JOURNAL OF HAZARDOUS MATERIALS
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2019
·
IF 7.65
Wei Jiang,Qiang Xu,Xionghui Wei
It is first reported herein that cobalt(II) complexes solution of monothiol-containing multidentate ligands are used to remove low concentration of nitric oxide (NO). These chelating ligands are water-soluble amines, alcohols or acids which containing at least one -SH group, include those of cysteine, mercaptosuccinic acid, mercaptoethanesulfonate, mercaptopropionic acid and the like. These -SH compounds when coordinated with cobalt ions, forming complexes are very effective for NO removal. The results indicate that the side group (methyl, carboxyl, carboxymethyl) on α-carbon atom of ligands contribute to the denitration of the chelate solution, whereas the substituents on sulfur atom of ligands deactivate the complexation system. In addition, we have found that several monothiol compounds with simple molecule structure and low cost exhibit good performance in denitration, and some of cobalt thiol complexes are more valuable in removing NO than ferrous thiol complexes.
研究领域:
化学
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环境科学
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材料科学
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PubMed
高影响因子
Natural Product Communications
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2020
·
IF 0.468
Bo Tao,Zong-ning Yin
Thiolated hyaluronic acid was synthesized, and a quantification method was established to determine the content of the thiol group. Three thiol compounds, 2-nitro-5-mercapto-benzoic acid (TNB), 2- mercaptonicotinic acid (2-MNA), and mercaptopyridine (MPD), were tested for their efficiency in forming adducts with hyaluronic acid (HA) through disulfide bonds. Our results showed that MPD exhibited the highest disulfide exchange efficiency when the reaction was conducted at the optimal pH value. The synthesized hyaluronic acid-SS-mercaptopurine (HA-SS-MP) was characterized by 1H-nuclear magnetic resonance spectroscopy. The HA-SS-MP micelle showed a particle size of 264.4 nm in aqueous solution. An in vitro release experiment demonstrated that the releasing rate of 6-MP from HA-SS-MP in the release medium containing glutathione (GSH) was much higher than that in the release medium without GSH. Cell uptake experiments demonstrated the CD44 targeting of hyaluronic acid. Cytotoxicity tests in mouse melanoma cells (B16F10) showed that HA-SS-MP can kill melanoma cells effectively and with lower cytotoxicity, compared with the active ingredient, 6-MP.
研究领域:
药学
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肿瘤学
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生物化学
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高影响因子
Polymer Chemistry
·
2011
·Vol. 3
·期 7
·1918-1925
·
IF 0
Jin Han,Bo Zhao,Aijin Tang,Yanqin Gao,Chao Gao
Fast and scalable production of hyperbranched polythioether-ynes was achieved by applying sequential click chemistry (SCC) via couple-monomer methodology (CMM). As a typical example, thiol-halogen click-like reaction employing strong base, KOH and thiol-yne click reaction via UV irradiation were used for precursor preparation and polymerization, respectively. Two series of hyperbranched polythioether-ynes employing two kinds of di-thiols with different reactivity have been prepared within 10 h and characterized with 1H NMR spectroscopy and gel permeation chromatography. The hyperbranched polymers (HPs) derived from 1,6-hexanedithiol reached high weight-average molecular weight (Mw) of 230500, high weight-average degree of polymerization (DPw) of 1224 and high degree of branching (DB) of 0.82–0.68. Postmodification of abundant alkyne terminal groups afford HPs with a greatly enhanced DB of 0.96. Heat-initiated polymerization was also attempted. The present study clearly demonstrates the robustness of application of SCC technique in the CMM strategy for fast, scalable preparation of multifunctional HPs.
研究领域:
材料科学
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化学工程
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DOI
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Qianqian Zhang,Qi Guan,Shengping Han,Xianzai Yan,Jiaxin Hong,Luying Duan,Guoqiang Wu,Yanping Hong,Lili Yu,Chunrong Wang
In this study, a simple, rapid and sensitive tryptophan (Trp) detection method was proposed, which combined surface enhanced Raman spectroscopy (SERS) with diazo coupling reaction and silver dendritic substrate. Two derivatization reagents, 4-mercaptoaniline (PATP) and 2-fluoro-4-mercaptoaniline (2-F-PATP) were used for derivatization reaction with Trp, which can be controlled by experimental parameters such as derivatization reagent concentration and sodium nitrite concentration. The partial least squares quantitative (PLS) detection model is applied in determining the concentration of Trp. The determination coefficient (R 2 ) of PLS model was 0.9617 based on PATP and 0.9950 on 2-F-PATP. The LOD of the two derivatization methods were as low as 10 −11 mol/L. This combined technique has the characteristics of simple operation, high sensitivity and good selectivity, and shows great potential in the detection of Trp in biological media.
研究领域:
分析化学
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生物化学
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高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 6
·771-777
·
IF 3.1
Ying-Hua Zhou,Chen-Chen Jiang,Zhou Yu,Ya-Hao Wang,Ju-Fang Zheng,Xiao-Shun Zhou
Electroreductive dehalogenation as an efficient and green approach has attracted much attention in pollution remediation. Herein, we have employed a shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) technique to in situ probe the electroreductive dehalogenation process of aryl halides with thiol groups at Ag/aqueous solution interfaces. It is found that 4-bromothiophenol (BTP) and 4-chlorothiophenol (CTP) can turn into mixed products of 4,4′-biphenyldithiol (BPDT) and thiophenol (TP) as the electrode potential decreases. The conversion ratios estimated from the Raman intensity variations of C–Cl and C–Br vibrations are 44% and 58% for CTP and BTP in neutral solution, respectively. Furthermore, the quantitative analysis of benzene ring vibrations reveals a C–C cross coupling between the benzene free radical intermediate and adjacent TP product, which results in increased selectivity for biphenyl products at negative potentials.
研究领域:
环境科学
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电化学
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光谱学
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PubMed
高影响因子
FOOD CHEMISTRY
·
2020
·
IF 6.306
Yue Hu,Yingping Li,Yunwen Liao,Xiaohui Jiang,Zhengjun Cheng
A water-soluble, long-term stable, poly(sodium-p-styrenesulfonate)-enhanced and d -penicillamine stabilized argentum nanoclusters (PSS-DPA-AgNCs) was synthesized by a one-step ultraviolet radiation combined with microwave heating method. The effects of different types of polyelectrolytes and energy suppliers on the AgNCs photo-luminescence performance were investigated in detail. The prepared AgNCs are exhibited to be viable fluorescent method for 2-Mercapto-3-butanol (2-M-3-B), 3-Mercapto-2-butanone (3-M-2-B) and silicate (SiO 3 2− ) determinations. The fluorescence (FL) of PSS-DPA-AgNCs is quenched with the addition of 2-M-3-B/3-M-2-B/SiO 3 2− mainly originating from a static quenching process. The method can monitor 2-M-3-B/3-M-2-B by fluorometry with a linear response in the range of 0.33–90.0/0.33–80.0 μM and a 74/250 nM detection limit (at 3σ/slope). For the SiO 3 2− assay, corresponding data are 3.33–100.0 μM and 278 nM. Moreover, the proposed method was successfully used for the assays of two food flavors in the steamed bread and soda drinks, and silicate in the mineral water samples respectively.
研究领域:
分析化学
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食品科学
·
纳米技术
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PubMed
高影响因子
CARBOHYDRATE POLYMERS
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2018
·
IF 5.158
Pan Zhang,Nan Zhang,Qiang Wang,Ping Wang,Jiugang Yuan,Jinsong Shen,Xuerong Fan
Chitosan, a natural biopolymer, is used as a multifunctional agent for modification of wool either through chemical crosslinking or physical coating. For the first time, wool fabric has been modified with chitosan through disulfide bond breaking and reforming reactions. The chitosan was thiolated and then grafted onto the reduced wool fibers through disulfide bonds. In order to understand the mechanism of the grafting of thiolated chitosan onto wool, glutathione was used as a model compound for wool in the research. The structures of thiolated chitosan reacted with glutathione and wool fabrics grafted with thiolated chitosan were investigated by FTIR, 13 CNMR, XPS, XRD, SEM. The dyeability, shrink-resistance and biocompatibility were also tested. The results suggested that glutathione reacted with thiolated chitosan and formed disulfide bond. The thiolated chitosan-grafted wool fabric had good shrink-resistance and dyeability. Hydrophilicity and antibacterial properties were also improved compared with untreated wool fabric. The results provide a novel approach for modification of wool through fiber-intrinsic groups like disulfide bonds.
研究领域:
材料科学
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纺织工程
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生物化学
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PubMed
高影响因子
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN
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2015
·Vol. 123
·期 1441
·719-724
·
IF 0.698
Liguo LI,Shengyu FENG,Hongzhi LIU
Multicarboxy (8, 16) functionalized cage silsesquioxanes were synthesized through the photochemical thiol-ene reaction of octavinylsilsesquioxane with 3-mercaptopropionic acid and mercaptosuccinic acid, respectively. These two cage precursors acted as ligands to coordinate with terbium ion (Tb3+) to obtain two novel hybrid luminescent materials, which exhibited fine luminescent properties and good thermal stabilities. Their morphologies were investigated by XRD, SAXS, SEM, TEM and DLS. And the results showed that self-assembly particle size of the hybrid complex with octacarboxyl cage was larger size than that of cage with 16 carboxyl groups.
研究领域:
材料科学
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化学
·
纳米技术
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Yu-Fei Li,Can-Jun Zou,Xing-Biao Liu,Feng Gan,Ping-Ping Fang
The detection of pharmaceuticals has been a matter of concern among scientists and health researchers in the past few decades. However, it is still difficult to realize the sensitivity and selectivity detection of pharmaceuticals with similar structures. Herein, the pharmaceutical molecules of 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT) with so similar structures can be selectively detected by surface-enhanced Raman spectroscopy (SERS) taking advantage of the fingerprint identification on Au/MIL-101(Cr), with sensitive detection limits of 0.5 ng·mL–1 for MBI and 1 ng·mL–1 for MBT. MBI is selectively enriched by Au/MIL-101(Cr) from the mixture solution and detected by SERS below 30 ng·mL–1. MBI can also be selectively detected in the serum samples with a detection limit of 10 ng·mL–1. Density functional theory calculations combined with the SERS experiments explained that the high sensitivity and selectivity are caused by the intrinsic differences in Raman intensity and different adsorption energies from the pharmaceutical molecules adsorbed on Au/MIL-101(Cr), respectively. This study provides an effective way to enrich and detect pharmaceutical molecules with similar structures.
研究领域:
分析化学
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药学
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材料科学
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PubMed
高影响因子
CHEMOSPHERE
·
2020
·
IF 5.778
Yunfeng Xu,Kaili Wang,Qinghao Zhou,Liting Zhang,Guangren Qian
The ability of thiol-modified humic acids (HAs) to release arsenic in tailings soil after being modified with different sulfur-containing reagents were significantly improved. The structure and physicochemical properties of humic acid (HA) before and after thiol-modification were characterized. The 3-MPTS-HA treated with 3-mercaptopropyltrimethoxysilane (3-MPTS) effectively improved the mobility of arsenic, and its reducing ability was increased from 2 mmol g −1 to 3.54 mmol g −1 . The S content of humic acids were also significantly increased after treatment with sulfur-containing reagents, in which the oxygen-containing functional group (e.g., C = O, C–O) on the surface of HA may be the active sites for binding with sulfur-containing reagents. It was found in the XPS spectrum that because the thiol group is easily oxidized, there are many S forms in thiol-modified HA. The –SH content in Na 2 S·9H 2 O-HA, l (+)-Cysteine-HA (Cys-HA), thioglycolic acid (TGA-HA) and 3-MPTS-HA was determined by fluorescence method to be 13.9, 78.45, 90.34, and 192.29 μmol g −1 , respectively. The study demonstrated that surface thiol modification can increase the abundance of thiol in HA and enhance reactivity, which will further promote the application of HA in the treatment of heavy metal contaminated tailing soil.
研究领域:
环境科学
·
土壤学
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PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Kang Shen,Caili Bi,Haifan Yang,Miaowen Xu,Lili Huang,Youwei Wang
Based on the coordination principle of Lewis acid, the 4-mercaptophenylboronic acid (4-MPBA)-modified novel dumbbell-shaped Au-Ag nanorods (4-MPBA@DS Au-AgNRs) substrate has been developed, which could be combined with the surface-enhanced Raman scattering (SERS) technique to detect SO42- with high sensitivity and specificity. DS Au-AgNRs synthesized in this paper with dumbbell particular structure have been verified by finite-difference time domain (FDTD) simulation to be capable of stimulating strong localized electromagnetic enhancement (EM) at nano-edge, gap, generating a large number of “hot spots” exhibiting excellent SERS performance. The 4-MPBA modified on its surface could specifically recognize SO42-, producing a change in the spectral peak at 1382 cm-1, thus realizing highly sensitive and specific sensing of SO42-. Under optimized conditions, this SERS sensor responded rapidly to SO42- within 2 minutes and demonstrated uncommon immunity. Ratio calculation by the ratio of the characteristic peaks at 1382 and 1070 cm-1 (I1382/I1070) enabled quantitative detection of SO42- in the range of 1 × 10-8-1 × 10-3 M, and the detection threshold was as low as 1 nM, which was superior to that of similar detection methods. Importantly, the utility and reliability of this SERS substrate for the determination of SO42- in actual samples were evaluated using ion chromatography as the gold standard, and there was no significant difference between the two protocols (P > 0.05), and the RSD was less than 6% with a satisfactory recovery rate (97.6-102.3%). Therefore, the present protocol has the advantages of simplicity and rapidity, high sensitivity, specificity, stability, and practicability in the determination of SO42- in aqueous solution, providing a reliable solution for tracing SO42- in the field of food safety and environmental testing.
研究领域:
分析化学
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环境科学
·
食品安全
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 42
·19957-19962
·
IF 3.591
Yan Xu,Xiao-Sheng Yan,Si-Bo Zhang,Shao-Wei Li,Ning-Shao Xia,Tao Jiang,Zhao Li,Yun-Bao Jiang
We report a supramolecular nanosphere with a diameter of 8.65 nm built in an aqueous solution via dynamic binding of glucose to a thiol ligand bearing a phenylboronic acid group, 4-mercaptophenylboronic acid (4-MPBA), as a hydrophilic component in combination with a hydrophobic thiol ligand, 1-octanethiol (n-C8H17SH), in the presence of Ag+. Highly hydrophilic glucose binding to two neighboring boronic acid groups from 4-MPBA ligands on their Ag+ coordination polymeric backbone, on which the hydrophobic n-C8H17SH ligands locate inwards, drives the coordination polymers into nanospheres. The supramolecular nanospheres are of small diameters with narrow size distribution characteristic of glucose among the tested monosaccharides including fructose and xylose.
研究领域:
材料科学
·
化学
·
纳米技术
·
超分子化学
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高影响因子
危险品化学品经营许可证（带存储）