TALANTA
·
2023
·
IF 6.1
Xuan Ma,Yue Wang,Wenting Wang,Jake Heinlein,Lisa D. Pfefferle,Xuemeng Tian
In this study, a facile method has been developed to synthesize a novel type of porous magnetic molecularly imprinted polymers (Fe 3 O 4 -MER-MMIPs) for the selective adsorption and removal of meropenem. The Fe 3 O 4 -MER-MMIPs, with abundant functional groups and sufficient magnetism for easy separation, are prepared in aqueous solutions. The porous carriers reduce the overall mass of the MMIPs, greatly improving their adsorption capacity per unit mass and optimizing the overall value of the adsorbents. The green preparation conditions, adsorption performance, and physical and chemical properties of Fe 3 O 4 -MER-MMIPs have been carefully studied. The developed submicron materials exhibit a homogeneous morphology, satisfactory superparamagnetism (60 emu g −1 ), large adsorption capacity (11.49 mg g −1 ), quick adsorption kinetics (40 min), and good practical implementation in human serum and environmental water. Finally, the protocol developed in this work delivers a green and feasible method for synthesizing highly efficient adsorbents for the specific adsorption and removal of other antibiotics as well.
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Chinese Journal of Natural Medicines
·
2022
·
IF 3.887
Jun-Jie ZHU,Qi-Sen HUANG,Sheng-Quan LIU,Wei-Jia DING,Ya-Hong XIONG,Chun-Yuan LI
Four new diphenyl ethers, named epicoccethers K−N ( 1 − 4 ), were purified from the fermentation medium of a fungus Epicoccum sorghinum derived from Myoporum bontioides , and identified through HR-ESI-MS and NMR spectral analysis. Except that compound 1 showed moderate antifungal activity against Penicillium italicum and Fusarium graminearum , the other three compounds showed stronger activity against them than triadimefon. All of them showed moderate or weak antibacterial activity towards Staphylococcus aureus and Escherichia coli with O6 and O78 serotypes except that 3 was inactive to E. coli O6.
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DALTON TRANSACTIONS
·
2023
·Vol. 52
·期 19
·6551-6558
·
IF 4
Wenjuan Dong,Lu Wang,Rongrong Zhang,Chaochao Wen,Ren Su,Xiaojuan Gong,Wenting Liang
Carbon dots are popular luminescent materials because of their excellent fluorescence properties, but the low quantum yield limits their application. Heteroatom doping is a more convenient and popular approach to increase the quantum yield of carbon dots. Here, novel N,S,P heteroatom co-doped carbon dots (N,S,P-CDs) were synthesized by a simple one-step hydrothermal method using m-phenylenediamine, L-cysteine and phosphoric acid as raw materials. The as-prepared N,S,P-CDs showed excellent photoluminescence properties with a fluorescence quantum yield of up to 41%, which greatly encourages their application in fluorescence sensing. The N,S,P-CDs exhibited good fluorescence stability under salt solution, xenon lamp irradiation and ultraviolet lamp irradiation except for a high sensitivity to extreme acidity. The fluorescence intensity of the N,S,P-CDs can be decreased by as much as 85% when the pH of the solution changes from 2.50 to 4.75, that is, a small fluctuation in pH can cause an intense response of the fluorescence of the N,S,P-CDs. Therefore, an excellent fluorescence sensing platform for accurately monitoring the pH of extreme acidity has been constructed. In addition, the N,S,P-CDs can be applied for quantitative detection of folic acid based on the strong quenching effect of folic acid on the fluorescence of the N,S,P-CDs. Good linearity was obtained in the concentration range of 4.85–82.45 μM, with a detection limit of 0.148 μM. The constructed sensing platform was used for the determination of folic acid in actual samples of orange juice, oatmeal and tablets with satisfactory results.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Xueqing Guo,Yang Liu,Wenjuan Dong,Qin Hu,Yong Li,Shaomin Shuang,Chuan Dong,Lishuai Cai,Xiaojuan Gong
Azithromycin (AZM) 1 is one of the most widely used antibiotics. AZM abuse is easy to cause great harm to human body, so developing a rapid and sensitive method to detect AZM is of great importance. Herein, 3-aminothiophenol as only reaction precursor, nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) 2 were fabricated by one-step hydrothermal carbonization method. All characteristics demonstrate that N,S-CQDs possess good water solubility, high fluorescence stability and low cytotoxicity. Without being disturbed by amino acids and drugs, the most interesting finding is that AZM can efficiently quench the fluorescence of N,S-CQDs by a synergistic effect of electrostatic interaction and static quenching. A fluorescent probe for the detection of AZM was constructed with high selectivity and good sensitivity, achieving two linear ranges of 2.5–32.3 μM and 37.2–110 μM and a limit of detection of 0.76 µM. The proposed fluorescent method was used for the detection of AZM in cells with fulfilling results. More importantly, the fluorescent probe was successfully used to the detection of AZM in tablets and human urine with recovery rate and relative standard deviations of 98.2–104.8% and 0.04–3.46%, respectively, which was confirmed by the standard method of HPLC-UV. This finding illustrates the usefulness and feasibility of N,S-CQDs as an effective fluorescent probe for the detection of AZM in tablets and human urine, which is helpful for supervising and guiding pharmacy.
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BIOORGANIC CHEMISTRY
·
2021
·
IF 5.275
Junjie Zhu,Ziyang Li,Haihong Lu,Shengquan Liu,Weijia Ding,Jiazhong Li,Yahong Xiong,Chunyuan Li
The strategy “IEMAHC” (Induction of Endophyte Metabolism by Adding Host Components) was applied to the fermentation of the endophytic fungus Epicoccum sorghinum L28 from Myoporum bontioides by introducing guaiol, an ingredient of M. bontioides , into the cultivation medium, which resulted in the purification of nine new diphenyl ethers, epicoccethers A–I ( 1 – 9 ). Their structures were determined by overall spectroscopic analysis. HPLC-MS analysis revealed that compounds 5 – 7 were products generated by induction of guaiol. Compounds 6 and 7 are the first members containing an ester moiety formed by the natural long-chain fatty acid and the hydroxyl group in the phenylmethanol unit of the diphenyl ether class. The antifungal activities of compounds 1 , 2 , and 4 – 7 against Fusarium oxysporum were 1, 1, 2, 1, 2 and 4 times as high as those of the positive control triadimefon, respectively. Compounds 4 and 5 showed 1.6 times the antifungal activities of triadimefon towards Colletotrichum musae .
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JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
·
2021
·
IF 2.262
Fengli Shao,Xu Zhang,Xiantao Sun,Jingge Shang
Biomass waste (Chinese traditional medicine residues) is one of the most promising sources of biochar. Here, the present study illustrated the activated biochar (BCA) was prepared using the herb residue (Astragalus membranaceus) via sodium carbonate (Na2CO3) activation for the removal of Cefradine (CF) in wastewater. The adsorbents were characterized by scanning electron microscopy, N2 adsorption-desorption analysis, Fourier transform infrared spectrum, X-ray diffraction, X-ray photoelectron spectroscopy and zeta potential analysis. The effects of initial pH value, BCA dosage, initial CF concentration and coexisting ion for CF removal were investigated. BCA showed much higher absorption capacity for CF (qm=64.76 mg/g) than the pristine biochar (BC). The uptake capacity of BCA and BC for CF was found to be pH-dependent. The analysis of the kinetic and isotherm studies indicated that strong chemical-sorption interactions occurred on the surface of BCA. The removal mechanisms of CF onto BCA would include π-π EDA interaction, hydrogen bonding, ion exchange and electrostatic adsorption. In addition, the fixed bed experiments demonstrated that BCA could be a promising and highly effective adsorbent to treat large volume of CF-contaminated wastewater.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Yanan Yan,Lin Li,Huilin Zhang,Fangfang Du,Yating Meng,Shaomin Shuang,Ruibing Wang,Shengmei Song,Chuan Dong
The B,N dual-doped carbon dots (B,N-CDs) for ratiometric fluorescence detection the morin were prepared from sodium tetraborate and polyethyleneimine through the single-step hydrothermal method . The B,N-CDs exhibited the optimum excitation and emission wavelength at 340 nm and 467 nm, respectively. Interestingly, the intensities of emission peak at 467 nm of B,N-CDs reduced meanwhile a new peak emerged at 560 nm with the continuous addition of morin, which revealed the ratio fluorescence characteristic between F 560nm /F 467nm and morin concentration with the linearity range and detection limit of 14.5–32.5 μmol/L and 0.3 μmol/L (S/N = 3), respectively. The interference of common antibiotics and remedies could be ignored when the concentration of morin was detected by the B,N-CDs, which demonstrating the outstanding selectivity. Furthermore, the proposed fluorescence method is used to detect morin in urine with recoveries are 99.8–104.5%. The results of this research indicate the feasibility and practicality of B,N-CDs as an effective fluorescent probe for the determination of morin.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 27
·期 4
·4520-4527
·
IF 2.914
Guo Feng,Zhu Zihan,Zheng Zhangqin,Jin Ying,Di Xiaoxuan,Xu Zhonghao,Guan Hongwei
Rampant use of tetracycline in animal feed is a threat to food security, the environment, and human health because of the risk of drug residues. Therefore, it is necessary to establish a sensitive, efficient, and reliable method for qualitative and quantitative detection of tetracycline. In this paper, we synthesized fluorescent carbon dots (FCDs) by thermal cracking of crab shell waste, and obtained a fluorescence quantum yield of 30%. Characterization of the FCDs by transmission electron microscopy, Fourier-transform infrared spectroscopy, ultraviolet visible absorption spectroscopy, and photoluminescence spectroscopy showed that they were fluorescent and evenly distributed with an average size of approximately 10 nm. We designed a sensitive probe for detecting tetracycline using the fluorescence intensity change of the FCDs. This method is sensitive, inexpensive, and environmentally friendly. The concentration of tetracycline was examined by comparing the fluorescence intensities of the FCDs before and after tetracycline addition. The limit of detection for tetracycline was 0.005 mg/L (signal-to-noise ratio = 3), which is promising for method development.
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ANALYST
·
2019
·Vol. 144
·期 8
·2656-2661
·
IF 4.019
Pengcheng Xing,Di Wu,Jingshuai Chen,Jiming Song,Changjie Mao,Yuanhao Gao,Helin Niu
Recently, the pollution and damage caused by antibiotics in water have aroused serious concerns. In this situation, it is extremely important to develop a highly effective approach to detect antibiotics in water. In this contribution, we built a Cd-MOF material with stable fluorescence properties, using bbi = 1,4-bis(2-methyl-imidazol-1-yl)butane and H2L = 1,2-phenylenediacetic acid as organic ligands and Cd(NO3)2·4H2O as the metal node. The highly selective response of this MOF probe to ceftriaxone sodium (an antibiotic) can reach up to the ppb level in water, along with a fast response time, acid and alkali resistance, and anti-interference ability.
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ENVIRONMENTAL RESEARCH
·
2024
·
IF 7.7
Zhenbin Chen,Haohan Cai,Feng Huang,Zongping Wang,Yiqun Chen,Zizheng Liu,Pengchao Xie
β-lactam antibiotics, extensively used worldwide, pose significant risks to human health and ecological safety due to their accumulation in the environment. Recent studies have demonstrated the efficacy of transition metal-activated sulfite systems, like Fe(Ⅲ)/HSO 3 − , in removing PPCPs from water. However, research on their capability to degrade β-lactam antibiotics remains sparse. This paper evaluates the degradation of 14 types of β-lactam antibiotics in Fe(Ⅲ)/HSO 3 − system and establishes a QSAR model correlating molecular descriptors with degradation rates using the MLR method. Using cefazolin as a case study , this research predicts degradation pathways through NPA charge and Fukui function analysis, corroborated by UPLC-MS product analysis. The investigation further explores the influence of variables such as HSO 3 − dosage, substrate concentration , Fe(Ⅲ) dosage, initial pH and the presence of common seen water matrices including humic acid and bicarbonate on the degradation efficiency. Optimal conditions for cefazolin degradation in Fe(Ⅲ)/HSO 3 − system were determined to be 93.3 μM HSO 3 − , 8.12 μM Fe(Ⅲ) and an initial pH of 3.61, under which the interaction of Fe(Ⅲ) dosage with initial pH was found to significantly affect the degradation efficiency. This study not only provides a novel degradation approach for β-lactam antibiotics but also expands the theoretical application horizon of the Fe(Ⅲ)/HSO 3 − system.
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JOURNAL OF FLUORESCENCE
·
2024
·
IF 2.6
Chen De Xing,Long Yun Fei
The copper nanoclusters (CuNCs) have been garnered significant attention owing to their low cost raw materials, outstanding optical properties, environmental friendliness and good biocompatibility. In this study, copper nanoclusters stabilized by Acid Chromic Blue K (ACBK-CuNCs) were synthesized. The optimal excitation wavelength of the synthesized ACBK-CuNCs is 344 nm and the optimal emission wavelength is 460 nm. Its fluorescence intensity can be retained for more than two weeks, which indicated that the antioxidant capacity of the synthesized ACBK-CuNCs is strong. It was noted that the fluorescence intensities of the synthesized ACBK-CuNCs significantly increased with the decrease of pH. There are good linear correlation between the fluorescence intensity ratio of the system to the fluorescence intensity of the original solution (F/F 0 ) and the pH of the medium. Based on this finding, a method for fluorescence analysis to detect the pH of solution was developed. Additionally, it was discovered that the fluorescence intensity of CuNCs could be quenched efficiently by Berberine hydrochloride (BH), and there is a favorable linear relationship between the change value of fluorescence intensity of CuNCs ((F 0 - F) / F 0 ) and the concentration of BH. This gave rise to the establishment of a fluorescence analysis method for determining the concentration of BH. Simultaneously, visual quantitative detection for BH and pH was achieved based on smartphones and colorimetric analysis software using ACBK-CuNCs as the fluorescent probes. Graphical
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CHEMICAL PAPERS
·
2025
·
IF 2.5
Chen De Xing,Long Yun Fei
In this paper, a novel copper nanoclusters (ARG-CuNCs) has been synthesized by Acid red G stabilized. The optimal excitation wavelength of the synthesized ARG-CuNCs is 330 nm, and a corresponding emission peak is 426 nm. Notably, the fluorescence intensity of ARG-CuNCs could be stablized over six months, and it exhibits minimal variation within the pH range of 2.21–11.58, indicating exceptional stability of the synthesized copper nanoclusters. It was observed that tetracycline (TC) effectively quenches the fluorescence intensity of ARG-CuNCs, and the relative fluorescence intensity change ( Q = F 0 /F) exhibiting a linear relationship with the concentration of TC in the range of 1.0–110.0 µmol/L, and the detection limit (LOD) is 0.33 µmol/L. Thus, a fluorescence-based analytical method for determining TC concentration has been developed based on the relationship of the Q value with the concentration of TC. Furthermore, leveraging a smartphone and colorimetric analysis software, a novel visual quantitative detection method for TC detection has been established based on the image of the mixture solution (TC and ARG-CuNCs) under the 365 nm ultraviolet lamp irradiation, and using ARG-CuNCs as a fluorescence probe. Graphical abstract
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