Materials
·
2017
·Vol. 10
·期 2
·149
·
IF 2.654
Liang Wang,Da-Gang Guo
A UV-curable poly(butyl fumarate) (PBF)/poly(propylene fumarate)-diacrylate (PPF-DA) hybrid material with good performance for LED encapsulation is introduced in the paper. They have been prepared by radical polymerization using PBF and PPF-DA macromers with a UV curing system. PBF and PPF-DA were characterized by Fourier-transform infrared (FT-IR) and H-nuclear magnetic resonance (1H NMR). The thermal behavior, optical and mechanical properties of the material were examined by thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), ultraviolet-visible spectroscopy (UV–vis), and a material testing system mechanical testing machine, respectively. The results indicated that the hybrid material has a suitable refractive index (n= 1.537) and high transmittance (99.64% in visible range) before/after thermal aging. With the increasing of the double bond ratio from 0.5 to 2, the water absorption ratios of the prepared encapsulation material were 1.22%, 1.87% and 2.88%, respectively. The mechanical property experiments showed that bonding strength was in the range of 1.86–3.40 MPa, tensile-shear strength ranged from 0.84 MPa to 1.57 MPa, and compression strength was in the range of 5.10–27.65 MPa. The cured PBF/PPF-DA hybrid material can be used as a light-emitting diode (LED) encapsulant, owing to its suitable refractive index, high transparency, excellent thermal stability, lower water absorption, and good mechanical properties.Keywords:poly(butyl fumarate)-based polymer;composites;characterization;UV-curing;LED encapsulant
研究领域:
材料科学
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高分子化学
·
光电子学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2020
·Vol. 39
·期 4
·493-500
·
IF 3.154
Meng Xiao-Yu,Li Yi,Yao Shu-Fang,Wei Xue-Wei,Ye Hai-Mu
Spherulites are the most common crystalline morphology and thus the visual expression of crystal structures for polymers. The diversified patterns have provided intuitive morphology probes for various crystallization behaviors, while the correlations between them are still needed to be enriched. In this work, the complicated spherulitic morphology of poly(propylene fumarate) (PPF), which is sensitive to crystallization temperature, is investigated. PPF melt, respectively, crystallizes into rough spherulites, regularly banded spherulites, and spherulites containing both two kinds of morphology at low, high, and mediate temperatures. By systematically assaying, it is clear that the growth axis along the radial direction changes from a -axis to b -axis as the crystallization temperature increases, which leads to the formation of unique crystallization-temperature-dependent spherulites. Based on detailed characterization of Fourier transform infrared spectroscopy, the packing state of the specific hydrogen bonds of “C=C-H⋯O=C-C=C” in PPF crystal lattices is determined, and furthermore, the mechanism for temperature-dependent selection of growth axes for PPF spherulites in melt is reasonably speculated.
研究领域:
材料科学
·
高分子化学
✓ 已验证
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2017
·Vol. 40
·期 18
·3710-3717
·
IF 2.557
Xinyu Liang,Juntao Wang,Juanjuan Wu,Qiuhua Wu,Chun Wang,Zhi Wang
A three-dimensional graphene was synthesized through a hydrothermal reaction of graphene oxide with phytic acid. The microstructure and morphology of the phytic acid induced three-dimensional graphene were investigated by nitrogen adsorption–desorption isotherms, scanning electron microscopy, and transmission electron microscopy. With a large surface area and three-dimensional structure, the graphene was used as the solid-phase extraction adsorbent for the extraction of phthalate esters from bottled water and sports beverage samples before high-performance liquid chromatographic analysis. The results indicated that the graphene was efficient for the solid-phase extraction of phthalate esters. The limits of detection (S/N = 3) of the method for the analytes were 0.02–0.03 ng/mL for the water samples and 0.03–0.15 ng/mL for the sports beverage sample. The limits of quantitation (S/N = 9) for the analytes were 0.06–0.09 ng/mL for water samples and 0.09–0.45 ng/mL for sports beverage sample. The calibration curves for the phthalate esters by the method had a good linearity from 0.1 to 80.0 ng/mL with correlation coefficients larger than 0.9997. The recoveries of the analytes for the method fell in the range of 86.7–116.2% with the relative standard deviations between 1.5 and 6.8%.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Zixuan Wang,Wenhao Gao,Zhengchun Cai,Haian Xia
Poly(ethylene 2,5-furandicarboxylate) (PEF) and poly(butylene 2,5-furandicarboxylate) (PBF) are regarded as two of the most promising materials derived from furandicarboxylic acid. The modification of these two polyesters has become one of the hot research topics. It was reported that their mechanical properties had significant shortcomings, particularly for low molecular weight PBF, whose brittleness limited its use. In this work, a novel monomer, itaconic acid, was introduced to modify PBF, and a new furan-based polyester-poly(1,4-butylene furanoate-co-itaconate) (PBFIs) was synthesized. For the first time, itaconic acid up to 47% was incorporated to synthesize the polyester materials. The structural and thermomechanical properties of these polyesters were investigated using Gel Permeation Chromatography (GPC), Proton Nuclear Magnetic Resonance ( 1 H NMR), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), X-ray Diffraction (XRD), and tensile testing. Compared to PBF, the PBFIs exhibited reduced crystallization ability attributed to the formation of crosslinked networks; notably, their glass transition temperature decreased significantly to as low as 7°C, while thermal stability improved. Tensile tests further demonstrated that their elongation at break increased dramatically by up to 675%. In summary, the results suggest that PBFIs possess significant potential in the realm of thermoset elastomers, thereby expanding the application scope of furan-based polyesters.
研究领域:
材料科学
·
聚合物化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Polymer Materials
·
2022
·
IF 4.855
Xin Guan,Ting Wei,Jingting Cai,Jianlin Sun,Sen Yu,Dagang Guo
The design of soft tissue adhesives with excellent adhesive performance has drawn much attention in biomedical applications for the suture-free fixation of soft tissue wounds. Poly(propylene fumarate) (PPF)-based materials exhibit excellent biocompatibility with nontoxic products and high mechanical strength and are widely used as bone repair materials. However, shortcomings, including low adhesive strength, low breathability, and poor hydrophobicity, as well as difficulty in detaching in vitro or degrading in vivo after wound tissue healing, limit the potential application of PPF-based materials in soft tissue adhesives. This study presented a biomimetic nucleobase-tackified strategy for designing PPF-based soft tissue adhesives, where adenine was diffusely distributed as a convex second phase in the PPF matrix and provided multipoint interactions with soft tissues. As a result, adenine increased both the lap shear strength by 200% (1.48 ± 0.10 MPa) and the adhesive strength (1.70 ± 0.08 MPa) by 45% in the early stage, and then with adenine degradation, the multipoint interactions disappeared and simultaneously achieved a removable adhesion function with tissue. Moreover, the formed microscale pores from the adenine degradation site also improved the maximum moisture vapor transmission rate by 238% and the hydrophilicity. This detachable adhesive strategy on PPF-based materials will significantly promote the next generation of soft tissue adhesives for biomedical applications.
研究领域:
生物医学工程
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材料科学
·
组织修复
✓ 已验证
产品关联
DOI
高影响因子
BIOMACROMOLECULES
·
2020
·
IF 6.092
Chao Chen,Ying Tian,Fenglong Li,Han Hu,Kai Wang,Zhengyang Kong,Wu Bin Ying,Ruoyu Zhang,Jin Zhu
Polylactic acid (PLA) is a biodegradable thermoplastic polyester produced from natural resources. Because of its brittleness, many tougheners have been developed. However, traditional toughening methods cause either the loss of modulus and strength or the lack of degradability. In this work, we synthesized a biobased and potentially biodegradable poly(butylene 2,5-furandicarboxylate)-b-poly(ethylene glycol) (PBFEG50) copolymer to toughen PLA, with the purpose of both keeping mechanical strength and enhancing the toughness. The blend containing 5 wt % PBFEG50 exhibited about 28.5 times increase in elongation at break (5.5% vs 156.5%). At the same time, the tensile modulus even strikingly increased by 21.6% while the tensile strength was seldom deteriorated. Such a phenomenon could be explained by the stretch-induced crystallization of the BF segment and the interconnected morphology of PBFEG50 domains in PLA5. The Raman spectrum was used to identify the phase dispersion of PLA and PBFEG50 phases. As the PBFEG50 content increased, the interconnected PBFEG50 domains start to separate, but their size increases. Interestingly, tensile-induced cavitation could be clearly identified in scanning electron microscopy images, which meant that the miscibility between PLA and PBFEG50 was limited. The crystallization of PLA/PBFEG50 blends was examined by differential scanning calorimetry, and the plasticizer effect of the EG segment on the PLA matrix could be confirmed. The rheological experiment revealed decreased viscosity of PLA/PBFEG50 blends, implying the possible greener processing. Finally, potential biodegradability of these blends was proved.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 34
·19712-19719
·
IF 3.049
Jie Zuo,Xingyuan Zhang,Xinyu Li,Zhiwei Li,Zongren Li,Honghong Li,Wencheng Zhang
Molecularly imprinted polymers (MIPs) prepared using conventional functional monomers exhibit poor specific extraction of scopolamine from tropane alkaloids, which hinders their application in separation and purification. In this paper, a novel molecularly imprinted polymer (MIP) was prepared by precipitation polymerization using scopolamine as the template, monoethyl fumarate (MFMA) as a functional monomer, and ethylene dimethacrylate (EGDMA) as a cross-linker. The advantages of the supercritical fluid technology for the removal of the template were verified by comparing the efficiency of the swelling method and the Soxhlet extraction method. The prepared MFMA-based MIPs (MFMA-MIPs) showed a high adsorption capacity (49.75 mg g−1) and high selectivity toward scopolamine with a selectivity coefficient of 3.5. 1H NMR spectroscopy was performed to demonstrate the interactions between the two functional groups of the functional monomer and the template. Lastly, MFMA-MIPs were used as solid phase extraction (SPE) sorbents for scopolamine analysis. It was found that 97.0–107.0% of the template had been extracted using the SPE column from the complex of scopolamine, atropine and anisodamine. The mean recoveries of scopolamine from plant samples were 96.0–106.0% using the established method, which showed a good linearity in the range of 8.0–4.0 × 104 μg L−1. The results showed that MFMA-MIPs could be applied for the separation of scopolamine from tropane alkaloids.
研究领域:
化学
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Additive Manufacturing
·
2021
·
IF 10.998
Wenjie Li,Xiaopeng Cheng,Yuan Wang,Shanfeng Wang
Projection micro-stereolithography (PμSL) is an effective technique to rapidly fabricate porous scaffolds with complex structures of photo-crosslinkable polymer resins, which normally contain a reactive diluent and a photo-initiator. In previous reports on 3D printing of poly(propylene fumarate) (PPF) scaffolds, diethyl fumarate (DEF) was unavoidably used as a reactive diluent in the PPF resin. Here we present a photo-crosslinkable resin composed of PPF and hyperbranched polyester acrylate (HPA), which has multiple carbon-carbon double bonds to participate in photo-crosslinking as a reactive diluent, and PμSL 3D fabrication of tissue-engineering scaffolds using this resin. The structure and viscoelastic behavior of uncrosslinked PPF/HPA, and the gel fraction, thermal and mechanical properties of photo-crosslinked PPF/HPA samples have been investigated, in comparison with those of PPF/DEF. Blending HPA with PPF was found to decrease the viscosity of PPF and to expedite the photo-crosslinking process, both of which are important in formation of PPF networks. In addition, HPA can effectively enhance the stiffness and toughness of the fabricated network simultaneously. In PμSL 3D fabrication, the cure depth (C d ) experiments proved that the PPF/HPA resin had an extremely low critical energy (E c ) of 2.1 mJ/cm 2 , leading to ultra-fast curing when exposed to ultraviolet (UV) light. Our rapid prototyping characteristics are evident under the premise of ensuring high precision. For the PPF/HPA resin, the exposure time per layer was only 0.1–2 s, which at least doubled the printing speed compared with the other 3D fabrication techniques . At high printing resolution of 50 µm, an ultra-fast printing speed of 18 cm/h was achieved by using the PPF/HPA resin, while the value for the PPF/DEF resin was only 3.6 cm/h. Benefited from the better crosslinked networks, the fabricated PPF/HPA scaffolds exhibited a lower shrinkage, higher stiffness and toughness, and better recovery capacity than their PPF/DEF counterparts, indicating their 4D printing characteristics.
研究领域:
生物医学工程
·
组织工程
✓ 已验证
DOI
高影响因子
Materials Today Communications
·
2021
·
IF 3.383
Bushra Naureen,A.S.M.A. Haseeb,W.J. Basirun,Farina Muhamad
Tissue degeneration due to diseases, accidents, and wars is a worldwide issue. One of the methods used by regenerative medicine (RM) to aid tissue repair is by using a biodegradable tissue engineering scaffold (TES). Different body tissues have variable regeneration abilities, and hence, they require TES with variable degradation rates. This paper focuses on synthesising four polyurethane foam scaffolds (PUFS) with variable degradation rates based on the concentration of incorporated chain extender (CE) poly[(R)-3-hydroxybutyrate] (P3HB). The polyol employed is poly (propylene fumarate) (PPF) along with aliphatic 1,6-hexamethylene diisocyanate (HDI). GPC provided the molecular weight (M n = 455.67 g mol −1 , M w = 587.15 g mol −1 ) and PDI (1.29) of the PPF. FTIR and 1 H and 13 C NMR confirmed the proposed structures (C C, COOR, and NHCOO) of the PUFS. The FESEM images revealed a bimodal pore structure , with random, irregular, interconnected pores (242–340 µm) and discrete void spaces (735–860 µm). The size of PUFS pores and void spaces (PU4 > PU3 > PU2 > PU1) is directly proportional to their respective degradation rates. The TGA/DTA curves show a decrease of an onset thermal decomposition temperature from PU1 to PU4 (267.17 ºC PU1, 267.28 ºC PU2, 256.01 ºC PU3 and 240.72 ºC PU4) due to the respective increase in CE concentration. The results of in-vitro degradation analysis at day 70, revealed significant difference between the weight loss (%) of each group (PU1 = 4.09 ± 0.18%, PU2 = 8.03 ± 0.17%, PU3 = 13.14 ± 0.12% and PU4 = 20.21 ± 0.19%). Thus, PUFS with a higher concentration of P3HB have a faster degradation rate due to the associated P3HB hydrolysable ester/-COOR functional group within the PUFS backbone. The chemical structure , bimodal morphology, and variable degradation rate of these PUFS could be employed for various RM applications.
研究领域:
生物材料学
·
再生医学
·
高分子化学
✓ 已验证
DOI
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2022
·Vol. 40
·期 6
·602-610
·
IF 3.815
Wei Xue-Wei,Zhao Xin-Xin,Li Yi,Meng Xiao-Yu,Zhou Qiong,Ye Hai-Mu
Co-crystallization of different monomeric units fundamentally contributes to the versatile and tunable performance of random copolymers. At present, the crystallization manners of random binary copolymers have been divided into three categories: isomorphism, isodimorphism and comonomer exclusion. Each category, however, has its own advantages and disadvantages. Therefore, it is challenging to design and prepare random copolymer sharing the advantages of isomorphism and isodimorphism through a new co-crystallization manner beyond the ones already exist. On the basis of previous study on poly(alkylene succinate- ran -alkylene fumarate) whose co-crystallization can be extensively and finely regulated by simply varying the chemical structure of alkylene, random copolymers of poly(propylene succinate- ran -propylene fumarate) (PPSF) are synthesized using 1,3-propanediol as the diol source. The thermal properties and crystal structure of PPSF are investigated, and, intriguingly, it is proved that PPSF is an isodimorphism system while displays similar composition-dependent thermal properties and crystallinity as isomorphism. That is, PPSF exhibits a novel co-crystallization behavior that has rarely been discovered, which would combine the advantages of both isomorphism and isodimorphism. Consequently, PPSF could be termed as a new-type, special composition-dependent polymorphism. Besides, the altering of PPS-like to PPF-like crystal structure of PPSF when changing chain composition has been proved to originate from the shift of dominant inter-segment interaction from van der Waals forces to strong hydrogen-bonding interaction. This work enriches the co-crystallization manner of random copolymers, leading to more diverse performance design of polymer materials.
研究领域:
高分子化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Rui Du,Bin Zhao,Kun Luo,Man-Xi Wang,Quan Yuan,Lei-Xiao Yu,Ke-Ke Yang,Yu-Zhong Wang
Bone tissue engineering involving scaffolds is recognized as the ideal approach for bone defect repair. However, scaffold materials exhibit several limitations, such as low bioactivity, less osseointegration, and poor processability, for developing bone tissue engineering. Herein, a bioactive and shape memory bone scaffold was fabricated using the biodegradable polyester copolymer’s four-dimensional fused deposition modeling. The poly(ε-caprolactone) segment with a transition temperature near body temperature was selected as the molecular switch to realize the shape memory effect. Another copolymer segment, i.e., poly(propylene fumarate), was introduced for post-cross-linking and improving the regulation effect of the resulting bioadaptable scaffold on osteogenesis. To mimic the porous structures and mechanical properties of the native spongy bone, the pore size of the printed scaffold was set as ∼300 μm, and a comparable compression modulus was achieved after photo-cross-linking. Compared with the pristine poly(ε-caprolactone), the scaffold made from fumarate-functionalized copolymer considerably enhanced the adhesion and osteogenic differentiation of MC3T3-E1 cells in vitro. In vivo experiments indicated that the bioactive shape memory scaffold could quickly adapt to the defect geometry during implantation via shape change, and bone regeneration at the defect site was remarkably promoted, providing a promising strategy to treat bone defects in the clinic, substantial bone defects with irregular geometry.
研究领域:
组织工程
·
生物材料
·
骨科研究
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2024
·
IF 5.5
Wali Muhammad,Min Liang,Beiduo Wang,Jieqi Xie,Wajiha Ahmed,Changyou Gao
N-Acetyl cysteine (NAC) is an essential molecule that boosts acute lung injury (ALI) defense via its direct antioxidant capability. Nevertheless, the therapeutic use of NAC is limited due to its poor bioavailability and short half-life. In this study, NAC was grafted to the polyurethane consisting of poly(propylene fumarate), poly(thioketal), and 1,6-hexamethylene diisocyanate (PFTU) to reduce excessive oxidative stress and inflammatory factors in ALI. The NAC-grafted polymer nanoparticles (NPT@NPs) were prepared as a drug delivery system, which could effectively scavenge free radicals and reduce inflammation in vitro. The administration of NPT@NPs exhibited notable efficacy in ameliorating pulmonary edema, attenuating the presence of inflammatory cells, suppressing myeloperoxidase expression, diminishing the levels of pro-inflammatory cytokines, and reversing cell apoptosis in an ALI model induced by lipopolysaccharide (LPS). The NPT@NPs demonstrated significantly better efficacy compared to the free NAC in mitigating the deleterious effects of LPS on pulmonary tissue, thereby providing more effective protection against pulmonary inflammation.
研究领域:
药理学
·
纳米技术
·
肺科学
·
炎症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）