ULTRASONICS SONOCHEMISTRY
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2017
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IF 4.218
Xiaoming Luo,Juhang Cao,Jing Ren,Haipeng Yan,Limin He
The suspension characteristics of water droplet in oil were investigated under ultrasonic standing waves with high-speed photography in this paper. Firstly, the suspension position of droplet was predicted by theoretical derivation. The motion trajectory of droplet was captured and a kinetic analysis was applied to characterize the suspension position of droplet. The effects of droplet size, acoustic pressure, frequency, as well as density ratio of water and oil on the suspension position of droplet were analyzed in details. It was proved that the droplet size had little effect on the suspension position at different frequencies. The suspension zone approached minimum at 39.4 kHz, and the suspension position of droplet was insensitive to acoustic pressure amplitude and density ratio at this frequency. These would be advantageous to maintain the stability of droplet banding and shorten the width of banding. In addition, it was proved that the suspension position of droplet is approximately linear with the density ratio at different frequencies.
研究领域:
物理学
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化学工程
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声学
✓ 已验证
DOI
高影响因子
CARBON
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2025
·
IF 11.6
Xinyan Huang,Qingchen Bai,Jian Jiang,Fengyu Qu,Huiming Lin
With various physiological effects, nitric oxide (NO) holds significant promise in anticancer. Because their functions are concentration-dependent, the controllable NO supplement and high release capacity are vital to realize the multifaceted capabilities. Here, C 3 N 4 nanosheet was prepared as new NO donor, revealing the specific release profile to tumor microenvironment (TME, weak acidity and high expressed H 2 O 2 ). The NO release is initiated with the protonation of N (high electronegativity) and the subsequent oxidation of active -NH x species. Unlike the organic NO donors, inorganic C 3 N 4 nanosheets don’t need extra carriers, which is associated with high N atom ratio to grant the great release capacity. Furthermore, the as-synthesized C 3 N 4 nanosheet exhibits piezoelectric feature, enabling reactive oxygen species (ROS) generation under ultrasound (US) treatment for sonopiezoelectric therapy (SPT). The sufficient ROS allows for the amplification of NO release triggered by US. The intracellular NO bubbles also enhance the contrast for ultrasonic imaging, guarantying real-time monitoring of the therapeutic effect. Additionally, NO can capture ROS in situ to generate peroxynitrite anion (·ONOO - ) with stronger oxidability to damage mitochondria and DNA seriously. Without US, C 3 N 4 nanosheet still can produce the moderate amount of NO triggered by TME to downregulate immune checkpoints (PD-L1), normalize vascular, and relieve hypoxia, all of which contributes to the overall anticancer efficacy. The synergic therapy (NO+SPT) also could enhance immunogenic cell death (ICD), thereby stimulating anticancer immune response for the inhibition of metastasis and recurrence, efficiently.
研究领域:
生物医学工程
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癌症治疗
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED MATERIALS
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2025
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IF 26.8
Guangru Li,Xinyue Dai,Yuling Liu,Jinli Chen,Weijie Yu,Ping Li,Luodan Yu,Yu Chen
Recombination of sono-generated charge carriers is a major barrier hindering the effectiveness of piezocatalytic oncotherapy. Herein, ultrathin oxygen vacancy-engineered self-heterojunction bismuth oxysilicate (O v -BOS) nanosheets with alternating hetero-layered nanostructure are constructed for enhanced sono-piezocatalytic tumor therapy. Benefiting from its out-of-plane asymmetry, O v -BOS features an exceptional electromechanical strain coefficient (d * 33 = 203 pm/V), highlighting its outstanding capability as a piezoelectric heterojunction for energy conversion. Particularly, the oxygen vacancy engineering facilitates the spatial redistribution of bands across the alternating [Bi 2 O 2 ] and [SiO 3 ] layers in O v -BOS, promoting effective charge separation and stratified charge storage, thereby further suppressing recombination of sono-generated charge carriers in a manner analogous to heterojunctions. Leveraging this strategy, O v -BOS demonstrates efficient reactive oxygen species production and exhibits superior peroxidase and catalase-like activities compared to the conventional piezoelectric nanocatalysts. Consequently, the enhanced radical generation induced the specific cancer-cell pyroptosis via caspase-3 mediated gasdermin E-dependent pathway. Therefore, the engineered interlayer self-heterojunction provides an efficient strategy for the design and engineering of high-performance piezoelectric nanocatalysts.
研究领域:
纳米技术
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材料科学
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生物医学工程
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肿瘤学
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物理化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Xiao Guan,Tianjun Lan,Dazhe Zhao,Zhe Liu,Kaijun Zhang,Yexi Zhou,Yu Zhao,Yucong Pi,Chengyue Lu,Hanran Yu,Rongyao Pan,Haipeng Xia,Bingpu Zhou,Junwen Zhong
Textiles with inherently porous architectures are commonly employed for acoustic absorption. Although recent advances in textile-based audio interfaces have enabled sound emission, they lack robustness under unstructured conditions. Therefore, this study introduces a strategy that integrates textile structures with a durable actuation mechanism to overcome these limitations. Through optimized theoretical modeling, this study enhances the vibration amplitudes, effectively compensating for the intrinsic acoustic damping losses of textiles, achieving a relatively high and flat sound pressure level of 71.7 ± 3.3 dB. Notably, the audio interface maintains stable performance under various mechanical deformations, including stretching, compression, bending, and twisting. Furthermore, this audio interface preserves the essential characteristics of textiles, such as washability and breathability, and remains fully functional even in extremely humid conditions, such as heavy perspiration. The versatility of this approach is demonstrated through three practical applications: sound-beanie, talking-cloth, and sound-sofa. In each case, this audio interface delivers high-quality acoustic performance and robustness to unstructured conditions. The proposed strategy is anticipated to enhance the design of wearable audio interfaces for real-world applications.
研究领域:
材料科学
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声学
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可穿戴技术
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智能纺织品
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机电系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）