Foods
·
2023
·Vol. 12
·期 7
·1415
·
IF 5.2
Shenglan Lu,Xueying Li,Xunran Wei,Caihuan Huang,Jie Zheng,Shiyi Ou,Tao Yang,Fu Liu
In contrast to their well-known physiological properties, phytochemicals, such as flavonoids, have been less frequently examined for their physiochemical properties (e.g., surface activity). A natural quercetin self-stabilizing Pickering emulsion was fabricated and characterized in the present study. The antisolvent precipitation method was used to modify quercetin (in dihydrate form), and the obtained particles were characterized by light microscope, atom force microscope, XRD, and contact angle. The antisolvent treatment was found to reduce the particle size, crystallinity, and surface hydrophobicity of quercetin. We then examined the effects of the antisolvent ratio, particle concentration, and oil fraction on the properties of the quercetin particle-stabilized emulsions. In addition, increasing the antisolvent ratio (1:1~1:10) effectively improved the emulsification performance of the quercetin particles. The emulsion showed good storage stability, and the particle size of the emulsion decreased with the rising particle concentration and increased with the rising oil phase ratio. The findings indicate that natural quercetin treated with antisolvent method has a good ability to stabilize Pickering emulsion, and this emulsion may have good prospective application potential for the development of novel and functional emulsion foods.Keywords:quercetin;Pickering;antisolvent precipitation;crystalline
研究领域:
食品科学
·
胶体化学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2022
·
IF 6.51
Tingxuan Yan,Haili Wang,Xingfang Song,Tingyuan Yan,Yuwen Ding,Kang Luo,Juan Zhen,Gui He,Libin Nian,Shuangshou Wang,Zhixiang Wang
Flavonoids have many positive pharmacological properties, such as antioxidant, antitumor, and anti-inflammatory activities. However, factors such as low water solubility and low dissolution rate limit their use. To overcome their poor solubility, carrier-free apigenin (API) microparticles and nanoparticles were prepared using three types of antisolvent precipitation technologies: supercritical antisolvent (SCF) technology, ultrasonic-assisted liquid antisolvent (UAL) technology, and high-pressure homogenization (HPH) technology. All three technologies can produce uniform tiny particles. However, the API particles obtained using these different techniques show subtle differences in terms of physical and chemical properties and biological activity. The preparation, characterization, and potential use of API microparticles and nanoparticles to improve in vitro release were studied. The resulting API particles were investigated and compared using Fourier-transform infrared spectroscopy, differential scanning calorimetry, X-ray powder diffraction, and scanning electron microscopy. We determined the optimum conditions for SCF, UAL, and HPH technologies to produce API microparticles and nanoparticles. The antioxidant and antitumor properties of the API particles were also investigated. The results demonstrated that the reduced particle size of the APIs prepared via SCF, UAL, and HPH technologies contributed to the enhanced dissolution rate, which in turn enhanced API bioactivity.
研究领域:
药学
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纳米技术
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药理学
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产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2025
·
IF 5.4
Zhongshan Wang,Changgeng Li,Xiaodi Liu,Wenchao Jia,Lingzhi Huang,Lu Wu,Haiqiang Shi
Processing lignin into nanoparticles (LNPs) offers a promising utilization strategy; however, its structural and molecular weight heterogeneity poses challenges in the formation of uniform LNPs. In this study, industrial kraft lignin was fractionated in stepwise molecular weight (Mw) from low to high and from which LNPs were fabricated via antisolvent precipitation. The results showed that lignin with high Mw benefits the formation of uniform and smaller-sized LNPs. Particularly, the lignin fraction with Mw of 2016 g·mol–1 fails to form LNPs. The main mechanism is that the higher content of hydrophilic groups (mainly phenolic hydroxyl groups) on the lower molecular weight lignin hinders the formation of LNPs. This hypothesis is supported by the successful formation of homogeneous LNPs after low molecular weight lignin acetylation. Fractionation effectively reduces lignin heterogeneity and promotes the formation of LNPs, which would favor the chemical reactivity and properties, enhancing the utilization of industrial lignin.
研究领域:
材料科学
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化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Xiang Cao,Fengqiang Nan,Wenhao Fan,Heng Gao,Ling Chen,Yan Guo,Weidong He
The organic solvent-based nitrocellulose (NC) coatings exhibit a high volatile solvent content, leading to significant environmental pollution. Whereas, existing waterborne NC-based coating have demonstrated poor water resistance and complex application methods. Therefore, this study aims to develop a green and highly water-resistant waterborne NC-based coating system utilizing a simple anti-solvent method with two environmentally friendly plasticizers , namely acetyl tributyl citrate (ATBC) and triethyl citrate (TEC), as film-forming additives. The dynamic light scattering (DLS) studies revealed that the particle size of NC-based nanoparticles increased with an increase in ATBC content, while it remained relatively constant with an increase in TEC content. Moreover, the particle size results demonstrated that the storage stability of aqueous dispersions containing NC/ATBC (NA) was superior to those containing NC/TEC (NT). Additionally, the physicochemical properties of aqueous dispersions-based films (N dis ), including film formation, hygroscopicity , water resistance, transparency, thermal stability, and mechanical properties were evaluated using solvent-based films (N sol ) as control samples. The results demonstrated that the N dis films exhibited a dense and uniform structure, with physical and chemical properties that were essentially comparable to those of N sol films. However, the mechanical properties of N dis films were somewhat influenced by the nanoparticle size, leading to reduced mechanical performance when the particle size of nanoparticles in the aqueous dispersion was excessively large. The equilibrium moisture content for NA and NT films were reduced to 1.119% and 1.872%, respectively, at a relative humidity of 95%, in comparison to pure NC films (3.975%). Simultaneously, water contact angle measurements indicated an increase from 77° for pure NC film to 89° for NA film and 82° for NT film. All films exhibited superior transparency characteristics. Overall, NA films display excellent water resistance and transparency as well as good mechanical properties.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Pengfei Liu,Fei Luo,Yuxin Rao,Huasong Wang,Xue Li,Miaomiao Yu,Xiang Liu,Shangquan Zhao,Shan Fang
Electrolytes play a crucial role in enhancing the cycling stability and overall lifespan of lithium metal batteries (LMBs). However, conventional electrolytes achieve ununiform and low ionic conductivity solid electrolyte interphase (SEI), leading to uncontrolled lithium dendrite growth and dead lithium formation, rendering them inadequate for meeting the performance of high energy density LMBs. Herein, a 1,2-difluorobenzene (1,2-dFBn) is introduced as antisolvent in fluorinated electrolyte which is composed of fluoroethylene carbonate (FEC) and lithium bis(trifluoromethanesulfonyl)imide (LiTFSI). The low energy level of the lowest unoccupied molecular orbital (LUMO) and the high fluorine-donating ability of 1,2-dFBn jointly modify the solvation structure and electrode/electrolyte interphase chemistry. As a result, this simple electrolyte formulation enables the Li||Li symmetric cells exhibit remarkable stability, enduring 700 h of continuous cycling under 2 mA cm–2 and Li||Cu cell achieve an impressive average Coulombic efficiency (CE) of 99.76%. Moreover, the full cell assembled with electrochemically deposited lithium capacity of 5 mAh cm–2 and LiFePO4 (LFP) as cathode achieves exceptional performance, maintaining a discharge specific capacity of 134.9 mAh g–1 while retaining 95.1% capacity at 2C after 1000 cycles. This study offers a plausible ratio design for fluorinated electrolyte, which achieving high CE and long-life LMBs.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Junjie Yan,Heng Zheng,Haojun Luo,Kaitong Xie,Zhifei Zhou,Xuanjie Huang,Xuanrui Zhang,Yuanzheng Yang,Yanxue Wu,Weitong Cai
CsPbBr₃ perovskite solar cells have attracted significant attention due to their outstanding stability and ease of fabrication. However, challenges remain regarding the uniformity of film crystallization and efficiency of the devices, which necessitate further improvements. Antisolvent washing is an effective approach to enhance the crystallization quality of perovskite films. In this study, we present an optimized antisolvent rinsing strategy utilizing a multi-step spin-coating method for the fabrication of CsPbBr₃ films. In the mixed antisolvent of ethyl acetate (EA) and ethanol (EtOH), increasing the volume ratio of EtOH results in a decrease in the number of pinhole defects in CsPbBr₃ films, as well as an increase in the average grain size. When the volume ratio of EA to EtOH is set at 8:2, the average grain size attains an optimal value of 648 nm. Devices based on the FTO/c-TiO₂/m-TiO₂/CsPbBr₃/carbon structure treated with the EA:EtOH (8:2) mixed antisolvent achieved a maximum power conversion efficiency (PCE) of 7.22%. The improvement in device efficiency is primarily attributed to enhanced charge transport and reduced defect density, which collectively suppress non-radiative recombination. Additionally, after 720 hours of storage in ambient air with 40-50% relative humidity, the devices retained 93% of their initial efficiency. This work provides valuable insights into the development of highly efficient and stable CsPbBr₃ perovskite solar cells.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2021
·Vol. 32
·期 18
·185402
·
IF 3.874
Bingquan Han,Lei Zhang,Yuwei Cao,Benyi Li,Zhiyuan Liu,Lingbo Xu,Peng Wang,Ping Lin,Xiaoping Wu,Can Cui
CsPbI3 inorganic perovskites with ideal bandgap and much enhanced thermal stability compared with organic−inorganic hybrid perovskites, have attracted much interest in the field of solar cells. The performances of solar cells highly depend on the quality of perovskite films, yet the research on fabrication methods of inorganic perovskites is far below that of organic–inorganic hybrid counterparts. Antisolvent engineering is a widely used method in controlling the morphology and crystallinity of organic–inorganic hybrid perovskites. Its effect varies with parameters such as the physicochemical properties of antisolvents and the compositions of perovskite precursors. Specially, there lacks a comprehensive study comparing different antisolvents used in low-temperature processed CsPbI3 from dimethylammonium-based precursors. In this work, we used three different antisolvents to control the growth of CsPbI3 films in a low-temperature (<200 °C) processed procedure and systematically compared the properties of resultant films. The green antisolvent ethyl acetate (EA) engineered CsPbI3 films exhibit improved morphology and crystallinity as well as reduced defects, compared with the counterparts processed without antisolvent or those with widely employed toxic antisolvents toluene and chlorobenzene. The EA antisolvent engineering results in efficient CsPbI3 perovskite solar cells with a champion power conversion efficiency of 8.8%. Our work thus provides a green and viable way to prepare high quality CsPbI3 perovskite films for optoelectronic applications.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMBUSTION AND FLAME
·
2022
·
IF 5.767
Lijuan Yan,Baozhong Zhu,Jiuyu Chen,Yunlan Sun
The existence of an oxide (B 2 O 3 ) film covering the boron (B) surface affects its energy release during combustion. Fluoropolymer modification can help to solve the problem. The electrospinning and solvent anti-solvent methods were utilized to modify boron nanoparticles (n-B) using polyvinylidene fluoride (PVDF) as a modified material, which can effectively coat B particles. The thermal behavior, combustion characteristics, and condensed combustion products of the B/PVDF composites were investigated and evaluated. The agglomeration size of B particles can be decreased while its reaction heat and combustion intensity are increased. Significantly, the combustion performance of the B/PVDF composites prepared by the electrospinning method is better than that of the B/PVDF composite prepared by the solvent anti-solvent method. These results can be helpful in promoting the practical application of B.
研究领域:
材料科学
·
燃烧学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Chuiyu Li,Zongqi Chen,Cuicui Zhou,Shiqi Hong,Songwang Yang
In the one-step solution method of perovskite film preparation, antisolvents are widely used to control perovskite crystallization, which directly influences the quality of the perovskite films. Herein, hexafluorobenzene (HFB) was involved in the mixed antisolvent (MAS) system to produce high-quality perovskite films with dual functions of crystallization control and defect passivation. Beyond improving perovskite crystallization and interface contact, a small amount of HFB remained in the perovskite and passivated uncoordinated Pb2+ defects. Consequently, the HFB-involved MAS-derived perovskite films exhibited higher crystallinity, smoother surfaces, better interfacial contacts, and fewer defects than those without HFB additives. These enhancements in film quality significantly improved the open-circuit voltage (VOC) and the fill factor (FF) of the corresponding solar cells, resulting in an increase in power conversion efficiency (PCE) from 23.18% to 24.53%. Furthermore, the solar cells prepared by this method exhibited improved stability. This study highlights a facile and efficient method for simultaneously regulating perovskite crystallization and mitigating defects by incorporating functionalized mixed antisolvents, thus improving the photovoltaic performance of perovskite solar cells.
研究领域:
材料科学
·
能源科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Zhanlin Yang,Guolin Hu,Chenyu Wang,Yuansheng Lin,Zhichao Shi,Jianhui Chen,Yongchuan Liu,Jie Shen,Cuilian Wen,Xiangxin Zhang,Yuanqiang Chen,Baisheng Sa
Localized high-concentration electrolytes (LHCEs) offer a new methodology to improve the functionality of conventional electrolytes. Understanding the impact of antisolvents on bulk electrolytes is critical to the construction of sophisticated LHCEs. However, the mechanism of how antisolvent modulates the electrochemical reactivity of the solvation structure in LHCEs remains unclear. In this work, the key correlation between the physicochemical properties of antisolvents and their corresponding Lithium-ion battery (LIBs) systems has been elucidated by comprehensive multiscale theoretical simulations combined with experimental characterizations. Nine antisolvents (chain ethers and cyclic non-ethers) are investigated in a typical lithium bis(fluorosulfonyl)imide/1,2-dimethoxymethane (LiFSI/DME) system. It is highlighted that the relative molecular masses of antisolvents in the same class are positively correlated with the density. The viscosity of a liquid mixture consisting of DME and antisolvent in the same class is positively correlated with the magnitude of the interaction energy between them. Additionally, the self-diffusion coefficient of Li + is also positively correlated with the sum of the interaction energies between Li + -DME and Li + -FSI − , which is also affected by the class of antisolvent. These results provide deep insights into the behavior and properties of LHCEs, which help to advance the design of high-performance LIBs.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Energy Storage
·
2024
·
IF 8.9
Wenxia Hu,Shimin Huang,Shenggong He,Yiran Zheng,Weishan Zhou,Haixia Cui,Hadia Noor,Xianhua Hou
Aqueous zinc ion battery will be the next-generation energy storage in prospect. Nevertheless, stern parasitic reactions occur on Zn anode at high temperatures, which results in extremely poor zinc anode reversibility. Herein, innovating a trace of triethylamine (TEA) antisolvents considerably resolves foregoing problems; TEA progressively interrelates with free water and coordination water, which diminishes water activity and is conducive to the destruction of Zn 2+ solvation sheath under high temperatures (80 °C). Furthermore, TEA antisolvent electrolyte facilitates uniform Zn 2+ deposition, lessens hydrogen evolution corrosions and eliminates side reactions as far as possible. In the hybrid antisolvent electrolyte, the symmetric Zn/Zn batteries can sustain comparatively longer cycling lifespan of 4000 h at 3 mA cm −2 , 1 mAh cm −2 than that of 135 h without TEA antisolvent. Not only has the Coulombic efficiency made up to 99.95 % in Zn/Cu asymmetric cell over 1600 cycles as well as 94.1 % over 100 cycles at 80 °C, but the Zn/MnO 2 full batteries have also performed constantly for >1000 cycles, showing a 79.03 % capacity sustenance proportion when the current density reached 5 A g −1 . This work opens up a brand-new prospect for high reversible zinc anode and dendrite-free aqueous Zn ion batteries utilizing antisolvent electrolytes.
研究领域:
能源存储技术
·
电化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SUPERCRITICAL FLUIDS
·
2017
·
IF 2.991
Honggang Miao,Zhen Chen,Wenbo Xu,Weiyan Wang,Yaqin Song,Zhixiang Wang
Naringenin (NAR) exhibits many biological and pharmacological activities. However, its poor water-solubility and dissolution rate restrict its oral-intestinal absorption rate and bioavailability. In order to improve its dissolution rate, micronized NAR was successfully prepared using a supercritical anti-solvent process. A mixed acetone/dichloromethane solution and CO 2 were used as the solvent and anti-solvent, respectively. The optimal temperature (35 °C), pressure (12 MPa), drug concentration (15 mg/mL), solution flow rate (1 mL/min), and volume percentage of dichloromethane (45%) were determined using a single-factor method. Under optimal conditions, a mean particle size of 611 ± 32 nm was obtained. XRD and FTIR analyses indicated that the unprocessed NAR and micronized NAR using solution-enhanced dispersion by supercritical CO 2 (SEDS) processes exhibited the same crystal structure and chemical structure, and the samples showed similar DSC thermograms. An in vitro dissolution test showed that micronization significantly enhanced the dissolution of NAR.
研究领域:
药学
·
化学工程
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）