Frontiers of Materials Science
·
2023
·Vol. 17
·期 2
·230641
·
IF 2.7
Li Fangling,Han Xiaoman,Cao Dongdong,Yin Junxia,Chen Li,Li Dongmei,Cui Lin,Liu Zhiyong,Guo Xuhong
Hemostatic dressings with multiple functions are superior to current hemostatic dressings for use in the complex situation of emergency accidents. In particular, the existing dressings lack consideration for the prevention of hypothermic shock after massive hemorrhage. In this study, gelatin (GN) and oxidized pectin (OP) were used for Schiff base cross-linking, and then polyvinyl alcohol (PVA) solution mixed with hemostatic caffeic acid (CA) was introduced to obtain aerogel substrate material (CB) after lyophilization. Polydimethylsiloxane (PDMS) and silver nanowires (Ag NWs) were used to construct a hydrophobic layer, an antibacterial layer and an infrared reflective layer on both sides of CB to prepare a multifunctional aerogel wound dressing with heat preservation, antifouling, hemostasis and antibacterial properties (PDMS-Ag NW-CB). The results showed that the infrared transmittance of PDMS-Ag NW-CB is almost 0, so that thermal energy loss from the body is minimized. The contact angles with water and blood are 129° and 120°, respectively, which have the effect of antifouling. This dressing can absorb blood quickly within 10 min, adhere to and gather platelets, and achieve hemostasis. It has good antibacterial and biocompatibility. Therefore, PDMS-Ag NW-CB has great potential in application to emergency treatment.
研究领域:
生物医学工程
·
材料科学
·
急诊医学
·
伤口护理
·
纳米技术
✓ 已验证
DOI
高影响因子
BURNS
·
2021
·Vol. 48
·期 3
·585-594
·
IF 2.744
Huayu Zhang,Siyuan Yin,Jian Liu,Xia Li,Guoqi Cao,Yongqian Cao,Jiaxu Ma,Ru Song,Guang Zhang,Yibing Wang
Objective With the rapid development of networks in China, the Internet has become an important source of first aid information for scalds. As a country with the largest population, there are a large number of scald cases every year in China. The content analysis of websites aimed to assess the accuracy and quality of the information on scalds available on Chinese websites. Methods Using
研究领域:
公共卫生
·
急诊医学
·
健康传播
·
信息科学
✓ 已验证
DOI
高影响因子
Frontiers in Physiology
·
2024
·
IF 3.2
V. A. Palikov,N. B. Pavlov,R. R. Amirov,A. M. Ismailova,N. A. Borozdina,Yu. A. Palikova,I. A. Dyachenko,O. N. Khokhlova,T. I. Ponomareva,V. A. Rykov,A. T. Logunov,A. N. Murashev,V. M. Baranov
Introduction: Cerebral arterial air embolism (CAE) is a serious and potentially dangerous condition that can interrupt the blood supply to the brain and cause stroke. One of the promising gas mixtures for emergency treatment of air embolism is an oxygen-helium mixture.Methods: We modeled CAE in awake rats by injecting air into the common carotid artery. Immediately after CAE, animals were either untreated or underwent hyperbaria, oxygen inhalation, heated air inhalation, or helium-oxygen mixture inhalation. Body temperature, locomotor activity, respiratory and cardiovascular parameters were monitored in the animals before CAE modeling, and 3 and 24 h after CAE modeling.Results: After 3 hours of CAE modeling in awake rats, depression of the nervous, cardiovascular and respiratory systems, as well as decreased body temperature were observed. 24 h after CAE modeling multifocal cerebral ischemia was observed. Normobaric helium-oxygen mixture inhalation, on par with hyperbaric treatment, restored body temperature, locomotor activity, respiratory volume, respiratory rate, and blood pressure 3 hours after CAE, and prevented the formation of ischemic brain damage lesions 24 h after CAE.Discussion: Thus, inhalation of a heated oxygen-helium gas mixture (O2 30% and He 70%) immediately after CAE improves the physiological condition of the animals and prevents the foci of ischemic brain damage formation.
研究领域:
神经科学
·
急诊医学
·
生理学
·
高压氧医学
✓ 已验证
DOI
高影响因子
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