FOOD AND CHEMICAL TOXICOLOGY
·
2023
·
IF 4.3
Xiaofang Wang,You Weng,Shinan Geng,Caiyun Wang,Cuiyuan Jin,Liyun Shi,Yuanxiang Jin
There is increasing evidence that maternal exposure to environmental pollutants can cause intestinal and metabolic diseases , and these disease risks still exist in offspring . Here, female C57BL/6 mice were orally treated with procymidone (PRO) (10 and 100 mg/kg body weight/day) by dietary supplementation during the gestation and lactation periods. Then, we discovered PRO changed the physiology, intestinal barrier and metabolism both in the generations of F 0 and different developmental stages of F 1 (7 weeks and 30 weeks old, respectively). Maternal PRO exposure affected the growth phenotypes and the glucolipid metabolism related indicators and genes of mice, especially the male mice of F 1 generations. The changes in bile acids (BAs) metabolism demonstrated that PRO disordered glucolipid metabolism through enterohepatic circulation. Furthermore, PRO reduced mucus secretion in the gut and altered the composition of gut microbiota , leading more bacteria to disseminate in the gut and inflammatory responses both in F 0 and F 1 regenerations. And PRO-induced gut microbiota dysbiosis was tightly related to BAs metabolites. Together, the results indicated that PRO destructed the functional integrity of intestinal barrier and the inflammatory reaction was triggered. And then, the disorder of glucolipid metabolism was induced through the BAs enterohepatic circulation. This study indicated that the cross-generation effects of PRO could not be ignored.
研究领域:
环境科学
·
毒理学
·
代谢学
·
微生物学
·
胃肠病学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Juntao Wang,Ruiyang Ma,Yaxing Guo,Fuyuan Zhang,Seid Mahdi Jafari
Accurate monitoring of nitroimidazole antibiotics (NDZs) in environmental and food matrices is critical for safeguarding public health and food safety. In this study, a novel sulfonic acid-functionalized hyper-cross-linked polymer (NDF-TPE-HCP) was synthesized via Friedel-Crafts alkylation reaction. The polymer exhibited unique mixed-mode interactions, which enabled efficient extraction of NDZs. Leveraging its strong ExEf , NDF-TPE-HCP was integrated into a solid-phase extraction system coupled with HPLC for the analysis of NDZs (metronidazole, ronidazole, secnidazole, dimetridazole and ornidazole) in water and fish muscle. The developed method demonstrated a good linearity with NDZs concentrations from 0.07 to 400 ng/g (or ng/mL) with the correlation coefficients ( R 2 ) ≥ 0.9972. Moreover, low limits of detection for the analytes (0.02–5.00 ng/g (or ng/mL)) were achieved. The method recoveries ranged from 85.2 % to 118.0 %, with the relative standard deviation (RSD) ≤ 9.8 %. The NDF-TPE-HCP based method can serve as a robust and sensitive tool for monitoring NDZs residues.
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PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Linna Guo,Qianqian Wang,Qiuhua Wu,Chun Wang,Baojiang Chen
High efficiency enrichment and trace analysis of triazine herbicide residues are crucial for ensuring environmental and food safety. Herein, a series of magnetic hyper-crosslinked polymers (CD-gs-MHCPs) were synthesized with different crosslinkers, which might possess different pore structure and surface area, so they might dispay variable adsorption performance. CD-gs-MHCP2 with dichloroxylene as crosslinker delivered superior adsorption ability for triazine herbicides (THs). The synergistic effect of hydrogen bonds, hydrophobic interaction, π-π stacking interaction and pore adsorption were proved to be the main adsorption mechanism. Combined CD-gs-MHCP2 based magnetic solid-phase extraction (MSPE) with high-performance liquid chromatography, the quantitative analysis of THs in river water and vegetable samples (zucchini, pakchoi) was achieved. Under the optimal conditions, the enrichment factors for three different samples ranged from 94 to 244 and low detection limit (S/N = 3) of the four THs were obtained from 0.05 to 0.15 ng mL −1 for river water and 0.31–3.10 ng g −1 for vegetable samples. The method recoveries were in the range of 86.2 %–120 % with relative standard deviations lower than 7.4 %. This work not only offers a new strategy for fabrication β-CD-based HCPs, but also provided a practical and effective method for efficient isolation and sensitive detection of trace THs residues in complex samples.
研究领域:
环境科学
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分析化学
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材料科学
·
食品安全
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Guijiao Zhao,Chenhuan Wang,Min Kang,Lin Hao,Weihua Liu,Zhi Wang,Xiaodong Shi,Qiuhua Wu
Developing effective methods for highly sensitive detection of phenolic endocrine disruptors (EDCs) is especially urgent. Herein, a magnetic hydroxyl-functional porous organic polymer (M-FH-POP) was facilely synthesized by green diazo-couple reaction using basic fuchsin and hesperetin as monomer for the first time. M-FH-POP delivered superior adsorption performance for phenolic EDCs. The adsorption mechanism was hydrogen bonds, hydrophobic interaction and π-π interplay. With M-FH-POP as adsorbent, a magnetic solid phase extraction method was established for extracting trace phenolic EDCs (bisphenol A, 4- tert -butylphenol, bisphenol F and bisphenol B) in water and fish before ultra-high performance liquid chromatography tandem mass spectrometry analysis. The method displayed low detection limit (S/N = 3) of 0.05–0.15 ng mL −1 for water and 0.08–0.3 ng g −1 for fish. The spiked recoveries were 88.3 %–109.8 % with the relative standard deviations of 2.4 %–6.4 %. The method offers a new strategy for sensitive determination of phenolic EDCs in water and fish samples.
研究领域:
环境科学
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分析化学
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材料科学
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DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2024
·Vol. 47
·期 5
·2300746
·
IF 2.8
Yang Xu,Jingyi Bao,Yuhan Ning,Weiping Wang,Ai-jun Wang,Jiu-ju Feng
In this work, monodisperse and nano-porous poly(bismaleimide-co-divinylbenzene) microspheres with large specific surface area (427.6 m 2 /g) and rich pore structure were prepared by one-pot self-stable precipitation polymerization of 2,2′-bis[4-(4-maleimidophenoxy) phenyl] propane and divinylbenzene. The prepared poly(bismaleimide-co-divinylbenzene) microspheres were employed as dispersive solid-phase extraction (DSPE) adsorbent for the extraction of triazine herbicides. Under optimized conditions, good linearities were obtained between the peak area and the concentration of triazine herbicides in the range of 1–400 µg/L (R 2 ≥ 0.9987) with the limits of detection of 0.12–0.31 µg/L. Triazine herbicides were detected using the described approach in vegetable samples (i.e., cucumber, tomato, and maize) with recoveries of 93.6%–117.3% and relative standard deviations of 0.4%–3.5%. In addition, the recoveries of triazine herbicides remained above 80.7% after being used for nine DSPE cycles, showing excellent reusability of poly(bismaleimide-co-divinylbenzene) microspheres. The adsorption of poly(bismaleimide-co-divinylbenzene) microspheres toward triazine herbicides was a monolayer and chemical adsorption. The adsorption mechanism between triazine herbicides and adsorbents might be a combination of hydrogen bonding, electrostatic interaction, and π-π conjugation. The results confirmed the potential use of the poly(bismaleimide-co-divinylbenzene) microspheres-based DSPE coupled to the high-performance liquid chromatography method for the detection of triazine herbicide residues in vegetable samples.
研究领域:
分析化学
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环境科学
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食品科学
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 4
·1-11
·
IF 6.232
Wang Qianqian,Li Gaigai,Wang Chun,Wu Qiuhua,Wang Zhi
A layered porous organic framework (L-POF) with high surface area and porous volume was used as a novel adsorbent for adsorption of chlorophenols (CPs). The L-POF showed much higher adsorption capacity for four CPs (2-CP, 3-CP, 2,3-CP, 2,4-CP) compared with corresponding amorphous POF and some commercial adsorbents. Then, an L-POF-based solid-phase extraction method combined with high-performance liquid chromatography for analyzing CPs at the wavelength of 280 nm in water and honey samples was established. Under the optimum conditions, four CPs exhibited good linearity in the range 0.10–80.0 ng mL −1 for water and 2–400 ng g −1 for honey samples with determination coefficient r 2 > 0.996. The method has low limits of detection of 0.03–0.10 ng mL −1 for water and 0.5–1.0 ng g −1 for honey samples. The method presented satisfactory precision and accuracy with relative standard deviations ≤ 7.8% and recoveries of 80–115%. High enrichment factors of 123–190 for water and 63–97 for honey were obtained. The validated method was successfully used to determine CPs in water and honey samples. The L-POF also displayed prominent adsorption performance for many other dyes and organic contaminants. This suggests that it can be an ideal candidate as adsorbent for wide application in separation and analysis.
Graphical Abstract
研究领域:
分析化学
·
环境科学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2020
·
IF 6.306
Qianqian Wang,Weihua Liu,Lin Hao,Chun Wang,Qiuhua Wu,Zhi Wang
A magnetic porous organic framework (M-POF) was rationally designed and served as a sorbent for magnetic solid-phase extraction of six nitroimidazoles from chicken meat prior to their assay by high-performance liquid chromatography with diode array detection. The M-POF exhibited good magnetic responsiveness and outstanding affinity to nitroimidazoles with large adsorption capacity up to 36 mg g −1 . Under optimal conditions, the developed method offered good linearity ( r greater than 0.992) in the range of 1.5–100.0 ng g −1 , low limits of detection (S/N = 3) of 0.5–0.8 ng g −1 , low limits of quantification of 1.5–2.5 ng g −1 and high enrichment factors of 80–175 for the nitroimidazoles. The method was successfully applied to analyze nitroimidazoles in chicken meat. The recoveries were 80.2–118% with relative standard deviations lower than 12%. The adsorption mechanism was further explored and the results showed that the M-POF exhibited adsorption potential for compounds with strong polar interactions.
研究领域:
分析化学
·
食品科学
·
材料科学
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2019
·
IF 6.35
Wenqiang Jing,Yanying Zhou,Jiaqin Wang,Miao Ni,Wentao Bi,David Da Yong Chen
Coupling dispersive magnetic solid-phase extraction (DMSPE) to direct analysis in real time mass spectrometry (DART-MS) with a newly developed metal iron probe enables high-throughput, sensitive detection of herbicides such as triazine in environmental waters. Magnetic graphene oxide was used as a dispersive sorbent because it increased adsorption capacity in the DMSPE process. The planar structure and excellent thermal conductivity of graphene oxide facilitated the desorption and ionization of target analytes in DART-MS analysis. The iron probe, which is designed to fit into the moving trail of the DART interface, served as the sorbent collector as well as the support for the magnetic graphene oxide after DMSPE, and was put directly into the DART system. The ratio of magnetic core to graphene oxide in the nanoparticles and other key parameters in DMSPE and DART-MS procedures were systematically investigated and optimized. In addition, the presence of water on the sorbent proves to have a significant effect on DART-MS analysis. No organic solvents are used in this method, and the reusable iron probe is of low cost. Under the optimal conditions, limits of detection were found in the range of 1.6–152.1 ng/L for the triazines. Recovery and reproducibility were found to be in the ranges of 87.5–115.0% and 1.9–10.2%, respectively, for the six herbicides studied. The analytical performance of the DMSPE-DART-MS method indicated that applications for trace analysis of other compounds in liquid samples are also possible.
研究领域:
环境科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Jilong Li,Fengze Wu,Yupu Zhang,Ji Feng,Xiujuan Wang,Yi Yang,Zhibing Wang,Hanqi Zhang
In this study, a novel supramolecular solvent based on surface-active ionic liquid was prepared and used as an extraction solvent for dispersive liquid–liquid microextraction of four triazine herbicides in tea samples. The formation mechanism, microstructure and physicochemical properties of supramolecular solvent were studied. Some parameters, including the molar ratio of surface-active ionic liquid to tetrahydrofuran, volume of supramolecular solvent, vortex time, pH of sample solution, type and amount of salt, were investigated and optimized. The good linearities (r > 0.9990) for the analytes were obtained. The limits of detection and quantification for triazine herbicides were in the range of 1.7–2.1 μg kg −1 and 5.6–7.1 μg kg −1 , respectively. The spiked recoveries were 80.0–119.9 %. The supramolecular solvent prepared in this study has the advantages of simple preparation process, low viscosity and good dispersibility. It can be used for the extraction and enrichment of trace triazine herbicides in tea samples.
研究领域:
分析化学
·
环境科学
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PubMed
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2022
·
IF 8.91
Qianqian Wang,Ranxiao Tang,Mingming Xu,Junmin Wang,Shuofeng Li,Weihua Liu,Lin Hao,Shuaihua Zhang,Junhong Zhou,Chun Wang,Qiuhua Wu,Zhi Wang
Organic micropollutants (OMPs) in water resources are a growing threat to aquatic ecosystems and human health. Efficient removal of polar OMPs is very challenging because of their high hydrophility. Synthesizing novel adsorbent capable of high-efficiently removing hydrophilic and hydrophobic micropollutants is highly desirable for water remediation . Here, using natural proanthocyanidin as building units, a novel hydroxyl-functional porous organic framework (denoted as PC-POF) with amphiphilic feature was synthesized through facile azo coupling reaction. Five sulfonamide antibiotics were selected as model OMPs for adsorption study. Adsorption experiments demonstrated a more rapid and efficient sulfonamides capture ability of the PC-POF than that of the most reported adsorbents due to strong hydrogen bonding, π stacking and electrostatic interactions. The PC-POF can be easily recovered and reused at least 5 times without obvious decline in adsorption performance. Moreover, experiments conducted at environmentally relevant concentrations (μg L −1 ) further confirmed a notable adsorption performance of the PC-POF even when the sulfonamides solution was rapidly passed through the PC-POF packed column. The PC-POF also showed good adsorption performance for other micropollutants like neonicotinoid insecticides, nitroimidazole antibiotics and triazine herbicides, indicating a promising prospect. This work provides a new strategy to construct amphiphilic adsorbent by using renewable resources for pollutants removal .
研究领域:
环境科学
·
水处理
·
材料科学
·
化学工程
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DOI
PubMed
高影响因子
Analytical Methods
·
2015
·Vol. 7
·期 7
·3277-3282
·
IF 1.821
Qingxiang Zhou,Zhi Fang
Triazine herbicides are effective herbicides, which are widely used all over the world, but their residues pose a great threat to the environment and human health. Thus, it is crucial to develop a rapid and sensitive method for monitoring the triazine concentrations in the environment. The present study establishes a simple, sensitive and reliable method for determination of four triazine herbicides including atrazine, prometryn, propazine and simazine in water samples. Ordered titanium dioxide (TiO2) nanotube arrays were prepared using an anodization method and were then used as the adsorbent in the development of a micro-solid phase extraction for the enrichment of triazine herbicides before analysis using high performance liquid chromatography. The experimental results demonstrated that TiO2 nanotube arrays showed good adsorption of triazine herbicides, and the proposed method had satisfactory sensitivity with limits of detection in the range of 0.19–0.50 μg L−1. The proposed method was validated using four real environmental water samples and spiked recoveries were in the range of 84.3–101.9%. All the results demonstrated that the proposed method was an effective analytical tool and would be a useful method for the determination of such pollutants.
研究领域:
环境科学
·
分析化学
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Zan Li,Jun Jia,Mingwei Wang,Hua Zhang,Hongyuan Yan,Fengxia Qiao
A C 8 -and-amino-bifunctionalized ordered mesoporous organosilica (C 8 -AMS) was prepared in a deep eutectic solvent—a green solvent—that was used as the reaction medium for this procedure instead of organic solvents or other catalyst for the first time. This method provided a nontoxic way for C 8 grafting and obtaining an ordered mesoporous organosilica material with both hydrophilic and hydrophobic groups. Besides advantages such as its large surface area, regular and uniform pore size, and hydrothermal stability, the obtained bifunctionalized C 8 -AMS also have two main functional groups in the obtained structure, C 8 and amino, which enriched the adsorption mechanism of the material and as a result improved the adsorption selectivity of C 8 -AMS. Its performance as an adsorbent was estimated in extracting trace triazine herbicides from watermelon using solid-phase extraction (SPE) followed by high-performance liquid chromatography (HPLC). The proposed method provided satisfactory features in terms of linearity (0.01–2.00 μg g −1 ), limits of detection (2.9–5.1 ng g −1 ), accuracy (recovery: 85.7–101.7%), and precision (intra-day and inter-day RSDs: 1.68–2.60% and 3.05–4.01%).
研究领域:
环境科学
·
分析化学
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DOI
PubMed
高影响因子
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