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DEFECT AND DIFFUSION FORUM · 2018 · IF 0

Effect of the Surface Morphology of Zinc Oxide Particles on their Radiation Stability

Vitaly V. Neshchimenko,Chun Dong Li,Mikhail M. Mikhailov,Andrei Dudin

The effect of protons exposure on the diffuse reflectance spectra of the zinc oxide with different shape particles has been investigated. Particles were micro-, nanocrystals, star and flower shape particles. The synthesis of the particles was carried out by the hydrothermal method using zinc acetate chemicals. The surface morphology, surface area and crystal structure of the particles have been investigated. Evaluating the changes in spectral reflectance it was found that the radiation stability of the micro particles is higher than the radiation stability of the other nanostructured particles. The high stability of the micro particles optical properties is due to the effect of low accumulation of radiation-induced defects.

CAS / MDL: 1314-13-2

研究领域: 材料科学 · 辐射物理学

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MICROPOROUS AND MESOPOROUS MATERIALS · 2021 · IF 5.455

Study on the structure and properties of Fe3O4@HMPDA@HA magnetic hollow mesoporous submicron drug-carrying system

Lanlan Lin,Haiyang Li,Sisi Su,Xinyu Wen,Rui Yan,Caihong Tao

In this study, Fe 3 O 4 @HMPDA@HA core-shell submicron particles with a large specific surface area and total pore volumes were prepared. A large cavity structure was constructed between the core and the shell, so the core-shell particles as drug carriers have a large loading capacity. The adsorption properties and mechanism of organic dyes RhB and MB on particles were studied. The results showed that the adsorption capacities of the particles to RhB and MB were 830.65 mg/g and 380.66 mg/g respectively. And doxorubicin (DOX) was used as a targeted drug to research the delivery and sustained-release properties of the particles, the results showed that the loading capacity of DOX was up to 624.75 mg/g. In addition, Hyaluronic acid (HA) can specifically recognize the cancer cells, so the above prepared particles combined magnetic targeting and receptor-mediated targeting. In vitro experiments, the DOX loaded particles had a significant inhibitory effect on HeLa cells.

CAS / MDL: 62-31-7 25316-40-9 9004-61-9 9003-11-6 108-67-8 77-86-1

研究领域: 材料科学 · 药物递送 · 生物医学工程

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Effect of the Surface Morphology of Zinc Oxide Particles on their Radiation Stability

Study on the structure and properties of Fe3O4@HMPDA@HA magnetic hollow mesoporous submicron drug-carrying system