Laser & Photonics Reviews
·
2024
·
IF 9.8
Jinming Hu,Shengting Zhu,Ying Lv,Ronghui Guo,Min Gu,Yinan Zhang
Holography, as a technique for coherent wavefront reconstruction, is extensively used in numerous optical applications such as optical imaging, 3D display, photolithography, and optical artificial intelligence. In order to achieve highly compact and functional integration with optoelectronic devices, the hologram needs to possess ultrathin thickness as well as multicolor functionality. However, its thickness is typically limited to optical wavelength ranges due to the requirement for pronounced amplitude or phase modulation, and it generally operates at a single wavelength band without wavelength-multiplexed channels. Here, the hologram is decreased thickness to sub-ten nanometers by exploiting the large refractive index and strong exciton absorption of 2D perovskites. Ultrathin perovskite holograms and holographic neural networks with high stability are successfully developed by using femtosecond laser direct writing, and their operation wavelength can be rationally tuned from 400–515 nm through halide anion engineering. Consequently, the wavelength can be multiplexed with low cross-talks by stacked perovskite nanolayers for applications of holographic display and neural networks without the usages of complex optical structures or filters. This work provides a feasible and promising technical route for integrating ultrathin, high pixel density, and multiplexed holographic structures with flat optoelectronic devices for next-generation integrated optical systems.
研究领域:
光学
·
材料科学
·
人工智能
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xingping Zhang,Bin Qiao,Yansong Li,Yu Zhou,Hualin Yang
Fluorene, a kind of polycyclic aromatic hydrocarbons (PAHs), was harmful to human health. In this work, a multi-wavelength and multicolor immunoassay was established for detecting fluorene based on the gold nanorods (AuNRs) growth. In the target recognition, fluorene was recognized by monoclonal antibody (McAb) through a competitive immune response. Then, the alkaline phosphatase-labeled Goat anti-Mouse IgG (ALP-IgG) as secondary antibody was used to combine with McAb. In signal output, ALP-IgG was used to catalyze 4-aminophenylphosphate to 4-aminophenol which can reduce Ag(I) to Ag(0). Then, the Ag(0) can deposit on the surface of AuNRs to cause the AuNRs growth. Along with the AuNRs growth, the absorption wavelength of the AuNRs was blue shifted and the color changed accordingly. The linear range of this immunoassay for fluorene was 0.063–4.000 ng/mL with the limit of detection (LOD) of 0.035 ng/mL. This immunoassay had excellent selectivity for fluorene according to the fact that it can distinguish fluorene among 16 PAHs. Meanwhile, this proposed immunoassay had a potential to detect fluorene in different water samples with satisfactory recovery rates (83 %–96 %).
研究领域:
分析化学
·
环境科学
·
生物技术
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Junmei Fan,Ruitao Zhu,Wei Han,Hongfei Han,Liping Ding
Flavonoids are a kind of natural polyphenols which are closely related to human health, and the identification of flavonoids with similar structures is an important but difficult issue. We herein easily constructed a powerful fluorescent sensor ensemble by using surfactant cetyltrimethylammoniumbromide (CTAB) encapsulating two commercially available fluorescent probes ( F1 and F2 ) with multi-wavelength emission. Fluorescence measurements illustrate the present sensor ensemble exhibits turn-off responses to flavones and flavonols but ratiometric responses to isoflavones, owing to different FRET processes. The heat map and linear discriminant analysis (LDA) results show that this single sensor can effectively distinguish 6 flavonoids belong to three subgroups by collecting the fluorescence variation at four typical wavelengths. Moreover, it can be applied to identify different flavonoids even in biofluids like serum and urine, providing potential practical application.
研究领域:
分析化学
·
生物医学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROSCOPY LETTERS
·
2017
·
IF 0.794
Hongliang Wang,Baohua Liu,Zhengguang Li,Lei Yang
Dye leakage and the nonlinear relationship between absorbance and pH affect the pH measurement precision of absorption-based optic sensors and limit their application. Based on the preparation of a transparent sol–gel thin film with a phenol red indicator, this work assumed that the absorbancies had an exponential relationship to the concentrations of the indicator, and the multi-wavelength equation for the pH was derived as follows:
where n is the exponential coefficient, e1, e2, and e3 are the extinction coefficient ratios, and R is the ratio of the absorbancies. The calculation parameters for an immobilized phenol red film were pKa = 8.577, e1 = 0.0191, e2 = 1.530, e3 = 0.2992, and n = 0.6322, while those for an immobilized phenol red/Triton X-100 film were pKa = 8.612, e1 = 0.0507, e2 = 1.501, e3 = 0.3687, and n = 0.3931. The correspondence between the calculated pKa and the pKa from the calibration curve verifies the equation. The calculation parameters remain stable as the indicator content is increased, but change with an increase in the Triton X-100 content. Using the equation, the calculated pH shows stable behavior over a long duration regardless of dye leakage, and the calculated precision is 0.0053. The method provides drift-free and precise water pH measurements for R that is not dependent on the total concentration of the indicator, and can be applied to online monitoring.
研究领域:
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
ACS Photonics
·
2024
·
IF 6.5
Xiaoting Wang,Qianxi Yin,Rongrong Xu,Yu Gu,Xianliang Huang,Mulin Li,Teng Ma,Ziyi Chen,Jun Chen,Haibo Zeng
Birefringent crystals have the ability to modulate polarized light, which has important applications in the field of optoelectronics. Waveplates are important devices in polarization optics to modulate the polarization and phase delay of light over a wide band of wavelength. However, conventional designs of half-wave plates and quarter-wave plates involve multiple birefringent crystals, and the fabrication process is complex and costly. Here, we report the discovery of a multiwavelength (532–785 nm) temperature-controlled phase modulator based on Cs4PbBr6/CsPbBr3 perovskite crystals. It is the crystal lattice expansion that is causing the variation of the birefringence factor of Cs4PbBr6/CsPbBr3 through observing crystal optical properties. The transmitted 633 nm light can be temperature-modulated to achieve the switching of optical polarization states between circularly polarized and linearly polarized states, revealing that the same crystal can switch between the functions of half-wave plates and quarter-wave plates. Other wavelengths of transmitted light can also change optical polarization states through temperature control. Given the versatility of halide perovskite-based crystals, Cs4PbBr6/CsPbBr3 crystals offer a promising approach for producing waveplates and other optical devices at a lower cost.
研究领域:
光学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Sensors
·
2024
·
IF 8.2
Yuqing Gu,Jiayi Wang,Zhewen Luo,Xingyi Luo,Linley Li Lin,Shuang Ni,Cong Wang,Haoran Chen,Zehou Su,Yao Lu,Li-Yong Gan,Zhou Chen,Jian Ye
Label-free surface-enhanced Raman spectroscopy (SERS) is capable of capturing rich compositional information from complex biosamples by providing vibrational spectra that are crucial for biosample identification. However, increasing complexity and subtle variations in biological media can diminish the discrimination accuracy of traditional SERS excited by a single laser wavelength. Herein, we introduce a multiwavelength SERS approach combined with machine learning (ML)-based classification to improve the discrimination accuracy of human urine specimens for bladder cancer (BCa) diagnosis. This strategy leverages the excitation-wavelength-dependent SERS spectral profiles of complex matrices, which are mainly attributed to wavelength-related vibrational changes in individual analytes and differences in the variation ratios of SERS intensity across different wavelengths among various analytes. By capturing SERS fingerprints under multiple excitation wavelengths, we can acquire more comprehensive and unique chemical information on complex samples. Further experimental examinations with clinical urine specimens, supported by ML algorithms, demonstrate the effectiveness of this multiwavelength strategy and improve the diagnostic accuracy of BCa and staging of its invasion with SERS spectra from increasing numbers of wavelengths. The multiwavelength SERS holds promise as a convenient, cost-effective, and broadly applicable technique for the precise identification of complex matrices and diagnosis of diseases based on body fluids.
研究领域:
医学诊断
·
光谱学
·
生物信息学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanophotonics
·
2019
·Vol. 9
·期 1
·123-131
·
IF 6.908
Yan Zuo,Yerun Gao,Shiyu Qin,Zhenye Wang,De Zhou,Zhen Li,Yu Yu,Ming Shao,Xinliang Zhang
Two-dimensional (2D) materials were widely used in sensing owing to the tunable physical or chemical properties. For years, optical sensing attracted a massive amount of attention on account of high accuracy, high security, non-invasive measurement, and strong anti-interference ability. Among the various optical sensing schemes, multi-wavelength optical sensing (MWOS) is an important branch and widely adopted in optical image, spectroscopy, or bio/chemical research. However, no spectral selectivity, limited working wavelength range, or intrinsic instability makes conventional 2D materials unsuitable for MWOS. A new class of 2D materials, known as MXene, exhibits outstanding electronic, optical, and thermal properties, leading to new applications in optical sensing. In this paper, we propose an integrated photothermal optical sensor (PHOS) using Ti 3 C 2 T x MXene films. Thanks to the inherent spectral dependence of Ti 3 C 2 T x MXene over a broadband range, the proposed PHOS can respond to different wavelengths from visible to short-wavelength infrared. Because of the efficient photothermal conversion, the PHOS has a control efficiency up to 0.19 π · mW −1 · mm −1 under 980-nm laser pumping and shows a higher control efficiency under red light (690 nm) irradiation. The measured response time of the proposed PHOS is 23.4 μs. This paper brings MXene into chip-integrated optical sensing fields for the first time and shows the potential applications.
研究领域:
材料科学
·
光学工程
·
传感器技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Xu Yang,Jiaju Wu,Ying Liu,Miao Yu,Yong Li,Liping Zhao,Cheng Li,Maohui Yuan
Yb 3+ -Mn 2+ dimer based upconversion nanocrystals (UCNCs) have great prospects in biological and photonic applications. In this work, the broadband upconversion luminescence (UCL) of Yb 3+ -Mn 2+ dimer in perovskite nanocrystals is systematically engineered under multi-wavelength excitations. Under the excitation of 980, 940 and 915 nm lasers, KCdF 3 :Yb 3+ /Mn 2+ UCNCs generate yellow broadband UCL from Yb 3+ -Mn 2+ dimer at room temperature and achieve maximum intensity as Mn 2+ concentration reaches 7.5 mol%. By introducing Er 3+ ions into the KCdF 3 host matrix, the UCL color can be further tuned to pure red with high spectral purity, and the red-to-green (R/G) UC intensity ratio is promoted dramatically. The bidirectional energy transfer (ET) processes between Yb 3+ -Mn 2+ dimer, Mn 2+ and Er 3+ ions facilitate color modulation, supported by power dependence and lifetime measurements. Especially, the ET efficiency is evaluated under the multi-wavelength excitations, confirming the high efficiency of ET processes from Yb 3+ -Mn 2+ dimer to Er 3+ ions. Moreover, the obtained KCdF 3 :Yb 3+ /Mn 2+ /Er 3+ UCNCs present a maximum magnetization intensity of 2.01 emu/g when Mn 2+ concentration reaches 98.5 mol%. Both the tunable UCL and excellent paramagnetism properties indicate that these KCdF 3 :Yb 3+ /Mn 2+ /Er 3+ UCNCs have the capability of bifunctional biomarkers of nanomaterials and can be a candidate for bio-related applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Yang Hu,Wei Liu,Yan Sun
Artificial nano/micromotors that represent the next-generation automotive microdevices hold considerable promise in various potential applications. However, it is a great challenge to design light-powered micro/nanomotors with effective propulsion that can fulfill diverse tasks. Herein, a multilight-responsive micromotor is fabricated by in situ precipitation of photothermal Fe3O4 nanoparticles (NPs) onto different microparticles. The composites exhibit phototactic swarming movement by irradiation at 320–550 nm, which can be reversibly and remotely manipulated by irradiation position, “on/off” switch, and light intensity. The micromotor made of Fe3O4@poly(glycidyl methacrylate)/polystyrene (Fe3O4@PGS) core–shell particles presents a propulsion speed as high as 270 μm/s under ultraviolet (UV) irradiation. Using an array of experimental methods and numerical simulations, thermal convection mechanism is proposed for the propulsion. Namely, under light irradiation, the photogenerated heat on Fe3O4 NPs decreases the density of the irradiated spot, leading to the swarming motion of the composite particles propelled by a “hydrodynamic drag” toward the light spot. Then, Fe3O4@PGS is exploited as a platform for performing “chemistry-on-the-fly” using both the catalytic efficiency of Fe3O4 NPs and an immobilized enzyme (lipase). It is found that the propulsion increases the catalytic efficiency of Fe3O4 NPs for rhodamine B degradation by over 10 times under sunlight. Moreover, it is proved to accelerate the enzymatic reactions of lipase on Fe3O4@PGS in both aqueous and organic systems by more than 50%. Such a multiwavelength phototactic swimmer paves the way to the design of advanced micromotors for various applications, such as drug delivery, microsurgery, and sensing.
研究领域:
纳米技术
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Yuefeng Liu,Jun Zhao,Yan Zhang,Huafang Zhang,Zhenlong Zhang,Huiping Gao,Yanli Mao
Upconversion nanoparticles (UCNPs) doped with lanthanide ions have potential applications in biomedical, solar cells and displays. However, the intensity of the upconversion luminescence (UCL) is limited by the surface effects of nanomaterials , lattice defects, etc. Here, a novel α-NaErF 4 hollow nanocube is fabricated by using divalent manganese ions (Mn 2+ ) to substitute trivalent erbium ions (Er 3+ ) in the NaErF 4 matrix. The hollow-shell structure can weaken the luminescence quenching and surface quenching effects, reduce the energy loss of higher energy levels in nanoparticles , and improve the light capture ability of nanoparticles. So the UCL of α-NaErF 4 hollow nanocubes is greatly improved, which is 14, 790 and 1071 times higher than that of the β-NaErF 4 under 808, 980 and 1530 nm laser excitation, respectively, and the emission in the red region is enhanced respectively by 69, 2049 and 2902 times. In particular, the hollow nanocubes emit intense single-band red emission under the three different wavelengths, respectively. Moreover, the magnetization of α-NaErF 4 hollow nanocubes is 2.16 emu g −1 at room temperature, which is larger than that of gadolinium-based materials. Hollow-shell structure, excellent paramagnetism and single-band red upconversion emission excited by various wavelengths will create NaErF 4 :40Mn UCNPs a good application prospect in the biomedical field.
研究领域:
纳米材料
·
生物医学工程
·
光学材料
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Wei-Yu Jia,Kai-Xin Xie,Rui-Ping Huo,Xiu-Li Song
Plasmonic regulation introduced by metallic nanoparticles is a useful method to improve the detection performance of plasmon-based systems. Herein, we observed a unique enhancement of surface plasmon-coupled emission (SPCE) using plate-shaped plasmonic nanostructures. By assembling Au nanoplates (Au NPLs) via electrostatic adsorption between the Au nanofilm and the quantum dot (QD) layer (630 nm), the fluorescence signal of SPCE was enhanced 90 times more than that of normal SPCE after the conditions were optimized. This enhancement was mainly induced by the intense localized electromagnetic field at the tip of Au NPLs and a novel plasmonic distribution around the “hot-spot” structure between the nanoparticle and Au nanofilm. These effectively mitigated the inherent signal quenching of SPCE and enhanced the emission signal of ultrathin samples on the surface of the NPL-modified Au nanofilm structure. This strategy can be used to improve the detection sensitivity and information integrity of SPCE-based biosensing and bioimaging systems containing ultrathin luminous layers. The different enhancement efficiencies for multiwavelengths were successfully obtained through various emission angles in light of the wavelength resolution of SPCE, thus verifying the existence and importance of energy-matching coupling, and the emission for the fluorophore with low excitation efficiency could also be detected. Benefiting from this, the Au NPL-modulated SPCE system could be a candidate for simultaneous multiwavelength enhancement and high-throughput detection in multicomponent analysis.
研究领域:
纳米生物学
·
光学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2023
·
IF 6.2
Kai-Xin Xie,Rui-Ping Huo,Xiu-Li Song,Qiao-Ling Liu,Yue Jiang,Yu-Han Li,Lu-Lu Dong,Jia-Xin Cheng
Surface plasmon coupled emission (SPCE), a novel surface-enhanced fluorescence technique, can generate directional and amplified radiation by the intense interaction between fluorophores and surface plasmons (SPs) of metallic nanofilms . For plasmon-based optical systems, the strong interaction between localized and propagating SPs and “hot spot” structures show great potential to significantly improve the electromagnetic (EM) field and modulate optical properties . Au nanobipyramids (NBPs) with two sharp apexes to enhance and restrict the EM field were introduced through electrostatic adsorption to achieve a mediated fluorescence system, and the emission signal enhancement was realized by factors over 60 compared with the normal SPCE. It has been demonstrated that the intense EM field produced by the NBPs assembly is what triggered the unique enhancement of SPCE by Au NBPs, which effectively overcomes the inherent signal quenching of SPCE for ultrathin sample detection. This remarkable enhanced strategy offers the chance to improve the detection sensitivity for plasmon-based biosensing and detection systems, and expand the range of applications for SPCE in bioimaging with more comprehensive and detailed information acquisition. The enhancement efficiency for various emission wavelengths was investigated in light of the wavelength resolution of SPCE, and it was discovered that enhanced emission for multi-wavelength could be successfully detected through the different emission angles due to the angular displacement caused by wavelength change. Benefit from this, the Au NBP modulated SPCE system was employed for multi-wavelength simultaneous enhancement detection under a single collection angle, which could broaden the application of SPCE in simultaneous sensing and imaging for multi-analytes, and expected to be used for high throughput detection of multi-component analysis.
研究领域:
生物光学
·
纳米技术
·
分析化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）