INDUSTRIAL CROPS AND PRODUCTS
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2025
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IF 6.2
Yao Wu,Jinxin Lan,Lvlv Xu,Jinsen Xu,Jun Wang,Xiaojuan Ma,Shilin Cao
Cotton textiles (CTs) with antibacterial and antiviral activity are of great concern due to the needs of the health and hygiene fields. Herein, chitosan oligosaccharide (COS) and divalent zinc ion Zn (II) were innovatively introduced onto the CTs via esterification and coordination reaction initiated by citric acid (CA) and enabled the CTs with prominent antibacterial and antiviral activity ( Escherichia coli : 100 %, Staphylococcus aureus: 100 % , MS2: 99.9 %). The individual COS and Zn (II) modified CTs showed limited antibacterial performance; only concentrated zinc chloride (at least 10 %) treatment could enable the CTs to have a comparative effect with that of the combined treatment of the COS and Zn (II) (1 %). The sequential COS modification and zinc chloride (2 %) treatment was proved to be the optimum because of the 100 % bacterial inhibition rate benefitting from the dual antibacterial and antiviral mechanism originating from COS and Zn (II). The post treatment with excessive zinc chloride could shift the antibacterial mechanism from the dual to the individual action and therefore postponed to inhibit bacterial propagation. More importantly, the post Zn (II) modification could compensate for the strength loss of cotton cloth caused by the acidic degradation of cellulose. The co-modification affects the color and hydrophobicity of the CTs significantly other than the properties of toughness, softness, slipperiness, and drapeability. This strategy has the advantages of an eco-friendly and simple process, which is a good choice for preparing safe, economical, and efficient antibacterial and antiviral CTs.
研究领域:
材料科学
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生物医学工程
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纺织科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Jinxin Lan,Jiazhen Chen,Ruiqi Zhu,Changmei Lin,Xiaojuan Ma,Shilin Cao
The worldwide outbreak of SARS-CoV-2 has attracted extensive attention to antibacterial and antivirus materials. Cellulose is the most potential candidate for the preparation of green, environmentally friendly antibacterial and antiviral materials. Herein, modified cellulosic fibers with sustained antibacterial and antiviral performance was prepared by introducing chitosan oligosaccharide onto the fibers. The two-step method is proved to be more effective than the one-step method for enhanced chitosan oligosaccharide loadings and antibacterial and antiviral activity. In this instance, the modified fibers with 61.77 mg/g chitosan oligosaccharide loadings can inhibit Staphylococcus aureus and Escherichia coli by 100 % after contacting with bacteria for 12 h and reduce the bacteriophage MS2 by 99.19 % after 1 h of contact. More importantly, the modified fibers have washing durable antibacterial and antiviral activity; the modified fibers have 100 % antibacterial and 98.38 % antiviral activity after 20 washing cycles. Benefiting from the excellent performance of the individual fibers, the paper prepared from the modified fibers show great antibacterial (100 %) and antiviral performance (99.01 %) and comparable mechanical strength. The modified fibers have potential applications in the manufacture of protective clothing and protective hygiene products.
研究领域:
材料科学
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生物医学
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2025
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IF 6.9
Yao Wu,Jinxin Lan,Lvlv Xu,Jinfeng Huang,Dongdong Lu,Yonghao Ni,Xiaojuan Ma,Shilin Cao
As a ubiquitous daily necessity, cotton textiles (CTs) provide favorable conditions for microbial growth under suitable temperatures and humidity. For endowing CTs with antibacterial and antiviral activity and durability in an environmentally friendly way, the chitosan-based antibacterial agent was introduced onto the CTs via one one-step esterification reaction. Specifically, the natural long-chain chitosan (CS) was degraded and selectively oxidized through an H 3 PO 4 /HNO 3 -NaNO 2 system to be short-chain oxidized chitosan (OCS) that can provide carboxyl groups reacting directly with hydroxyl on cotton cellulose. OCS with a molecular weight (MW) of 17000 Da and carboxyl content of 29.5 % was proved to be the most active antibacterial agent and endowed the OCS conditioned CTs (OCS-CTs) with excellent antibacterial and antiviral activity ( S. aureus : 100 %, E. coli : 100 %, MS2: 99 %). Besides, benefitting from the stable ester bond, the OCS-CTs showed durable antibacterial properties. More importantly, the modification also makes the OCS-CTs show comparable tensile strength and improved slipperiness, drapeability, and air permeability. This work provides a facile method to prepare an effective chitosan-based antibacterial-antiviral agent with active C O groups, endowing the condition of CTs in one step, which is significant for textile functionalization.
研究领域:
生物材料学
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纺织工程
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微生物学
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产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2023
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IF 19
Ben Wu,Guofang Zhang,Jiawen Ji,Rong-Hua Luo,Junkang Chen,Feng-Liang Liu,Emerson Coy,Sergio E. Moya,Qi Li,Xiaoman Suo,Xinyue Chen,Yong-Tang Zheng,Yang Li,Guocheng Wang
In this study, a novel strategy is developed for the first time, referred to as high-concentration cobalt ion-assisted hydration (HCCAH) utilizing zeolitic imidazolate framework-67 (ZIF-67) as a precursor, to produce independent and flat α-cobalt hydroxide nanosheets (CHN). These nanosheets offer abundant contact sites for binding with virus surface proteins. The formation of CHN involves the in situ transformation from ZIF-67, due to the matching of the hydrolysis rate of ZIF-67 and in situ growth rate of cobalt hydroxide orchestrated by high concentration of cobalt ions. Notably, the CHN contains a higher proportion of trivalent cobalt, which is shown to enhance the binding with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike protein and induce protein structural denaturation, as demonstrated by molecular dynamics (MD) simulation. Antiviral experiments using pseudovirus and authentic viruses have confirmed the promising antiviral performance of CHN. Furthermore, both in vitro and in vivo experiments have demonstrated the excellent biocompatibility of CHN. This research opens up new possibilities for the application of cobalt hydroxide nanosheets and serves as a valuable reference for the design of antiviral nanomaterials.
研究领域:
材料科学
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病毒学
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生物医学工程
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产品关联
DOI
高影响因子
Materials Today Advances
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2021
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IF 7.579
Yaowen Liu,Siying Li,Wenting Lan,Md Alomgir Hossen,Wen Qin,Kangju Lee
In this study, poly (ε-caprolactone) (PCL)/zein/Ag nanoparticle (AgNP) fibrous membranes were prepared by ultrasonication-assisted electrospinning. The effects of the AgNP content and ultrasonication time on the membrane morphology, chemical structure, biodegradability, mechanical properties, antibacterial/antiviral activity, and air filtration performance were studied. The best-performing membrane (AgNP content = 1% (w/v), sonication time = 30 min) exhibited a bead-on-string morphology, an air permeability of 93.6 ± 1.5 mm s −1 , and the Escherichia coli and Staphylococcus aureus removal efficiencies of 98.1 ± 1.2% and 97.4 ± 2.5%, respectively. In an experiment with E. coli phage, the above-mentioned membrane exhibited a 97.1 ± 2.1% virus removal efficiency after 60 min. The high performance of this bead-on-string membrane for air filtration was ascribed to the low packing density due to the presence of open interconnected beaded airflow channels and small beads.
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2021
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IF 13.273
Si-Wei Xiong,Qian Zou,Ze-Gang Wang,Jun Qin,Yang Liu,Nan-Jun Wei,Meng-ying Jiang,Jing-Gang Gai
Wearing surgical masks remains the most effective protective measure against COVID-19 before mass vaccination, but insufficient comfortability and low antibacterial/antiviral activities accelerate the replacement frequency of surgical masks, resulting in large amounts of medical waste. To solve this problem, we report new nanofiber membrane masks with outstanding comfortability and anti-pathogen functionality prepared using fluorinated carbon nanofibers/carbon fiber (F-CNFs/CF). This was used to replace commercial polypropylene (PP) nonwovens as the core layer of face masks. The through-plane and in-plane thermal conductivity of commercial PP nonwovens were only 0.12 and 0.20 W/m K, but the F-CNFs/CF nanofiber membranes reached 0.62 and 5.23 W/m K, which represent enhancements of 380% and 2523%, respectively. The surface temperature of the PP surgical masks was 23.9 ℃ when the wearing time was 15 min, while the F-CNFs/CF nanocomposite fibrous masks reached 27.3 ℃, displaying stronger heat dissipation. Moreover, the F-CNFs/CF nanofiber membranes displayed excellent electrical conductivity and produced a high-temperature layer that killed viruses and bacteria in the masks. The surface temperature of the F-CNFs/CF nanocomposite fibrous masks reached 69.2 ℃ after being connected to a portable power source for 60 s. Their antibacterial rates were 97.9% and 98.6% against E. coli and S. aureus , respectively, after being connected to a portable power source for 30 min.
研究领域:
材料科学
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生物医学工程
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公共卫生
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Pinhong Chen,Zhi Yang,Zhuoxian Mai,Ziyun Huang,Yongshuang Bian,Shangjing Wu,Xianming Dong,Xianjun Fu,Frank Ko,Shiying Zhang,Wenxu Zheng,Shengsen Zhang,Wuyi Zhou
Public health safety issues have been plaguing the world since the pandemic outbreak of coronavirus disease (COVID-19). However, most personal protective equipments (PPE) do not have antibacterial and anti- toxicity effects. In this work, we designed and prepared a reusable, antibacterial and anti-toxicity Polyacrylonitrile (PAN) based nanofibrous membrane cooperated with Ag/g-C 3 N 4 (Ag-CN), Myoporum.bontioides ( M. bontioides ) plant extracts and Ag nanoparticles (NPs) by an electrospinning-process. The SEM and TEM characterization revealed the formation of raised, creased or wrinkled areas on the fiber surface caused by the Ag nanoparticles, the rough surface prevented the aerosol particles on the fiber surface from sliding and stagnating, thus providing excellent filtration performance. The PAN/ M. bontioides /Ag-CN/Ag nanofibrous membrane could be employed as a photocatalytic bactericidal material, which not only degraded 96.37% of methylene blue within 150 min, but also exhibited the superior bactericidal effect of 98.65 ± 1.49% and 97.8 ± 1.27% against E. coli and S. aureus , respectively, under 3 hs of light exposure. After 3 cycles of sterilization experiments, the PAN/ M. bontioides/ Ag-CN/Ag nanofibrous membrane maintained an efficient sterilization effect. Molecular docking revealed that the compounds in M. bontioides extracts interacted with neo-coronavirus targets mainly on Mpro and RdRp proteins, and these compounds had the strongest docking energy with Mpro protein, the shortest docking radius, and more binding sites for key amino acids around the viral protein targets, which influenced the replication and transcription process of neo-coronavirus. The PAN/ M.bontioides /Ag-CN/Ag nanofibrous membrane also performed significant inhibition of influenza A virus H3N2. The novel nanofiber membrane is expected to be applied to medical masks, which will improve human isolation and protection against viruses.
研究领域:
材料科学
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生物学
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医学
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2023
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IF 13.6
Peng Zhao,Rui Wang,Jun Xiang,Jinwei Zhang,Xiaodong Wu,Chaojian Chen,Gongyan Liu
Functional face masks that can effectively remove particulate matter and pathogens are critical to addressing the urgent health needs arising from industrial air pollution and the COVID-19 pandemic. However, most commercial masks are manufactured by tedious and complicated network-forming procedures (e.g., meltblowing and electrospinning). In addition, the materials used (e.g., polypropylene) have significant limitations such as a lack of pathogen inactivation and degradability, which can cause secondary infection and serious environmental concerns if discarded. Here, we present a facile and straightforward method for creating biodegradable and self-disinfecting masks based on collagen fiber networks. These masks not only provide superior protection against a wide range of hazardous substances in polluted air, but also address environmental concerns associated with waste disposal. Importantly, collagen fiber networks with naturally existing hierarchical microporous structures can be easily modified by tannic acid to improve its mechanical characteristics and enable the in situ production of silver nanoparticles. The resulting masks exhibit excellent antibacterial (>99.99%, 15 min) and antiviral (>99.999%, 15 min) capabilities, as well as high PM 2.5 removal efficiency (>99.9%, 30 s). We further demonstrate the integration of the mask into a wireless platform for respiratory monitoring. Therefore, the smart mask has enormous promise for combating air pollution and contagious viruses, managing personal health, and alleviating waste issues caused by commercial masks.
研究领域:
材料科学
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生物医学工程
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环境科学
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医疗技术
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Sciences
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2018
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IF 3.12
Rong Cheng,Mi Kang,Zhi-peng Shen,Lei Shi,Xiang Zheng
Pathogenic viruses in drinking water are great threats to public health. Visible-light-driven photocatalysis is a promising technology for virus inactivation. However, the existing photocatalytic antiviral research studies have mostly been carried out in single-component systems, neglecting the effect of natural organic matter, which exists widely in actual water bodies. In this paper, electrospun Cu-TiO 2 nanofibers were prepared as photocatalysts, and their photocatalytic antiviral performance in the presence of humic acid (HA) was comprehensively studied for the first time. The properties of the reaction mixture were measured during the reaction. In addition, the safety, reliability and stability of photocatalytic disinfection in the mixed system were evaluated. The results showed that the virus removal efficiency decreased with the increase of the HA concentration. The type of reaction solution, such as PBS buffer solution or water, did not affect the removal efficiency noticeably. Under acidic conditions, the electrostatic forces between photocatalysts and viruses were strengthened, leading to higher virus removal efficiency. As the reaction time went on, the pH value in the solution increased first and then tended to be stable, the conductivity remained stable, and the dissolved oxygen increased first and then decreased. The safety test showed that the concentration of Cu ions released into the solution was lower than specified by the international standards. No photoreactivation was observed, and the addition of HA significantly reduced the reutilization efficiency of the photocatalysts.
研究领域:
环境科学
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水处理
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光催化
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病毒学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2023
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IF 15.1
Jinxin Lan,Yao Wu,Changmei Lin,Jiazhen Chen,Ruiqi Zhu,Xiaojuan Ma,Shilin Cao
The worldwide spread of COVID-19 has put a higher requirement for personal medical protective clothing, developing protective clothing with sustained antibacterial and antiviral performance is the priority for safe and sustaining application. For this purpose, we develop a novel cellulose based material with sustained antibacterial and antiviral properties. In the proposed method, the chitosan oligosaccharide (COS) was subjected to a guanylation reaction with dicyandiamide in the presence of Scandium (III) triflate; because of the relatively lower molecular weight and water solubility of the COS, GCOS (guanylated chitosan oligosaccharide) with high substitution degree (DS) could be successfully synthetized without acid application. In this instance, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the GCOS were only 1/8 and 1/4 of that of COS. The introduction of GCOS onto the fiber endowed the fiber with extremely high antibacterial and antiviral performance, showing 100% bacteriostatic rate against Staphylococcus aureus and Escherichia coli and 99.48% virus load reduction of bacteriophage MS2. More importantly, the GCOS modified cellulosic fibers (GCOS-CFs) exhibit excellent sustained antibacterial and antiviral properties; namely, 30 washing cycles had negligible effect on the bacteriostatic rate (100%) and inhibition rate of bacteriophage MS2 (99.0%). Moreover, the paper prepared from the GCOS-CFs still exhibited prominent antibacterial and antiviral activity; inferring that the sheeting forming, press, and drying process have almost no effect on the antibacterial and antiviral performances. The insensitive of antibacterial and antiviral activity to water washing (spunlace) and heat (drying) make the GCOS-CFs a potential material applicable in the spunlaced non-woven fabric production.
研究领域:
材料科学
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生物技术
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纺织工程
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微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）