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Advanced Science · 2023 ·Vol. 10 ·期 10 ·2205343 · IF 15.1

Stretchable and Skin-Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy

Xiaohui Ma,Xiaotong Wu,Shitai Cao,Yinfeng Zhao,Yong Lin,Yurui Xu,Xinghai Ning,Desheng Kong

Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on-demand release of anticancer drugs under electro-thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities.

CAS / MDL: 25316-40-9 9002-89-5
研究领域: 生物医学工程 · 肿瘤学 · 材料科学 · 电子学
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