DYES AND PIGMENTS
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2019
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IF 4.018
Ke Cheng,Rui Qi,Shuai Lan,Hongyang Wang,Xuefang Zheng,Chun Liu,Dandan Jia,Lei Cao,Dongjun Wang
A novel concept of anti-counterfeiting is proposed, based on the special properties of excitation-dependent-fluorescence (EDF) and emission-dependent-excitation (EDE) of carbon dots (CDs) in polymer matrix . EDF and EDE behaviors can be controlled by adjusting the concentration of CDs or changing species of CDs and their corresponding polymer matrix. Meanwhile, multi-emission in EDF spectrum is observed, which is helpful to identification. Particularly, the curves in EDF or EDE spectrum as unique and sophisticated as human fingerprints are highly difficult to replicate, which promise practical applications of CDs in the field of anti-counterfeiting.
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高影响因子
Materials Today Nano
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2024
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IF 8.2
Jiangyong Li,Qin Li,Qian Yang,Qi Tang,Xiaoyi Hu,Qing Liu,Liangke Zhang
Reactive oxygen species (ROS)-based antitumor strategies, particularly chemodynamic therapy, have garnered considerable attention. However, challenges such as difficulties in achieving deep penetration, relatively low H 2 O 2 levels in the tumor microenvironment, the requirement for low pH by the Fenton reaction, and their short lifespan have impeded satisfactory therapeutic outcomes. Hence, we have developed a nanoplatform with enhanced permeability that not only generates significant amounts of ROS but also converts them into longer-lasting reactive nitrogen species (RNS), thereby improving tumor therapy efficacy. In our study, carbon dots were functionalized by doping with gold atoms and grafting nitrosoglutathione (GSNO) to form ACN, which exhibits glucose oxidase-like properties and enables laser-responsive NO release. ACN and indocyanine green (ICG) were then loaded onto MnO 2 nanoflowers to form MnO 2 @AI. Upon arrival at the tumor site, MnO 2 reacts with H 2 O 2 and GSH, leading to its degradation and the subsequent release of ACN, which is characterized by three permeation-promoting properties: ultra-small size, positive charge, and NO content. In addition, ACN promotes H 2 O 2 production through glucose metabolism and reduces pH, both of which enhance the Fenton-like reaction of MnO 2 , thereby amplifying ROS generation. The ICG in MnO 2 @AI enhances its photothermal properties, leading to the responsive release of NO from GSNO grafted onto ACN, which then reacts with the increased ROS to generate more toxic RNS. Collectively, the approach described herein offers substantial potential for advancing the treatment of malignant tumors.
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高影响因子
POLYMER
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2016
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IF 3.586
Qian He,Yali Yuan,Fengxia Chen,Zhi Ma,Xingqi Zhu,Rui Song
In this work, we systematically investigated the aggregation and confined crystallization behavior of polymethylene- b -poly acrylic acid diblock copolymers (PM- b -PAA, M 93 A 94 ) under the influence of polyethyene polyamine (PPA). With the increasing molar ratio of PPA, the morphologies of PM- b -PAA micelles experienced sphere-to-band-to-sheet transformations with regular changes of sizes on cooling from 80 °C mixed solution. Further investigation of the crystalline feature of PM- b -PAA indicated that the crystallization of PM block was profoundly restrained by PPA with the dual confinements, i.e., chemical and physical confinement which exerted through the hierarchical hydrogen bonding and 3D hydrogel network, respectively, in the mixed system. In particular, when the PPA and PM- b -PAA aqueous solution were mixed with equivalent volume, hydrogels was accessible. And rheology property indicated that the BCP/PPA-0.5 hydrogels hold the maximal storage modulus G′, and meanwhile the minimum loss tangent, tanδ.
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高影响因子
CHEMOSPHERE
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2024
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IF 8.1
Hao Sun,Xiaobing Li
In the alkaline-surfactant-polymer flooding emulsion, oil droplets with various sizes exhibited different interfacial properties , resulting in different stabilization and destabilization behaviors. In view of this, it is expected to achieve outstanding oil-water separation efficiency by screening targeted demulsifier for oil droplets with different size ranges (0–1, 1–5 and 5–10 μm). Based on the size effect of oil droplets, a series of multibranched polyether-polyquaternium demulsifiers that integrated different charge neutralization and interfacial displacement functionalities were designed by regulating the cationicity and EO:PO ratios. As a result, the most effective polyether-polyquaternium variant for each size range of oil droplet was screened out. By employing these three selected polyether-polyquaternium variants in a sequential batch demulsification test, the maximum demulsification efficiency of 95.1% was obtained, which was much higher than that using a single polyether-polyquaternium variant (82.5%, 80.5% and 83.8%). The adsorption behaviors of polyether-polyquaternium variants on the oil/water interface were investigated by the molecular dynamics simulation. Moreover, the interfacial properties and oil droplet size variations during the demulsification process were monitored, so as explore the demulsification mechanism. This demulsification protocol based on the size effect of oil droplets with its excellent oil-water separation performance offered significant technical promise for the emulsified oil wastewater disposal.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Sheng Zhao,Feng Feng,Yuanting Chen,Xiaoyang Huang,Zhenzhen Wang,Chenfang Miao,Shaohuang Weng,Mingrui Lin
Minocycline (MC), a widely used broad-spectrum antibiotic in both clinical practice and the food industry, exhibits remarkable efficacy alongside notable adverse effects. Consequently, the development of a straightforward yet efficient detection strategy for MC in medical science and food industry assumes paramount importance to avoid its misuse and accumulation. Herein, fluorine-doped carbon dots (F-CDs) with favorable optical properties were designed and synthesized via a hydrothermal procedure using tetrafluorophthalic acid and polyethylene polyamine as raw materials. It was observed that MC quenched the fluorescence of F-CDs through the mechanism of static quenching and inner filter effects. When the concentrations of MC (C MC ) were in the range of 0.5–25 μg/mL, there was a good linear relationship between C MC and the fluorescence quenching efficiency (QE, calculated as (F 0 F)/F 0 ) with the equation of Y = 0.025*C MC + 0.012 and the detection limit of 0.24 μg/mL ( n = 8). Furthermore, this method demonstrated high sensitivity, simplicity, and rapidity in determining the percentage label content of minocycline hydrochloride capsules, as well as the recovery of MC in human serum samples and dairy products. The excellent analytical performance of this method underscores its promising potential for drug concentration monitoring, clinical blood drug concentration assessments, and food safety control. The findings highlight the importance and potential of this strategy in ensuring strict quality control of MC in various applications.
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高影响因子
危险品化学品经营许可证（带存储）