The process of biomineralization in dentin and bone tissue repair has been extensively studied. In vitro, biomineralization can be stimulated via a polymer-induced liquid precursor (PILP) process. Guided bone regeneration using a barrier membrane and bone substitute materials is widely used in implantology in cases where there is insufficient bone volume. Herein, we applied a homologous PILP processes to fabricate collagen films with a varying degree of mineralization and tested their performance. The results showed that the prepared biomineralized membranes are biocompatible, have a high stress strength and can promote MC3T3-e1 cell proliferation . This indicated that the membranes can be potentially applied in guided bone regeneration, with membranes containing a higher degree of mineralization achieving the best results.
Xiang Tao,Mengjie Wei,Xianfei Hu,Yong Tang,Wei Wei,Jingcheng Liu,Xiaojie Li
Hyperbranched epoxy resins are efficient modifiers for epoxy resins but still require simultaneous improvements in terms of thermomechanical/mechanical properties and thermal stability. Herein, a novel resveratrol-based hyperbranched polyether epoxy resin (HBPEER) was designed for all-purpose epoxy resin modification. To this end, hyperbranched polyether with terminal phenolic hydroxyl groups was first synthesized from commercially available 1,6-dibromohexane (A 2 -type monomer) and resveratrol (B'B 2 -type monomer). Surface modification with epichlorohydrin was afterward implemented to produce hyperbranched polyether with terminal epoxy groups (HBPEER). Next, various HBPEER-modified epoxy thermosets were prepared and characterized. The results suggested that compared to the neat diglycidyl ether of bisphenol A (DGEBA) thermoset, the 6 wt% HBPEER-modified epoxy thermoset showed an increase in impact strength, elongation at break, critical stress intensity factor (K IC ), critical crack propagation energy release rate (G IC ), flexural strength, tensile strength, storage modulus, glass transition temperature (T g ), and initial thermal decomposition temperature (T d5% ) by 69.6 %, 87.0 %, 32.0 %, 68.2 %, 29.3 %, 37.0 %, 8.1 %, 3.5 %, and 1.6 % respectively. Moreover, the dielectric constant and loss of 6 wt% HBPEER-modified epoxy thermoset decreased by 16.2 % and 16.5 %, respectively. Such comprehensive performance modifications were caused by the combined effects of crosslink density improvement, efficient intramolecular cavity, rigid stilbene units, and flexible aliphatic backbone of HBPEER.
危险品化学品经营许可证（带存储）