DESALINATION
·
2010
·
IF 2.034
Zhenghua Zhang,Quanfu An,Tao Liu,Yong Zhou,Jinwen Qian,Congjie Gao
Polysulfone ultrafiltration membranes were prepared via the wet phase-inversion process with the same coagulation bath . Three different kinds of systems including polysulfone (PSF)/N, N-Dimethylacetamide (DMAC)/poly(vinyl pyrrolidone) (PVP), PSF/DMAC/Ethanol ternary systems and PSF/DMAC/Ethanol/PVP quaternary system were used as casting solutions . The zero shear viscosity of the casting solutions was measured and the phase-inversion process was monitored by the light transmittance apparatus. The surface and cross-section morphology of the corresponding membranes were characterized by SEM. The water flux and the anti-pressure stability of the membranes were performed in the permeation experiment. The pore size and porosity of the fresh and pressurized membranes were calculated. These experimental results suggest that the PSF ultrafiltration membrane of a density gradient structure prepared from the quaternary system by using PVP and ethanol together in PSF/DMAC/Ethanol/PVP solution with the respective amounts of 3.05 wt.%, 15.5 wt.%, has a good anti-pressure stability and a relatively high water flux (only changed from 162 L/m 2 h to 155 L/m 2 h ) even by continuous operation (0.5 MPa) for 200 min, which is valuable as the sub-supporting membrane of composite membranes.
研究领域:
材料科学
·
膜技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Caide Fan,Jin Yang,Meili Rui,Jianming Yang,Tengyan Shi,Jun Shen,Bin Zhou,Chen Liu,Jie Zhu,Ai Du
Silica-based aerogels are widely regarded as promising sound-absorbing materials due to their low density and high specific surface area. However, their hard surface and small pores hinder sound wave penetration, resulting in a relatively poor sound absorption performance. To overcome this limitation, our study employs melamine foam (MF) as a scaffold to construct a gradient aerogel composite acoustic absorber. This innovative design significantly leads to a low average density (31.3–117.4 mg/cm3) and large density gradient up to 13.7 mg/cm4 (approximately 2.7 times difference compared with the lowest density), and its sound absorption properties are greatly improved, achieving an average absorption coefficient of 87% over the entire frequency band and 95% above 2000 Hz for 30 mm samples. In addition, the best noise reduction coefficient can reach 0.59. For demonstration, simulations further reveal the role of the pore size in enhancing sound absorption. The large pores in the foam skeleton facilitate the coupling of sound waves into the structure, while the small pores in the aerogel effectively block sound wave transmission, providing additional pathways for acoustic energy dissipation. Moreover, the incorporation of aerogel significantly enhances the foam’s mechanical properties. In terms of thermal insulation, the presence of aerogel markedly improves the foam’s insulating performance. This gradient design not only expands the potential applications of aerogels in sound absorption and thermal insulation but also provides a novel approach for the development of advanced acoustic materials.
研究领域:
材料科学
·
声学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 44
·25875-25879
·
IF 3.049
Jie Lu,Ye Pan,Qifeng Zhong,Bing Liu
A simple method to create guided cellular orientation is illustrated by assembling fibroblasts on the dorsal side of M. menelaus wings. Moreover, by inserting the wing into tendon fibroblasts suspension at a tilt angle, guided cellular orientation concurrently with the cell density gradient is formed on the butterfly wings.
研究领域:
细胞生物学
·
组织工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2022
·
IF 8.008
Siyuan Jing,Yu Huang,Yinjuan Chen,Xueqing He,Zhong Chen,Xingyu Lu,Minghuo Wu,Thomas C. Wanger
Nano-/microplastics (NMPs, particle diameter < 5 mm) are widespread emerging pollutants causing diverse impacts on organisms due to their sizes, shapes, and chemical properties. Despite the fast increase in NMP research, an effective method to separate and identify NMP types from environmental samples is still lacking. Here, we developed a simple and effective approach for the non-destructive extraction and separation of various types of NMPs from environmental samples by density gradient ultracentrifugation (DGU). For the first time, DGU was capable to separate various NMPs from the complex matrix with high selectivity (100%), purity (93%), and applicability. Through a gradually changing density of the density gradient medium by changing the concentrations or volumes of CsCl/water solution (from 0.00065 to 0.01989 g cm–3 mm–1), various NMPs (with particle sizes as little as 50 nm) could be extracted and separated from soil samples with high recovery (78.5–96.0%). We confirmed the effectiveness and compatibility of DGU through a correct identification of all types of NMPs separated from artificial soil samples with Raman spectroscopy, simultaneous thermal analysis (STA), and pyrolysis–gas chromatography–mass spectrometry (Py–GC–MS). DGU is compatible with all analytical processes compared to other existing methods with much less sample pretreatment time (0.5 h). Overall, DGU is an effective and cheap method (2.2 USD/sample) to separate NMPs from environmental samples such as soil and water and, hence, can facilitate research on NMPs related to terrestrial and marine environments as well as human health.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2014
·
IF 4.287
Jindan Wu,Zhengwei Mao,Lulu Han,Yizhi Zhao,Jiabin Xi,Changyou Gao
The migration of vascular smooth muscle cells (VSMCs) is an important process in many physiological events. It is of paramount importance to control the migration rate and direction of VSMCs by biomaterials. In this paper, a density gradient of basic fibroblast growth factor (bFGF) was fabricated using an injection method and the bio-conjugation between heparin and bFGF. The density of bFGF gradually increased with a slope of 17 ng/cm 2 /mm. Adhesion and migration of VSMCs were studied on the bFGF gradient. The VSMCs exhibited preferential orientation and an enhanced directional migration behavior on the gradient surface. Up to 70% cells migrated towards the region with a higher density of bFGF on the gradient. However, the bFGF gradient had no effect on the cell migration rate.
研究领域:
生物材料
·
细胞生物学
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
NATURE MATERIALS
·
2019
·Vol. 18
·期 9
·936-941
·
IF 38.887
Sun Qiangqiang,Wang Dehui,Li Yanan,Zhang Jiahui,Ye Shuji,Cui Jiaxi,Chen Longquan,Wang Zuankai,Butt Hans-Jürgen,Vollmer Doris,Deng Xu
The directed, long-range and self-propelled transport of droplets on solid surfaces is crucial for many applications from water harvesting to bio-analysis 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 . Typically, preferential transport is achieved by topographic or chemical modulation of surface wetting gradients that break the asymmetric contact line and overcome the resistance force to move droplets along a particular direction 10 , 11 , 12 , 13 , 14 , 15 , 16 . Nonetheless, despite extensive progress, directional droplet transport is limited to low transport velocity or short transport distance. Here we report the high-velocity and ultralong transport of droplets elicited by surface charge density gradients printed on diverse substrates. We leverage the facile water droplet printing on superamphiphobic surfaces to create rewritable surface charge density gradients that stimulate droplet propulsion under ambient conditions 17 and without the need for additional energy input. Our strategy provides a platform for programming the transport of droplets on flat, flexible and vertical surfaces that may be valuable for applications requiring a controlled movement of droplets 17 , 18 , 19 .
研究领域:
材料科学
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流体力学
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微流控
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表面工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-8
·
IF 16.6
Peng Weichao,Yan Shuaihu,Zhou Ke,Wu Hai-Chen,Liu Lei,Zhao Yuliang
The hollow and tubular structure of single-walled carbon nanotubes (SWCNTs) makes them ideal candidates for making nanopores. However, the heterogeneity of SWCNTs hinders the fabrication of robust and reproducible carbon-based nanopore sensors. Here we develop a modified density gradient ultracentrifugation approach to separate ultrashort (≈5-10 nm) SWCNTs with a narrow conductance range and construct high-resolution nanopore sensors with those tubes inserted in lipid bilayers. By conducting ionic current recordings and fluorescent imaging of Ca 2+ flux through different nanopores, we prove that the ion mobilities in SWCNT nanopores are 3-5 times higher than the bulk mobility. Furthermore, we employ SWCNT nanopores to discriminate homologue or isomeric proteinogenic amino acids, which are challenging tasks for other nanopore sensors. These successes, coupled with the building of SWCNT nanopore arrays, may constitute a crucial part of the recently burgeoning protein sequencing technologies.
研究领域:
纳米技术
·
生物化学
·
分子生物学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2024
·
IF 7
Shijie Liu,Lijun Zhao,Miaoyun Li,Jong-Hoon Lee,Yaodi Zhu,Yanxia Liu,Lingxia Sun,Yangyang Ma,Qiancheng Tu,Gaiming Zhao,Dong Liang
There is an urgent need for quick, sensitive, thorough, and low-cost preliminary screening and rapid identification method for probiotic resource development. Here, we constructed a culture-free, accurate and sensitive “separation-enrichment-detection” rapid evaluation and identification method of probiotics in fermented food based on Ramanomes technology, and established a Ramanome reference of lactic acid bacteria and yeasts by AgNPs nanostructure array (AgNPs NSA) chips with uniform “hot spots” and high signal enhancement ability as SERS substrates. Systematic cluster analysis could clearly distinguish among different genera of lactic acid bacteria and yeast, and could indicate the affinity and difference between lactic acid bacteria of the same genus and yeast of the same genus. The recognition accuracy of convolutive neural networks was 100 %, and the recognition sensitivity was less than 10 CFU/mL. We constructed a probiotic isolation and enrichment method by velocity gradient centrifugation and density gradient differential centrifugation, and the average recoveries of lactobacilli and yeasts were greater than 98 % in the practical application, and the accuracy of the verified classification was 100 %. In conclusion, this study has established a preliminary screening strategy of “screening before cultivating” for lactic acid bacteria and yeasts, which breaks through the principle limitation of the current traditional paradigm of “cultivating before screening”. It can greatly improve the preliminary screening rate of probiotics in fermented foods, and provide a good technical support for the mining of probiotic resources from environmental or complex matrix samples.
研究领域:
食品科学
·
微生物学
·
生物技术
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Frontiers of Chemical Science and Engineering
·
2022
·Vol. 16
·期 12
·1735-1742
·
IF 4.803
Yu Guojia,Jin Dongyu,Li Xinyu,Zhang Fan,Tian Shichao,Qu Yixin,Zhou Zhiyong,Ren Zhongqi
A nitrogen-containing ionic liquid was synthesized using an aromatic nitrogen-containing heterocyclic and an amino acid, and applied to the extractive desulfurization process to remove benzothiophene, dibenzothiophene, and 4,6-dimethyldibenzothiphene from a model fuel oil. Chemical characterizations and simulation using Gaussian 09 software confirmed the rationality of an ionic liquid structure. Classification of non-covalent interactions between the ionic liquid and the three sulfur-containing contaminants was studied by reduced density gradient analysis. The viscosity of the ionic liquid was adjusted by addition of polyethylene glycol. Under extraction conditions of the volume of ionic liquid to oil as 1:1 and temperature as room temperature, the desulfurization selectivity of ionic liquid followed the order of 4,6-dimethyldibenzothiphene (15 min) < benzothiophene (15 min) ≈ dibenzothiophene (10 min). Addition of p -xylene and cyclohexene to the fuel oil had little effect. The extractant remained stable and effective after multiple regeneration cycles.
研究领域:
化学
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2021
·
IF 4.076
Yuntian Xiao,Ling Zhou,Hongxun Hao,Ying Bao,Qiuxiang Yin,Chuang Xie
Propylthiouracil (PTU) is a clinically preferred drug to treat hyperthyroidism effectively. The sustained release of PTU is necessary because of the shortcomings of rapid release and hepatotoxicity. In this study, cocrystals of PTU with nutritional coformers were screened, and four new cocrystals of PTU with cinnamic acid (CA), gentistic acid (GA), ellagic acid (EA), and kaempferol (KA) were discovered. The cocrystals were characterized by single-crystal and powder X-ray diffraction, differential scanning calorimetry, thermogravimetric analysis, and scanning electron microscopy. The Hirshfeld surface analysis and reduced density gradient analysis reveal that the weak van der Waals interactions play an essential role in the crystal packing. The stability test indicates that all four cocrystals show excellent stability under accelerated storage conditions (40 °C and 75% RH) over 12 weeks. Moreover, PTU-CA, PTU-EA, and PTU-KA cocrystals all exhibit decreased solubility and decelerated intrinsic dissolution rate (IDR). Among them, the PTU-KA cocrystal shows the best performance. Specifically, the solubility decrease is up to 77.32% in pH 1.2 buffer and 85.15% in pH 6.8 buffer, and the lowest IDR is 12.0% and 20.8% of that of PTU in pH 1.2 and 6.8 buffers. According to the calculation result, the sustained-release effect could be attributed to the enhanced lattice energies and hydrophobic interaction. This work may be useful to design a sustained-release system via cocrystallization of APIs that have significant hepatotoxicity.
研究领域:
药学
·
材料科学
·
药物递送系统
·
晶体学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL RESEARCH
·
2022
·
IF 8.431
Qiulin Li,Simin Zhu,Feng Chen,Chunxian Guo
Functional groups modified metal-organic frameworks (MOFs) was synthesized via a pre-tailor method and served as an adsorbent for perfluorooctanoic acid (PFOA) removal. The material was characterized using Fourier transform infrared spectroscopy , scanning electron microscopy, X-ray diffraction and N 2 sorption-desorption. Monte Carlo simulation and molecular dynamics are derived to predict the possible molecular packing and adsorption mechanism. The Hirshfeld surface with reduced density gradient analysis demonstrates that PFOA is adsorbed on MOF-X mainly affected by van der Waals interactions and steric effects. Adsorption kinetics and isotherms were investigated on the basis of a static experiment. The pseudo-second-order kinetic model and Langmuir isotherm were fitted well to characterize adsorption process. Hereinto, amino-modified MOFs reached the highest adsorption efficiency and the maximum capacity was 185.6 mg/g. Combing the experimental data with theoretical simulation, results indicated that functional group modification is an effective approach to alter the crystal structure and then affect the adsorptive properties of MOFs.
研究领域:
材料科学
·
环境化学
·
理论化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2021
·
IF 10.618
Min Hou,Liyang Shi,Yancen Zhou,Jiao Wang,Jiali Jiang,Jianhui Jiang,Jianjun He
Although suspension array technology (SAT), which uses encoded microspheres , provides high-quality results with versatile applicability for information-intensive bioanalytic applications, current encoding strategies limit the number of codes that can be distinguished. In this paper, we introduce density-encoded hydrogel microcarriers (DMs), which employ the intrinsic density property of biomaterials as a high-capacity coding dimension. Two hydrogel monomers were employed at different ratios to synthesize microgels with distinctive densities. DMs not only can be simultaneously decoded and separated using density gradient centrifugation, but also are compatible with flow cytometry detection. The size and color of DMs have been used as extra coding parameters, to construct an 8 × 2 × 4 (density × size × color) three-dimensionally encoded hydrogel microcarrier library. With aptamer-functionalized DMs (ADMs), we developed a 4-plex protein quantification method for the label-free detection of plasma biomarkers with sub-nanomolar detection limits and good linearities. Moreover, ADMs can be used for label-free naked-eye detection of tumor-derived exosomes. We believe that the simplicity and functionality of DMs will advance the field of suspension arrays and inspire the development of DM-based diagnostic applications.
研究领域:
生物技术
·
生物分析化学
·
诊断医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）