INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
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2023
·
IF 2.3
Junli Chen,Chunqiao Liufu,Wenfang Zhang,Chunhong Luo,Kaixia Fu,Jianchang Lin,Jiawei Liang,Wei Yang,Fenglan Song,Fan Yang
Objective A partition multi-effect precision-care gel facial mask conforming to facial skin characteristics was prepared using three-dimensional (3D) printing technology. Methods First, the hydrogel matrix and humectant of a 3D-printed gel for facial masks were screened, and three 3D-printed gels of arbutin, hexapeptide, and salicylic acid were prepared with whitening, wrinkle removal, and oil control functions, respectively. Skin irritation tests were performed on the gels. Physicochemical properties such as pH, heat and cold tolerance were evaluated. The efficacy of three 3D-printed gels was assessed by measuring melanin value, wrinkle depression score, and oil secretion. Finally, the facial mask model design and printing parameters were studied, and a partition multi-effect precision-care gel facial mask was printed in line with facial skin characteristics. Results For the 3D-printed facial mask, the gel prescription with 2% hydroxyethyl cellulose gel as matrix and 7% glycerol as humectant was the best. The prepared 3D-printed gel did not irritate the human skin, and its physicochemical properties met the Chinese facial mask industry standard (QB/T2872-2017). We showed that three types of 3D-printed gels containing arbutin, hexapeptide, and salicylic acid could be applied to the corresponding parts of the face to solve different problems, such as facial skin dullness, wrinkles, and oil secretion. Therefore, according to facial physiological characteristics, the facial mask model was designed for the forehead and nasolabial fold, which needs to be anti-wrinkled; the cheek, which needs to be whitened; and the nose and chin, which need oil control. The optimal printing parameters were 0.26 mm nozzle diameter, 90 mm/s printing speed, 30% filling density, 140% wire extrusion ratio, and 0.25 mm layer height. Different skin care effects can be achieved using a three-nozzle printer to print arbutin, hexapeptide, or salicylic acid gel on the mask's forehead and nasolabial fold, cheek, and nose and chin, respectively. Conclusion The 3D-printed partition multi-effect care gel facial mask prepared according to the skin features of different parts of the face can overcome the problem of the single skincare effect of the mass-produced facial masks.
研究领域:
化妆品科学
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生物医学工程
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材料科学
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产品关联
DOI
PubMed
高影响因子
Frontiers in Pharmacology
·
2022
·
IF 5.988
Qian Wang,Xiaoyan Yang,Changwei Zhu,Guodong Liu,Weili Han,Yujun Sun,Lisheng Qian
Benincasa hispida Cogn. ( B. hispida ) is a popular vegetable in China, and studies have been reported on B. hispida polysaccharides (BPS) preparation. However, few studies have been reported on its physicochemical and skincare properties. In this study, we analyzed the physicochemical properties of BPS, free radical scavenging capability, moisturizing and antioxidant activities in vitro and in vivo , respectively. Our results show that BPS was an inhomogeneous acidic polysaccharide that could scavenge a variety of free radicals. Also, BPS had a good moisturizing and antioxidant capability both in vitro and in vivo . Specifically, BPS could alter some key antioxidant enzyme activities and pro-inflammatory factor levels via activating the NRF2/HO-1 pathway, thereby preventing H 2 O 2 -induced reactive oxygen species (ROS) production and apoptosis of HDF-1 cells. Our results suggest that BPS exhibited favorable moisturizing and anti-aging properties and might be an attractive candidate for the development of anti-aging skincare products.
研究领域:
药学
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化妆品科学
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生物化学
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药理学
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL LETTERS
·
2024
·
IF 1.6
Tongtong Liu,Weina Han,Lulu Wang,Xiaoyu Hou,Jin Cao
The aim of this study was to optimize the extraction conditions of 15 preservative allergens from skincare products using response surface methodology (RSM) and determination by gas chromatography – tandem mass spectrometry (GC-MS/MS). The optimal parameters were: 50% acetonitrile (ACN) (% v/v), a solvent/sample ratio of 80, and an extraction time of 10 min. The method provided good linearity (R2 ≥ 0.990) from 0.01 to 2 µg/mL with low limits of detection (0.02–0.2 mg/kg) and quantification (0.04–1 mg/kg). Recoveries ranged from 70.1 to 125.6% and the relative standard deviations (RSDs) varied from 2.0 to 14.9%. The method was successfully applied to eighty skincare products to accurately quantify these preservatives allergens.
研究领域:
分析化学
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化妆品科学
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产品关联
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2018
·Vol. 41
·期 11
·2441-2452
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IF 2.415
Wei Du,Bilin Zhang,Pengqi Guo,Guoning Chen,Chun Chang,Qiang Fu
Dexamethasone-imprinted polymers were fabricated by reversible addition–fragmentation chain transfer polymerization on the surface of magnetic nanoparticles under mild polymerization conditions, which exhibited a narrow polydispersity and high selectivity for dexamethasone extraction. The dexamethasone-imprinted polymers were characterized by scanning electron microscopy, transmission electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction, energy dispersive spectrometry, and vibrating sample magnetometry. The adsorption performance was evaluated by static adsorption, kinetic adsorption and selectivity tests. The results confirmed the successful construction of an imprinted polymer layer on the surface of the magnetic nanoparticles, which benefits the characteristics of high adsorption capacity, fast mass transfer, specific molecular recognition, and simple magnetic separation. Combined with high-performance liquid chromatography, molecularly imprinted polymers as magnetic extraction sorbents were used for the rapid and selective extraction and determination of dexamethasone in skincare cosmetic samples, with the accuracies of the spiked samples ranging from 93.8 to 97.6%. The relative standard deviations were less than 2.7%. The limit of detection and limit of quantification were 0.05 and 0.20 μg/mL, respectively. The developed method was simple, fast and highly selective and could be a promising method for dexamethasone monitoring in cosmetic products.
研究领域:
分析化学
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材料科学
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药物分析
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Yun Gao,Tong Xuan,Fu Chen,Yiping Wu,Xiaoyu Guo,Ying Wen,Haifeng Yang
As one of the most potent carcinogens, aristolochic acid I (AAI) can be founded in many plants, which are widely used as raw materials in traditional Chinese medicine. Surface enhanced Raman scattering (SERS) method would be developed to detect the AAI in rapid way. However, hydrophobic AAI molecule with small scattering section hardly approaches onto the surface of metal nanoparticles, resulting in poor Raman detection sensitivity. In this work, bovine serum albumin (BSA) decorated silver nanoparticles (Ag NPs) with core-shell structure (Ag@BSA NPs) are successfully synthesized. The molecular docking induced strong interaction between BSA and AAI is validated by molecular simulation and Ag@BSA NPs could actively capture AAI and anchor the target molecule into the hot spots of Ag NPs, which greatly improves SERS response of AAI. The dynamic linear range for SERS detection of AAI is from 0.5 to 50 μM (R 2 = 0.9910) and the lowest detectable concentration of 0.28 μM is reached, which meeting the strict limitation of national standard regulation for AAI in cosmetic products. In addition, the method is applied for AAI determination in skin care products and good results are achieved.
研究领域:
分析化学
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纳米技术
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毒理学
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药学
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DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 20
·4962
·
IF 4.2
Yu-Dan Wang,Lu-Sheng Han,Gen-Yue Li,Kai-Li Yang,Yan-Long Shen,Hao Zhang,Jian-Feng Hou,En-Peng Wang
This study was conducted to investigate the differences in chemical composition between red (RGBs) and yellow ginseng berries (YGBs) and their whitening and anti-aging skincare effects. The differences in the chemical composition between RGB and YGB were analyzed by ultra-high-performance liquid chromatography tandem quadrupole electrostatic field orbit trap mass spectrometry (UHPLC-Q-Exactive-MS/MS) combined with multivariate statistics. An aging model was established using UVB radiation induction, and the whitening and anti-aging effects of the two ginseng berries were verified in vitro and in vivo using cell biology (HaCaT and B16-F10 cells) and zebrafish model organisms. A total of 31 differential compounds, including saponins, flavonoids, phenolic acids, and other chemical constituents, were identified between the two groups. Superoxide dismutase (SOD) activity was more significantly increased (p< 0.05) and malondialdehyde (MDA) content was more significantly decreased (p< 0.01) in RGB more than YGB induced by UVB ultraviolet radiation. In terms of whitening effects, YGB was more effective in inhibiting the melanin content of B16-F10 cells (p< 0.01). The results of zebrafish experiments were consistent with those of in vitro experiments and cell biology experiments. The DCFH fluorescence staining results revealed that both ginseng berries were able to significantly reduce the level of reactive oxygen species (ROS) in zebrafish (p< 0.01). Comparison of chemical composition and skin care activities based on RGB and YGB can provide a theoretical basis for the deep development and utilization of ginseng berry resources.
研究领域:
药用植物学
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化妆品科学
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分析化学
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细胞生物学
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动物模型
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）