct size, increased LV wall thickness, promoted angiomyogenesis, and preserved the structural and connected features between CMs. Overall, our findings highlight the potential of electromagnetic, conductive, and anisotropic GelMA-based hydrogels as scaffolds for mimicking the natural functional myocardium layer and developing effective cardiac patches.
研究领域:
心血管工程
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生物材料科学
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组织工程
·
再生医学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）