Materials
·
2019
·Vol. 12
·期 11
·1769
·
IF 2.972
Wenchao Chi,Jiawei Zou,Fanrong Ai,Yanjun Lin,Wenchao Li,Chuanliang Cao,Kang Yang,Kui Zhou
Copper is an indispensable micronutrient in human health, which has important effects on the promotion of angiogenesis and thus contributes to bone formation and antimicrobial activity. We used ion exchange and pneumatic printing methods to prepare hydroxyapatite (HA) microspheres with different copper content. The microspheres were characterized by scanning electron microscope (SEM), X-ray diffractometry (XRD) and X-Ray photoelectron spectroscopy (XPS). Considering the resistance of hydroxyapatite to biodegradation in vivo, the degradation rate of microspheres in modified simulated body fluids was studied. In addition, cell proliferation and antibacterial experiments were carried out to study the biological properties of microspheres. HA-1.5MCu microbeads treated by 1.5 mol/L CuSO4curing solution have good performance on degradation, antibacterial properties and cell survival rate on day 7. The results showed that HA-1.5MCu microbeads may be used as a good repair material for bone defects.Keywords:hydroxyapatite;microbeads;copper;biological performance
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD ENGINEERING
·
2020
·
IF 4.499
Gaoshang Wang,Zhili Wan,Xiaoquan Yang
It is a challenge to pasteurize higher-viscosity and heat-sensitive foodstuffs via traditional convective heat transfer. Herein, we demonstrate the potential application of magnetic induction heating (MIH) as a novel uniform heating method applied in the pasteurization of liquid whole eggs (LWEs). Upon exposure to an alternating magnetic field (AMF), the magnetic microbeads with a large size (50 μm) generated heat via the magnetic hysteresis effect, providing accurate and homogeneous heating due to the high specific absorption rate (SAR) of 3108.4 ± 30.6 W/(g Fe) and a homogeneous particle dispersion in high-viscosity food media. A 7.6 log reduction of Salmonella Enteritidis could be achieved in LWEs treated by MIH at 68 °C and 60 s, which was comparable to the inactivation performance of the convective heating protocol at 60 °C and 210 s (6.0 log reduction). Importantly, MIH showed a critical temperature-time regime to prevent the coagulation of egg proteins, thus maintaining the quality attributes associated with fresh LWEs. The obtained results suggested that MIH could be a potential alternative to conventional convective heating for pasteurization applications.
研究领域:
食品科学
·
微生物学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING RESEARCH & DESIGN
·
2019
·
IF 3.073
Tingting Guan,Qin Yan,Lizhi Wan,Songhong Zhang,Linhong Xu,Jianli Wang,Junxian Yun
For preparing cryogel beads by the micro-flow-focusing and cryo-polymerization method, liquid–liquid flow patterns and slug characteristics for the system of Dex-MA and ethyl acetate and the system of Dex-MA-HEMA and ethyl acetate in a cross-shaped square microchannel were studied. The aqueous solutions of Dex-MA-HEMA and Dex-MA were used as the dispersed phase and ethyl acetate as the continuous phase. The formation mechanism of the slug flow was illustrated by analyzing the interaction of the interfacial tension between the dispersed and continuous phases, inertial forces and viscous forces of the dispersed phase and the continuous phase. The flow pattern maps for the two systems were proposed and five regimes were identified, i.e., the slug flow, bubbly flow, jetting flow, unstable flow and stratified flow. The slug lengths and the droplet diameters were also measured experimentally and correlated. The results showed that the formation of the slug flow was related to the interaction of the forces of the continuous phase and dispersed phase. The inertial and viscous force of the continuous phase promoted while the viscous force of the dispersed phase resisted the formation of the slug flow. The interfacial tension and the inertial force of the aqueous phase were shifting their effects which either promoted or resisted the formation of the slug flow. The flow pattern maps have a good agreement with those proposed in the literatures. The velocity of the continuous phase was more influential on the length of the slug segment. The obtained correlation of slug length and the droplet diameter could be helpful to the preparation of the cryogel beads.
研究领域:
生物工程
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化学工程
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产品关联
DOI
高影响因子
Science China-Materials
·
2022
·Vol. 65
·期 9
·2463-2471
·
IF 8.64
Huang Limei,Li Hao,Wang Xinxin,Ding Yuanli,Wang Jianfeng,Jiang Lei
Direct mass exfoliation of graphene from bulk graphite with high yield and productivity for commercial applications is challenging. This work proposes self-grinding exfoliation using the mutual shear friction of graphite particles to fabricate graphene from microcrystalline graphite. The concept is implemented using microbeads as the grinding medium to drive the shear friction between graphite nanocrystals in a high-concentration paste. The proposed approach substantially improves graphene yield from 6.3% to 100% and simultaneously generates a record productivity of 7.5 g h −1 L −1 , achieving total graphite-to-graphene conversion on the kilogram scale. The as-prepared graphene nanosheets have an average lateral size of 298 nm and the same C/O atomic ratio as the pristine graphite. In addition, the well-exfoliated, small nanosheets display good electrical conductivity and exhibit significant potential as conductive additives that improve the specific capacity and cyclic stability of Li-ion batteries better than commercial carbon-based conductive particles.
研究领域:
材料科学
·
能源技术
·
纳米技术
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Dailu Jia,Chao Lei,Wei Ren,Chenghui Liu
In this work, we report a new generation of single microbead bioassay that employs a single BaTiO3 microbead as an optical booster for target biomarker enrichment and optical enhancement toward protein and nucleic acid analysis. The single BaTiO3 microbead can not only concentrate the target molecules by nearly 104-fold but also act as an optical booster to prominently enhance the target-induced fluorescence signal by the whispering gallery mode for improving the excitation efficiency and the microlens effect for promoting the signal collecting efficiency, respectively. Compared with using a conventional single microbead, this optical booster exhibits nearly 2 orders of magnitude higher sensitivity without the assistance of any signal amplification techniques or costly instruments. Moreover, this single microbead optical booster is capable of detecting different kinds of protein and nucleic acid biomarkers in a simple mix-and-read manner, holding great potential for early clinical diagnosis.
CAS / MDL:
研究领域:
生物传感
·
光学技术
·
分子诊断
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产品关联
DOI
PubMed
高影响因子
Bioactive Materials
·
2020
·
IF 8.724
Zhoujun Wang,Wei Sun,Zhiwei Wei,Jianxu Bao,Xin Song,Yupei Li,Haifeng Ji,Jue Zhang,Chao He,Baihai Su,Weifeng Zhao,Changsheng Zhao
Patients with chronic kidney disease are at high risk of hyperkalemia that is associated with various life-threatening complications. Treatments primarily rely on orally administered potassium binding agents, along with low curative effects and various side effects. Herein, direct serum potassium uptake was realized via zeolite–heparin-mimicking-polymer hybrid microbeads. The preparation process involved the synthesis of the heparin-mimicking polymer via the in situ cross-linking polymerization of acrylic acid and N -vinylpyrrolidone in polyethersulfone solution, the fabrication of microbeads via zeolite-mixing, electro-spraying and phase-inversion, and the subsequent aqueous-phase modifications based on ion-exchange and metal-leaching. An ultra-high (about 88%) amount of zeolite could be incorporated and well locked inside the polymer matrix. Potassium uptake capability was verified in water, normal saline and human serum, showing high selectivity and fast adsorption. The microbeads exhibited satisfying blood compatibility, negligible hemolysis ratio, prolonged clotting time, inhibited contact activation, and enhanced antifouling property toward serum proteins and cells. The proposed approach toward zeolite–heparin-mimicking-polymer hybrid microbeads provided a cheap, efficient and safe treatment protocol of hyperkalemia for the high-risk patients.
研究领域:
生物医学工程
·
材料科学
·
肾脏病学
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产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Wenhan Wang,Yongpeng Wang,Mengzhu Liu,Naidi Tan
Nowadays, high-efficiency electromagnetic wave absorption (EWA) materials with simple preparation techniques are desirable for practical applications. However, there are many obstacles need to be overcome. In this work, a novel 3D hollow tubular/spherical structure system has been established by using Fe 3 O 4 as a magnetic loss component, MWCNTs as a dielectric loss component, fly ash cenospheres (FACs) as a structural skeleton through simple self-assembly to achieve excellent EWA properties. Particularly, FACs which derive from power plant solid waste are hollow and insulating that help to regulate the electromagnetic parameters, the conductivity, and the impedance matching characteristics of the composites, as well as reduce the cost. The effect of the unique heterogeneous structure with multiple interfaces on the EWA performance is investigated. The superior absorption performance is primarily due to the synergistic effect of component design and the unique tubular/spherical structure, which provide efficient interfacial polarization loss, dipole polarization loss, moderate conductive loss, good impedance matching, and a large transmission route. The effective absorption bandwidth is as wide as 3.8 GHz at a thickness of 2.0 mm, and the RL min value is −47.35 dB at a thickness of 3.0 mm. The prepared Fe 3 O 4 /MWCNTs/FAC composites have excellent EWA properties that are superior to the majority of recently reported comparable composites. The product meets the requirements of high absorption performance, simple preparation, stable structure, low cost and environmental friendly, which greatly improves its applicability.
研究领域:
材料科学
·
环境科学
·
电磁学
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产品关联
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Wenfeng Ge,Xinyu Zhao,Peng Xu,Shuo Tang,Jingsha Tan,Bing Lei,Zhiyuan Feng,Honglei Guo,Bo Zhang,Guozhe Meng
Regarding the adverse “reverse maze” effect of lamellar fillers to durability of coatings in deep-sea environments, the surface modified spherical hollow glass microspheres were used as fillers to prepare heavy-duty anti-corrosion coatings. The coatings were investigated under simulated deep-sea environments of 14.0 and 20.0 MPa. The results demonstrate that the curved interface of spherical fillers significantly reduces residual solvents and gases within the coatings and inhibits stress concentration at filler edges. The surface modification effectively enhances the interfacial bonding strength and compatibility between the glass microspheres and the coatings, thereby notably prolonging the service life of the coatings in harsh abyssal environments. These findings confirm the validity of the deep-sea coating failure mechanism postulated in our previous research and may provide critical design guidelines for deep-sea coatings.
研究领域:
材料科学
·
海洋工程
·
防腐蚀技术
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Zhou Sha,Xiaochun Gao,Yijie Wang,Xiaotian Guan,Sihao Zhang,Jingru Zhao,Chunnan Wang,Shuqing Sun
Magnetic-fluorescent microbeads had been extensively used in various applications, particularly in the multiple detection of biological molecules. Currently, most commercially available magnetic-fluorescent microbeads had simple structures and the fluorescence intensity was inversely proportional to the concentration of magnetic particles, which affected performances of microbeads. In this work, a three-dimensional capillary microfluidic system was constructed to produce magnetic-fluorescent core-shell microbeads. Magnetic nanoparticles were dispersed in the core of the microbeads, while the shell consisted of quantum dots (QDs). Core-shell structures restricted fluorescence quenching caused by magnetic nanoparticles in the core area. Moreover, the number of cores could be adjusted precisely, which provided an additional encoding method besides the traditional fluorescence encoding. Three types of dual-encoded core-shell microbeads which exhibited excellent uniformity and fluorescence characteristics with additional magnetic response properties were produced. The self-assembly of silica nanoparticles on the surface of microbeads made the introduction of carboxyl groups easy. Furthermore, the capability of these microbeads for multiplex immunoassays was demonstrated using three types of IgG, and a calibration curve for the detection of human IgG was established using a sandwich immunoassay. These results indicated the potential application of this scheme in the field of biomedical detection.
研究领域:
生物技术
·
纳米技术
·
分析化学
·
生物材料科学
·
免疫测定技术
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产品关联
DOI
高影响因子
Materials
·
2022
·Vol. 15
·期 23
·8310
·
IF 3.748
Qianfang Zheng,Shanxia Xiong,Xiaowei Wu,Jianlei Kuang,Wenxiu Liu,Wenbin Cao
Infrared thermal reflective coating is an effective material to reduce building energy consumption and carbon emission. In this work, needle-shaped-rutile-shell-coated hollow glass microbeads (HGM) were prepared by surface modification of HGM and thermohydrolysis of TiCl4, and the possible shell formation mechanism was also proposed. The near infrared (NIR) reflectance of the coated HGM reached 93.3%, which could be further increased to 97.3% after the rutile shell crystallinity was improved by heat treatment. Furthermore, HGM/styrene–acrylic composite reflective coating was prepared on the surface of gypsum board by facile blending and coating methods, and the thermal insulation performance was measured by an indigenously designed experimental heat set-up. The results show that the composite coating prepared by HGM coated with rutile shell shows better NIR reflectance and thermal insulation performance than that prepared by pure organic coating and uncoated HGM. Meanwhile, it also shows better surface hydrophobicity, which is conducive to long-term and stable infrared reflection performance.Keywords:hollow glass microsphere;needle-shaped rutile;near infrared reflectance;thermal insulation coating;hydrophobic properties
研究领域:
材料科学
·
建筑节能
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产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Kai Sun,Lin Wang,Guoliang Wei,Qiang Zhang,Zengyan Wei,Hang Su,Jiayi Geng,S.V. Shil'ko,Gaohui Wu
In this study, one-piece glass cenospheres/aluminum core sandwich is prepared using a pressure infiltration method. In comparison to adhesive bonding, the layers combined by metallurgical bonding are straight and smooth, and the sandwich shows high shear stress of 80.4 MPa. The failure mode is analyzed through a combination of mises stress distribution simulated using the finite element analysis and in-situ strain distribution obtained from a digital image correlation system. After cracks initiated at interfaces, they propagate to nearby layers in the sandwich structure, which can delay the shear failure by avoiding significant damage of core layer.
研究领域:
材料科学
·
力学工程
✓ 已验证
DOI
高影响因子
POLYMER
·
2024
·
IF 4.1
Huilong Shao,Zhifang Fei,Zhen Zhang,Xiaohua Li,Guobing Chen,Kunfeng Li,Shuang Zhao,Zhongyi Luo,Zichun Yang
As a nanoporous material, polyimide (PI) aerogels have excellent thermal and acoustic properties. However, their high air flow resistance is detrimental to the development of their acoustic properties. To enhance the thermal and acoustic insulation properties of PI aerogels, we have selected hollow glass microbeads (HGM) with a low thermal conductivity coefficient to be combined with the PI aerogel, leading to the fabrication of PI/HGM aerogel composite materials. In this study, there are two preprocessing methods for HGM: untreated and aminized (HGM-NH 2 ). These were then individually combined with PI aerogel to fabricate two distinct PI/HGM composite aerogels: a physically blended variant (PIHGM) and a chemically bonded one (PHN). The thermal insulation and acoustic properties of these two composite aerogels were compared. The results show that HGM-NH 2 not only functions as a cross-linking agent but also plays a key role in forming the three-dimensional network structure, which effectively reduces the shrinkage rate and density of the composite aerogel. Moreover, the thermal conductivity of PHN reached a low of 27.92 mW m⁻ 1 K⁻ 1 , which is a reduction compared to PIHGM's thermal conductivity of 29.83 mW m⁻ 1 K⁻ 1 . Moreover, the PHN composite aerogel with 10% HGM addition exhibited an average sound insulation level that was 120% higher than that of PIHGM. The method of incorporating pore structures with different scales also offers valuable insights for enhancing the sound insulation performance of other materials.
研究领域:
材料科学
·
热能工程
·
声学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）