Materials
·
2023
·Vol. 16
·期 15
·5206
·
IF 3.4
Guijun Yang,Houjiang Liu,Ang Li,Tiansheng Liu,Qiqin Lu,Fang He
Titanium alloy Ti6Al4V is a commonly used bone implant material, primarily prepared as a porous material to better match the elastic modulus of human bone. However, titanium alloy is biologically inert and does not have antibacterial properties. At the same time, the porous structure with a large specific surface area also increases the risk of infection, leading to surgical failure. In this paper, we prepared three porous samples with different porosities of 60%, 75%, and 85%, respectively (for short, 3D-60, 3D-75, and 3D-85) using 3D printing technology and clarified the mechanical properties. Through tensile experiments, when the porosity was 60%, the compressive modulus was within the elastic modulus of human bone. Anodic oxidation technology carried out the surface modification of a 3D-printed porous titanium alloy with 60% porosity. Through change, the different voltages and times on the TiO2oxide layer on the 3D-printed porous titanium alloy are different, and it reveals the growth mechanism of the TiO2oxide layer on a 3D-printed unique titanium alloy. The surface hydrophilic and antibacterial properties of 3D-printed porous titanium alloy were significantly improved after modification by anodic oxidation.Keywords:Ti6Al4V porous titanium alloy;3D printing;anodic oxidation;antibacterial
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
VACUUM
·
2018
·
IF 2.067
Guobo Yang,Baoqiang Xu,Xianjun Lei,Heli Wan,Bin Yang,Dachun Liu,Zhijun Wang
A new process to fabricate porous titanium by calcium vapor in-situ reduction of titanium sespuioxide was presented in this paper. The mixture of Ti 2 O 3 and CaCl 2 powders was preformed and reduced by calcium vapor. The porous titanium structure was obtained after leaching reduction products with hydrochloric acid and deionized water. The pore structure , morphology, composition of reduction products were investigated by SEM-EDS and XRD . The influence of different contents of anhydrous calcium chloride on porosity was discussed. The results show metallic titanium products with two types of pore structures and vacuum sintering treatment strengthened effectively connection between titanium particles. The porosity of porous titanium samples was 62%–82% and more than 90% of pores are open-pores.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2020
·
IF 5.289
Zhijun Wang,Baoqiang Xu,Jia Yang,Bin Yang,Heng Xiong,Guobo Yang,Fengkang Wang
A route is present for preparing porous titanium scaffolds with open and interconnected pore morphology through calcium thermal in-situ reduction of TiO precursor. Titanium and dioxide titanium powders, with ammonium carbonate as the space holder, were used to prepare porous precursor whose main phase is TiO by a sintering process. Then calcium vapor was conduced to reduce the precursor and CaO was removed by leaching to obtain porous titanium structures. The morphology, pore structure, phase analysis of porous titanium precursor and porous titanium scaffolds were investigated by means of XRD, SEM and EDS. The porosity was observed by Archimedes method. By this route, the porous titanium with multi-gradient pore sizes ranging from a few microns to several hundred microns was formed. The porous titanium is of multi-gradient pore size distribution of 100 μm bigger, 10 μm∼100 μm and 10 μm smaller. The micro-pores on the pore walls increases connectivity between the macro-pores throughout the porous titanium interior. The porous titanium obtained by this method has a porosity of 50–65% and a titanium content more than 99%.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS & DESIGN
·
2016
·
IF 3.997
Qiuyan Li,Guo He
Porous titanium with entangled wire structure was enhanced by filling gelatin into the porous structure to form a titanium-gelatin (Ti-G) composite. The density of the composites was 1.6–2.5 g/cm 3 , similar to that of bone. The strength and elastic modulus of the composites reached 12.9–39.4 MPa and 2.5–7.4 GPa, respectively, which were comparable to that of the cortical bone. Gelatin in Ti-G composite acted as the carrier of gentamicin sulphate (GS). Antibacterial efficacy of GS-loaded Ti-G against Staphylococcus aureus strain was tested. The lack of growth of Staphylococcus aureus strains was found in Luria–Bertani (LB) medium containing GS-loaded Ti-G. GS release behavior from the GS-loaded Ti-G composites in phosphate buffer saline (PBS) was investigated. The effective GS release times from Ti30-G and Ti50-G were 120 h and 168 h, respectively. The gelatin in Ti-G was just degraded 3.2% at the immersion time of 168 h and 9.0% at 336 h. The degradation rate of gelatin was much slower than release rate of GS, indicated that the GS release from gelatin was less affected by the gelatin degradation. These Ti-G composites loaded with drug(s) are expected to be good candidates as functional bone repair materials with drug-delivery capabilities.
研究领域:
生物材料学
·
医学工程
·
药剂学
✓ 已验证
产品关联
DOI
高影响因子
Metals
·
2022
·Vol. 12
·期 12
·2004
·
IF 2.695
Nan Lou,Bin Zhu,Lilin Luo,Yuqin Zhang,Zengdong Meng
Bioactivity and stress shielding are the most important problems of medical implanted porous titanium. In this study, porous titanium with 40% porosity was prepared by one-step spark plasma sintered (SPS) technology, and the surface of porous titanium was modified by a simplified alkali treatment method. The effects of a high concentration on pore properties, mechanical properties, and biological activities of porous titanium were investigated. The results show that the surface of porous titanium treated with a high concentration of alkali forms an interconnected network layer, which provides nucleation points for the formation of apatite. Porous titanium can still meet the requirements of hard tissue replacement after treatment with high-concentration alkali solution (yield strength (130 MPa) and elastic modulus (6.0 GPa)). A layer of apatite is formed on the surface of porous titanium after alkali treatment. The ability of inducing apatite formation increases with the increase of lye concentration. In addition, the results of proliferation and live dead cell staining of bone mesenchymal stem cells (BMSC) showed that alkali treatment had no toxic effect on the cells. With the increase of concentration, the cell activity was significantly enhanced. Therefore, the bioactive porous titanium modified with simplified alkali has a good medical prospect as artificial bone material.Keywords:porous titanium;alkali-treatment;network structure;mechanical properties;in vitro bioactivity
研究领域:
材料科学
·
生物医学工程
·
生物材料
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
Yufei Tang,Xuan Zhou,Qi Zhang,Lei Chen,Kang Zhao,Zixiang Wu
Directional lamellar porous titanium scaffolds are widely used as bone implant bearing materials because of their anisotropic pore structure . Their mechanical properties can be effectively improved by enhancing the strength of pore walls through the introduction of ceramics. In this work, porous titanium implants were prepared by freeze casting combined with TiH 2 decomposition. The graphene was introduced into the pore walls of porous titanium, which could transform into titanium carbide (TiC) in situ upon sintering. TiC was evenly distributed in the lamellar pore walls, and the interface was well bonded. The compression strength of the fabricated implants was up to 389.94 MPa when the graphene content was 3 wt%, which was 377.8% times as high as the porous titanium. The crack propagation was resisted by TiC because of the “pinning” effect on the pore wall. Some of TiC were pulled out from the matrix, and others were fractured. The strength of the fabricated implants was improved significantly by the large consumption of fracture energy. Also, fabricated porous titanium implants with TiC are suitable for bone implantation.
研究领域:
生物材料学
·
医学工程
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Yutang Kang,Shihui Jiao,Yue Zhao,Boran Wang,Zhenwei Zhang,Wen Yin,Yumei Tan,Guangsheng Pang
Both high permeability and high selectivity are advantageous for separation membrane materials. It is a huge challenge to fabricate a membrane that simultaneously possesses both high permeability and high rejection. Here, we fabricated a TiO 2 nanofibers ultrafiltration membrane by depositing hydrogen titanate nanofibers on a porous titanium substrate and sintering at 450 °C. The porous titanium supported TiO 2 nanofibers ultrafiltration membrane has a superhydrophilic separation layer and a high pure water flux of 940 L m −2 h −1 bar −1 . The average pore size of the TiO 2 nanofibers ultrafiltration membrane is 14 nm. The nanoparticles that particle size is smaller than pore size of TiO 2 nanofibers ultrafiltration membrane such as Bovine serum albumin (BSA, 11 nm) and 3 nm TiO 2 nanoparticles can be rejected with high permeation flux and high rejection efficiency. The obtained ultrafiltration membrane exhibits excellent antifouling property, the flux recovery ratio reaches to 97%. Also, the fouling of the TiO 2 nanofibers ultrafiltration membrane can be removed by heating treatment, the permeation flux of the membrane can be easily recovered.
研究领域:
材料科学
·
环境工程
·
膜技术
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED ENGINEERING MATERIALS
·
2020
·Vol. 22
·期 11
·2000519
·
IF 3.217
Chuan Zong Wu,Zhu Yin Chen,Xinli Liu,Ting Shen,LiGuo Zu,Lei Zhang
Porous titanium scaffolds with high porosity and connected macropores are fabricated by adding zirconium acetate to control the ice crystal growth during freeze casting. The influences of zirconium acetate additives on the phase composition, pore structure, and mechanical properties of porous titanium are studied. As modified by zirconium acetate, the X-ray diffraction peaks of titanium moves to a smaller angle, and the zirconium is evenly distributed on the titanium matrix. With the increase in the concentration of zirconium from 0 to 60 g L −1 , the pore morphology of porous titanium changes from typical lamellar to the honeycomb, the pore size distribution becomes wider. The average pore size and porosity increases from 44 ± 11 to 126 ± 35 μm and from 46.4 ± 1.3 to 59.1 ± 1.3%, respectively. As the concentration of zirconium acetate is 40 g L −1 , the porosity and the pore size of the porous titanium scaffolds are comparable with those modified by 10 g L −1 zirconium acetate, but the compressive strength is 2.3 times higher. Zirconium acetate as an additive has an excellent performance in optimizing the pore structure and mechanical properties of water-based freeze-cast porous titanium.
研究领域:
生物材料学
·
组织工程
·
金属材料科学
·
医用植入材料
·
多孔材料
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2019
·Vol. 34
·期 24
·4045-4055
·
IF 1.982
Bo-Qiong Li,Xin-Cheng Li,Xing Lu
In recent years, there has been a significant thrust toward the development of novel implant alloys based on β-Ti with low Young’s modulus to prevent stress shielding. In this study, porous Ti–Nb–Ta–Zr alloys with porosity of <55% and macro-pore size of 100–400 μm for biomedical applications were successfully fabricated by a space-holder method. The microstructure and compressive behavior were studied. The results show that the micro-pore size of porous Ti–Nb–Ta–Zr alloys decreases with an increase in the amount of the process control agent (PCA), which has no obvious effect on the porosity and the macro-pore size formed by the space holder. Porous Ti–Nb–Ta–Zr alloys fail mainly because of the cleavage and ductile fracture with some dimples in compression. The compressive modulus increases from 0.6 to 6.5 GPa with the increase in the PCA and decrease of the space holder. The influence mechanism has been analyzed by the finite element calculation and the Gibson–Ashby model.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Mao Zhou,Ruizhuo Ouyang,Yuhao Li,Yuqing Miao
3D microspheres from the in situ synthesis, growth and organization of Ni-Mo-S nanoparticles (NPs) on porous Ti plate were obtained through a typical hydrothermal method . The Ni-Mo-S/Ti electrode exhibited excellent electrocatalytic performance for hydrogen evolution reaction (HER) in strong acid electrolyte. HER occurs at the relatively low onset potential of −4 mV with high current of 10 mA/cm 2 at low overpotential of 30 mV in 0.5 M H 2 SO 4 . Furthermore, the Ni-Mo-S/Ti exhibited excellent electrocatalytic stability over an extended period of 60000 s without obvious current decrease observed. The multinary composition , 3D microsphere-like structure from nanoparticles, porous supporting substrate, the good conductivity of Ti and good electron transfer between electrode and catalysts, all of them are combined to contribute to the high HER electrocatalytic activity of the Ni-Mo-S/Ti. The good stability comes from the stability of catalysts and Ti themselves, and the tight contact between catalysts and supporting electrode.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2015
·
IF 2.729
Yapeng He,Yujie Dong,Weimin Huang,Xuqing Tang,Honghong Liu,Haibo Lin,Hongdong Li
The electrochemical oxidation of acetaminophen, a kind of potentially dangerous pharmaceutical compound, is conducted on planar and porous Ti/boron-doped diamond (BDD) electrodes to investigate the effect of electrode structure on the electrochemical oxidation behavior. Oxidative peak corresponding to the electron transfer of acetaminophen could be observed around 0.90 V (versus saturated calomel electrode, SCE) on BDD electrodes. The current response from a chronoamperometric curve is proportionally linear in the concentration range from 0 to 3 mmol L − 1 and higher response slope could be obtained on porous Ti/BDD electrode. Complete mineralization can be realized on Ti/BDD electrodes while porous Ti/BDD presents higher COD removal rate and current efficiency compared with planar BDD. The decay kinetics of acetaminophen on BDD electrodes follows a pseudo-first-order behavior, and the corresponding apparent rate constants are 0.208 and 0.344 h − 1 for planar and porous Ti/BDD electrodes at 30 mA cm − 2 . From the detection of hydroxyl radicals , higher generation rate and amount can be obtained on porous Ti/BDD electrode. The enhancement for electrochemical oxidation is related to the porous structure of porous Ti/BDD electrode, which provides more active sites for hydroxyl radicals ( OH) generation. The discrepancy between the COD removal and amount of OH could be explained by the utilization rate of OH.
研究领域:
环境科学
·
电化学
·
药物降解
✓ 已验证
产品关联
DOI
高影响因子
Journal of Energy Storage
·
2024
·
IF 8.9
Zhengdao Li,Hui Dai,Xingjian Zhang,Lu Ruan,Jiping Shi,Ting Li,Yong Zhou
Porous titanium nitride nanowires were fabricated on carbon fibers (CFs) by growing a TiO 2 nanowires array on CFs and subsequent ammonification (TiN-CF). This design combined the high electrical conductivity of CF with the superior electrocatalytic activity of TiN to construct a fast electron-transport passage and highly active sites along the electron pathway. Benefiting from both its construction advantages and high flexibility, TiN-CF could be effectively utilized in fiber-shaped dye-sensitized solar cells (FDSSCs) and fiber-shaped lithium-ion battery (FLIB). For the FDSSCs, TiN-CF had been demonstrated to function as low-cost and excellent counter electrodes (CEs) with a desirable photoelectric conversion efficiency of 6.48 %, comparable to or even surpassing that of a Pt wire CE at 6.36 %. When used as the anode for FLIB, TiN-CF exhibited favorable electrochemical properties including a good initial discharge capacity of 556.6 mAh g − 1 at rates of 0.2C, a high rate capability of 493.5 and 272.2 mAh g − 1 at 1C and 10C respectively, as well as superior cyclic stability with a capacity retention of 420.5 mAh g − 1 after 300 cycles at 2C. This work also provides valuable insights for future development and rational design in fiber-shaped electronic devices.
研究领域:
材料科学
·
能源技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）