Chemical Engineering Journal Advances
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2025
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IF 7.1
Jisheng Li,Xu Zhao,Yuheng Fan,Changyu Sun,Yufeng Hu,Laiyong Zhang,Fayan Zhu,Jilong Han
Boric acid, a vital chemical in industries, agriculture, and high-tech fields, is primarily extracted from Salt Lake brines via liquid-liquid extraction. The efficiency differences between alcohols remain unclear. This study investigates boric acid extraction using isobutanol and isooctanol, combining experiments and theoretical calculations to reveal microscopic mechanisms. Experiments show that under low pH, multi-stage extraction significantly impacts efficiency, with isooctanol outperforming isobutanol. Computational results reveal that isooctanol’s hydroxyl oxygen has a more negative electrostatic potential, forming stronger, more stable hydrogen bonds with boric acid. Isooctanol also exhibits shorter interaction distances and higher interaction energy with boric acid compared to isobutanol. The study concludes that isooctanol’s superior performance is due to its ability to form more and longer-lived hydrogen bonds. This work provides new theoretical insights into boric acid extraction and aids in designing efficient extractants.
研究领域:
化学工程
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理论计算
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高影响因子
RSC Advances
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2018
·Vol. 8
·期 18
·10009-10016
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IF 2.936
Zichen Xu,Guoying Zhao,Latif Ullah,Meng Wang,Aoyun Wang,Yanqiang Zhang,Suojiang Zhang
A facile strategy for the synthesis of acidic ionic liquid based UiO-67 type MOFs was developed in this study. Brønsted acids (H2SO4, CF3SO3H and hifpOSO3H (hexafluoroisopropyl sulfuric acid)) were introduced into UiO-67–bpy (bpy = 2,2′-bipyridine-5,5′-dicarboxylic acid) frameworks by reacting with bipyridyl nitrogen to introduce the properties of an acidic ionic liquid into the frameworks. The prepared catalysts, denoted as UiO-67–HSO4, UiO-67–CF3SO3 and UiO-67–hifpOSO3, were characterized by XRD, SEM, FT-IR, EA, TGA and N2 adsorption–desorption studies. The relatively high surface area was still maintained and acidic active groups were uniformly dispersed in the frameworks. The catalytic performance of UiO-67–HSO4, UiO-67–CF3SO3 and UiO-67–hifpOSO3 was evaluated by the esterification of acetic acid with isooctyl alcohol. The prepared catalysts showed good catalytic activities in the esterification, of which UiO-67–CF3SO3 gave the maximum isooctyl alcohol conversion of 98.6% under optimized conditions. The catalyst could be reused five times without a significant decrease in the conversion of isooctyl alcohol, and almost no active species were leached, indicating the excellent stability and reusability of the catalyst. Our study provides one effective way to synthesize heterogeneous acidic ionic liquid catalysts consisting of isolated, well defined acidic groups that will probably attract interest in acid catalyst chemistry.
研究领域:
材料化学
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催化化学
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2021
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IF 7.312
Yaxing Han,Ji Chen,Yuefeng Deng,Tianchi Liu,Hailian Li,Deqian Li
The current separation technique of ion-adsorption high yttrium (Y) rare earth ore (high-yttrium ore) using 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester (P507) and naphthenic acid (NA) has been confronted with low separation efficiency and high acid consumption. This is a consequence of the low selectivity and the difficulty of complete stripping of heavy rare earths (HREEs). Therefore, an innovative separation technique of high-yttrium ore was proposed. The leachate of high-yttrium ore was firstly divided into Erbium (Er) / Thulium (Tm) groups with P507-isooctanol followed by separating Y (III) from the high Y-enrichment of Er (III) group with sec -octylphenoxy acetic acid (CA12)-tri- n -butyl phosphate (TBP). The basic thermodynamics experiments and cascade extraction simulations were conducted to verify the feasibility of this technology. The results show that P507-15vol% isooctanol is superior to P507 in both stripping ability and separation selectivity of HREEs. The first cascade extraction for Er (III) / Tm (III) grouping with P507-15vol% isooctanol was simulated successfully, reducing acid consumption but obtaining high purity products. In theory, the second cascade extraction simulation designed for separating Y (III) with CA12-TBP could not only improve the separation ability between Y (III) and light rare earths (LREEs) but also shorten the extraction stages and reduce the production costs. All these results revealed that this two-step separation process probably provided a promising application prospect for separating high-yttrium ore.
研究领域:
冶金工程
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稀土化学
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分离科学与技术
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资源加工工程
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湿法冶金
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萃取分离
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2025
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IF 6.2
Huifang Yang,Wenhao Yang,Yuting Zhang,Ramy M. Khoder,Shanbai Xiong,Yueqi An
This study analyzed the changes in key aroma compounds in grass carp fillets during cold storage using aroma extract dilution analysis, odor activity values, and aroma recombination. A total of 11, 13, and 14 volatile compounds were recombined to construct recombination models representing the odor of fillets at 0, 3, and 7 days of cold storage, respectively. The key aroma compounds in fresh fillets included hexanal, (Z)-4-heptenal, nonanal, (E,E)-2,4-octadienal, (E,Z)-2,6-nonadienal, (E)-2-nonenal, decanal, (E)-2-decenal, (E,E)-2,4-decadienal, 1-octen-3-ol, and 2,3-pentanedione. Moreover, (E)-2-octenal, 2-cyclopenten-1-one, γ-dodecalactone, and octanoic acid became the key aroma compounds after 3 and 7 days of refrigeration, respectively. (Z)-4-Heptenal, (E,Z)-2,6-nonadienal, (E)-2-nonenal, decanal, and (E,E)-2,4-decadienal indicated the deterioration in flavor quality of fillets, which rose by 38.29 μg/kg (0–7 days). This study clarifies the key aroma compounds and characteristic compounds responsible for odor changes during the cold storage of fillets, establishing a basis for future improvement in odor quality during cold storage.
研究领域:
食品科学
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分析化学
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DOI
PubMed
高影响因子
Scientific Reports
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2024
·Vol. 14
·期 1
·1-11
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IF 3.8
Chu Yajing,Ge Dianlong,Zhou Jijuan,Liu Yue,Zheng Xiangxue,Liu Wenting,Ke Li,Lu Yan,Chu Yannan
Characteristic volatile organic compounds (VOCs) are anticipated to be used for the identification of lung cancer cells. However, to date, consistent biomarkers of VOCs in lung cancer cells have not been obtained through direct comparison between cancer and healthy groups. In this study, we regulated the glycolysis, a common metabolic process in cancer cells, and employed solid phase microextraction gas chromatography mass spectrometry (SPME–GC–MS) combined with untargeted analysis to identify the characteristic VOCs shared by cancer cells. The VOCs released by three types of lung cancer cells (A549, PC-9, NCI-H460) and one normal lung epithelial cell (BEAS-2B) were detected using SPME–GC–MS, both in their resting state and after treatment with glycolysis inhibitors (2-Deoxy- d -glucose, 2-DG/3-Bromopyruvic acid, 3-BrPA). Untargeted analysis methods were employed to compare the VOC profiles between each type of cancer cell and normal cells before and after glycolysis regulation. Our findings revealed that compared to normal cells, the three types of lung cancer cells exhibited three common differential VOCs in their resting state: ethyl propionate, acetoin, and 3-decen-5-one. Furthermore, under glycolysis control, a single common differential VOC—acetoin was identified. Notably, acetoin levels increased by 2.60–3.29-fold in all three lung cancer cell lines upon the application of glycolysis inhibitors while remaining relatively stable in normal cells. To further elucidate the formation mechanism of acetoin, we investigated its production by blocking glutaminolysis. This interdisciplinary approach combining metabolic biochemistry with MS analysis through interventional synthetic VOCs holds great potential for revolutionizing the identification of lung cancer cells and paving the way for novel cytological examination techniques.
研究领域:
生物化学
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医学诊断
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代谢组学
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DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2024
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IF 5.3
Zongpeng Liu,Shaojian Hu,Yuning Zhang,Bencheng Wu,Jianhua Zhu
Synthetic esters are expected to have broad application prospects in the high-end lubrication sectors owing to their fascinating custom-tailored properties. Herein, we synthesized a novel complex polyolester (CPE) via a stepwise esterification procedure using stannous oxide as a heterogeneous catalyst. Response surface methodology coupled with the Box–Behnken design (BBD-RSM) was employed to optimize the experimental parameters and elucidate the interactions among the operating variables on the low-temperature fluidity of CPE. The optimization results indicated that the lowest pour point (−42 °C) could be obtained under the catalyst dosage of 1.2 wt%, the first step reaction temperature of 164 °C, the first step reaction time of 100 min, and the second step reaction temperature of 178 °C. Particularly, there is a significant interactive effect between the catalyst dosage and the second step reaction temperature. Followed by the molecular distillation of the crude ester prepared under the optimal conditions, the refining results revealed that the non-ideal components had been effectively removed and the total acid number of the final product was substantially reduced to below 0.1 mg KOH/g. The molecular structures of the as-synthesized esters were confirmed by FT-IR, NMR, GPC, ESI–MS, and TGA characterization and their physicochemical and tribological properties were also evaluated according to standard methods. In view of the unique molecular structural design, the developed CPE displayed plentiful prominent technological specificities, which makes it plausible to be served as a potential high-performance base stock. Therefore, the findings of this study may provide some valuable insights for expanding the application scope of synthetic esters into various special industrial scenarios.
研究领域:
化学工程
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材料科学
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润滑技术
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DOI
高影响因子
Metals
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2024
·Vol. 14
·期 3
·345
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IF 2.6
Xiaoqin Wang,Zhulin Zhou,Xuting Si,Youcai Lu,Qingchao Liu
In order to overcome the interface emulsification problem of TBP-FeCl3systems and the instability of β-diketone systems in high-concentration alkaline medium, it is necessary to design and synthesize some new extractants. By introducing amino groups into a phosphorus extractant, a new 2-ethylhexyl hydrogen {[bis(2-ethylhexyl)amino]methyl} phosphonate acid (HA) extractant was synthesized. In this study, an efficient method of recovering lithium from the effluent of spent lithium-ion batteries (LIBs) is proposed. Experiments were conducted to assess the influential factors in lithium recovery, including the solution pH, saponification degree, extractant concentration, and phase ratio. Over 95% of lithium in the effluent was extracted into the organic phase, and nearly all lithium in the organic phase could be stripped into the aqueous phase using a 3 mol/L HCl solution. There was no significant decrease in extraction capacity after 10 cycles. The experimental results indicated that the extraction mechanism was a cation exchange process, and the extractive complex was proposed as LiA. Importantly, after three months of stable operation, the process demonstrated excellent stability and extraction efficiency, with rapid phase separation and a clear interface. This study offers an efficient, cost-effective, and environmentally friendly method for lithium extraction from the effluent of spent LIBs.
研究领域:
化学工程
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环境科学
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DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2024
·
IF 7
Jieyao Yu,Jingzhe Li,Zhi Lin,Yin Zhu,Zhihui Feng,Dejiang Ni,Shengchun Zeng,Xuehong Zeng,Yijun Wang,Jingming Ning,Liang Zhang,Xiaochun Wan,Xiaoting Zhai
As a kind of green tea with unique multiple baking processes, the flavor code of Lu’an Guapian (LAGP) has recently been revealed. To improve and stabilize the quality of LAGP, further insight into the dynamic changes in odorants during the whole processing is required. In this study, 50 odorants were identified in processing tea leaves, 14 of which were selected for absolute quantification to profile the effect of processes. The results showed that spreading is crucial for key aroma generation and accumulation, while these odorants undergo significant changes at the deep baking stage. By adjusting the conditions of the spreading and deep baking, it was found that low-temperature (4 °C) spreading for 6 h and low-temperature with long-time baking (final leaf temperature: 102 °C, 45 min) could improve the overall aroma quality. These results provide a new direction for enhancing the quality of LAGP green tea.
研究领域:
食品科学
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农学
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茶学
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
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2024
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IF 6.7
Jijuan Zhou,Dianlong Ge,Yue Liu,Yajing Chu,Xiangxue Zheng,Yan Lu,Yannan Chu
Cellular volatile organic compound (VOC) detection is crucial for studying lung cancer biomarkers. However, the reported VOC biomarkers from the same cell line seem to be inconsistent across different research groups. It is possibly related to the variation in culture media, and the result obtained by a conventional single medium approach (SMA) depends on what medium is used in the cell experiment. This study proposes a multiple media approach (MMA) to investigate reproducible characteristic VOCs of lung cancer cells. Using solid-phase microextraction–gas chromatography–mass spectrometry (SPME-GC-MS) in combination with untargeted analysis, we conducted two independently repetitive experiments to compare lung cancer cells (A549) and normal lung cells (BEAS-2B) under three culture media conditions (RPMI 1640, DMEM, and Ham’s F12). Both experiments indicated that, compared with 62–96 VOCs obtained by the SMA, only two VOCs (3-methyl-1-butanol and 2-methyl-1-butanol) were reproducibly achieved by the MMA. Moreover, their concentrations were significantly lower in lung cancer cells than in normal cells. Further targeted analysis confirmed the downregulation trend of both VOCs in subcutaneous and primary tumor tissues from the lung cancer model mouse. The present work demonstrated that the MMA cell experiment, just like the multicenter trials for cell lines, can facilitate the discovery of reproducible characteristic VOCs. This provides a cellular experimental basis and scientific evidence for lung cancer biomarker investigation and even breath biopsy technique development.
研究领域:
医学
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分析化学
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肿瘤学
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DOI
PubMed
高影响因子
International Journal of Coal Preparation and Utilization
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2024
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IF 2
Canjin Luo,Lei Tian,Zihao Zhao,Hongli Yang,Minqiang Fan
A gravity – flotation coupled separator with up-flow feeding and dual-concentrate was developed to improve the recovery and selectivity in coarse coal slime separation. The separator combines flotation, cyclone separation, and gravity sedimentation. The optimal separation performance was achieved under the following conditions: slurry concentration = 100 g/L, feed flow rate = 4.411 m3/h, circulating rate = 3.125 m3/h, fifigfeeding air flow rate = 2 m3/h, frother dosage = 150 g/t and collector dosage = 1500 g/t. Two concentrates were obtained with ash contents of 7.48% and 11.56%. The partition coefficients of the 0.75–1 and 0.5–0.75 mm fractions were 88.42% and 95.92%, respectively, indicating the satisfactory recovery of coarse particles. The ash content in the tailings was 66.08%, indicating good selectivity. The diverging flow under the froth layer produced a coarse concentrate, which improved the recovery of the concentrate and reduced the flotation concentrate ash content. The total recovery of the concentrate blended with the + 0.25 mm fraction of diverging flow was 84.00%. Both up-flow and cyclone separation are beneficial for coarse particle recovery. The static separation cone is instrumental in improving the separation effect. Therefore, this wide-sized coal-slime separator facilitates the effective separation of both coarse and fine particles.
研究领域:
矿物加工工程
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煤炭科学与技术
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DOI
高影响因子
FOOD CHEMISTRY
·
2025
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IF 9.8
Yanyan Cao,Meng Tao,Anan Xu,Zheng Tu,Shanshan Wang,Qinyan Yu,Sixu Li,Zhengquan Liu
Black tea contains sweet aroma compounds (SACs) with sweetening potential. However, a systematic understanding of their composition, enhancing effects, and underlying mechanisms is lacking. This study identified 14 key SACs in global sweet-aroma black teas using headspace solid-phase microextraction coupled with gas chromatography–mass spectrometry. Electronic tongue and sensory validation confirmed their sweetness-enhancing effects in a sugar-free black tea beverage and revealed their inherent taste properties (sweetness, astringency, pungency, and cooling). Molecular docking and dynamics simulation elucidated the stable bindings of T1R2/T1R3-benzeneacetaldehyde/ β -damascenone, α -amylase-benzeneacetaldehyde, TRPV1-geraniol, and TRPM8-methyl salicylate, mediated by hydrogen bonding and hydrophobic interactions. These protein-ligand complexes were proposed to modulate sweetness, sweet aftertaste, heat-evoked sweetness, and cooling-enhanced sweetness, respectively. Consequently, this study demonstrates that SACs enhance sweetness through cross-modal interactions and inherent taste properties, providing novel mechanistic insights and actionable strategies for flavor optimization in tea beverages and other food products.
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Erkang Li,Jingwei Cao,Yujie Zhen,Jiajun Wei,Yingmin Yu
Wastewater from coking and pharmaceutical processes often contain a significant amount of 2-methylpyridine, which forms an azeotropic mixture with water. Effectively and cleanly separating 2-methylpyridine from wastewater while conserving energy and obtaining high purity products is an urgent challenge. In this study, ternary liquid-liquid equilibrium (LLE) data for the extraction of 2-methylpyridine from wastewater were measured using three distinct solvents at temperatures of 303.2 K, 313.2 K, and 323.2 K. The obtained ternary data were subsequently correlated with thermodynamic models (NRTL and UNIQUAC) to get relevant binary interaction parameters, bridging a gap in Aspen Plus simulations of 2-methylpyridine separation by octanol solvents. Furthermore, the GUI tool was used to validate these parameters and the results confirmed the reliability of the obtained parameters. It was observed that as the temperature increased, the extraction performance of all systems decreased, indicating that elevated temperature are not conducive to the extraction process. Among the various components, iso-octanol showed the highest separation factor indicating better extraction efficiency of 2-methylpyridine. Additionally, this study integrated quantum chemical calculations to reveal the interaction mechanisms between different solvents, 2-methylpyridine, and water at the microscopic level. The computational results indicated that iso-octanol exhibited the most robust binding affinity with 2-methylpyridine, suggesting that iso-octanol has more excellent extraction properties.
研究领域:
化学工程
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环境科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）