Matter
·
2022
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IF 19.967
Jianyong Wan,Jiaxiu Wang,Hongda Guo,Keliang Wan,Xinpeng Zhao,Jian Li,Shujun Li,Zhijun Chen,Shouxin Liu,Kai Zhang
Summary Photothermal materials, especially photothermal plastics, are crucial building blocks for functional devices. Covalently immobilizing the photothermal carbon dots in plastic matrix is a promising method for producing efficient photothermal plastics. However, the reactive moieties of photothermal carbon dots are often destroyed because of harsh preparation conditions, preventing their covalent interaction with plastic matrix. Here, we conceptualized carbon dots with photocaged reactivity (P-CDs) for producing ultra-stable photothermal plastics. During the formation of P-CDs, hydroxyl moieties were maintained in the preparation environment. Upon UV irradiation, hydroxyl moieties of P-CDs were in situ converted into aldehyde groups and reacted with amino groups in the polysaccharide matrix, producing P-CD plastics. As-obtained P-CD plastics showed strong stability against solution immersion and UV aging. In particular, the P-CD plastics showed a high photothermal conversion efficiency of 46.6%. Such efficient and robust photothermal P-CD plastics were further applied to prepare a solar-driven thermoelectric generator (TEG) for energy generation.
研究领域:
材料科学
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纳米技术
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能源材料
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光热转换
✓ 已验证
DOI
高影响因子
Nano Today
·
2024
·
IF 13.2
Fanqiang Bu,Mengnan Liu,Wangtao Zhao,Fang Liu,Wensheng Xie,Guofeng Li,Xing Wang
Combating bacterial biofilm poses a significant challenge because of the dense extracellular polymeric substance (EPS) barrier and inherent drug tolerance. Herein, the designed core-shell nanoparticles (DA 3 -NPs) that eradicate biofilm by precise in-situ phototherapy are reported. DA 3 -NPs are self-assembled using thermosensitive azo-polymers (AP 3 ) to encapsulate GSH-degradable phototherapeutic polymers (DBP) via charge interaction. Notably, D -aminoalanine grafted onto the AP 3 serves as a critical component, providing an electroneutral shell and bacterial peptidoglycan targeting ability to the DA 3 -NPs. Consequently, DA 3 -NPs effectively penetrate EPS up to a depth of 60 µm and precisely target the bacteria within the biofilms. Upon exposure to laser irradiation and the GSH microenvironment, DA 3 -NPs undergo sequential responses involving shell detachment and core disintegration. These processes facilitate point-to-point bacterial killing through the in-situ generations of ROS, carbon radicals and heat damage to the internal bacteria. Compared to non-targeted nanoparticles, DA 3 -NPs exhibit a 61-fold increase in biofilm removal efficiency. This study thus presents a precise in-situ phototherapy strategy for nonantibiotic treatment of biofilm infections.
研究领域:
纳米技术
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生物医学工程
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微生物学
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药学
✓ 已验证
DOI
高影响因子
BIOFOULING
·
2021
·
IF 3.209
Huai-Zhi Luo,Jin-Wei Zhou,Bing Sun,Huan Jiang,Shi Tang,Ai-Qun Jia
Serratia marcescens NJ01, a Gram-negative bacterium, can infect tomato leaves and cause chlorosis and wilting. The present study evaluated the quorum sensing (QS) and biofilm inhibitory effects of seven carboline compounds against S. marcescens NJ01 at 20 μg ml−1, and subsequently focused the study on norharmane as this had the best inhibitory activity. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis confirmed the down-regulation of QS and biofilm related genes bsmA, bsmB, fimA, fimC, flhD, pigA, pigC and shlA on exposure to norharmane. Fourier-Transform Infrared Spectroscopy (FT-IR) analysis showed a reduction in the major components of the exopolysaccharide (EPS) matrix such as nucleic acids, proteins and fatty acids, which are involved in forming the tertiary structure of biofilms. Norharmane exposure also enhanced the susceptibility of the biofilm to ofloxacin. Hence, norharmane has the potential for use as an antibiotic adjuvant to enhance the efficacy of conventional antibiotics to reduce pathogenic bacterial infections.
研究领域:
微生物学
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药理学
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植物病理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Wenjing Yang,Shikai Zhang,Chenchen Li,Mei Li,Yijing Li,Peng Wu,Houshen Li,Shiyun Ai
Polysaccharide-based films have received increasing attention as promising candidates for petrochemical plastics. However, they are highly brittle, poorly hydrophobic and without antibacterial activity, while current films used to address these issues often struggle to manage the balance between these properties. To achieve a balance of several performance indices of the films, functionalized dialdehyde cellulose nanocrystals (DCNCs) were prepared to activate pectin-based films. Structural characterization including dynamic light scattering techniques (DLS), scanning electron microscope (SEM), atomic force microscope (AFM), attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectrometer and x-ray diffraction (XRD) demonstrated that DCNCs were homogeneously dispersed in the pectin polysaccharide matrix and tightly cross-linked through hydrogen bonding interactions, which promoted the stable formation of high-performance composite films. Compared to pure pectin film, the composite film has better tensile strength (23.09 MPa), water contact angle (WCA, 91.23°), water vapor permeability (WVP, 1.02 × 10 −12 g/cm·s·Pa), and exhibit excellent UV-resistance, DPPH radical scavenging capacity (27.04 %) and antibacterial activity that significantly extended the shelf life of strawberries (5 d). Furthermore, DCNCs can be used to enhance the mechanical strength (4.15–23.46 MPa), WVP (1.55–5.21 × 10 −12 g/cm·s·Pa) and WCA (59.46°–61.03°) of various polysaccharide-based films, which validates their universality. This work effectively improves and balances the several properties of polysaccharide-based films, creating more opportunities for the wide application of polysaccharide-based films, such as food preservation packaging.
研究领域:
材料科学
·
食品科学
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纳米技术
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包装工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）