International Journal of Environmental Research and Public Health
·
2020
·Vol. 17
·期 4
·1324
·
IF 2.849
Yanchang Zhang,Lin Zhao,Yongkui Yang,Peizhe Sun
Biochar (BC)-supported nanoscale zero-valent iron (nZVI-BC) was investigated as a heterogeneous Fenton-like activator to degrade the antibiotic ornidazole (ONZ). The characterization of nZVI-BC indicated that BC could enhance the adsorption of ONZ and reduce the aggregation of nZVI. Thus, nZVI-BC had a higher removal efficiency (80.1%) than nZVI and BC. The effects of parameters such as the nZVI/BC mass ratio, pH, H2O2concentration, nZVI-BC dose, and temperature were systematically investigated, and the removal of ONZ followed a pseudo-second-order kinetic model. Finally, possible pathways of ONZ in the oxidation process were proposed. The removal mechanism included the adsorption of ONZ onto the surface of nZVI-BC, the generation of •OH by the reaction of nZVI with H2O2, and the oxidation of ONZ. Recycling experiments indicated that the nZVI-BC/H2O2system is a promising alternative for the treatment of wastewater containing ONZ.Keywords:nanoparticles;biochar;wastewater treatment;ornidazole
研究领域:
环境科学
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化学工程
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PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2025
·
IF 4.7
Shunxin Xu,Juncai Zhang,Yaru Zhao,Yanqiong Shen,Yichun Qiu,Yuhang Bao,Kui Tang,Yanfang Peng,Yuanqin Zeng,Jinjie Qian,Qipeng Li
R6G@UIO-67 consisted of the rhodamine 6G (R6G) in the nanocages or nano-pores of UIO-67 , which was successfully constructed by the one-pot method under hydrothermal conditions. Whose structure, stability and morphology were characterized by the XRD, TGA and SEM. R6G@UIO-67 exhibited the highly thermal stability up to 550 °C, and emitted the bright yellow light at 580 nm with the quantum yield of 44.66%, which could selectively detect the ornidazole (ODZ) among eight antibiotics. Furthermore, R6G@UIO-67 was associated with commercial green phosphor powder and red phosphor powder, which were encapsulated on the 455 nm blue LED chip, to obtain an exceptional warm white light emitting diode (WLED) device with the CIE coordinates of (0.385, 0.385), correlated color temperature (CCT) of 3951 K, luminous efficiency (LE) of 122.45 lm/w and color render index (CRI) of 93.8.
研究领域:
材料科学
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光学
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分析化学
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2022
·Vol. 415
·期 18
·4221-4232
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IF 4.478
He Ziguo,Liu Jiaxu,Zhang Cheng,Sun Yudie,Chen Qian,Zhang Jian,Liu Shengjun,Yue Caibo,Ye Mingfu,Zhang Kui
Humic acid–based carbon dots (HACDs) have excellent properties and are widely used in environmental detection, bioimaging, and optoelectronic materials. Herein, we investigated the structure–activity relationship between the morphology and optical properties of HACDs, and reported on a novel strategy for metronidazole (MNZ) and ornidazole (ONZ) sensing in multiple real samples. It was found that the average particle size decreased from 3.28 to 2.44 nm, optimal emission wavelength was blue-shifted from 500 to 440 nm, and the quantum yield (QY) improved from 5 to 23% with the temperature increasing from 110 to 400 °C. Under the oxidation of hydrogen peroxide (H 2 O 2 ) and potassium permanganate (KMnO 4 ), the UV–vis spectra of HACD aqueous solution showed time-dependent behavior, and the fluorescence emission of HACDs achieved spectrally tunable multi-color luminescence in the temporal dimension. The surface of HACDs contained a large number of hydroxyl (–OH) and carboxyl (–COOH) fluorophores, resulting in excellent pH sensing. Meanwhile, the synthesized HACDs revealed sensitive response to MNZ and ONZ with the limit of detection (LOD) of 60 nM and 50 nM in aqueous solutions, which had also been successfully applied in various actual samples such as lake water, honey, eggs, and milk with satisfactory results because of the inner filter effect (IFE). Our research is advantageous to enhance the potential applications of HACDs in advanced analytical systems. Graphical abstract
研究领域:
分析化学
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环境科学
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生物医学工程
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高影响因子
RSC Advances
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2021
·Vol. 11
·期 37
·22993-23001
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IF 3.361
Weizhen Wu,Xiaoyi Wu,Miao He,Xiaolin Yuan,Jiaping Lai,Hui Sun
A carbon dot/polyacrylamide (CDs/PAM) composite hydrogel film with stable fluorescence performance was fabricated by merging a hydrogel film and carbon dots (CDs) with blue fluorescence, which were prepared by hydrothermal synthesis using anhydrous citric acid and acrylamide as carbon sources. The obtained CDs/PAM composite hydrogel film exhibited a good fluorescence quenching effect on ornidazole (ONZ), and can be used for the quantitative detection of ONZ. In the ONZ concentration range of 5–60 μM, a good linear relationship between the fluorescence quenching efficiency of the CDs/PAM composite hydrogel film and the concentration of ONZ solution was obtained with a low detection limit of 2.35 μM. In addition, the detection system has good selectivity and strong anti-interference capacity, and can be used in repeated cycles for detection.
研究领域:
材料科学
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分析化学
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药物检测
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PubMed
高影响因子
Journal of Future Foods
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2025
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IF 7.2
Jia-Hui Zhu,Sheng-Nan Lv,Mo-Lin Li,Wei-Kai Zhu,Yu-Shen Liu,Lu-Liang Wang
Ornidazole (ONZ), a widely used nitroimidazole antibiotic, has raised significant environmental and health concerns due to its persistence and potential carcinogenicity. Existing detection methods often suffer from matrix interference and cumbersome procedures. In this study, a novel magnetic covalent organic framework (Fe 3 O 4 @TZ-DMTP) with a core-shell structure was synthesized via in situ hydrothermal growth of 2,4,6-tri(4-aminophenyl)-1,3,5-triazine (TZ) and 2,5-dimethoxy-terephthalaldehyde (DMTP) on magnetic nanoparticles. The composite exhibited high surface area, superparamagnetism and excellent adsorption capacity for ONZ through π-π interactions, hydrogen bonding, and hydrophobic effects. Coupled with HPLC-DAD, a robust magnetic solid-phase extraction (MSPE) method was developed, achieving a wide linear range (0.01-10 µg mL⁻¹) and low detection limit (0.003 µg mL⁻¹). The method demonstrated superior anti-interference capability and reusability (>90% recovery after 7 cycles). Successful application to tap water, lake water, aquaculture water, milk and honey samples confirmed its practicality with recoveries of 80.8-103.2% and RSDs < 13.8%. This work provides a sustainable and efficient strategy for monitoring nitroimidazole residues in complex matrices.
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高影响因子
ELECTROANALYSIS
·
2025
·Vol. 37
·期 7
·e70011
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IF 2.3
Jie Zhou,Qi Lou,Yan Li,Yanjing Zhang,Guanpu Zeng,Rui Lv,Jin Li,Jing Lan,Yaru Li,Zongshan Zhao
The overuse of ornidazole (ODZ) can cause imbalances in thehuman microbiome system and lead to the emergence of antibiotic-resistant bacteria. Therefore, developing sensitive and rapid methods for detecting ODZ has been of concern. In this article, metal organic framework-derived cobalt-supported nitrogen-doped carbon nanocages (Co@CN-CNTs) were prepared for sensitive electrochemical detection of ODZ. Electrodes prepared using Co@CN-CNTs (Co@CN-CNTs/GCE) had good electrochemical current response to ODZ and exhibited a wide detection range for ODZ, from 60 nM to 45 μM, with a low limit of detection (LOD) of 6.7 nM. The sensor showed excellent performance toward detecting ODZ, with recovery rates ranging from 96.36% to 104.00% when detecting tap water, river water and fruit samples. Moreover, the sensor also presented satisfactory repeatability and excellent selectivity towards ODZ by minimizing the risk of false positives or interferences from other compounds. Overall, the Co@CN-CNTs/GCE sensor provided a low cost and rapid method for detection of ODZ in environmental samples.
研究领域:
电化学传感器
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环境监测
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纳米材料
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分析化学
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抗生素检测
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DOI
高影响因子
ENVIRONMENTAL TECHNOLOGY
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2025
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IF 2
Tao Zhao,Minghao Xu,Xuerui Yang,Jean-Marc Chovelon,Lei Zhou
High-valent metal species (HVMS) exhibited exceptional oxidative capabilities and selectivity in advanced oxidation processes (AOPs), making them promising oxidants for environmental remediation. However, their inherent instability has hindered kinetic assessments and limited further applications. This study developed a quantitative structure–activity relationship (QSAR) model for predicting the pseudo-first order rate constants (kobs) of high-valent copper species Cu(III) with typical emerging contaminants (ECs). The optimal model was logkobs = 0.002×PSA – 10.1465 × q(C-)X – 4.5896 × ELUMO – 2.0116. R2adj (0.822), Q2LOO (0.784), and Q2ext (0.951) shown the model’s robust and great predictive ability. Polar surface area (PSA), Hirshfeld charge on carbon atoms (q(C-)X), and the energy of the lowest unoccupied molecular orbital (ELUMO) synergistically controlled the reactivity of Cu(III). A larger PSA was conducive to the diffusion of ECs in aquatic environments. Additionally, Density functional theory (DFT) calculations revealed that a smaller q(C-)X could increase the nucleophilic sites of ECs, thereby enhancing the electrophilic reaction of Cu(III). And a lower ELUMO was beneficial for adjusting the energy gap (EGAP) to enhance the reactivity of ECs. This study filled the gap in the prediction of kobs for Cu(III) and provided a reliable reference for the selective treatment of different ECs by HVMS.
研究领域:
环境科学
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计算化学
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2021
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IF 4.098
Xueqing Guo,Yang Liu,Wenjuan Dong,Qin Hu,Yong Li,Shaomin Shuang,Chuan Dong,Lishuai Cai,Xiaojuan Gong
Azithromycin (AZM) 1 is one of the most widely used antibiotics. AZM abuse is easy to cause great harm to human body, so developing a rapid and sensitive method to detect AZM is of great importance. Herein, 3-aminothiophenol as only reaction precursor, nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) 2 were fabricated by one-step hydrothermal carbonization method. All characteristics demonstrate that N,S-CQDs possess good water solubility, high fluorescence stability and low cytotoxicity. Without being disturbed by amino acids and drugs, the most interesting finding is that AZM can efficiently quench the fluorescence of N,S-CQDs by a synergistic effect of electrostatic interaction and static quenching. A fluorescent probe for the detection of AZM was constructed with high selectivity and good sensitivity, achieving two linear ranges of 2.5–32.3 μM and 37.2–110 μM and a limit of detection of 0.76 µM. The proposed fluorescent method was used for the detection of AZM in cells with fulfilling results. More importantly, the fluorescent probe was successfully used to the detection of AZM in tablets and human urine with recovery rate and relative standard deviations of 98.2–104.8% and 0.04–3.46%, respectively, which was confirmed by the standard method of HPLC-UV. This finding illustrates the usefulness and feasibility of N,S-CQDs as an effective fluorescent probe for the detection of AZM in tablets and human urine, which is helpful for supervising and guiding pharmacy.
研究领域:
药物分析
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荧光材料
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生物医学工程
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 4
·1-11
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IF 6.232
Wang Qianqian,Li Gaigai,Wang Chun,Wu Qiuhua,Wang Zhi
A layered porous organic framework (L-POF) with high surface area and porous volume was used as a novel adsorbent for adsorption of chlorophenols (CPs). The L-POF showed much higher adsorption capacity for four CPs (2-CP, 3-CP, 2,3-CP, 2,4-CP) compared with corresponding amorphous POF and some commercial adsorbents. Then, an L-POF-based solid-phase extraction method combined with high-performance liquid chromatography for analyzing CPs at the wavelength of 280 nm in water and honey samples was established. Under the optimum conditions, four CPs exhibited good linearity in the range 0.10–80.0 ng mL −1 for water and 2–400 ng g −1 for honey samples with determination coefficient r 2 > 0.996. The method has low limits of detection of 0.03–0.10 ng mL −1 for water and 0.5–1.0 ng g −1 for honey samples. The method presented satisfactory precision and accuracy with relative standard deviations ≤ 7.8% and recoveries of 80–115%. High enrichment factors of 123–190 for water and 63–97 for honey were obtained. The validated method was successfully used to determine CPs in water and honey samples. The L-POF also displayed prominent adsorption performance for many other dyes and organic contaminants. This suggests that it can be an ideal candidate as adsorbent for wide application in separation and analysis.
Graphical Abstract
研究领域:
分析化学
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环境科学
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Guodong Ren,Xiaoyu Hou,Yu Kang,Rong Zhang,Min Zhang,Wen Liu,Lihong Li,Shuangyan Wei,Haojiang Wang,Bin Wang,Haipeng Diao
Herein, nitrogen-doped carbon dots (N-CDs) emitting blue fluorescence were prepared using L-tartaric acid and triethylenetetramine through a simple and quick microwave-assisted method. The synthesized N-CDs displayed excitation-dependent fluorescence behavior, and their maximum excitation and emission wavelengths were 350 and 425 nm, respectively. The obtained N-CDs, which featured excellent fluorescence properties with a high fluorescence quantum yield of 31%, were applied to detect metronidazole (MNZ), which can effectively quench the fluorescence intensity of N-CDs due to the inner filter effect. This phenomenon was used as basis to develop a label-free fluorescent method for rapid MNZ determination, with the limit of detection of 0.22 μM and corresponding linear range of 0.5–22 μM. Hence, we had established a fluorescence method for MNZ detection and applied it to detect MNZ in real samples with satisfactory results. Finally, N-CDs with superior biocompatibility were applied for cell imaging and MNZ detection by the changes in fluorescence intensity.
研究领域:
材料科学
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分析化学
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生物医学工程
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PubMed
高影响因子
FOOD CHEMISTRY
·
2020
·
IF 6.306
Qianqian Wang,Weihua Liu,Lin Hao,Chun Wang,Qiuhua Wu,Zhi Wang
A magnetic porous organic framework (M-POF) was rationally designed and served as a sorbent for magnetic solid-phase extraction of six nitroimidazoles from chicken meat prior to their assay by high-performance liquid chromatography with diode array detection. The M-POF exhibited good magnetic responsiveness and outstanding affinity to nitroimidazoles with large adsorption capacity up to 36 mg g −1 . Under optimal conditions, the developed method offered good linearity ( r greater than 0.992) in the range of 1.5–100.0 ng g −1 , low limits of detection (S/N = 3) of 0.5–0.8 ng g −1 , low limits of quantification of 1.5–2.5 ng g −1 and high enrichment factors of 80–175 for the nitroimidazoles. The method was successfully applied to analyze nitroimidazoles in chicken meat. The recoveries were 80.2–118% with relative standard deviations lower than 12%. The adsorption mechanism was further explored and the results showed that the M-POF exhibited adsorption potential for compounds with strong polar interactions.
研究领域:
分析化学
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食品科学
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材料科学
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PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2016
·
IF 4.712
Na Xu,Hong-Wei Li,Yuqing Wu
A novel one-step hydrothermal synthesis of highly fluorescent platinum nanoclusters protected by polyethylenimine (Pt-NCs@PEI) is described. The products are characterized well by UV–vis absorption, fluorescence spectra , X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM) imaging. The Pt-NCs@PEI possess high quantum yield at 28%, which is the relatively high one among the reported Pt-NCs; especially, the synthesis is in one-step and the reaction time is much shorter (<1 h) than the related methods. In addition, the Pt-NCs@PEI have large Stocks-shift (∼150 nm), high tolerability to the extreme pH and high ionic strengths , and excellent photo-stability under UV–vis irradiation, lay the foundation for the practical bio-applications. Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25–300 μM and a low detection limit of 0.1 μM. Furthermore, the related investigation on response mechanism will be helpful to design and synthesize new metal nanoclusters as fluorescent probe to detect the trace amount of harmful medicine residuum as nitroimidazoles in human body.
研究领域:
分析化学
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纳米材料科学
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生物医学工程
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）