ECOTOXICOLOGY
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2022
·Vol. 31
·期 5
·735-745
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IF 2.935
Wei Xinrong,Li Xiao,Liu Hongsong,Lei Haojun,Sun Weijun,Li Dan,Dong Wu,Chen Hongxing,Xie Lingtian
Cadmium (Cd) is a non-essential element and can be toxic to aquatic organisms at low concentrations. Despite its well-known toxicity to Daphnia magna , the effects of Cd on physiological parameters (heart rate and thoracic limb activity) and molting- and reproduction-related genes are relatively understudied. In this study, D. magna were exposed to 0 (control), 25, 50 and 75 μg L −1 of Cd for 7 d and 21 d to determine the toxicity of Cd. The results showed that the Cd body burden in D. magna was significantly increased with elevated Cd concentrations, up to 13.4 μg Cd/g dry weight (dw) after exposure to 75 μg L −1 for 21 d. After 21 d of exposure, the body length and body weight of D. magna were significantly decreased in all Cd treatments compared to the control. The heart rate and thoracic limb activity were reduced by 4.3–11.7 and 5.0–10.3%, respectively. The levels of malondialdehyde (MDA) were increased by ~24–37% and the activity of catalase (CAT) was inhibited by ~50% compared to the control. The reproductive parameters (i.e., size of the first brood, the total number of offspring per female and the number of offspring per brood) were remarkably reduced, causing adverse effects on the population dynamics. In addition, the transcripts of genes ( cyp314 , cyp18a1 , ecra , usp , hr3 , cut , cht and cht3 ) related to the molting of D. magna were altered, whereas the transcripts of genes ( vtg1 , vtg2 and vmo1 ) related to reproduction were down-regulated. This study helps better understand the effects of Cd at different biological levels.
研究领域:
生态毒理学
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分子生物学
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环境科学
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DOI
PubMed
高影响因子
Water
·
2023
·Vol. 15
·期 9
·1744
·
IF 3.4
Shaolin Qiu,Wenjiao Yuan,Yujie Qin,Xin Feng,Meitong Li,Yuhong Xie
Microplastic pollution is widespread around the world and inevitably comes into contact with organisms. With the accumulation of microplastics in the environment, the negative impact of microplastics on organisms has become the main focus in the field of microplastics. In this study, the different particle and concentration effects of fluorescent polystyrene microplastics (PS-MPs) onNostocaceaeandDaphnia Magnawere researched. The results indicate that PS-MPs adhered toNostocaceaethrough static electricity, which hindered the absorption of photons and CO2byNostocaceae, resulting in a decrease in chlorophyll, a low growth rate and high mortality forNostocaceae. PS-MPs with very small particles may be integrated into the blood ofDaphnia Magna, leading to an increasing trend of mortality and a decrease in spawning rate. The research provides basic data and a reference for the effect of PS-MPs on freshwater organisms and has implications for the further study of microplastics.Keywords:microplastics;fluorescent polystyrene;Nostocaceae;Daphnia Magna;photosynthesis;reproductive effect
研究领域:
环境生物学
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生态毒理学
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DOI
高影响因子
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2025
·Vol. 116
·期 1
·9
·
IF 2.2
Huang Junyun,Liu Boying,Yuan Sijia,Zhou Haiyun,Bao Jian,Tu Yong,Wang Zunyao,Wang Weixia
Benzophenone-3 (BP-3), a widely used ultraviolet filter in personal care products, has been extensively detected in aquatic environments and poses potential ecological risks. This study innovatively investigated the pH-dependent acute toxicity of BP-3 to three model aquatic organisms— Daphnia magna , Photobacterium phosphoreum , and Danio rerio —by determining the EC 50 and LC 50 values across a pH range of 5.0 to 9.0. Our results revealed that BP-3 exerted greater acute toxicity on all three tested aquatic organisms under acidic conditions (pH 5.0) than under alkaline conditions (pH 9.0). The increased toxicity with lower pH was attributed to the predominance of the more lipophilic molecular form of BP-3, emphasizing the significant influence of environmental pH on BP-3 toxicity. These findings provide essential toxicological data for assessing the ecological risks of BP-3 in diverse aquatic environments, highlighting the necessity of considering BP-3 concentration, environmental pH and exposed species in ecological risk assessments.
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PubMed
高影响因子
WATER RESEARCH
·
2022
·
IF 13.4
Ciara Chun Chen,Yihan Shi,Yanjie Zhu,Jiamin Zeng,Wei Qian,Shuang Zhou,Jie Ma,Ke Pan,Yuelu Jiang,Yi Tao,Xiaoshan Zhu
Microplastics (MPs) have worldwide accumulated in aquatic environments and coexisted with various water contaminants including perfluorinated compounds (PFCs) that are frequently detected. The adverse effects of individual MPs or PFCs on aquatic organisms have been extensively reported; however, the combined toxicity of MPs and PFCs remains unknown. This study evaluated the combined toxicity of MPs [pristine and aged polystyrene (PS)] and a PFC [ammonium perfluorooctanoate (APFO)] to Daphnia magna under different concentration ratios by three classic methods: toxicity unit, additive index, and mixed toxicity index. The adsorption kinetics of APFO on MPs, aggregation of MPs in exposure medium, MP gut fullness of daphnids, intestinal histology, and lipid peroxidation were analyzed to reveal the mechanism underlying the combined toxicity. Our results showed that the combined toxic modes varied with the concentration ratios of MPs to APFO (antagonism at 4:1 and 1:4, synergism at 3:1, 1:2, and 1:3, and partial addition/antagonism at 2:1 and 1:1 for pristine PS + APFO; antagonism at all ratios except partial addition/antagonism at 3:1 and 1:3 for aged PS + APFO), which could be attributed to the alteration of MP aggregation and thus MP gut fullness in the daphnids. The combined toxicity was further confirmed to occur in the daphnid's gut, which was reflected in physiological and biochemical responses mediated by intestinal blockage. Observable intestinal damages under co-exposures at μg•L − 1 levels indicated the risks from future long-term exposure to MPs and PFCs in aquatic environments. This work demonstrates the necessity of assessing combined toxicity with different concentration ratios and provides new insights into the potential risks of MPs in aquatic environments.
研究领域:
环境科学
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毒理学
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水生生态学
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DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2019
·
IF 4.527
Matthew Nkoom,Guanghua Lu,Jianchao Liu,Haohan Yang,Huike Dong
Owing to its persistence, carbamazepine an antiepileptic drug is regularly detected in the aquatic environment. The motive for our research was to assess the bioconcentration, physiological and biochemical effects of carbamazepine in Daphnia magna . A 48 h aqueous exposure of carbamazepine yielded bioconcentration factors of 202.56 and 19.95 in Daphnia magna for the respective nominal treatments of 5 and 100 µg/L. Apparently, the inhibition of the capability of Daphnia magna to obtain food attributable to carbamazepine exposure will reduce their fitness to reproduce as well as to grow. Also, a significant alteration in the phototactic behaviour of Daphnia magna exposed to carbamazepine is maladaptive since it will increase their chance of being preyed upon in the surface water during daylight. Again, a significant decline in the acetylcholinesterase activity observed herein brings to light the neurotoxicity of carbamazepine to Daphnia magna . Moreover, significant inhibition of the superoxide dismutase, catalase and glutathione reductase activities coupled with the simultaneous induction of the malondialdehyde content imply that carbamazepine evoked a life-threatening oxidative stress that overpowered the antioxidant defence system of Daphnia magna . These observations confirm that carbamazepine can accumulate and consequently cause negative physiological and biochemical changes to wild Daphnia magna populations.
研究领域:
环境科学
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毒理学
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水生生态学
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DOI
PubMed
高影响因子
ENVIRONMENTAL POLLUTION
·
2023
·
IF 8.9
Jingyi Guo,Na Liu,Qiting Xie,Lizhong Zhu,Fei Ge
Ubiquitous microplastics (MPs) may affect the trophic transfer of nanoparticles (NPs), in turn threatening aquatic organisms and even human health. Thus, this study explored the influence of polystyrene microplastics (PS MPs) on the biotoxicity and biomagnification of ZnO nanoparticles (ZnO NPs) in the aquatic food chain from Chlorella vulgaris ( C. vulgaris ) to Daphnia magna ( D. magna ). The results showed that PS MPs facilitated the biotoxicity of ZnO NPs towards D. magna after dietary exposure. Compared to the control (single ZnO NPs), the heart rate and the level of reactive oxygen species were remarkably increased by 21.25% and 16.32% in the combined system (PS MPs + ZnO NPs), respectively. Notably, PS MPs suppressed the ZnO NPs accumulation in C. vulgaris , while remarkably facilitating the trophic transfer of ZnO NPs to D. magna . The biomagnification of ZnO NPs was evident with a maximal biomagnification factor (BMF) of 1.49 under acute dietary exposure of PS MPs (72 h), but was absent in the single ZnO NPs system (BMF <0.90). Moreover, PS MPs resulted in a larger biomagnification of ZnO NPs with a maximal BMF of 2.11 under chronic dietary exposure (21 days). Furthermore, the Zn element (including ZnO NPs and released Zn 2+ ) was observed to accumulate in the intestine, thus causing ultrastructural damage and lipid droplet (LD) aggregate. Overall, these findings highlight the importance of considering the impact of MPs on co-existed pollutants and contribute to a better understanding of the ecological risks of MPs in aquatic ecosystems .
研究领域:
环境科学
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水生生态学
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纳米毒理学
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Chi Wu,Kai He,Huizhen Li,Lan Zhang,Liangang Mao,Lizhen Zhu,Jinhua Jiang,Xingang Liu
The transgenerational impacts of pesticide mixture on Daphnia magna ( D. magna ) following long-term exposure, particularly regarding transcriptomic effects, remain poorly understood. We analyzed 470 irrigation water samples from various Chinese provinces. Imidacloprid (IMI, 71.1 %), clothianidin (CLO, 60.43 %), and tebuconazole (TEB, 64.68 %) were the most frequently detected pesticides, with nearly 50 % of samples showing mixtures of TEB with IMI or CLO. D. magna were exposed to environmentally relevant concentrations (0.89–1.62 μg/L) over 12 generations. Key effects included reduced fecundity, delayed development, and smaller body size, with these impacts exacerbating across generations. A Leslie matrix model revealed declines in population size, intrinsic rates of increase, and age structure. Notably, mixed pesticide exposures induced specific pathways related to oocyte meiosis, resulting in greater toxicity than single exposures. Additionally, disrupted lipid metabolism and feeding behaviors were linked to insufficient energy for growth and reproduction, affecting ovarian development. These findings highlight the ecological risks of long-term pesticide exposure and offer insights for mitigation strategies in aquatic ecosystems.
研究领域:
生态毒理学
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环境科学
·
水生生态学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）