Analytical Methods
·
2014
·Vol. 6
·期 13
·4643-4651
·
IF 1.938
Xingping Lu,Yinjian Ye,Yingzhen Xie,Yonghai Song,Shouhui Chen,Ping Li,Lili Chen,Li Wang
A novel nonenzymatic glucose sensor was prepared based on a Cu coralloid granule/polyaniline (PANI)/reduced graphene oxide (rGO) nanocomposite modified glassy carbon electrode (GCE). The PANI nanowire array/rGO nanocomposite was synthesized by using an in situ chemical oxidative polymerization method, and then was cast onto a GCE surface. Cu coralloid granules were constructed on PANI/rGO/GCE by constant potential deposition. The Cu/PANI/rGO nanocomposite was characterized by scanning electron microscopy, X-ray energy dispersive spectroscopy, X-ray powder diffraction and Fourier transform infrared spectroscopy. The electrochemical and electrocatalytic behaviors of the Cu/PANI/rGO/GCE towards glucose oxidation were evaluated by cyclic voltammograms, electrochemical impedance spectroscopy, chronoamperometry and amperometric method. The amperometric response of Cu/PANI/rGO/GCE showed high catalytic activity towards the oxidation of glucose with a wide linear range of 0.01–9.66 mM, high sensitivity of 603.59 μA cm−2 mM−1 and low detection limit of 1.34 μM (S/N = 3).
研究领域:
电化学
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纳米技术
·
材料科学
·
分析化学
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DOI
高影响因子
TALANTA
·
2017
·
IF 4.162
Zhonghua Xue,Hui Wang,Honghong Rao,Nan He,Xiaofen Wang,Xiuhui Liu,Xiaoquan Lu
Indicator displacement assay plays a fundamental role in the development of chemosensors . We explored here an ingenious yet effective strategy for amperometric assay of electrochemically inactive sarcosine based on an indicator displacement principle, in which 1,2-naphthoquinone-4-sulphonic acid sodium salt (NQS) was proposed as the receptor and the electroactive Ru(NH 3 ) 6 3+ cations used as an indicator. Due to the stronger binding affinity of the NQS toward sarcosine than toward Ru(NH 3 ) 6 3+ , the developed amperometric indicator displacement assay (A-IDA) exhibits high selectivity and excellent sensitivity toward sarcosine determination as well as with a lower detection limit (30.00 nM, S/N =3).
研究领域:
分析化学
·
生物医学工程
·
电化学传感器
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DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2013
·
IF 2.672
Yinfeng Li,Lina Zou,Ge Song,Kunjing Li,Baoxian Ye
The electro-polymerization of l -Theanine was investigated for the first time on glassy carbon electrode and the polymeric conditions and mechanism were discussed in detail. Hereafter, a simple and sensitive electrochemical sensor based on the poly( l -Theanine) film was established for sophoridine sensing. The electrode process of sophoridine was then studied by cyclic voltammetry and its determination was achieved by amperometry . The results revealed that the poly( l -Theanine) membrane effectively decreased the oxidation potential of sophoridine and greatly increased its response current. And this sensor, fabricated easily and simply as well as very easy surface update, showed good response for sophoridine with a wide linear range from 1.0 × 10 −6 to 1.4 × 10 −4 mol L −1 and a low detection limit of 5 × 10 −7 mol L −1 . The application of proposed method in analysis of real sample was also evaluated with good performance. This work promoted the potential applications of amino acid materials in electrochemical sensors.
研究领域:
分析化学
·
电化学
·
药物分析
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生物传感
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分子诊断
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药物代谢
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DOI
高影响因子
Scientific African
·
2023
·
IF 2.9
Yideneku Feye,Abebe Diro,Getu Sisay,Shimeles Addisu Kitte
This study was aimed to investigate the selective electrochemical determination for dopamine based on thioglyolic acid-modified gold electrode. Negatively charged Au electrode surface was created by making Thioglycolic acid film through thiol functional group. Greater oxidation current and less overpotential was observed for the oxidation of dopamine in phosphate buffer solution of pH 8.0 at thioglyolic acid-modified gold electrode than bare Au electrode due to the electrostatic attraction between the negatively charged thioglyolic acid-modified gold electrode surface and positively charged dopamine. The electrochemical behavior of dopamine at the thioglyolic acid-modified gold electrode showed a linear response from 0.05 to 100.0 µM and the limit of detection is 0.01 µM using chronoamperommetry. The proposed thioglyolic acid-modified gold electrode shows good repeatability and promising application in dopamine hydrochloride injection sample.
研究领域:
分析化学
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电化学
·
生物传感器
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DOI
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 10
·1-11
·
IF 5.3
Li Ningzhen,Zhang Zhenteng,Tian Tingting,Sun Luyu,Xu Lixiao,Wang Jiasheng,Hui Ni
A cortisol biosensor was developed based on double-conducting polymer nanowires, which exhibits excellent conductivity, resistance to biological contamination, and outstanding sensing performance. The biosensor employs dual-mode electrochemical techniques, namely, differential pulse voltammetry (DPV) and chronoamperometry (CA), for the sensitive and low fouling detection of the glucocorticoid hormone cortisol. Experimental results demonstrated that the linear detection range of the biosensor in DPV mode was 1.0 × 10 −14 –1.0 × 10 −8 M, with a detection limit of 0.131 × 10 −14 M. In CA mode, the biosensor exhibited a detection range of 1.0 × 10 −13 –1.0 × 10 −7 M and a detection limit of 0.313 × 10 −13 M. The biosensor was successfully utilized for the rapid detection of cortisol in human saliva. The combination of a high-specificity cortisol aptamer and functionalized double-conducting polymer nanowires ensured the exceptional specificity and sensitivity of the biosensor in detecting real biological samples. Graphical Abstract
研究领域:
生物传感器技术
·
分析化学
·
医学诊断
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2014
·
IF 2.871
Duo Xu,Liqiang Luo,Yaping Ding,Lin Jiang,Yuting Zhang,Xiaoqian Ouyang,Bingdi Liu
We have developed a nonenzymatic electrochemical sensor based on a carbon paste electrode modified with electrospun LaMnO 3 fibers for fructose determination. LaMnO 3 fibers, a kind of perovskite-type oxide, were prepared by electrospinning and subsequent calcination process. The morphology and structure of LaMnO 3 fibers were characterized by scanning electron microscope, X-ray diffraction and Fourier Transform Infrared spectrum. The electrochemical response of the proposed sensor was evaluated by cyclic voltammetry and amperometry. Under optimal conditions, the linear response for fructose determination was obtained in the range of 0.4–100 μM, with a low detection limit of 63 nM ( S / N = 3).
研究领域:
电化学
·
材料科学
·
分析化学
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产品关联
DOI
高影响因子
Nanoscience and Nanotechnology Letters
·
2019
·Vol. 11
·期 8
·1139-1144
·
IF 0
Gu Mengqiao,Liu Jiali,Li Delei,Wang Min,Chi Kuanneng,Zhang Xi,Deng Yan,Ma Yuchan,Hu Rong,Yang Yunhui
In this paper, a signal-off aptasensor was constructed based on the specificity of OTA and OTA aptamer (DNA2), it can detect the small molecule ochratoxin A (OTA). DNA1 chain with mercapto modified at 3′-end was firstly immobilized on gold electrode, which cross-fertilize with
DNA 2 to form double strands. 30 thymine T modified at the end of DNA2 were used as templates to synthesize Cu NCs which is peroxidase mimics and can catalyze hydrogen peroxide. Presence of OTA, it specifically binds to DNA2, which made DNA2 dissociated, and so did Cu NCs. The more OTA in
solution, the more the aptamers and Cu NCs dissociated from the gold electrode, the less copper nanoclusters remained on the electrode, and the smaller the current response value of the electrode measured by chronoamperometry. Thus, the quantitative determination of OTA can be achieved. This
aptasensor provides a simple and fast technique for OTA detection in red wine samples.
研究领域:
分析化学
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食品安全
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纳米技术
·
生物传感器
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DOI
ANALYTICAL LETTERS
·
2014
·
IF 1.019
Duo Xu,Shuqing Gu,Yaping Ding,Bijun Wang
Nickel doped cobalt(II, III) composite nanofibers were prepared by an electrospinning and sequential calcination process, and characterized by scanning electron microscopy, energy dispersive spectrometry, and X-ray diffraction. An electrospun nickel doped cobalt(II, III) modified carbon paste electrode was used for maltose determination using cyclic voltammetry and amperometry. Under the optimized conditions, a linear response was obtained between 0.2 and 100.0 µM, with a low detection limit of 32.5 nM.
研究领域:
材料科学
·
电化学
·
纳米技术
·
分析化学
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产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2016
·Vol. 408
·期 21
·5819-5827
·
IF 3.125
Zheng Qiqi,Yu Yonghua,Fan Kai,Ji Feng,Wu Jian,Ying Yibin
A nano-silver electrode immobilizing acetylcholinesterase (AChE) for the detection of organophosphorus (OPPs) pesticides is reported. Scanning electron microscopy (SEM) was used to characterize the surface structure of two kinds of electrodes fabricated with different sizes of silver powders and the interface between chitosan layer and nano-silver powder layer. Cyclic voltammetry was carried out to characterize the response of silver/chitosan electrode in the absence and in the presence of thiocholine (TCh). It was also used to evaluate the insulativity of the chitosan layer. An amperometric method was performed to measure the response of the electrode to TCh, which is the product of the enzymatic reaction for detecting organophosphorus pesticides indirectly. Although there are many kinds of nanoparticles, silver was chosen for its internal advantage in detecting TCh at low potential without further modification. The result shows nano-silver powder has better performance than usual silver powder, and the limit of detection of paraoxon is 4 ppb under optimized conditions. One percent (w/v) chitosan solution was used as binder for the immobilization of nano-silver powder and AChE, which made it possible for independent electrode fabrication at room temperature, whereas 3% (w/v) chitosan solution was used as insulating compound for controlling the electrode area. Unlike traditional organic insulating ink, chitosan is safe and environmentally friendly, and it is used as insulating material for the first time. The flexible nano-silver/AChE/chitosan electrode was evaluated in Chinese chives and cabbage , and the recoveries of standard addition were 105.11 and 96.41%, respectively. Owing to the antibacterial property of nano-silver and the biocompatibility, safety, and biodegradability of chitosan, the proposed method is safe, facile, environmentally friendly, and has great potential in organophosphorus pesticide detection for food safety.
Current response of nano-silver electrode ( a ) and silver electrode ( b ) to thiocholine in 0.02 M PBS + KCl at 0.15 V; addition of thiocholine (0.09 mM) every 50 s (↓); inset: calibration curve of nano-silver (▲) and silver (◆) electrode
研究领域:
环境科学
·
分析化学
·
食品安全
·
电化学
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产品关联
DOI
PubMed
高影响因子
Metals
·
2025
·Vol. 15
·期 9
·936
·
IF 2.5
Xiangqing Liu,Chenyu Li,Jie Yu,Ruiqi Liu,Min Shang,Xiaolin Su,Jinye Yao,Haitao Ma
This study investigates the synergistic effects of single- and binary-additive systems on the morphology and nucleation mechanism of Sn-Pb alloy electrodeposited coatings. Scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), linear sweep voltammetry (LSV), electrochemical impedance spectroscopy (EIS), and chronoamperometry were applied in order to obtain more information on the action mechanisms of single-additive systems (cinnamaldehyde, PEG-2000, gelatin, vanillin) and binary ones (0.1 g/L cinnamaldehyde + 0.2 g/L PEG-2000) in Sn-Pb electroplating. Results showed that the use of binary-additive systems based on cinnamaldehyde and PEG-2000 significantly improved coating quality, leading to a smooth and uniform surface, dense grains, and a near-eutectic composition (Sn 63.10 wt.%, Pb 36.90 wt.%). This was because the composite additive, through synergistic effects, exhibited the highest cathodic polarization and the largest charge transfer resistance (189.20 Ω cm2), thus inhibiting the electrodeposition process of Sn2+and Pb2+. Chronoamperometry revealed that, unlike single additives (PEG-2000 or cinnamaldehyde), the binary-additive system promoted a transition of nucleation mode to instantaneous nucleation, accompanied by a decrease in the peak current and an extension of the corresponding time. This study provides a theoretical basis and experimental support for understanding the nucleation mode of Sn-Pb electroplating, as well as optimizing the synergistic mechanism of additives.
研究领域:
材料科学
·
电化学
·
表面工程
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DOI
高影响因子
IONICS
·
2023
·Vol. 30
·期 2
·1089-1100
·
IF 2.8
Zhao Jifan,Lu Zhenyong,Wang Yue,Mário Baptista José Laurindo,Wang Shaoyan
Cellulose, which is one of the main components of wood biomass, was carbonized and activated by KOH to prepare a hierarchical porous carbon. This biomass derived carbon was successfully utilized as an effective sensor’s material for simultaneously determine hydroquinone (HQ) and catechol (CC) through cyclic voltammetry and amperometry techniques. The resulting sensor exhibited wide linear ranges for HQ (0.5–3000 μmol/L) and CC (1–3000 μmol/L), with the detection limits of HQ (0.47 μmol/L) and CC (0.4 μmol/L) by amperometry technique, respectively. In addition, the prepared sensor also possesses good performances including specific selectivity, long lifetime and good applicability. The practical application in domestic lake water samples with satisfied recoveries implies the proposed sensor is promising. These results demonstrate that cellulose containing biomass have potential as an effective precursor of porous carbon materials and are applicable on various electrochemical sensors.
研究领域:
电化学
·
材料科学
·
环境监测
·
分析化学
·
传感器技术
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2013
·
IF 4.612
Xinchun Li,Zuanguang Chen,Jianbin Pan,Fan Yang,Yinbao Li,Meicun Yao
In this work, we describe a novel electrochemical detection method, differential pulsed amperometry (DPA) on microchip capillary electrophoresis (MCE). In a pulse period, a sequential two-step sampling is executed at two different potentials ( E 1 and E 2 ). Differential current signal of the duplex sampling events is recorded that functions as time domain. The performance of this detection scheme was evaluated by separating and detecting three model analytes including tyramine (Tym), tryptophan (Trp), and p -aminobenzoic acid (PABA). Multiple parameters that would affect electrochemical response and peak shape, such as sampling potential, sampling time, and electrode cleaning time, were investigated. This pulse technique exhibits better sensitivity over constant potential amperometry (CPA), nearly equal to triple pulsed amperometry (TPA). More importantly, DPA can generate more stable baseline than TPA, primarily due to the background subtraction through the two-step sampling, which is beneficial to further improve analytical sensitivity. In the optimal condition, the limits of detection for Tym, Trp and PABA, were down to 0.27 μM, 0.32 μM and 1.1 μM, respectively. DPA detection opens up a new avenue for microchip electrochemistry, and can be virtually extended to other fluid analysis techniques.
研究领域:
分析化学
·
电化学
·
微流控
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）