INFRARED PHYSICS & TECHNOLOGY
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2025
·
IF 3.4
Jun Hu,Xiaodong Mao,Zhikai Huang,Shimin Yang
Objective Carbendazim is widely used as an effective fungicide in agriculture, but its residues on crops pose potential health risks to consumers. This study aims to develop a rapid, non-destructive, and highly sensitive method for detecting carbendazim residues. Methods Based on electromagnetic theory, this paper presented a terahertz metamaterial sensor incorporating a “cross” compound double-peak structure. Terahertz transmission spectra were collected from 21 different concentration gradients of carbendazim solutions. The spectral response showed a clear decreasing trend in transmission peak amplitude with increasing concentrations. By comparing the results of data preprocessing and feature extraction, the optimal model of terahertz metamaterial detection of carbendazim residue was established. Result The related coefficient of prediction set (R P ) and root mean square error of prediction set (RMSEP) of this model are 0.9825 and 0.2001, and the Limit of Detection (LOD) is 0.672 μg/mL. Conclusion The results demonstrate the feasibility of using terahertz metamaterial sensors combined with spectral analysis for high-sensitivity, non-destructive detection of carbendazim, offering a promising approach for food safety monitoring.
研究领域:
分析化学
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食品安全
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传感器
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农药残留检测
·
太赫兹技术
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yujiao Tu,Jiaxuan Liu,Xintao Cui,Lei Jinag,Lin Yuan,Wensi Ma,Xiuling Ji
Carbendazim is primarily employed to manage crop diseases. However, excessive pesticide usage poses risks to human health. Therefore, developing a highly sensitive detection method for carbendazim is essential. Nitrogen-doped carbon dots Rhp-N CDs were synthesized through a straightforward one-step hydrothermal process, using Rhizoma paridis extracts and o -phenylenediamine as precursors. Rhp-N CDs were purified using dialysis, thin-layer chromatography, and column chromatography. Transmission electron microscopy revealed that the Rhp-N CDs displayed a spherical morphology with an average particle size of 2.19 nm. X-ray photoelectron spectroscopy analysis indicated that they were composed of carbon (C), nitrogen (N), and oxygen (O) elements. Fourier transform infrared spectroscopy showed that Rhp-N CDs contained amino groups on their surface. The linear ranges of carbendazim detection were 0–50 μg/L and 50–150 μg/L, with low detection limits of 6.81 ng/L and 20.9 ng/L, respectively. Furthermore, the fluorescence quenching mechanism of the target on Rhp-N CDs was elucidated. The nano-fluorescent probe was demonstrated to be effective in determining the content of carbendazim in samples of Snow pears, Winter jujubes, Snow peaches, and Bananas, thereby illustrating the possibility of its practical application.
研究领域:
分析化学
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环境科学
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纳米技术
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农业科学
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DOI
高影响因子
CHEMICAL PAPERS
·
2025
·
IF 2.5
Chen Yufeng,Li Yutong
A novel surface-enhanced Raman scattering (SERS) substrate was developed to determination of the pesticide carbendazim (CBZ) through the green synthesis of silver nanoparticles (SA-AgNPs-CD) using sodium alginate as a reducing agent and α-cyclodextrin as a molecular recognition stabilizer. The composite material was systematically characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD) and UV–vis spectroscopy. The analysis revealed spherical nanoparticles with an average diameter of approximately 59 nm and localized surface plasmon resonance at 412 nm. 4-aminothiophenol (PATP) was used as a SERS probe to discuss the SERS activity of the substrate and multivariate optimization of detection parameters (substrate–analyte ratio 3:1, pH 6.8, 15 min adsorption, and sequential reagent addition) via orthogonal experimental design. The linear response which extends from 5.0 × 10 −5 to 1.0 × 10 −7 mol/L for CBZ combined with principal component analysis (PCA) revealed an ideal linear relationship between CBZ concentration and principal component F 1 , achieving a limit of detection (LOD) of 1.95 × 10 −9 mol/L. It is expected that this SERS strategy will provide great value for rapid detecting pesticide residues in fruits and food products.
研究领域:
分析化学
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纳米技术
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环境科学
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食品安全
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Kanru Fu,Zhengri Cong,Xinghao Wang,Haocheng Sun,Yong Zhang
Natural balsawood with quick-growing, light-weight and porous structure expects to be a carrier of self-supporting electrode for convenient pesticide residue analysis in food. In this work, the hydrangea-like Ni Ti layered double hydroxide (NiTi-LDH) is in-situ synthesized on the balsawood@few-layer Ti 3 C 2 T x nanosheets. The pyrolysis of such precursor leads to the carbonized balsawood@Ti 3 C 2 T x supported pompon-like Ni nanoparticles@N-doped carbon (CW@Ti 3 C 2 T x -NiNPs@NC), which demonstrates the two main structural advantages including the CW@Ti 3 C 2 T x with porous structure as the high-performance substrate and the NC immobilized the high-density distribution of NiNPs as the efficient electrocatalyst. These extraordinary characteristics of CW@Ti 3 C 2 T x -NiNPs@NC contribute to the outstanding electrochemical behaviors for detecting the low-concentration carbendazim (CBZ) pesticide, resulting in 0.36 nM of detection limit and the two-stage linear detection ranges including 1–250 nM and 0.25–20.00 μM. More importantly, such CW@Ti 3 C 2 T x -NiNPs@NC with free-cutting can be directly utilized as the quickly replaceable working electrode to create a prototype of portable sensor with the self-designed electronic system. Furthermore, a rapid sampling process matched such portable electrochemical sensor is proposed for the quick detection of residual CBZ on the surfaces of vegetables and fruits. Our research proposes a method to construct the high-performance self-supporting electrode on the basis of natural balsawood@Ti 3 C 2 T x nanosheets for electrochemical sensing.
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高影响因子
Foods
·
2022
·Vol. 11
·期 9
·1287
·
IF 5.561
Xiaowei Huang,Ning Zhang,Zhihua Li,Jiyong Shi,Haroon Elrasheid Tahir,Yue Sun,Yang Zhang,Xinai Zhang,Melvin Holmes,Xiaobo Zou
In order to achieve rapid and precise quantification detection of carbendazim residues, surface-enhanced Raman spectroscopy (SERS) combined with variable selected regression methods were developed. A higher sensitivity and greater density of “hot spots” in three-dimensional (3D) SERS substrates based on silver nanoparticles compound polyacrylonitrile (Ag-NPs @PAN) nanohump arrays were fabricated to capture and amplify the SERS signal of carbendazim. Four Raman spectral variable selection regression models were established and comparatively assessed. The results showed that the bootstrapping soft shrinkage-partial least squares (BOSS-PLS) method achieved the best predictive capacity after variable selection, and the final BOSS-PLS model has the correlation coefficient (RP) of 0.992. Then, this method used to detect the carbendazim residue in apple samples; the recoveries were 86~116%, and relative standard deviation (RSD) is less than 10%. The 3D SERS substrates combined with the BOSS-PLS algorithm can deliver a simple and accurate method for trace detection of carbendazim residues in apples.Keywords:apple;carbendazim;surface-enhanced Raman spectroscopy (SERS);Ag-NPs @PAN-nanohump arrays;bootstrapping soft shrinkage-partial least squares (BOSS-PLS)
研究领域:
食品安全
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分析化学
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DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2021
·
IF 5.279
Chuanyu Han,Zhiyin Yu,Yuting Zhang,Zhiyan Wang,Junwei Zhao,Sheng-Xiong Huang,Zhonghua Ma,Ziyue Wen,Chongxi Liu,Wensheng Xiang
In this study, the supernatant extract from fermentation broth of Streptomyces sp. NEAU-H3 showed strong antifungal activity against Fusarium graminearum strain PH-1 in vitro and in vivo. Three known pyranonaphthoquinones were isolated by means of an activity-guided method, and frenolicin B was characterized as the main active ingredient. Frenolicin B displayed strong antifungal activity against F. graminearum strain PH-1 with an EC50 value of 0.51 mg/L, which is lower than that of carbendazim (0.78 mg/L) but higher than that of phenamacril (0.18 mg/L). Frenolicin B could also strongly inhibit the mycelial growth of Fusarium species, including F. graminearum and F. asiaticum, as well as carbendazim-resistant Fusarium strains isolated from field, with EC50 values of 0.25–0.92 mg/L. Results from field experiments showed that the efficacy of frenolicin B in controlling Fusarium head blight at a treatment concentration of 75 g ai/ha was better than those of phenamacril (375 g ai/ha) and carbendazim (600 g ai/ha) or had no significant difference with that of phenamacril (375 g ai/ha) in 2 years. Scanning electron microscope and transmission electron microscope observations revealed that after treating F. graminearum mycelia with frenolicin B, the mycelia appeared aberrant and had an uneven thickness and swelling, the cytoplasm had disintegrated, and some cell contents were lost. Transcriptome analysis suggests that frenolicin B might inhibit the metabolism of nucleotides and energy by affecting genes involved in phosphorus utilization but did not affect the expression of myosin 5, which is the specific target of phenamacril. These findings indicate that frenolicin B may be a potential agrochemical fungicide for controlling Fusarium head blight.
研究领域:
农业
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植物病理学
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微生物学
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分子生物学
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DOI
PubMed
高影响因子
MATERIALS RESEARCH INNOVATIONS
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2025
·
IF 0
Mengyuan Zhao,Tingting Wu,Jiale Han,Fang Li,Hongyuan Zhao
This work designed a low-cost and sensitive electrochemical sensor based on chitosan (CTS)-modified peanut shell-derived porous carbon (PSPC) for the detection of carbendazim (CBZ). PSPC exhibited a unique three-dimensional interconnected porous structure. The hierarchical porous carbon architecture with high specific surface area not only enhanced the adsorption capacity of CBZ but also significantly increased the interface contact area of electrode/electrolyte. CTS was uniformly deposited on the surface of PSPC via ultrasound-assisted liquid-phase dispersion method for the preparation of the PSPC@CTS nanocomposite. Benefiting from the good biocompatibility, adsorption ability and film-forming property of CTS, the PSPC@CTS modified electrode demonstrated good CBZ enrichment ability and improved structural stability. The PSPC@CTS/GCE sensor exhibited a low detection limit of 17.41 nM (S/N = 3) within the linear CBZ concentration range of 0.01–10.0 µM. Satisfactory recoveries of 96.78 –100.42% could validate its practical application potential of the PSPC@CTS modified sensor for the CBZ detection in food samples.
研究领域:
环境科学
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材料科学
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分析化学
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电化学
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纳米技术
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DOI
BIOMEDICAL CHROMATOGRAPHY
·
2024
·Vol. 38
·期 9
·e5935
·
IF 1.8
Feng Lan,Xinyu Wang,Xuejing Wang,Yinwei Ruan,Li Ding,Daliang Liu,Tongliang Zhang,Jianping Wang
Dissipative behavior and final residue levels of difenoconazole, prochloraz, propiconazole, and pyraclostrobin in figs were investigated using field trials and laboratory assays. A three-factor, three-level orthogonal test was designed to optimize the pretreatment conditions of the method. A method was established using high-performance liquid chromatography tandem mass spectrometry for the determination of difenoconazole, prochloraz, propiconazole, and pyraclostrobin residues in figs. The limit of quantification for all four targets in figs was 0.002 mg/kg. Difenoconazole, prochloraz, propiconazole, and pyraclostrobin are readily digestible pesticides in figs with half-lives of 6.4, 6.2, 4.8, and 7.9 days, respectively. Residues of difenoconazole, prochloraz, propiconazole, and pyraclostrobin in figs were below the European Union established residue levels of 0.1, 0.03, 0.01, and 0.02 mg/kg, respectively, at day 7 after application. Pyraclostrobin, propiconazole, difenoconazole, and prochloraz were applied twice at doses of 75, 125, 150, and 200 mg a.i./kg at 7-day intervals, and the residues of the four fungicides in figs were acceptable 7 days after the last application. Therefore, the safety interval can be set at 7 days for 70% difenoconazole-prochloraz wettable powder and 40% pyraclostrobin-propiconazole aqueous emulsion according to the protocol.
研究领域:
食品科学
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分析化学
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植物保护
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DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 13
·19396-19408
·
IF 0
Pan Enzhuang,Xin Yue,Li Xueqing,Ping Kaixin,Li Xing,Sun Ying,Xu Xuhui,Dong Jingquan
As a broad-spectrum and efficient triazole fungicide, difenoconazole is widely used, which not only pollutes the environment but also exerts toxic effects on non-target organisms. The spleen plays an important role in immune protection as an important secondary lymphoid organ in carp. In this study, we assessed the protective impact of silybin as a dietary additive on spleen tissues of carp during exposure to difenoconazole. Sixty carp were separated into four groups for this investigation including control group, difenoconazole group, silybin group, and silybin and difenoconazole group. By hematoxylin-eosin staining, dihydroethidium staining, immunohistochemical staining, terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling assay, quantitative real-time PCR assay, Western blot analysis, biochemical assays, and immune function indicator assays, we found that silybin could prevent difenoconazole-induced spleen tissue damage, oxidative stress, and immune dysfunction, and inhibited apoptosis of carp spleen tissue cells by suppressing the formation of p53-driven caspase-9-apoptotic protease activating factor-1-cytochrome C complex. The results suggested that silybin as a dietary additive could improve spleen tissue damage and immune dysfunction induced by difenoconazole in aquaculture carp.
研究领域:
环境毒理学
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免疫学
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水产养殖学
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DOI
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Sheng Gong,Fan Nie,Lingxuan Ma,Jiali Wan,Yu Yang,Wensheng Zhang,Jinchao Wei,Peng Li
The overuse of pesticides poses a significant threat to human health, driving the need for accurate and rapid strategies to identify various pesticides. A fluorescent nano-sensor (R-AuNCs@Aptamer) was developed by integrating an amino-modified carbendazim aptamer with red-colored gold nanoclusters (R-AuNCs). We subsequently engineered an aptamer-triggered turn-off-on Förster resonance energy transfer (FRET) platform, employing R-AuNCs@Aptamer in conjunction with tungsten disulfide nanosheets (WS 2 NS). In this setup, the carbendazim aptamer-stabilized red-emitting R-AuNCs (∼655 nm) served as the energy donor, while WS 2 NS acted as a fluorescence quencher. Upon the introduction of carbendazim, alterations in fluorescence intensity were monitored at 655 nm, facilitating the recognition of carbendazim. The resulting fluorescent nano-sensor displayed outstanding selectivity towards carbendazim, exhibiting a broad detection range of 0.1 to 1000 μg/L and remarkable sensitivity with a low limit of detection. It demonstrated reliability and practicality when applied to Notoginseng Radix et Rhizoma and Ginseng Radix et Rhizoma samples, with recoveries ranging from 90 % to 110 %. By changing the aptamer sequence, this sensor can be customized to detect different pollutants, exhibiting excellent tailorability and broad application potential.
研究领域:
分析化学
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纳米技术
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环境科学
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生物传感器
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食品安全
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DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Xuemei He,Xiaoyao Luo,Licheng Chen,Yanxia Li,Tingting Sun,Wei Xiao,Wenmin Wang,Jianhua Xiong,Xiaoning Liao
Benomyl (BEN) was widely employed in agriculture as an efficient broad-spectrum benzimidazole fungicide. However, overuse of BEN aroused extensive human health concerns. Electrochemical sensors are promising techniques for residue analysis but are seriously limited by insufficient sensitivity and electrode contamination in BEN detection. Herein, an electrochemical sensor based on Au nanoparticles and MWCNTs-COOH co-modified black phosphorus (BP) was developed for BEN detection. This unique heterostructure of BP-Au/MWCNTs-COOH significantly enhanced the electrochemically active surface area (EASA), charge transfer efficiency, and antifouling effect. The fabricated BP-Au/MWCNTs-COOH/GCE electrochemical sensor demonstrated good analytical performances with a wide linear range (0.007–1.0 μM), ultralow detection limit (1.54 nM), high repeatability, good selectivity and long-term stability. In addition, the sensor achieved high recoveries of 97.36–114.3 % in real food samples, highlighting its potential for rapid and trace-level monitoring of BEN in agricultural products.
研究领域:
电化学
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纳米技术
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食品安全
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环境监测
·
农业化学
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Wen Jiang,Jia Zheng,Jian Su,Yue Tang,Yuangen Wu,Yating Cao,Wentao Cao
Colorimetric methods have the benefits of rapid detection and easy operation in dimethoate (DMT) analysis. However, the existing colorimetric sensor for DMT detection still face challenges in terms of performance stability and result reliability of sensing materials. Bimetallic Ag 2 CrO 4 nanoparticles (NPs) have been found to have both oxidase-mimic and laccase-mimic catalytic activities. DMT has opposite effect on the above dual-enzyme-mimic activities, which can enhance oxidase-mimic activity while inhibiting laccase-mimic activity of Ag 2 CrO 4 NPs. Therefore, a novel colorimetric sensor was constructed using the dual-enzyme-mimic activities as a sensing signal for rapidly detecting DMT in vegetables. The concentration of DMT is directly correlated with the absorbance change of the sensing solution, and the color change is further integrated with the smartphone to enable quantitative measurement of DMT. The limits of detection were as low as 8.7 μg L −1 in the oxidase-mimic channel and 10.9 μg L −1 in laccase-mimic channels. Besides, the colorimetric sensor has shown marked preference in selectivity over other competing pesticides, and obtained relatively preferable recovery rates in some vegetables, indicating that the established sensor has a wide range of potential applications in the area of vegetable pesticide detection.
研究领域:
分析化学
·
食品安全
·
纳米技术
·
农药检测
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）