ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Wenfu Lin,Yan Huang,Zhenru Li,Jiongshen Pan,Tiansheng Huang,Lili Liang,Yanzhen Tan,Jie Li,Li-Peng Sun,Bai-Ou Guan
Humidity plays an important role in many fields, and the realization of high sensitivity and fast response simultaneously for humidity detection is a great challenge in practical application. In this work, we demonstrated a high-performance relative humidity (RH) sensor made by supporting zeolitic imidazolate framework-90 (ZIF-90)-derived porous zinc oxide (ZnO) onto an optical microfiber Sagnac interferometer (OMSI). The ZIF-90-modified OMSI (ZIF-90-OMSI) sensor was in situ heated at different temperatures to obtain porous ZnO, and their humidity-sensing properties were investigated ranging from 25 to 80% RH. The experimental results showed that the porous ZnO fiber sensor prepared at 500 °C (Z500-OMSI) exhibited best humidity-sensing performance with a high sensitivity of 96.2 pm/% RH (25–45% RH) and 521 pm/% RH (50–80% RH) and ultrafast response/recovery time (62.37/206.67 ms) at 22.3% RH. These performances were attributed to the complete transformation of ZIF-90 to ZnO at 500 °C. The obtained Z500 not only retained the high porosity and specific surface area of ZIF-90 but also exhibited the exceptional hydrophilicity of ZnO. In addition, the signals of the proposed Z500-OMSI sensor changed with different breathing patterns, indicating the possibility for human respiration monitoring. This work provided a reliable candidate for an effective RH monitoring system with potential application in medical diagnoses, industrial production, environmental detection, and human health monitoring.
研究领域:
光学传感
·
材料科学
·
生物医学工程
·
环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2024
·
IF 4.1
Wang Ya-Jie,Zhang Ping,Serpe Michael J.,Chen Hong,Hu Liang
Photonic materials, which react to light, have garnered interest due to their capability to exhibit adjustable structural colors. Typically, light targets the UV, visible, or near-IR spectrums. In this study, microgel-based photonic materials that are capable of reversibly responding to X-rays have been engineered. To accomplish this, azobenzene (Azo)-containing poly( N -isopropylacrylamide) (pNIPAm)-based microgels are synthesized. Subsequently, ZnS scintillator and Cr/Au are applied on each side of the poly(methyl methacrylate (PMMA) substrate. Subsequently, the Azo MG monolayer is deposited onto the Au surface, followed by the deposition of an additional layer of Cr/Au. This process generates ZnS/PMMA/Cr/Au/Azo MG/Cr/Au or ZnS/Au-Azo MG-Au structure. Functioning as a typical interferometer, ZnS/Au-Azo MG-Au demonstrates tunable colors based on the separation distance between the two Au layers. The ZnS scintillator can absorb and convert X-rays into UV light, initiating the transition of the Azo groups from a trans to a cis state. Consequently, this transition causes the Azo MG to swell. As Azo MG swells, the distance between the two Au layers increases, resulting in a red-shift of approximately 350 nm in the optical signal of the ZnS/Au-Azo MG-Au interferometer. Remarkably, this X-ray responsivity of the interferometer is reversible, as it returns to its initial state after being stored in the dark for 24 h. To demonstrate its capabilities, the ZnS/Au-Azo MG-Au interferometer successfully releases a drug when triggered by X-ray stimulation, thus validating its potential. The microgel-based interferometers hold significant promise for applications in chemoradiotherapy, radiobiology, and actuators in space.
研究领域:
生物医学工程
·
材料科学
·
放射生物学
✓ 已验证
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Xiaoliang Zhang,Xiaohong Chen,Xiaofang Shi,Xiaochun Li,Hua-Zhong Yu
A microanalytical technique based on the photothermal effect in conjunction with back-scattering interferometry (BSI) using a single laser beam was developed for quantitative detection of heavy metals. After the chromogenic reaction of an analyte in a capillary tube, the photothermal effect induced by irradiation with the same laser beam leads to a change of the refractive index of the solution, which can be “quantified” using the BSI technique. For prove-of-concept, Cu(II) was chosen as the trial analyte, for which the solution changes to purplish through reacting with the chromogenic reagent; a single laser beam of 532 nm was adapted for both inducing the photothermal effect and realizing BSI detection. With as little as 1.0 μL solution, a limit of detection (LOD) of 0.10 mg/L for Cu(II) was achieved. In addition, the versatility of the technique was demonstrated by detecting other two heavy metal ions, Fe(II) and Cr(VI), with limits of detection of 0.06 mg/L and 0.04 mg/L, respectively. The demonstrated detection sensitivity, application versatility, and instrumentation simplicity of this new technique promises it as a practical tool for environmental monitoring and beyond.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Wei Li,Xuerui Zhu,Xin Wang,Jie Liu,Baowen Liang,Tiesong Zheng,Jianlin Li
A new real-time monitoring method for alcohol content in spirit samples has been established on base of stable TiO 2 -coated porous silicon (PSi) interferometer. There is a linear relationship between the different alcohol contents in range of 10%–70% (v/v) and efficient optical thickness (EOT) or the reflection peak positions of the sensing film. The alcohol content of sample can be measured by the EOT or the reflection peak positions with the TiO 2 coated PSi interferometer. Both the straight TiO 2 -PSi and rugate TiO 2 -PSi can detect the alcohol contents, but the former displays a sensitivity of 2.911 nm ± 0.145/alcohol content unit (ACU) which is fifty times more sensitive than that of the latter. The developed method is a rapid, sensitive, on-line, and cost-efficient detection technique without sample pretreatment for alcohol content in spirit samples. The results detected by the developed method for alcohol content in nine spirit samples are agreement with that of traditional alcoholmeter method. The novel established method has a great potential in food industry, environment and health fields for monitoring alcohol content.
研究领域:
食品科学
·
光学传感
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
iScience
·
2022
·
IF 6.107
Yueying Liu,Zhenguo Jing,Qiang Liu,Ang Li,Wenwen Li,Sen Zhang,Ang Lee,Fu Tian,Rui Li,Wei Peng
An integrated aerodynamic three-hole pressure probe (THP) based on a fiber-optic tip sensor array for high-velocity flow field vector measurement is developed and demonstrated in wind tunnel testing. The sensor array consisting of three miniature pressure fiber-tip sensors is integrated into three pressure conduits inside top area of the THP, which serves to mitigate pneumatic pressure loss and is expected for a more reliable analysis of flow characteristics. Fast real-time data acquisition is implemented by a compact self-developed multichannel white light interferometry (WLI) interrogator. Well-calibrated maps of the fiber-optic THP are developed in a subsonic free-jet wind tunnel to derive the velocity vectors in a yaw angular range of ±15° at Mach numbers of 0.2 Ma (∼70 m/s), 0.5 Ma (∼170 m/s), and 0.8 Ma (∼300 m/s) while related flow characteristics are analyzed. This work is desired to provide a potential candidate for turbomachinery experimental investigation in fluid mechanics community.
研究领域:
流体力学
·
航空航天工程
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Po Jin,Ya-nan Zhang,Zhong Li,Wanlu Zheng,Liangliang Cheng,Like Li,Xuegang Li,Yong Zhao
Background The concentration of cytochrome C is demonstrated to be an effective indicator of the microbial corrosion strength of metals. Traditional cytochrome C sensor can detect cytochrome C with a low detection limit, but their use is limited by their high cost, cumbersome operation, and susceptibility to malignant environments. In addition, studies on the monitoring of cytochrome C in the field of microbial corrosion has still not been carried out. Therefore, there is a need for a highly sensitive, selective, low-cost, anti-interference, and stable cytochrome C sensor with online monitoring and remote sensing capabilities for in-situ measurement of microbial corrosion strength. Results This paper proposed a highly sensitive label-free fiber-optic sensor based on Mach-Zehnder interferometer (MZI) for in-situ measurement of the microbial corrosion marker cytochrome C. Two-dimensional Ti 2 C-MXene material is uniformly immobilized onto the surface of the sensing area to improve the sensitivity, hydrophilicity , and specific surface area of the sensing area, as well as to facilitate the immobilization of specific sensitive materials. The cytochrome C antibody is modified on the surface of Ti 2 C-MXene to specifically recognize cytochrome C, whose concentration variation can be measured by monitoring the spectral shift of MZI sensor. Results demonstrate a measurement sensitivity of 1.428 nm/μM for cytochrome C concentrations ranging from 0 to 7.04 μM. The detection limit of the sensor is calculated to be 0.392 μM with remarkable performance, including selectivity , stability, and reliability. Besides, the measurement result of the proposed sensor in real microbial corrosive environment is consistent with that of the ideal environment. Significance and novelty This is the first instance of achieving in-situ and label-free measurement of cytochrome C by using a fiber-optic MZI sensor, which undoubtedly provides a feasible solution for the effective monitoring of microbial metal corrosion in the environment.
研究领域:
生物化学
·
材料科学
·
传感技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LIGHTWAVE TECHNOLOGY
·
2024
·
IF 4.1
Yuhan Sun,Zhigang Cao,Guosheng Zhang,Siyang Zhao,Jun Liu,Xingyun Wang,Rui Cheng,Zihan Lin,Zhijia Hu,Siqi Li,Benli Yu
Lead pollution, especially in water, threatens human health. Therefore, it is crucial to quickly and accurately determine the content of lead ions (Pb2+) in drinking water. In this paper, a highly sensitive Pb2+ optical fiber sensor based on a hydrogel-coated Mach-Zehnder interferometer (MZI) is presented. The hydrogel, crosslinked by hydroxyethyl methacrylate (HEMA), acrylic acid, and acrylamide, exhibits excellent specificity, and its porous structure enhances adsorption, ensuring high detection sensitivity and accuracy. Additionally, the MZI with a refractive index sensitivity of -11235.4 nm/RIU is fabricated by fusing three sections of NCF with a lateral offset structure. Then, the hydrogel is coated onto the misalignment area to complete the sensor. The chemical reaction between HEMA and Pb2+ alters the refractive index of the hydrogel, allowing the MZI to detect Pb2+. The sensor has a compact structure with a sensing length of only 0.6 mm. Experimental results show that the proposed Pb2+ sensor has a high detection sensitivity of 4.933×107 nm/(mol/L) and a limit of detection (LOD) of 2.007×10-9 mol/L (0.4199 ppb). Through comparison, the response of Pb2+ is 3.3 times higher than that of other heavy metal ions, indicating that the sensor has good selectivity. In addition, the sensor has excellent repeatability and can be used as a disposable detection product, ensuring the accuracy of the detection results. The sensor demonstrates significant potential applications for Pb2+ detection.
研究领域:
环境科学
·
生物医学工程
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Feng Wu,Yaoyang Li,Linlin Zhang,Yuchen Zhou,Yili Xu,Youpeng Cai,Lingling Ding,Leilei Zhang,Yanfeng Wang,Hui Qian
Extracellular vesicles (EVs) are progressively becoming novel instruments for clinical therapeutics and liquid biopsies. Due to the complexity of biofluids and the physicochemical properties of EVs, the biological activity, velocity, and efficiency of EV isolation are always unsatisfying. Here, we present a real-time isolation approach of EVs derived from cells and urine using ordered porous layer interferometry with a silica colloidal crystal film as the sensing substrate, achieving efficiency greater than 90%. The online concentration detection function is performed during the isolation process on the basis of its real-time monitoring characteristic. Using membrane protein markers of urine EVs as targets, this technique has a high diagnostic value for liquid biopsy of prostate cancer. Furthermore, we compared multiple EV membrane protein expression and binding dissociation kinetic data from cells and urine. In summary, this multifunctional approach provides a novel strategy for the rapid EVs isolation, concentration detection, drug target screening, and liquid biopsy of various body fluids.
研究领域:
生物医学工程
·
临床医学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS
·
2025
·Vol. 25
·期 3
·920
·
IF 3.5
Ning Wang,Shiqi Liu,Liang Xu,Longjiao Wang,Ming He,Chuanjie Lei,Linyufan Xiao
This work proposes an optical fiber copper ion sensor, which is fabricated by an ion-imprinted sodium alginate/graphene oxide (SA/GO) hydrogel and single-mode fiber (SMF). This sensing Fabry–Perot Interferometer (FPI) achieves −1.98 nm/(mg/L) sensitivity with 0.998 linearity. To achieve higher sensitivity, we add a reference FPI to create a Vernier effect. We achieve 19.58 nm/mg/L sensitivity and 0.989 linearity at a concentration range of 0 mg/L–1.4 mg/L. It was 9.9 times higher than that of a single-sensing FPI. The experimental results also demonstrate that when the FSR values of two FPIs are closer, the higher response sensitivity is achieved. The sensor also has good measurement repeatability and dynamic response. In addition, the experimental results of response selectivity show that its response sensitivity to copper ions is significantly higher than other six types of ions, including iron ions, lead ions, magnesium ions, manganese ion, zinc ions, chromium ions. The copper ion is also mixed with six types of ions to deeply investigate the response selectivity. Good response selectivity and cross-responding are demonstrated by experimental results.
研究领域:
材料科学
·
光学传感
·
环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS
·
2018
·Vol. 18
·期 11
·3757
·
IF 2.475
Cuixia Guo,Xiaojie Yang,Zhiyuan Shen,Jian-Ping Wu,Suyi Zhong,Yonghong He,Tian Guan,Fangyi Chen
A phase-sensitive fluidic biosensor based on a spectral-domain low-coherence interferometer is presented in this paper. With a fiber optic probe employing the common-path interferometric configuration, subnanometric changes in thickness of the molecular layers can be detected through phase analysis of the acquired interference signal from the sensor surface. Advantages of this biosensor include its picometer-scale thickness sensitivity, 13.9-ms time response, and tolerance to the fluctuation in concentration of the target solution. The capabilities of this biosensor in monitoring specific molecular binding and recognizing specific molecular was successfully demonstrated by using the reactions between the molecules of protein A and IgG. The calculated minimum detectable concentration of IgG is 0.11 µg/mL.Keywords:phase-sensitive;low-coherence spectral-domain interferometer;fluidic;immunoassays
研究领域:
生物传感器
·
光学干涉测量
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
2D Materials
·
2019
·Vol. 6
·期 4
·045007
·
IF 7.343
Yunyun Huang,Aoxiang Xiao,Guanhua Hou,Hongtao Li,Pengwei Chen,Chaoyan Chen,Bai-Ou Guan
Exploring the photothermal-induced deformation dynamic and mechanism of nanohybrids is of fundamental importance for smart material design and processing at the nanoscale. Here, an optical microfiber interferometer is employed to explore the impact of MoS2 supporting interface on the photothermal-induced deformation of gold nanoshells. Upon analyzing the optical spectra recorded by the microfiber and transmission electron microscopy images, it appears that the MoS2 supporting interface enhances the photothermal effect of the gold nanostructures and confines the electric field oscillation to the nanoshells. Thus, the shape and size evolution of the gold nanoshells are greatly affected by the presence of MoS2 supporting interface. The facile photothermal-induced transformation of the gold nanoshell-MoS2 nanohybrids indicates their technological applications, including catalysis and electronic/optical devices. Furthermore, this transformation process was monitored by an optical microfiber through its evanescent field. This demonstrates the feasibility of using optical fibers to study the inner mechanisms of material transitions in situ, providing a fundamental basis for smart material development at the nanoscale.
研究领域:
纳米材料
·
光学
·
材料科学
✓ 已验证
DOI
高影响因子
OPTICS AND LASER TECHNOLOGY
·
2024
·
IF 4.6
Like Li,Ya-nan Zhang,Mingyue Wang,Hongrui Zhang,Yong Zhao
Real-time and in-situ monitoring the gelation temperature information of the polyacrylamide hydrogel is of great significance for revealing its reaction kinetics information and regulating the performance and quality. In this paper, based on PDMS sensitized in-fiber Mach-Zehnder interferometer (MZI), a sensitive temperature sensor with a temperature sensitivity of 10.22 nm/℃ is proposed, which is used for in-situ thermal monitoring of the gelation process of polyacrylamide hydrogel. By establishing the gelation thermal curve, it is demonstrated that the gelation process mainly includes four stages: initial lag, rapid gelation, cooling stage and stabilization stage. Among them, the rapid gelation stage is the most critical, which shows the heat released in the gelation process and the gelation time. In addition, experimental results confirmed that with the increase of monomer and crosslinker concentration, the heat released during the gelation process gradually increases, but the gelation time is almost unaffected. Since the proposed PDMS sensitized MZI sensor has the advantages of miniaturization, high sensitivity, intrinsically safe, etc., it can be further extended to other dynamic reaction processes for real-time monitoring of temperature information.
研究领域:
材料科学
·
生物医学工程
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）