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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH · 2021 ·Vol. 28 ·期 20 ·25503-25513 · IF 4.223

Wastewater analysis reveals urban, suburban, and rural spatial patterns of illicit drug use in Dalian, China

Cong Zi-Xiang,Shao Xue-Ting,Liu Si-Yu,Pei Wei,Wang De-Gao

Illicit drug use in rural and suburban areas of China has not been studied extensively, as most studies have focused on illicit drug use in urban areas. To compare the differences between urban, suburban, and rural drug use, we collected influent samples from 19 urban, 9 suburban, and 18 rural wastewater treatment plants in Dalian, respectively. A method using solid-phase extraction combined with derivatization for gas chromatography -mass spectrometry analysis was applied to detect biomarker concentrations. The concentrations of methamphetamine and morphine ranged from 3.12 to 605 ng/L and < 2.35 to 198 ng/L, respectively. Norketamine was found in only four samples (5.56 to 14.5 ng/L), while 3,4-methylenedioxymethamphetamine and benzoylecgonine were not detected in any samples. Methamphetamine use in rural areas (16.3 mg/day/1000 inhabitant (inh), prevalence: 0.06%) was significantly lower than those in urban (77.1 mg/day/1000 inh, prevalence: 0.23%) and suburban (234 mg/day/1000 inh, prevalence: 0.70%) areas. Heroin use in suburban areas (57.6 mg/day/1000 inh, prevalence: 0.10%) was significantly higher than that in urban (13.9 mg/day/1000 inh, prevalence: 0.02%) and rural (8.68 mg/day/1000 inh, prevalence: 0.02%) areas. The results indicate relatively low levels of illicit drug use in rural areas of Dalian, related to low incomes and outflow of the working-age population. Illicit drug use was most prevalent in suburban areas of Dalian, which may be influenced by large floating populations and few anti-drug efforts in suburban areas.

CAS / MDL: 25561-30-2
研究领域: 环境科学 · 公共卫生 · 毒理学
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BMC INFECTIOUS DISEASES · 2022 ·Vol. 22 ·期 1 ·1-8 · IF 3.667

Using time-dependent reproduction number to predict turning points of COVID-19 outbreak in Dalian, Liaoning province, China

An Qingyu,Wu Jun,Bai Jin jian,Li Xiaofeng

Objectives To forecast the development trend of current outbreak in Dalian, mainly to predict turning points of COVID-19 outbreak in Dalian, Liaoning province, China, the results can be used to provide a scientific reference for timely adjustment of prevention and control strategies. Methods During the outbreak, Bayesian framework was used to calculated the time-dependent reproduction number ( \({R_{t}}\) ), and then above acquired \({R_{t}}\) and exponential trend equation were used to establish the prediction model, through the model, predict the \({R_{t}}\) value of following data and know when \({R_{t}}\) smaller than 1. Results From July 22 to August 5, 2020, and from March 14 to April 2, 2022, 92 and 632 confirmed cases and asymptomatic infected cases of COVID-19 were reported (324 males and 400 females) in Dalian. The R square for exponential trend equation were 0.982 and 0.980, respectively which fit the \({R_{t}}\) with illness onset between July 19 to July 28, 2020 and between March 5 to March 17, 2022. According to the result of prediction, under the current strength of prevention and control, the \({R_{t}}\) of COVID-19 will drop below 1 till August 2, 2020 and March 26, 2022, respectively in Dalian, one day earlier or later than the actual date. That is, the turning point of the COVID-19 outbreak in Dalian, Liaoning province, China will occur on August 2, 2020 and March 26, 2022. Conclusions Using time-dependent reproduction number values to predict turning points of COVID-19 outbreak in Dalian, Liaoning province, China was effective and reliable on the whole, and the results can be used to establish a sensitive early warning mechanism to guide the timely adjustment of COVID-19 prevention and control strategies.

研究领域: 流行病学 · 公共卫生 · 传染病学 · 生物统计学 · 预测模型 · 疫情防控
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LWT-FOOD SCIENCE AND TECHNOLOGY · 2020 · IF 4.006

Gallic acid and its alkyl esters emerge as effective antioxidants against lipid oxidation during hot air drying process of Ostrea talienwhanensis

Man-Tong Zhao,Zhong-Yuan Liu,Ao Li,Guan-Hua Zhao,Hong-Kai Xie,Da-Yong Zhou,Tong Wang

The antioxidant efficiency of gallic acid (GA) and its alkyl esters including methyl gallate (MG), ethyl gallate (EG), propyl gallate (PG), butyl gallate (BG), octyl gallate (OG), lauryl gallate (LG), hexadecyl gallate (HG), and octadecyl gallate (SG) in oyster tissue during hot-air drying process was investigated. Results indicated that GA and its alkyl esters all could effectively retard lipid oxidation in oyster tissue according to peroxide value (POV), thiobarbituric acid reactive substances (TBARS) and free radical intensity. The antioxidant effects increased with the alkyl chain length until OG, thereafter, it gradually decreased. The POV of the OG treated oysters post 10 h of drying was 66.26, 68.90, 77.86, 92.61, 89.45, 70.79, 68.96 and 62.70%, respectively, of those treated by GA, MG, EG, PG, BG, LG, HG and SG. The corresponding values for TBARS were 68.72, 76.59, 77.88, 84.32, 86.23, 68.31, 81.24, 77.36%, while 41.19, 58.62, 62.83, 64.49, 69.60, 61.44, 60.05 and 72.61% for free radical intensity. Pearson correlation analysis showed a positive correlation between the antioxidant effects and the concentrations of the polyphenol compounds in oyster tissue. This report will provide the basic data for selection of suitable antioxidants to improve the oxidation stability of seafood during thermal processing.

研究领域: 食品科学 · 化学 · 农业科学
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