JOURNAL OF FOOD ENGINEERING
·
2025
·
IF 5.8
Yuan Tao,Bowen Yan,Nana Zhang,Jianxin Zhao,Wei Chen,Daming Fan
Microwave vacuum evaporation (MVE) is a promising alternative over traditional vacuum evaporation, offering rapid evaporation rates and high efficiency. This study investigated the MVE processes and the resulting quality of sugar solutions under varying microwave power densities (10–50 W/g) and vacuum levels (40–80 kPa). The results indicated that a moderate microwave power density (∼30 W/g in this study) was optimal for MVE, balancing both evaporation efficiency and sugar quality. Furthermore, the dielectric properties of the sugar solutions during MVE (over the temperature range of approximately 25-110°C) exhibited a time-dependent decrease in the dielectric constant (ε′), whereas both the dielectric loss factor (ε′′) and loss tangent (tanδε) initially decreased before increasing. Similar values of ε′′ and tanδε were observed for sugar solutions evaporated at high power densities, accounting for the phenomenon of saturated evaporation. The penetration depth, reflection loss, and relative input impedance results indicated that the 4 mm-thick sugar solutions exhibited good microwave absorption during the MVE, except at the initial and final stages, confirming the feasibility of utilizing a liquid film configuration in MVE applications. In conclusion, the analysis of dielectric and microwave absorption properties offers a robust approach for optimizing the MVE process, facilitating the production of high-quality sugars.
研究领域:
食品科学
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化学工程
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电磁学
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工艺优化
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2024
·
IF 5.8
Xi Luo,Han-Yao Sun,Shang-Yu Lu,Yan Zhou,Zi-Qing Xu,Nan Zhong,Yi-Shi Lu,Shou-Ju Wang,Hai-Bin Shi,Wei Tian
Microwave ablation (MWA) is recognized as a novel treatment modality that can kill tumor cells by heating the ions and polar molecules in these cells through high-speed rotation and friction. However, the size and location of the tumor affect the effective ablation range of microwave hyperthermia, resulting in residual tumor tissue and a high recurrence rate. Due to their tunable porous structure and high specific surface area, metal–organic frameworks (MOFs) can serve as microwave sensitizers, promoting microwave energy conversion owing to ion collisions in the porous structure of the MOFs. Moreover, iron-based compounds are known to possess peroxidase-like catalytic activity. Therefore, Fe-doped Cu bimetallic MOFs (FCMs) were prepared through a hydrothermal process. These FCM nanoparticles not only increased the efficiency of microwave-thermal energy conversion as microwave sensitizers but also promoted the generation of reactive oxygen species (ROS) by consuming glutathione (GSH) and promoted the Fenton reaction to enhance microwave dynamic therapy (MDT). The in vitro and in vivo results showed that the combination of MWA and MDT treatment effectively destroyed tumor tissues via microwave irradiation without inducing significant side effects on normal tissues. This study provides a new approach for the combined application of MOFs and microwave ablation, demonstrating excellent potential for future applications.
研究领域:
材料科学
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癌症治疗
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生物医学工程
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Biomaterials Science
·
2025
·
IF 5.7
Yu Zhang,Man Shu,Xiao Chu,Jielong Zhou,Qiao Zhou,Guoqing Zhong,Renshan Li,Yue He,Guiquan Zhang,Ziyang Xu,Teliang Lu,Mei Li,Xiongfa Ji,Anjun Qin,Jin Ke,Zhidan Tan
Osteosarcoma (OS) is an aggressive malignant tumor with high recurrence and metastatic potential, primarily affecting adolescents. Despite the standard clinical "sandwich" treatment regimen, patient survival rates have remained stagnant. Microwave ablation (MWA), known for its rapid heating and strong tissue penetration, has emerged as a viable therapeutic strategy for bone tumors. However, MWA poses challenges, particularly the potential for iatrogenic damage to adjacent healthy tissues and the concern that inappropriate energy delivery parameters may paradoxically stimulate neoplastic progression. In this study, microwave-triggered organic nanoparticles, termed ATT, were synthesized via a spontaneous [2+2] cycloaddition-cycloreversion (CA-CR) reaction. Findings from cell-based assays and animal studies indicated that ATT effectively generated reactive oxygen species (ROS) and produced heat under microwave (MW) irradiation, achieving a remarkable tumor inhibition rate of 95%. Owing to its unique donor-acceptor (D-A) structure and twisted molecular configuration, ATT facilitates efficient charge transfer under MW irradiation. The process generates electron-hole pairs, enhancing ROS production and enabling effective microwave dynamic therapy (MDT) effect. Moreover, ATT acts as a polar molecule that efficiently absorbs MW and generates heat through resonance, thereby potentiating the therapeutic performance of microwave thermal therapy (MTT). This study presents a novel microwave-triggered organic nanomaterial that integrates MTT and MDT, offering a prospective therapeutic intervention for OS.
研究领域:
肿瘤学
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纳米医学
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生物有机化学
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治疗放射学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Crystals
·
2023
·Vol. 13
·期 9
·1296
·
IF 2.7
Yan Wang,Jiajing Li,Haipeng Zhu,Qilei Wang,Tulai Sun,Tao Ni,Yanghong Lin,Yu Liu,Minmin Mao,Ji Hu,Bing Liu,Hadi Barzegar Bafrooei,Zhongyan Ma,Yingjie Ren,Feng Shi,Ehsan Taheri-Nassaj,Dawei Wang,Kaixin Song
Mg2SiO4and MgSiO3ceramics with superior microwave dielectric properties are considered to be promising candidates for 5G applications. However, a slight deviation from the stoichiometric Mg/Si ratio will significantly influence their microwave dielectric properties, which will hinder their practical applications. In this work, thexMgO-SiO2(x= 1~2) ceramics were synthesized by a solid-state reaction method. The influence of the Mg/Si ratioxon the crystalline phase, microstructure, and microwave dielectric properties was investigated through X-ray diffraction (XRD), a scanning electron microscope (SEM), and the resonant cavity method. The XRD patterns revealed the coexistence of Mg2SiO4and MgSiO3within thexrange of 1~2, which was further demonstrated by the energy-dispersive X-ray spectra. The SEM images show a typical polycrystalline morphology of ceramics with an inhomogeneous grain size distribution. It is found that the microwave dielectric properties fluctuate at both sides of thexrange while those remain relatively stable with minor changes at the intermediate components, indicating an obvious low composition dependence helpful for practical applications. Further, a demonstrator of a microstrip patch antenna for 5G applications using the 1.5MgO-SiO2ceramic was designed and fabricated, and a return loss of −16.2 dB was demonstrated, which demonstrated the potential applications.Keywords:MgO-SiO2systems;5G application;microwave dielectric ceramics;phase composition
研究领域:
材料科学
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电子工程
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产品关联
DOI
高影响因子
JOURNAL OF CONTROLLED RELEASE
·
2023
·
IF 10.8
Yifu Feng,Qian Chen,Chong Jin,Yanyun Ruan,Qi Chen,Weidong Lin,Chumeng Zhu,Tinglin Zhang,Yang Zhang,Jie Gao,Jinggang Mo
Percutaneous microwave ablation (PMA) is a thermoablative method used as a minimally invasive treatment for liver cancer. However, the application of PMA is limited by its insufficient ROS generation efficiency and thermal effects. Herein, a new microwave-activated Cu-doped zirconium metal-organic framework (MOF) (Cu Zr MOF) used for enhanced PMA has a significantly improved microwave sensitizing effect. Owing to the strong inelastic collisions between ions confined in numerous micropores, Cu Zr MOF has strong microwave sensitivity and high thermal conversion efficiency, which can significantly improve microwave thermal therapy (MTT). Moreover, because of the existence of Cu 2+ ions, a further benefit of Cu Zr MOF is their Fenton-like activity, in particular, microwaves used as an excitation source for microwave dynamic therapy (MDT) can improve the Fenton-like reaction to maximize the synergistic effectiveness of cancer therapy. Importantly, Cu Zr MOF can inhibit the production of heat shock proteins (HSPs) by producing abundant ROS to enhance tumor destruction. Mechanistically, we found that Cu Zr MOF + MW treatment modulates ferroptosis-mediated tumor cell death by targeting the HMOX1/GPX4 axis. In summary, this study develops a novel Cu Zr MOF microwave sensitizer with great potential for synergistic treatment of liver cancer by MTT and MDT.
研究领域:
肿瘤学
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材料科学
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治疗工程
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癌症生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Mengmeng Zhang,Caiyun Wu,Hexin Zhang,Nana Yang,Chengxin Wang,Xiaolan Jike,Ting Zhang,Hongjie Lei
The objective of this study was to evaluate the impacts of different drying technologies including microwave drying (MD), vacuum microwave drying (VMD), sun drying (SD), vacuum drying (VD), hot air drying (HAD), and vacuum freeze drying (VFD) on the physical characteristics, nutritional properties and antioxidant capacities of kiwifruit pomace in order to realize by-product utilization and improve energy efficiency. Results showed that both MD and VMD significantly reduced drying time by >94.6%, compared to traditional thermal drying which took 14–48 h. MD exhibited the highest content of soluble dietary fiber (9.5%) and the lowest energy consumption. Furthermore, VMD resulted in the highest content of vitamin C (198.78 mg/100 g) and reducing sugar (73.78%), and the antioxidant capacities ranked only second to VFD. Given the financial advantages and product quality , VMD was suggested to be advantageous technology in actual industrial production.
研究领域:
食品科学
·
营养学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2017
·Vol. 52
·期 23
·13522-13532
·
IF 2.599
Fan Lidan,Zhou Yuming,He Man,Tong Yuan,Zhong Xi,Fang Jiasheng,Bu Xiaohai
Boron nitride quantum dots (BNQDs), as promising metal-free quantum dots with unique photoelectric properties, have been controllably fabricated by a facile and high-efficiency microwave irradiation technique in this work. Though a number of attempts have been reported so far, it remains challenging to explore an effective approach to synthesize high-quality BNQDs with uniform size, well dispersion and high quantum yield (QY). Microwave irradiation strategy is identified as an advanced and beneficial method not only for high-efficiency energy inputting but also time-saving in comparison with the reported solvothermal process. Encouragingly, the particle size and QY of BNQDs can be well controlled by adjusting microwave reaction temperature as well as duration time. The average diameter of the as-prepared blue luminescent BNQDs ranges from 1.98 to 7.05 nm with QY up to 23.44%. Furthermore, attributed to the unique nanostructure, quantum confinement effect, and high dielectric loss, the as-prepared BNQDs exhibits an optimal reflection loss of −19.6 dB at 8.9 GHz with a broad effective absorption bandwidth of 5.02 GHz in the frequency range of 2–18 GHz, demonstrating as potential microwave absorption material in electromagnetic interference field.
研究领域:
材料科学
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纳米技术
·
电磁工程
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Ya-Ru Hou,Yi-Lin Zhan,Zhe-Kun Xu,Xiao-Gang Chen,Zhong-Xia Wang,Hui-Peng Lv
Dielectric switch materials are widely used in network communication, data storage, and industry control, among which molecule-based hybrid perovskites have aroused extensive interest due to simple fabrication, lightweight, mechanical flexibility, and phase transition characteristics. However, current research on molecular materials mainly focuses on low-frequency ranges (1 kHz to 1 MHz), with limited exploration of high-frequency switching, which represents a development trend of electronics. Herein, we have synthesized three molecular perovskites, NH(CH3)3CdCl3, (CH3)4NCdCl3, and [(CH3)3NCH2Cl]CdCl3 (TMCM-CdCl3), and studied their phase transition and dielectric properties in ultrawide range from 1 kHz to 18 GHz. They undergo phase transitions at 341, 374, 402, and 400 K, respectively. Notably, TMCM-CdCl3 exhibited distinct dielectric anomalies in the whole studied frequency range, especially high-frequency dielectric switching in 12–18 GHz. NH(CH3)3CdCl3 and (CH3)4NCdCl3 only possess dielectric switching or no anomalies in low frequency bands. Dielectric loss of TMCM-CdCl3 exhibits step-like elevation across phase transition, which endows it with “on/off” switchable microwave attenuation capability (reflection loss of −42.4 dB and effective absorption bandwidth of 5.7 GHz in the on state) at a thickness of 1.6 mm. This work highlights the high-frequency dielectric switching of molecular hybrid perovskites and provides insights into functionality explorations of molecule-based materials.
研究领域:
材料科学
·
凝聚态物理
·
功能材料
·
电子学
·
介电材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2015
·
IF 4.169
Zaizhi Liu,Huiyan Gu,Lei Yang
Ionic liquids/lithium salts solvent system was successfully introduced into the separation technique for the preparation of two coumarins (aesculin and aesculetin) from Cortex fraxini. Ionic liquids/lithium salts based microwave irradiation pretreatment followed by ultrasound-microwave synergy extraction (ILSMP-UMSE) procedure was developed and optimized for the sufficient extraction of these two analytes. Several variables which can potentially influence the extraction yields, including pretreatment time and temperature, [C 4 mim]Br concentration, LiAc content, ultrasound-microwave synergy extraction (UMSE) time, liquid–solid ratio, and UMSE power were optimized by Plackett–Burman design. Among seven variables, UMSE time, liquid–solid ratio, and UMSE power were the statistically significant variables and these three factors were further optimized by Box–Behnken design to predict optimal extraction conditions and find out operability ranges with maximum extraction yields. Under optimum operating conditions, ILSMP-UMSE showed higher extraction yields of two target compounds than those obtained by reference extraction solvents. Method validation studies also evidenced that ILSMP-UMSE is credible for the preparation of two coumarins from Cortex fraxini. This study is indicative of the proposed procedure that has huge application prospects for the preparation of natural products from plant materials.
研究领域:
植物化学
·
天然产物分离
·
药用植物学
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 16
·9362
·
IF 6.208
Chenzhi Zhang,Dashuang Wang,Lichao Dong,Kailin Li,Yifan Zhang,Pingan Yang,Shuang Yi,Xingjian Dai,Changqing Yin,Zhilan Du,Xinfang Zhang,Quan Zhou,Zhiyu Yi,Jinsong Rao,Yuxin Zhang
A neoteric round sieve diatomite (De) decorated with sea-urchin-like alpha-type iron trioxide (α-Fe2O3) synthetics was prepared by the hydrothermal method and further calcination. The results of the electromagnetic (EM) parameters of α-Fe2O3-decorated De (α-Fe2O3@D) showed that the minimum reflection loss (RLmin) of α-Fe2O3@D could reach −54.2 dB at 11.52 GHz and the matched absorber thickness was 3 mm. The frequency bandwidth corresponding to the microwave RL value below −20 dB was up to 8.24 GHz (9.76–18 GHz). This indicates that α-Fe2O3@D composite can be a lightweight and stable material; because of the low density of De (1.9–2.3 g/cm3), the density of α-Fe2O3@D composite material is lower than that of α-Fe2O3(5.18 g/cm3). We found that the combination of the magnetic loss of sea-urchin-like α-Fe2O3and the dielectric loss of De has the most dominant role in electromagnetic wave absorption and loss. We focused on comparing the absorbing properties before and after the formation of sea-urchin-like α-Fe2O3and explain in detail the effects of the structure and crystal shape of this novel composite on the absorbing properties.Keywords:diatomite;α-Fe2O3;microwave absorption
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Yuting Cao,Yan Zhou,Jinbin Pan,Xinyu Zhong,Jianmin Ding,Xiang Jing,Shao-Kai Sun
The minimal invasive percutaneous microwave ablation (MWA) combined with immunotherapy is a promising technique in clinic for the treatment of primary and metastatic tumors. However, elaborate encapsulation carrier designs, complex cellular engineering, and poor applicability are the vexing problems difficult to solve currently. Herein, a general strategy was proposed for the design of an injectable microwave-sensitive immune hydrogel for combined MWA and immunotherapy in vivo for the first time. The mix-and-use hydrogel composed Food and Drug Administration (FDA)-approved components were fabricated by introducing various immunostimulants regardless of hydrophilicity and hydrophobicity into the alginate (ALG)-Ca 2+ hydrogel. As a proof of concept, an immunoadjuvant (R837) was employed to synthesize the R837-ALG-hydrogel for systematic studies. This immune hydrogel owns ultra-facile synthesis process, good microwave-sensitivity, adjuvant encapsulation efficiency of nearly 100%, good biocompatibility and syringeability, and large-scale production capability, which could be easily injected into the primary tumor for enhancing MWA. Moreover, the loaded R837 could motivate in situ vaccination by making the utmost of the tumor-associated antigens released after MWA, thereby inducing the robust tumor-specific antitumor immunity to suppress the distant metastatic tumor in vivo. The proposed injectable microwave-sensitive immune hydrogel paves a facile but general avenue with great clinical translation potential for the minimal invasive personalized oncotherapy.
研究领域:
肿瘤学
·
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2024
·
IF 7
Xingwei Wang,Heping Cui,Xiaoming Zhang,Jingyang Yu,Shuqin Xia,Chi-Tang Ho
Directional and rapid formation of the Amadori rearrangement product (ARP) from the glutamic acid and xylose was achieved through intermittent microwave heating. The yield of ARP reached 58.09 % by subjecting the system to intermittent microwave heating at a power density of 10 W/g for 14 min. Dehydration rate and microwave effects were found to be key factors to optimize the conditions for directional and rapid preparation of the ARP. Through a comprehensive analysis of the ARP degradation and further browning under both conductive and microwave thermal processing, it was observed that microwave processing significantly accelerated the browning degree of systems, leading to a tenfold reduction in the heating time required for browning. This research presented a promising avenue for the development of novel and expedited methods for the production of ARP and highlighted the potential of ARP in enhancing color quality in fast-cooking applications utilizing microwave.
研究领域:
食品科学
·
化学工程
·
微波技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）